1.Epidemiology of Narcotics and Psychedelics.
Journal of the Korean Medical Association 1998;41(4):360-364
No abstract available.
Epidemiology*
;
Hallucinogens*
;
Narcotics*
2.Sociopsychiatric characteristics of admitted psychoactive substance abusers.
Hyuk LEE ; Kyung Bin KIM ; Yu Kwang KIM
Journal of Korean Neuropsychiatric Association 1991;30(1):229-242
No abstract available.
3.Prevalence and physician's detection rate of alcoholism in patients of a general hospital.
Suk Koon CHO ; Kyung Bin KIM ; Hwan Il CHANG
Journal of Korean Neuropsychiatric Association 1993;32(6):904-912
No abstract available.
Alcoholism*
;
Hospitals, General*
;
Humans
;
Prevalence*
5.MR Imaging of the Early Rheumatoid Arthritis: Usefulness of Contrast Enhanced Fat Suppressed SPGR Imaging.
Kyung Bin JOO ; Chang Kok HAHM ; Sun Mi KIM ; Seong Tae KIM
Journal of the Korean Radiological Society 1995;32(6):959-963
PURPOSE: To evaluate value of post-contrast 3-Dimensional fat suppressed Spoiled GRASS (FS SPGR) in detectiong subtle bony erosion and tenosynovitis of hands and wrists due to early rheumatoid arthritis. MATERIALS AND METHODS: Fourteen MR iraagings of the hands and wrists were performed in 7 early rheu- matoid arthritis without any abnormalities in plain radiography and in 7 healthy volunteers. All subjects underwent MR sequence of coronal 3D FS SPGR with and without contrast enhancornear in 1.5T MR unit. We evaluated the number of the bony erosion and tenosynovitis respectively in pre- and post-contrast FS SPGR images. RESULTS: The abnormal enhancing areas were not demonstrated in 7 healthy volunteers. Seven patients had 25 bony erosions in pre-contrast FS SPGR and 52 bony erosions with tenosynovitis (n=10) in post-contrast FS SPGR. Enhancing joint spaces were shown in 8 cases CONCLUSION: Post-contrast FS SPGR was better than pre-contrast FS SPGR in the evaluation of early rheumaotid arthritis and is valuable as a baseline study.
Arthritis
;
Arthritis, Rheumatoid*
;
Hand
;
Healthy Volunteers
;
Humans
;
Joints
;
Magnetic Resonance Imaging*
;
Poaceae
;
Radiography
;
Tenosynovitis
;
Wrist
6.Regulation of Estrogen Receptor mRNA in Rat Anterior Pituitary Gland.
Min Seok CHUN ; Duck Bae PARK ; Yong Bin PARK ; Kyung Yoon KAM ; Chang Mi KIM ; Kyung Ja YOO
Journal of Korean Society of Endocrinology 1997;12(4):518-527
The estrogen receptor (ER) is present in a wide variety of mammalian tissues and is required for the physiological responses of estrogen, including estrogen-induced tissue-specific changes in gene expression. But most of our knowledge on the regulation of ER mRNA levels comes from in vivo steroid replacement experiments or cancer cell lines that express the ER. Thus the present study was attempted to determine 1) the anterior pituitary ER mRNA levels during rat estrous cycle 2) if estradiol itself directly modulates the ER mRNA levels in cultured rat anterior pituitary using RT-PCR method. In rats with 4 day estrous cycle, the ER mRNA levels in anterior pituitary gland reached to maximum at proestrus 11:00h just before serum estradiol concentration showed the highest. From then, the ER mRNA levels gradually declined during the rest of the proestrus. On the other hands, in cultured rat anterior pituitary cells, the ER mRNA levels were significantly decreased by the treatment of estradiol. These results indicate that the surge of estradiol was proceeded by the increase in pituitary ER mRNA levels during the proestrus and in cultured anterior pituitary cells, estrogen might be involved in the down-regulation of the ER mRNA levels.
Animals
;
Cell Line
;
Down-Regulation
;
Estradiol
;
Estrogens*
;
Estrous Cycle
;
Gene Expression
;
Hand
;
Pituitary Gland, Anterior*
;
Proestrus
;
Rats*
;
RNA, Messenger*
7.A Case of Primary Cutaneous Plasmacytoma.
