No abstract available.
Cephalosporins*

Orthopaedic wire has been used widely as a good internal fixator in cases of fracture, the ligament reconstruction, and for the stabilization of cervical spine. But if it is used inappropriately, a wire can be easy to fail by elongation, untwisting, or breakage. Among them, the most common failure of wire is breakage. To clarify the mechanism and the causes of wire failure, the authors analysed serial roentgenograms and scanning electronmicroscopic findings of broken wire in total 13 cases, which were experienced at the department of orthopaedic surgery, St. Mary's Hospital, Catholic University Medical College From January 1981 to December 1987. The results obtained were as follows :1. The mechanism of wire failure were classified into the 4 types ; minor continual flexing motion in 6 cases, repeated minor back and forth torsion in 1 case, tension failure in 2 cases and combined type in 4 cass. 2. The causes of wire failure were in appropriate use and inadequte application, a lack of s ufficient mechanical strength, micromotion due to inadequate postoperative imm obilization, early mobilization before tissue healing as well as certain injuries to the wire during handling in operation.
Early Ambulation ; Fatigue ; Internal Fixators ; Ligaments ; Spine

The stature, span, lower limb length, sitting height, head length and head breadth of 411 Korean elementary school girls ranging from 7 to 10 years of age were measured biometrically and the indices among all of the items were calculated to investigate the physical growth status. The following conclusion have been obtained. 1. The average statures were 117.40cm in 7, 122.72cm in 8, 126.76cm in 9 and 132.92cm in 10 years of age groups, and the annual average stature growth was 5.17cm. 2. The average spans were 113.12cm in 7, 118.70cm in 8, 124.26cm in 9, 130.46cm in 10 years of age groups, and the annual average span growth was 5.78cm. 3. The average lower limb lengths were 62.96cm in 7, 66.80cm in 8, 69.09cm in 9 and 73.13cm in 10 years of age groups, and the annual average lower length growth was 3.39cm 4. The average sitting heights were 65.82cm in 7, 68.56cm in 8, 70.18cm in 9 and 73.13cm in 10 years of age groups, and the annual average sitting height growth was 2.43cm. 5. The average body weights were 21.22kg in 7, 24.13kg in 8, 25.54kg in 9 and 29.27kg in 10 years of age groups, and the annual average body weight growth was 2.68kg. 6. The average head lengths were 16.29cm in 7, 16.38cm in 8, 16.47cm in 9 and 16.60cm in 10 yeras of age groups, and the annual average head length growth was 0.10cm. 7. The average head breadth were 14.50cm in 7, 14.65cm in 8, 14.67cm in 9 and 14.81cm in 10 years of age groups, and the annual average head breadth growth was 0.10cm. 8. While both relative span and lower limb length increased with age and the relative sitting height slightly decreased with age. 9. The relative body weight increased with age. 10. The head type depended on cephalic index was belonged to hyperbrachycephaly, and showed no differrences with age in all of the groups. 11. The relative span was over 96 in all age groups, and the value increased slightly with age. 12. The average annual growth showed remarkable high value between 9 to 10 years of age in the items of stature, span, lower limb length, sitting height and body weight.
Body Weight ; Female* ; Head ; Humans ; Lower Extremity

PURPOSE: Regular cancer screening for workers can help prevent cancer or allow early treatment, and is thus beneficial in improving health, reducing costs, and increasing companies' productivity. However, there has been little research on cancer screening rates of workers and related factors. The purpose of this study was to identify cancer screening rates and relevant factors among manufacturing workers. METHODS: Using a questionnaire, data were collected from 335 workers aged over 40 years recruited from seven manufacturing companies. The collected information included cancer screenings (stomach, colorectal, breast, and cervical), attitude towards cancer screening, and demographic and job characteristics. RESULTS: 72.5% of workers received stomach cancer screening (SCS), and 43% received colorectal cancer screening (CRCS). Among 86 women, 68.6% received breast cancer screening and cervical cancer screening. The attitude towards cancer screening was 29.5+/-3.78. Workers aged over 51, married, and those working in mobile manufacturing were more likely to have undergone SCS. Workers aged over 51, married, those working in mobile manufacturing, those in workplaces with more than 1,001 employees, and those with more positive attitudes toward cancer screening were more likely to have undergone CRCS. Finally, attitude affected cervical cancer screening. CONCLUSION: Workers in small-sized workplaces had lower cancer screening rates. Thus, follow-up research should assess the health environment of workplaces and develop educational programs on cancer screening that reflect attitudes towards screening.
Aged ; Breast Neoplasms ; Colorectal Neoplasms ; Early Detection of Cancer ; Efficiency ; Female ; Follow-Up Studies ; Humans ; Mass Screening ; Surveys and Questionnaires ; Stomach Neoplasms ; Uterine Cervical Neoplasms

