1.The effects of commonly eaten Korean foods on glycemic index and beta-cell secretory function in normal and diabetic patients
Hyung Joon RYU ; Duk Hee HAN ; Kyung Ah HAN ; Doo Man KIM ; O Keum SONG
Journal of the Korean Diabetes Association 1991;15(1):131-133
No abstract available.
Glycemic Index
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Humans
2.Misconception and Knowledge about Diabetes in Elderly Diabetics.
Journal of the Korean Geriatrics Society 1999;3(4):39-49
BACKGROUND: Diabetes was common problem in older adults. However, there were widespread misconceptions about possible consequences of uncontrolled hyperglycemia. So we studied the frequency of misconceptions and their relationship with knowledge about diabetes. glycemic control, and clinical characteristics of elderly diabetic patients. METHODS: Among 127 medical records of elderly diabetic patients. we investigated age. sex, duration of diabetes. onset age of diabetes, body mass index. We interviewed about history of admission due to diabetes information source of diabetes, level of education, experience of education for diabetes and self care status such as self monitoring of blood glucose and urine glucose. daily foot care and measurement of body weight. For evaluation of misconception and knowledge. we used structured interviews based on validated scales. RESULTS: There was no relationship between frequency of misconception and age, sex, duration of diabetes, information source of diabetes level of education, experience of education for diabetes and self care status such as self monitoring of blood glucose.and urine glucose, daily foot care and measurement of body weight. But the score of knowledge was related with good glycemic control state (Hb Alc < 7.0%) and good self-care status (self monitoring of blood glucose, and measurement of body weight) And linear relationship between the frequency of misconception and score of knowledge was found ( p<0.001) CONCLUSION: Our study suggested that the glycemic control was related with the score of knowledge, but not with frequency of misconception. But further study about other misconceptions will be needed for improving patients quality of life and reducing long-term complication.
Adult
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Age of Onset
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Aged*
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Blood Glucose
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Body Mass Index
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Body Weight
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Education
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Foot
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Glucose
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Humans
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Hyperglycemia
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Medical Records
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Quality of Life
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Self Care
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Weights and Measures
3.A Study on Related Factors to Overweight for Primary School Children.
Mee Ah PARK ; Hyun Kyung MOON ; Kyu Han LEE
Journal of the Korean Dietetic Association 1998;4(2):145-151
The purpose of this study was to investigate the related factors to child overweight through investigation of children aged 6-12. Data on physical examinations, family history and dietary habits were obtained. Children were classified into normal(98 persons) and overweight(118 persons) group using the combination of height for age, weight for age and weight for height standard by the World Health Organization. Children's height, weight and BMI exhibited a significant difference between groups except children aged 8 for height. Unbalanced diet was a risk factors for overweight(Odd ratio : 1.765, 95% CI : 1.022~3.048). Number of brothers showed negative significance especially in two brothers compared to that of one(Odd ratio : 0.456, 95% CI : 0.209~0.995). But Birth weight, feeding practice, overeating, taking nutrition pills, sleeping time, mother's education level and employmental status didn't have any difference. We found out there were different risk factors between obese and overweight group. They should be divided into different groups in studying risk factors. And we should pay much attention to overweight children in order to prevent improving to obesity.
Birth Weight
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Case-Control Studies
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Child*
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Diet
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Education
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Employment
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Food Habits
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Humans
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Hyperphagia
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Obesity
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Overweight*
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Pediatric Obesity
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Physical Examination
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Risk Factors
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Siblings
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World Health Organization
4.The Small Rice Bowl-Based Meal Plan was Effective at Reducing Dietary Energy Intake, Body Weight, and Blood Glucose Levels in Korean Women with Type 2 Diabetes Mellitus.
