Yakovlev demonstrated that the Schizencephalies appear to result from injury to developing cerebral vesicles in the second month of intrauterine life. There is a total loss of neurons in restricted symmetrical zones of each developing hemisphere and on either side of the resulting cleft-shaped defects are evidences of subtotal injury to developing neuroblasts. A case of a 4 years old male with Schizencephaly is reported.
Child, Preschool ; Humans ; Male ; Malformations of Cortical Development* ; Neurons