There have been some pros and cons about the of routine intravenous pyelography in benign prostatic hyperplasia. Herein we analyzed 196 patients who underwent intravenous pyelography before prostatectomy at Dept. of Urology, Seoul National University Hospital from Jan. 1976. to Dec. 1983. Of 196 patients 140 (72%) showed normal upper tract with cystogram compatible with benign prostatic hyperplasia(Group I), 22(11%) dilated upper tract(Group II), 20(10%) incidental upper tract abnormalities including 9 urolithiasis(Group III), and 14(7%) completely normal findings(Group IV). There was a significant relationship between Group II and serum BUN value. Cystoscopy revealed evidence of prostatic enlargement in 14 cases and other abnormal findings including bladder tumor which were not shown on routine IVPs. We conclude that intravenous pyelography is not always necessary in diagnosis of benign prostatic hyperplasia when urine analysis and serum BUN are normal Instead, we recommend KUB to observe renal outline and calculi, and preoperative routine cystoscopy to evaluate prostatic enlargement and bladder neck obstruction.
Calculi ; Cystoscopy ; Diagnosis ; Humans ; Prostatectomy ; Prostatic Hyperplasia ; Seoul ; Urinary Bladder Neck Obstruction ; Urinary Bladder Neoplasms ; Urography* ; Urologic Diseases* ; Urology

Although, renal carcinoma represent 2 to 3% of all human cancers, the impredictable nature, and unique clinical and biological features of renal carcinoma place it among the most interesting of human malignancies. Total surgical excisions offers the only certain cure for nephrocarcinoma, but additional benefit may be achieved by utilization of adjuvantive methods including surgical excision of metastasis, radiation, chemotherapy, and immunotherapy. So, 28 patients with renal cell carcinoma were analyzed retrospectively in order to 1) determine the effectiveness of systemic chemotherapy-hormonal and non-hormonal, 2) identify the clinical features of renal cell carcinoma that may be important in prognosis and 3) characterize the paraneoplastic features of renal cell carcinoma. The classic triad of signs and symptoms including pain, hematuria, and palpable tumor mass presents in only 7%. Paraneoplastic syndrome occurred in up to 28.6% Metastasis was present at diagnosis in 25 % of the cases and developed within 1 year in an additional 10.7%. Surgery was employed to 23 patients for the purpose of complete cure of the disease or palliation and adjuvantive therapy was employed either to palliate symptoms or to attempt eradication of metastatic deposits to 9 patients with or without surgery. Most of metastatic disease was unresponsive objectively to either primary nephrectomy or to a variety of chemotherapy trial. Improving diagnostic capabilities and the introduction of more sophisticated diagnostic equipment promise to provide still earlier identification of patients with renal cell carcinoma and to allow surgical intervention at curable stages of disease.
Carcinoma, Renal Cell* ; Diagnosis ; Diagnostic Equipment ; Drug Therapy ; Hematuria ; Humans ; Immunotherapy ; Neoplasm Metastasis ; Nephrectomy ; Paraneoplastic Syndromes ; Prognosis ; Retrospective Studies

A Clinical observation on 20 cases of ureteroileocutaneostomy was made who had been admitted to the Dept. of Urology from March 1, 1973 to August 31, 1977. 1. The most common underlying disease was bladder carcinoma, and only one case was neurogenic bladder. 2. Among the patients only one case was undertaken original Bricker's operation, and the others were by the modified conjoined ureteroileocutaneostomy. 3. Major complications were incisional hernia, ureteroileal obstruction, sepsis and stoma hernia with ureteral obstruction. 4. In the patient with unilateral ureteroileal obstruction, hypertension was corrected after nephrectomy.
Hernia ; Humans ; Hypertension ; Nephrectomy ; Sepsis ; Ureteral Obstruction ; Urinary Bladder ; Urinary Bladder, Neurogenic ; Urology