Hee Jung AHN ; Kyung Ah HAN ; Hwi Ryun KWON ; Kyung Wan MIN
Korean Diabetes Journal 2010;34(6):340-349
BACKGROUND: The typical Korean diet includes rice, which is usually served in a rice bowl. We investigated the effects of a meal plan using rice bowls of varying sizes on dietary energy intake (EI), body weight (BW), and blood glucose levels. METHODS: Forty-two obese women with type 2 diabetes mellitus were randomly assigned to use either a 200 mL small rice bowl (SB), a 380 mL regular rice bowl (RB), or to a control group (C). Both intervention groups were asked to reduce their EI by 500 kcal/day for 12 weeks and simple instructions for using the assigned bowl were provided. Dietary EI and proportion of macronutrients (PMN) were estimated from 3-day dietary records. RESULTS: Reduction of EI was more prominent in the SB group compared to the RB and C group, although EI decreased significantly from baseline in all groups. Carbohydrate and fat intakes of the SB group were decreased greater than those of the RB and C group. However, changes in PMN were not significant across the 3 groups. Reduction of BW and HbA1c levels in the SB group was more prominent compared to the C group. Although, BW and HbA1c were decreased significantly from baseline in both bowl groups. There was no statistical difference between the two groups. CONCLUSION: The small rice bowl-based meal plan was effective at reducing EI, BW, and blood glucose levels, and the observed reductions in EI, carbohydrate, and fat intake were greater than those of the regular rice bowl-based meal plan.
Blood Glucose
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Body Weight
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Diabetes Mellitus, Type 2
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Diet, Diabetic
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Diet
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Energy Intake
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Female
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Humans
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Meals
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Obesity
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Weight Loss
5.Differential Cardiovascular Outcomes of Each Antihypertensive Drug Class in Patients With Hypertension and Breast Cancer Undergoing Doxorubicin-Containing Chemotherapy
Journal of Breast Cancer 2023;26(5):492-503
Purpose:
The preemptive use of renin-angiotensin system (RAS) inhibitors may reduce doxorubicin (DOX)-related cardiotoxicity. Using the national insurance claims data of Korea, this study compared cardiovascular (CV) outcomes following the use of four major antihypertensive drug classes in patients with hypertension and breast cancer who underwent DOX-containing chemotherapy.
Methods:
A total of 4,722 patients with hypertension and breast cancer who underwent DOXcontaining chemotherapy were included. The outcomes were compared between patients who used RAS inhibitors, calcium channel blockers (CCBs), beta-blockers (BBs), and thiazide and thiazide-like diuretics (TDs). The primary outcome was a composite of incident heart failure and serious ventricular arrhythmias, including ventricular tachycardia and fibrillation, ischemic heart disease, and stroke.
Results:
In the propensity score-matched population, there were no significant differences in the primary outcome between RAS inhibitor and CCB users; however, patients with diabetes who used CCBs had a worse primary outcome than those who used RAS inhibitors (adjusted hazard ratio [aHR], 1.93; 95% confidence interval [CI], 1.06–3.51). BB and TD users had a worse primary outcome compared with RAS inhibitor (aHR, 1.88; 95% CI, 1.30–2.71 in BB users and aHR, 2.55; 95% CI, 1.37–4.75 in TD users) or CCB (aHR, 1.54; 95% CI, 1.09–2.16 in BB users and aHR, 2.08; 95% CI, 1.13–3.82 in TD users) users.
Conclusion
RAS inhibitors are preferred for the treating hypertension and improving CV outcomes in patients with hypertension and breast cancer undergoing DOX-containing chemotherapy, particularly in patients with comorbid diabetes. However, CCBs are equivalent to RAS inhibitors and are more favorable than BBs and TDs in terms of improving CV outcomes.
6.The Effects of Resistance Training on Muscle and Body Fat Mass and Muscle Strength in Type 2 Diabetic Women.
