No abstract available.
Child* ; Humans ; Reye Syndrome*

No abstract available.
Colposcopy* ; Early Diagnosis* ; Uterine Cervical Neoplasms*

This study was performed to evaluate the diagnostic value of colposcopy by comparing colposcopic findings with cytology, histology of colposcopically directed biopsy and final biopsy result on hysterectomy. From January 1, 1988 to August 31, 1996, the colposcopic examinations was undertaken in 1200 patients, excluding grossly visible carcinoma of the cervix. The result were as follows : 1. Colposcopic examinations were satisfactory in 95.4% and unsatisfactory in 4.58%. 2. The accuracy rate of cytologic diagnosis was 73.1% and colposcopic impression was 93.1%. 3. The false negative rate of colposcopic impression was 2.6%, much less than 24,7% of cytologic examination. 4. The cytologic accuracy rate in cervicitis was higher than that of colposcopic impression but the accuracy rate of colposcopic impression in diagnosis of cervical intraepithelial neoplasia was higher than that of cytology. 5. Among 97 cases in which colposcopically directed biopsy were performed, more advanced lesion were disclosed in 12 cases(12.4%).
Biopsy ; Cervical Intraepithelial Neoplasia ; Cervix Uteri ; Colposcopy* ; Diagnosis ; Early Diagnosis* ; Female ; Humans ; Hysterectomy ; Uterine Cervical Neoplasms* ; Uterine Cervicitis

No abstract available.
Fever* ; Humans

OBJECTIVE: Human papillomavirus (HPV) has been identified more than 100 HPV subtypes. The distributions of subtypes are different according to nations and regions. We analysed subtype of infection with HPV among women who live in Pusan and surburbs of Pusan. We accessed the clinical usefulness of HPV DNA chip test as a supplementary method of Pap smear in the evaluation of cervical lesion. METHOD: This study was undertaken from January 2002 to January 2005 and the samples were collected from the patients who had abnormal Pap smear. We analysed subtypes of 143 positive cases with HPV DNA chip (Biomedlab) test and estimated pathologic reports of 115 patients except 28 patients who had not biopsy. We investigated pathologic results of 54 of 115 patients who had atypical squamous cells / low grade squamous intraepithelial lesion (ASC/LSIL) in Pap smear and examined high risk HPV in 54 pathologic results. RESULTS: The prevalence of HPV subtypes was 42 cases of HPV-16, 20 cases of HPV- 58, 16 cases of HPV-52, 10 cases of HPV-35, 9 cases of HPV-56, 7 cases of HPV-51, 6 cases of HPV-18 in descending order of incidence in high risk HPV group and 3 cases of HPV-6, 3 cases of HPV-42, 2 cases of HPV-34, 2 cases of HPV-43 in descending order of incidence in low risk HPV group. The results of HPV DNA chip test and 115 pathologic reports were estimated by comparative study. A pure infection with low risk HPV group was detected in low grade lesion. Infection with high risk HPV group was also detected in low grade lesion but was mainly detected in high grade lesion. The pathologic results of 54 patients who had ASC / LSIL in Pap smear were 13 patients had above high grade lesion include 2 cases of invasive carcinoma so false negative rate of Pap smear in the detection of high grade lesion was 24%. CONCLUSION: HPV subtypes were detected HPV 16, 58, 52, 35, 56, 51, 18 types in descending order of incidence and prevalence. Mass study and integrated data from larger population and various regions in many hospitals will be needed. And the supplementary use of HPV DNA chip test may provide clinical usefulness because it can reduce the false negative rate of Pap smear and improve the positive predictive value in the detection of high grade cervical lesion and it enables to decrease the incidence of cervical cancer.
Biopsy ; Busan ; Cervix Uteri* ; DNA* ; Female ; Human papillomavirus 16 ; Human papillomavirus 18 ; Human papillomavirus 6 ; Humans ; Incidence ; Oligonucleotide Array Sequence Analysis* ; Prevalence ; Uterine Cervical Neoplasms

No abstract available.
Cytokines* ; Mast Cells*

No abstract available.
Ectopia Cordis* ; Hernia, Umbilical*

No abstract available.
Humans

Peritoneal origin serous papillary carcinoma is an uncommon primary malignancy occurring in the abdominal or pelvic peritoneum lining. It is characterized by peritoneal carcinomatosis with massive ascites, uninvolved or minimally involved ovary, and is histologically indistinguishable from ovarian serous tumors. Better recognition of this phenomenon in recent years has contributed to an increasing diagnostic frequency. We describe a rare case of peritoneal origin serous papillary carcinoma with unusual clinical presentations involving a solitary primary tumor originating from the peritoneal lining of the sigmoid colonal mesentery, without pelvic lymph node involvement or distant metastasis. Because of the location and morphological similarity, it was misdiagnosed as an ovarian malignancy. We aim to assist in the diagnosis of this disease with the following case report, thereby improving the management of patients with this condition.
Ascites ; Carcinoma ; Carcinoma, Papillary* ; Colon, Sigmoid ; Diagnosis ; Female ; Humans ; Lymph Nodes ; Mesentery ; Neoplasm Metastasis ; Ovarian Neoplasms* ; Ovary ; Peritoneum

OBJECTIVE: This study was to determine if placental histologic acute inflammation is related to maternal and fetal serum cytokine levels in preterm labor. METHODS: In 2003-2004, 32 consecutive patients at 20-36 weeks with progressive labor and tocolytic failure were recruited. Maternal serum sampled during the labor, and fetal serum of umbilical vein were assayed by ELISA for levels of soluble interleukin-1beta and interleukin-6. Acute placental inflammation was scored by two groups blinded to clinical data, and the average scores analyzed for relationships to serum cytokine levels. RESULTS: Fetal level of interleukin-1beta was higher with grade 3-4 acute amnionitis than with grade 0-2 (p=0.022 and p=0.023). Fetal levels of both cytokine were higher in grade 3-4 umbilical vasculitis (interleukin-1beta p=0.008 and interleukin-6 p=0.03). In contrast, maternal serum interleukin levels were not associated with presence or severity of histologic evidence of acute placental inflammation. CONCLUSION: We conclude that fetal serum, but not maternal serum interleukin levels, was correlated with histologic evidence of acute placental inflammation. This result may be used to detect acute placental inflammation as an indirect indicator.
Amnion ; Chorioamnionitis ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Inflammation* ; Interleukin-1beta* ; Interleukin-6* ; Interleukins ; Obstetric Labor, Premature ; Pregnancy ; Umbilical Veins ; Vasculitis