Sarcoma of prostate and bladder is rare malignant disease and its prognosis is very poor because of rapid growing tendency. Recently the combined treatment of surgery, radiotherapy and chemotherapy has increased the survival rate, significantly A clinical observation and retrospective analysis were made on 9 patients with primary sarcoma of bladder and prostate which were admitted during the period of 8 years and 8 months from January. 1971 to August, 1979. The results obtained were as follows: 1. The age distribution ranged from 2 years to 51 years and the prostate sarcoma was most common in the young age group upto 15 years. 2. The presenting symptoms were dysuria in 6 patients (67%), acute urinary retention in 4 patients(44%), hematuria in 3 patients(33%), frequency in 2 patients(22%), G-I symptoms were also noticed in 4 patients(44%). 3. The histologic types were 6 rhabdomyosarcoma. 1 leiomyosarcoma, 1 liposarcoma and 1 lymphoma. 4. Among 2 cases in which metastasis was confirmed, lung and liver were the sites of metastasis in a prostate rhabdomyosarcoma and the cervical lymph node in a bladder lymphoma. 5. Four patients of 9 prostate and bladder sarcomas were treated with surgery and/or chemotherapy and/or radiotheraphy. Of these, 1 patient is alive 4 months since surgery to date, 2 patients died within l year and 1 patients is presumed dead.
Age Distribution ; Drug Therapy ; Dysuria ; Hematuria ; Humans ; Leiomyosarcoma ; Liposarcoma ; Liver ; Lung ; Lymph Nodes ; Lymphoma ; Neoplasm Metastasis ; Prognosis ; Prostate* ; Radiotherapy ; Retrospective Studies ; Rhabdomyosarcoma ; Sarcoma* ; Survival Rate ; Urinary Bladder* ; Urinary Retention

No abstract available.
Mass Screening* ; Uterine Cervical Neoplasms*

22 patients with proved urogenital malignancies was done to determine the value of bone scanning versus roentgenographic skeletal survey in assessing the degree of metastatic involvement with serum phosphatase level. Findings on bone scans were positive in 11 patients and in 6 patients of these patients results of radiologic of radiologic skeletal survey were negative. Of these 11 patients with positive scanning, 3 patients showed elevation of serum acid phosphatase and 4 other patients showed elevation of serum alkaline phosphatase. And of the others with negative scanning, 1 patient showed elevation of acid phosphatase and elevation of alkaline phosphatase in 3 other patients.
Acid Phosphatase ; Alkaline Phosphatase ; Diagnosis ; Humans ; Neoplasm Metastasis*

22 patients with proved urogenital malignancies was done to determine the value of bone scanning versus roentgenographic skeletal survey in assessing the degree of metastatic involvement with serum phosphatase level. Findings on bone scans were positive in 11 patients and in 6 patients of these patients results of radiologic of radiologic skeletal survey were negative. Of these 11 patients with positive scanning, 3 patients showed elevation of serum acid phosphatase and 4 other patients showed elevation of serum alkaline phosphatase. And of the others with negative scanning, 1 patient showed elevation of acid phosphatase and elevation of alkaline phosphatase in 3 other patients.
Acid Phosphatase ; Alkaline Phosphatase ; Diagnosis ; Humans ; Neoplasm Metastasis*

BACKGROUND: Most available dermatologic quality-of-life measures were written in English. So these must be translated for use in Korea. Our purpose was to translate and adapt culturally into Korean a skin-related quality-of-life measure Skindex-29, and to begin preliminary assessments of its reliability and validity. METHODS: Cross-cultural adaptation questionnaire studies were performed. Two hundred and sixty adult outpatients and healthy people responded to the Korean version of Skindex-29. Evaluations of the semantic equivalence of back-translated items, reliability, construct validity, and content validity of the Korean version were the main outcome measures. Comparison between the Korean version and other versions of Skindex-29 (Spanish and American) responses was also performed. RESULTS: Five problematic items required a second translation and back-translation to achieve satisfactory agreement with the original instrument. The final Korean version of Skindex-29 was internally reliable. The instrument demonstrated both construct and content validity. As hypothesized, scores for dermatologic patients were higher than those of healthy persons and scores for patients with inflammatory diseases were higher than those of persons with isolated skin lesions. Skindex scale scores of the Korean version and other versions of Skindex-29 were similar. CONCLUSIONS: We have developed a semantically equivalent translation of Skindex-29 in Korean. Our preliminary evaluation of its measurement properties suggests that it is a reliable and valid measure of the effects of skin disease on the quality of life in Korean patients.
Adult ; Male ; Female ; Humans