No abstract available.
Stomach Neoplasms* ; Tuberculosis, Pleural*

No abstract available.
Animals ; Liver* ; Rats*

No abstract available.
Animals ; Cerebral Cortex* ; Glutamic Acid* ; Glycine* ; Kynurenic Acid* ; Perfusion* ; Rats*

No abstract available.
Multiple Myeloma* ; Osteosclerosis*

In view of the potential of replicase protein as a diagnostic reagent for human caliciviruses (HuCVs), we have cloned and over-expressed this gene from the Snow Mountain-like Korean strains in Escherichia coli as a fusion protein with glutathione S-transferase (GST, and described the preliminary antigenic characterization of the recombinant products. Each 470bp fragment corresponding to highly conserved region of RNA-dependent RNA polymerase was generated by RT-PCR from stools of two diarrheal children, cloned in pMOSBlue T-vector, and subcloned between the EcoRI and SalI restriction sites of pGEX-47-3, a GST gene fusion vector, yielding pGCVpol. This construct expressed a Snow Mountain-like HuCV replicate under the control of the IPTG-inducible pac promoter. An extract prepared by sonication of the E. coli cell inclusion bodies bearing pGCVpol products was purified and analyzed by SDS-PAGE. After Coomassie blue staining, it was shown that the recombinant replicase migrated on the gels with an approximate molecular mass of 46.5 kDa, that was subsequently cleaved into a 26 kDa GST fragment and a 20.5 kDa replicase protein upon digestion with thrombin protease. The replicase was recognized on immunoblotting with the sera from symptomatic children with the HuCV-associated diarrhea but not by asymptomatic sera from adults. The results presented the first biological activity of individually expressed HuCV replicase subunit and provided important reagents for diagnosis of HuCV infection.
Adult ; Child ; Clone Cells ; Diagnosis ; Diarrhea ; Digestion ; Electrophoresis, Polyacrylamide Gel ; Escherichia coli ; Gels ; Gene Fusion ; Glutathione Transferase ; Humans ; Immunoblotting ; Inclusion Bodies ; Indicators and Reagents ; RNA Replicase ; Snow* ; Sonication ; Staphylococcal Protein A ; Thrombin

The therapeutie efficacy of ranitidine was evaluated itn 48 in- and out- patients with endoscopically diagnosed 18 cases of gaetric ulcer and 30 casea of ducnienal ulcer. In the open study, every pabenta was treated with ranitidine 150 mg b.i.d. for 4 weeks, and waa followed up by gastroscopy after 4 weeks of the treatment. The reeults obtained were summarized as follows; 1) 15 out of 18 cases (83. 3%) of gastric ulcers and 26 out of 30 cases (86. 7%) of duodenal ulcers had been completely healed up in 4 weeks. 2) There was a significant relationship between healing of ulcer and the relief of symptoms (x =6.12, P<0.005).3) There were no significant untoward reactions, efther subjective or objective, to the administration of the drug, except one case of severe epigastic discomfort. In conclusion ranitidine appears to be fairy effective and safe for the treatment of patient with peptic ulcr diseases.
Duodenal Ulcer ; Gastroscopy ; Humans ; Peptic Ulcer* ; Ranitidine* ; Stomach Ulcer ; Ulcer