Han Seung LEE ; Ho Jung LEE ; Jung Bin KIM ; Woo Ick YANG ; Seung Kyung HANN
Annals of Dermatology 1996;8(4):287-290
A 66-year-old female patient had a firm, non-tender, dome shaped mass on the scalp. The lesion had enlarged slowly for 2 years, and measured about 4 × 6 cm. The histologic finding of the skin biopsy specimen demonstrated an infiltration of immature plasma cells in the dermis, which express monoclonal cytoplasmic lambda light chain by immunohistochemical stainings, and staging work-up after the biopsy revealed no evidence of disease in other foci. The mass on the scalp was treated successfully by radiation therapy, with the diagnosis of primary cutaneous plasmacytoma.
Aged
;
Biopsy
;
Cytoplasm
;
Dermis
;
Diagnosis
;
Female
;
Humans
;
Plasma Cells
;
Plasmacytoma*
;
Scalp
;
Skin
8.Identification of Autoantibodies to Melanocytes and Characterization of Vitiligo Antigen in Vitiligo Patients.
Nam Soo KIM ; Seung Kyung HANN ; Yoon Kee PARK ; Sung Bin IM
Korean Journal of Dermatology 1995;33(2):248-259
BACKGROUND: Recently, it has been suggested that autoantibodis face of melanocytes are prevent in the sera of vitiligo patients. However, these autoantibodies exist, whether they are specific for vitiligo a vitiligo patients possess them. In addition, the specificity of the iti lecular weight of the antigen are all unsolved areas demanding further. OBJECTIVE: To investigate the possible role of autoimmune microvitiligo, this study was designed to verify the presence of auto and vitiligo antigen from the surface of melanocytes, the specificity of gene specific antigens on the sunever, it is not known whether ents, and what percentage of goantigen and the exact moier research. anisms in the development of bodies in vitiligo patients, the utoantibodies and vitiligo anti. METHODS: Indirect immuvofluorescent microscopy, flow cytoriiety, and ELISA was done to compare the reactions between melanocytes and sera. SDS-PAC island immunoblotting were used for the identification of vitiligo antigen. RESULTS: Vitiligo sera showed more prominent fluorescence and higher optical density on the surface of melanocytes than normal sera. Forty-four percent of vitiligo sera was directed to melanocytic surface antigen with a molecular weight of 65kDa. The sition assay using rabbit antimelanocytic antibody showed an inhibition of the reaction betw er vitiligo sera and melanocytes in ELISA and immunoblotting. CONCLUSION: A surface antigen of 65kd was identified from melanocytes and 44.4% of the vitiligo sera showed positive reactions to this antigen.
Antigens, Surface
;
Autoantibodies*
;
Enzyme-Linked Immunosorbent Assay
;
Fluorescence
;
Humans
;
Immunoblotting
;
Melanocytes*
;
Microscopy
;
Molecular Weight
;
Sensitivity and Specificity
;
Vitiligo*
9.MRI finding of spinal extradural granulocytic sarcoma: case report.
Jong Sung KIM ; Hyun Chul RHIM ; Seung Ro LEE ; Kyung Bin JOO ; Chang Kok HAHM
Journal of the Korean Radiological Society 1993;29(5):914-916
A 31-year-old woman with surgically proven spinal extradural granulocytic sarcoma was examined with magnetic resonance (MR) imaging. This patient had no evidence of systemic leukemia. The signal intensities of the mass on T1-weighted and gradient echo images were higher than those of spinal cord, which were different from iso-intensity of cases reported by other authors.
Adult
;
Female
;
Humans
;
Leukemia
;
Magnetic Resonance Imaging*
;
Sarcoma, Myeloid*
;
Spinal Cord
10.Death by Subdural Hematoma with Metastatic Carcinoma of Unknown Origin: An Autopsy Case Report.
Hyun Jung LEE ; Kyung Bin KIM ; Jong Hyeok PARK ; Hongil HA
Korean Journal of Legal Medicine 2014;38(2):83-87
Dural metastasis associated with chronic subdural hematoma is very rare in patients with malignant neoplasms; it may be difficult to distinguish malignant neoplasms from chronic subdural hematoma. Chronic subdural hematoma is usually a late manifestation of malignant tumors, which contributes to the severity of the prognosis. The scans obtained by using magnetic resonance imaging or computed tomography may be misleading when a subdural hematoma masks the underlying tumor. Herein, we report a case of a subdural hematoma with dural metastasis of unknown origin in a 45-year-old woman; however, the neoplasm was not detected until autopsy.
Adenocarcinoma
;
Autopsy*
;
Female
;
Hematoma, Subdural*
;
Hematoma, Subdural, Chronic
;
Humans
;
Magnetic Resonance Imaging
;
Masks
;
Middle Aged
;
Neoplasm Metastasis
;
Prognosis