Hwi Ryun KWON ; Kyung Ah HAN ; Yun Hyi KU ; Hee Jung AHN ; Bo Kyung KOO ; Ho Chul KIM ; Kyung Wan MIN
Korean Diabetes Journal 2010;34(2):101-110
BACKGROUND: Our goal was to investigate the effects of low intensity resistance training on body fat, muscle mass and strength, cardiovascular fitness, and insulin sensitivity in type 2 diabetes. METHODS: Twenty-eight overweight women with type 2 diabetes were randomly assigned to a resistance training group (RG, n = 13) or a control group (CG, n = 15). RG performed resistance training using elastic bands, of which strength was equal to 40 to 50% of one repetition maximum (1RM), for three days per week. Each exercise consisted of three sets for 60 minutes. We assessed abdominal fat using computed tomography, muscle mass using dual-energy X-ray absorptiometry, and muscle strength using Keiser's chest and leg press. Insulin sensitivity was measured using the insulin tolerance test, and aerobic capacity was expressed as oxygen uptake at the anaerobic threshold (AT-VO2) before and after the 12-week exercise program. RESULTS: The age of participants was 56.4 +/- 7.1 years, duration of diabetes was 5.9 +/- 5.5 years, and BMI was 27.4 +/- 2.5 kg/m2, without significant differences between two groups. During intervention, a greater increase in muscle mass and greater decreases in both total fat mass and abdominal fat were observed in RG compared to those of CG (P = 0.015, P = 0.011, P = 0.010, respectively). Increase in 1RM of upper and lower extremities was observed in the RG (P = 0.004, P = 0.040, respectively), without changes in AT-VO2 and insulin resistance in either group. CONCLUSION: In conclusion, the low intensity resistance training was effective in increasing muscle mass and strength and reducing total fat mass without change of insulin sensitivity in type 2 diabetic patients.
Abdominal Fat
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Absorptiometry, Photon
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Adipose Tissue
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Anaerobic Threshold
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Diabetes Mellitus, Type 2
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Female
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Humans
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Insulin
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Insulin Resistance
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Leg
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Lower Extremity
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Muscle Strength
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Muscles
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Overweight
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Oxygen
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Resistance Training
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Thorax
7.Small Rice Bowl-Based Meal Plan versus Food Exchange-Based Meal Plan for Weight, Glucose and Lipid Control in Obese Type 2 Diabetic Patients.
Hee Jung AHN ; Kyung Ah HAN ; Hwi Ryun KWON ; Bo Kyung KOO ; Hyun Jin KIM ; Kang Seo PARK ; Kyung Wan MIN
Korean Diabetes Journal 2010;34(2):86-94
BACKGROUND: The Korean National Health and Nutrition Examination Surveys reported 65% of daily energy intake (EI) as carbohydrate (CHO) in the Korean population and main source of CHO was cooked rice. We used a standardized-small sized rice bowl for diet education and investigated its effectiveness on body weight, glucose and lipid, compared to the conventional food exchange system in type 2 diabetes obese women. METHODS: Type 2 diabetic women with body mass index > or = 23 kg/m2 were randomly assigned to small rice bowl-based meal plan (BM) and food exchange-based meal plan (ExM) group. Both groups were asked to reduce their EI by 500 kcal/day for 12 weeks. The macronutrient composition was instructed: 55 to 60% of EI as CHO, 15 to 20% as protein, and 20 to 25% as fat. BM group received only a simple instruction for application of the rice bowl. Nutrient intake was estimated with the 3-day dietary records. RESULTS: Finally, 44 subjects finished the study. The percent reduction of body weight was significant both BM group (-5.1 +/- 2.6%) and ExM group (-4.8 +/- 2.8%) after 12 weeks (P < 0.001) but there was no difference between the groups. There was no difference in the proportional change of CHO, protein and fat in EI between the groups. Additionally, the change of HbA1c and low density lipoprotein-cholesterol were not significantly different between the two groups. CONCLUSION: The BM group was as effective as ExM for body weight and glucose control in type 2 diabetes obese women.
Body Mass Index
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Body Weight
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Diabetes Mellitus, Type 2
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Diet, Diabetic
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Diet
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Diet Records
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Energy Intake
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Female
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Glucose
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Humans
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Meals
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Obesity
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Weight Loss
8.Effects of Aerobic Exercise on Abdominal Fat, Thigh Muscle Mass and Muscle Strength in Type 2 Diabetic Subject.