In our comparative study of L1 consensus primers with E6 type-specific primers for detection of human papillomavirus (HPVs) by polymerase chain reaction (PCR) in 35 cases of cervical neoplasia, the detection rate by E6 primers (54%; 19/35) was significantly higher than that by L1 primers (25%; 9/35) (p < 0.01). And all specimens HPV-positive with L1 primers were also positive by E6 primers. HPV DNA could be amplified in 36% (9 of 25) of tissue by L1 consensus primers from which beta-globin gene was amplified as compared with 64% (16 of 25) of tissue by E6 type-specific primers. With the L1 consensus primers, 8 cases were positive for HPV-16 and 1 case was positive for HPV-33. These results show that the L1 consensus primers have inferior sensitivity to the E6 type-specific primers for the detection of HPV by PCR. But the L1 consensus primers have great value in making simultaneous detection of various HPV types in a single tube reaction, thus they permit reduction of time and the economic burden of the experiment.
Base Sequence ; DNA, Viral/analysis ; Female ; Humans ; Molecular Sequence Data ; Oligodeoxyribonucleotides ; Papillomaviridae/genetics/*isolation & purification ; *Polymerase Chain Reaction ; Uterine Cervical Neoplasms/*microbiology

BACKGROUND: Although acne is extremely prevalent, few studies have focused on what the patient with acne vulgaris experiences. Furthermore, despite recent advances in the accurate measurement of health outcomes, few studies have discussed the influence of acne on discrete aspects of patients' experiences such as their quality of life. OBJECT: To determine the influence of acne vulgaris on the quality of life of adult dermatology outpatients, we performed cross-sectional and longitudinal questionnaire study. METHOD: Sixty patients with acne vulgaris attending appointments with their dermatologists. Findings using Skindex, a validated 29-item instrument to measure the effects of skin disease on patients' quality of life. Results are reported as 3 scale scores (functioning, emotions, and symptoms) and a composite score (average scale score). In addition, dermatologists rated the clinical severity of patients' skin disease. Higher Skindex scores indicate greater effects on quality of life. RESULTS: Patients with acne experienced functioning and emotional effects from their skin disease comparable with those of patients with psoriasis, but experienced fewer symptoms (for patients with acne and psoriasis, respectively, Skindex functioning scores of 14.9 and 22.8 [p=0.08]; emotion scores, 39.2 and 38.9 [p=0.95]; and symptoms scores, 29.5 and 42.1 [p<0.05]). Skindex scores were higher in older patients than in younger patients, and patients aged 40 years or older were less likely to report improvement in their acne after 3 months (43% vs 85%; p<0.05). Among patients reporting no improvement in their acne, older patients reported greater effects of their acne on their quality of life. Furthermore, in multivariate analyses, older adults reported more effects of acne on their quality of life than younger adults, even after controlling for sex and acne severity as judged by the dermatologist. CONCLUSIONS: Acne vulgaris significantly affects patients' quality of life. Sex, age, severity of acne and duration of acne can effect on quality of life of acne patients.
Acne Vulgaris* ; Adult ; Appointments and Schedules ; Dermatology ; Humans ; Multivariate Analysis ; Outpatients ; Psoriasis ; Quality of Life* ; Skin Diseases ; Surveys and Questionnaires