1.Histopathologic Findings & Expression of bcl-2 of the Endometrium Analysis of 1,000 consecutive biopsies of uterine bleeding .
Hye Kyung LEE ; Dong Geun LEE ; Ho LEE ; Sang In SHIM
Korean Journal of Pathology 1998;32(3):208-214
We evaluated 1,000 consecutive endometrial curettage samples obtained over a 30 month period. The clinico-pathologic correlation was analysed according to Hendrickson's five criteria based on the practical view. The causes of uterine bleeding in decreasing order of occurrence were as follows: 1) hormonal imbalance lesions (49.2%) encompassing glandular and stromal breakdown suggesting anovulatory bleeding, proliferative phase endometrium, and disordered proliferative endometrium, 2) pregnancy associated lesions (24.2%), 3) organic lesions (13.5%), 4) endometrial hyperplasia (6.9%), and 5) inadequate specimen (6.2%). According to age, pregnancy related lesions were most frequent in the third decade. In the fourth, fifth, and sixth decades, hormonal imbalance lesions were the most common cause. In approximately 30% of the samples, there were two or three morphologic patterns such as anovulatory bleeding with an endometrial polyp, postabortal bleeding with inflammation, and glandular-stromal dissociation with a polyp, which suggested there was a variable histologic morphology in the same disease spectrum. Using immunohistochemical techniques we studied the hormonal dependency of bcl-2 oncoprotein in anovulatory bleeding, endometrial hyperplasia, and proliferative endometrium. 70% of anovulatory bleeding specimens showed weak positivity in the epithelial cytoplasm, and all cases of endometrial hyperplasia and carcinoma showed a strong positivity. These results suggest that there is a estrogenic hormonal dependency of apoptosis in the endometrium.
Apoptosis
;
Biopsy*
;
Curettage
;
Cytoplasm
;
Endometrial Hyperplasia
;
Endometrium*
;
Estrogens
;
Female
;
Hemorrhage
;
Inflammation
;
Polyps
;
Pregnancy
;
Uterine Hemorrhage*
2.Acquired Ectopic Nail as a Complication after Excision of Epidermal Cyst.
Tae Gwang KWON ; Taek Geun LEE ; Hyun Ho SON ; Sook Kyung LEE
Korean Journal of Dermatology 2014;52(3):199-200
No abstract available.
Epidermal Cyst*
3.Island flaps of the hand.
Geun Jik LEE ; Jong Moon LEE ; Seung Ha PARK ; Woo Kyung KIM ; Chun Eun CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(5):1125-1135
No abstract available.
Hand*
;
Surgical Flaps*
4.Complete Remission of Recalcitrant Plantar Wart Treated with Quadrivalent Human Papilloma Virus Vaccine.
Taek Geun LEE ; Hyun HWANGBO ; Se Won JUNG ; Sook Kyung LEE
Korean Journal of Dermatology 2014;52(6):442-443
No abstract available.
Humans
;
Papilloma*
;
Warts*
5.CT Findings of Breast Lipoma: A Case Report.
Kyung Joo PARK ; Moon Ok LEE ; Chun Hwan HAN ; Jeong Geun YI ; Joo Hyuk LEE
Journal of the Korean Radiological Society 1994;30(3):589-590
Lipoma is one of the unusual benign breast neoplasms and usually manifests at fatty breast of women at the age of 40 to 60. We experienced a case of large breast lipoma nearly replacing the whole left breast parenchymal tissue with mammographic finding of well-defined radiolucent mass, sonographic finding of hyperechoic mass with disorganized echopattern and computerized tomographic finding of very low attenuation mass, characteristic to adipose tissue, in a young woman of her dense breast.
Adipose Tissue
;
Breast Neoplasms
;
Breast*
;
Female
;
Humans
;
Lipoma*
;
Ultrasonography
6.2 cases of omphalocele diagnosed prenatally by ultrasonography.
Yong Wook KIM ; Do Geun LEE ; Eun Joo LEE ; Seo Kyung KIM ; Jae Sung KANG
Korean Journal of Obstetrics and Gynecology 1992;35(1):144-149
No abstract available.
Hernia, Umbilical*
;
Ultrasonography*
7.Solitary fibrous tumor of the nasal cavity: A report of 1 case.
Seung Hwan LEE ; Sung Geun KIM ; Hyung Seok LEE ; Kyung Sung AHN ; Chan Pil PARK ; Eun Kyung HONG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(6):1338-1344
No abstract available.
Nasal Cavity*
;
Solitary Fibrous Tumors*
8.Histopathological Differences between Silicone Granuloma and Paraffinoma.
Yeon Mee KIM ; Hye Kyung LEE ; Hye Je CHO ; Je Geun CHO
Korean Journal of Pathology 1996;30(5):427-436
During the past two decades, silicone (polydimethylsiloxane) has become one of the most extensively applied biomaterials. Although pure silicone is relatively inert and usually causes only minimal tissue reactions, it has been reported to evoke a definite foreign body reaction. We studied five cases of silicone-induced granulomas in various sites; two in the breast, one in the breast and axillary lymph nodes, one in the subcutis of the abdomen, back and extremities and one in the eyeball, to illustrate the salient histopathologic features of reactions to silicone with particular emphasis to its differences from paraffin granuloma. For this, 17 paraffinomas were also studied. Tissue reaction to silicone liquid and gel was characterized by numerous round to oval empty cystic vacuoles, mild to moderate fat necrosis, foreign body reaction, a variable degree of mononuclear inflammatory cell infiltration and mild focal fibrosis. The cystic spaces were relatively uniform and showed a snow-man like appearance. In contrast to the silicone granulomas, the paraffinomas, also refered to as sclerosing lipogranulomas showed diffuse sclerosis and frequent calcification around the cystic vacuoles. The cystic spaces in paraffinomas were swiss cheese-like configuration, and the content of the cystic spaces was dirty and frequently calcified. However, there were certain similarities between these two types of granulomas particularly in the early phases of the reaction, therefore, the history of silicone injection or implant, is sometimes critical to the diagnosis of silicone granuloma. Despite great technologic advances in the manufacturing of prostheses and medical equipment, droplets and/or particles of silicone still escape into the body tissues in a variety of ways; therefores, the pathologist should always wonder whether the histologic reaction observed is due to silicone or to some other foreign material including paraffin.
9.Limb-Body Wall Malformation Complex: Two autopsy cases and its pathogenesis.
Geun Shin LYU ; Nam Hoon KIM ; Eun Kyung HONG ; Jung Dal LEE
Korean Journal of Pathology 1993;27(6):638-644
Limb-body wall malformation complex(LBWC), also know as the amniotic band syndrome, is a poorly defined, sporadic group of congenital anomaly characterized by a collection of protean fetal malformation, deformation and disruption. Accurate diagnosis is often difficult because of its variable presentation pattern and the absence of exactly same case. We report two autopsy cases. One revealed body wall, cardiac, and craniofacial anomalies with anencephaly, and amniotic adhesive band attached to craniofacial defect of the fetal part without evidence of amniotic rupture. The other exibited abdominal wall defect with omphalocele, visceral, postural, and limb anomalies together with neural tube defect in the lumbosacral region. The pathogenesis of this syndrome was discussed in detail.
10.A Case of Primary Mucinous Adenocarcinoma of the Colon in Children.
Chi Ho YOON ; Kyung Ae LEE ; Jung Mo RYU ; Soon Hee CHOI ; Kyu Geun CHO
Journal of the Korean Pediatric Society 1985;28(11):1136-1140
No abstract available.
Adenocarcinoma, Mucinous*
;
Child*
;
Colon*
;
Humans
;
Mucins*