Hwi Ryun KWON ; Kyung Wan MIN ; Hee Jung AHN ; Hee Geum SEOK ; Bo Kyung KOO ; Ho Chul KIM ; Kyung Ah HAN
Korean Diabetes Journal 2010;34(1):23-31
BACKGROUND: Aerobic exercise can effectively reduce visceral fat. However, few studies have examined the effect of daily physical activity on obesity and cardiopulmonary function in the subjects with diabetes. We examined the effect of moderate intensity of walking in obese diabetes patients by monitoring of daily activity and measuring the change in abdominal fat area, muscle are and maximal muscle strength. METHODS: We randomly assigned 27 obese women with type 2 diabetes to an aerobic exercise group (AG, n = 13) and control group (CG, n = 14). The AG performed moderate intensity walking for 60 minutes per exercise, 5 times per week, and for 12 weeks. The activity energy expenditure was monitored by a multi-record accelerometer. The CG maintained routine daily activities. At the time of the initiation of the study and after 12 weeks of exercise, the aerobic exercise capacity was assessed using oxygen consumption rate at anaerobic threshold (VO2-AT). The abdominal fat area and the quadriceps muscle area were measured by computed tomography, and the maximum muscle strength of the upper and lower limbs was measured by a chest press and a leg press, respectively. RESULTS: The mean age of the study subjects was 56.6 +/- 8.0 years, the mean duration of diabetes was 6.3 +/- 6.0 years, and the body weight index (BMI) was 27.3 +/- 2.7 kg/m2. The BMI of the AG was significantly decreased (P = 0.003). In the AG, the visceral fat area and subcutaneous fat area were also significantly decreased (P = 0.018 and P < 0.001, respectively) but not in CG. VO2-AT of the AG was significantly improved, while that of the CG did not change (P = 0.009 and P = 0.115, respectively). The quadriceps muscle mass and the maximal muscle strength of the AG did not change, however, the CG showed a significant decrease. Duration of moderate intensity exercise was correlated with the decrease in total abdominal fat area (r = -0.484; P = 0.011) and that of high intensity exercise was correlated with improvement of cardiopulmonary function (r = 0.414; P = 0.032). CONCLUSION: Daily moderate intensity aerobic exercise is effective at reducing abdominal fat mass, while high intensity exercise improves cardiopulmonary function.
Abdominal Fat
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Anaerobic Threshold
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Body Weight
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Diabetes Mellitus, Type 2
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Energy Metabolism
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Exercise
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Female
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Humans
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Intra-Abdominal Fat
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Leg
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Lower Extremity
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Motor Activity
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Muscle Strength
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Muscles
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Obesity
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Oxygen Consumption
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Quadriceps Muscle
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Subcutaneous Fat
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Thigh
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Thorax
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Walking
9.Effects of Aerobic Exercise on Abdominal Fat, Thigh Muscle Mass and Muscle Strength in Type 2 Diabetic Subject.
Hwi Ryun KWON ; Kyung Wan MIN ; Hee Jung AHN ; Hee Geum SEOK ; Bo Kyung KOO ; Ho Chul KIM ; Kyung Ah HAN
Korean Diabetes Journal 2010;34(1):23-31
BACKGROUND: Aerobic exercise can effectively reduce visceral fat. However, few studies have examined the effect of daily physical activity on obesity and cardiopulmonary function in the subjects with diabetes. We examined the effect of moderate intensity of walking in obese diabetes patients by monitoring of daily activity and measuring the change in abdominal fat area, muscle are and maximal muscle strength. METHODS: We randomly assigned 27 obese women with type 2 diabetes to an aerobic exercise group (AG, n = 13) and control group (CG, n = 14). The AG performed moderate intensity walking for 60 minutes per exercise, 5 times per week, and for 12 weeks. The activity energy expenditure was monitored by a multi-record accelerometer. The CG maintained routine daily activities. At the time of the initiation of the study and after 12 weeks of exercise, the aerobic exercise capacity was assessed using oxygen consumption rate at anaerobic threshold (VO2-AT). The abdominal fat area and the quadriceps muscle area were measured by computed tomography, and the maximum muscle strength of the upper and lower limbs was measured by a chest press and a leg press, respectively. RESULTS: The mean age of the study subjects was 56.6 +/- 8.0 years, the mean duration of diabetes was 6.3 +/- 6.0 years, and the body weight index (BMI) was 27.3 +/- 2.7 kg/m2. The BMI of the AG was significantly decreased (P = 0.003). In the AG, the visceral fat area and subcutaneous fat area were also significantly decreased (P = 0.018 and P < 0.001, respectively) but not in CG. VO2-AT of the AG was significantly improved, while that of the CG did not change (P = 0.009 and P = 0.115, respectively). The quadriceps muscle mass and the maximal muscle strength of the AG did not change, however, the CG showed a significant decrease. Duration of moderate intensity exercise was correlated with the decrease in total abdominal fat area (r = -0.484; P = 0.011) and that of high intensity exercise was correlated with improvement of cardiopulmonary function (r = 0.414; P = 0.032). CONCLUSION: Daily moderate intensity aerobic exercise is effective at reducing abdominal fat mass, while high intensity exercise improves cardiopulmonary function.
Abdominal Fat
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Anaerobic Threshold
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Body Weight
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Diabetes Mellitus, Type 2
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Energy Metabolism
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Exercise
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Female
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Humans
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Intra-Abdominal Fat
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Leg
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Lower Extremity
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Motor Activity
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Muscle Strength
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Muscles
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Obesity
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Oxygen Consumption
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Quadriceps Muscle
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Subcutaneous Fat
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Thigh
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Thorax
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Walking
10.The Effects of Low-Calorie Diets on Abdominal Visceral Fat, Muscle Mass, and Dietary Quality in Obese Type 2 Diabetic Subjects.
Hee Jung AHN ; Youn Ok CHO ; Hwi Ryun KWON ; Yun Hyi KU ; Bo Kyung KOO ; Kyung Ah HAN ; Kyung Wan MIN
Korean Diabetes Journal 2009;33(6):526-536
BACKGROUND: Weight loss through low-calorie diets (LCDs) decreases visceral fat (VF). However, the effects on muscle mass, changes of dietary quality, and insulin sensitivity are unknown for Korean obese type 2 diabetic subjects. Therefore, this study examined such effects of LCDs. METHODS: A total of 30 obese type 2 diabetic subjects (body mass index, 27.0 +/- 2.2 kg/m2) were randomly assigned to an LCD or control group. Subjects on LCDs took 500~1,000 kcal fewer energy than their usual dietary intake (1,000~1,500 kcal/day) over the course of 12 weeks. The abdominal VF and femoral muscle mass were evaluated by computed tomography, and insulin sensitivity was assessed using an insulin tolerance test (Kitt; rate constant for plasma glucose disappearance, %/min). Dietary nutrient intake consumed by subjects was assessed by 3-day food records. RESULTS: The percent VF reduction was -23.4 +/- 17.2% in the LCD group and -9.8 +/- 11.8% in the control group after 12 weeks (P < 0.001, P = 0.002). However, significant decrease in femoral mass or proportional change of marcronutrient intake and mean adequacy ratio were not found in the LCD group, as compared to the control group. Insulin sensitivity improved in the LCD group, as compared to the control group (P = 0.040). CONCLUSION: LCD effectively improved insulin sensitivity and reduced abdominal VF without reduction of femoral muscle and dietary quality in obese type 2 diabetic subjects.
Caloric Restriction
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Diabetes Mellitus, Type 2
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Glucose
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Insulin
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Insulin Resistance
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Intra-Abdominal Fat
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Muscles
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Plasma
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Weight Loss