2.Horizontal Tear of the Meniscus.
Sung Do CHO ; Dong Bae SHIN ; Yong Sun CHO ; Tae Woo PARK ; Young Kyu KIM
The Journal of the Korean Orthopaedic Association 1998;33(7):1737-1742
Horizontal tear of the meniscus occurs most commonly in older patients. The tear begins initially with a simple horizontal cleavage which divides the meniscus into superior and inferior leaves resembling a fish mouth and which may become a flap or more complex tear with time if subjected to repeated injury. Thirty-four patients(36knees/40menisci) with horizontal tear of the meniscus, treated with arthroscopic partial meniscectomy except in 3 extensive tears at Ulsan University Hospital from Jan. 1993 to Jun. 1996, were analyzed to investigate the factors that may be associated with this type of meniscal tear, and the results were as follows; 1. The tears commonly occurred in labor workers(61.7%) and without obvious trauma history(67.6%), and the average age at the time of surgery was 44 years. 2. The most common site of the tear was posterior horn of the medial meniscus (62.5%). 3. The 40 horizontal tears consisted of 12 horizontaVcleavage(30%), 3 horizontaVflap(7.5%), and 25 horizontaUdegenerative complex tears(62.5%). 4. Degenerative changes were frequently noted in both arthroscopy(69.5%) and roentgenography (72.2%).
Animals
;
Horns
;
Humans
;
Menisci, Tibial
;
Mouth
;
Radiography
;
Ulsan
3.Respiratory Syncytial Virus Infections and Application of Nested Reverse Transcription-Polymerase Chain Reaction.
Kon Hee LEE ; Hae Sun YOON ; Kyu Man KEE ; Kyung Hee KIM ; Yang ja CHO
Journal of the Korean Pediatric Society 1995;38(11):1486-1497
No abstract available.
Respiratory Syncytial Virus Infections*
;
Respiratory Syncytial Viruses*
4.A Case of Acute Transverse Myelitis Complicating Diffuse Spinal Cord Atrophy and Syrinx Formation.
Nam Cheol CHO ; Jin A JUNG ; Kyu Guen HWANG ; Sun Seob CHOI
Journal of the Korean Child Neurology Society 1997;5(1):167-171
A 4-year-old girl developed acute motor, sensory impairment, lower abdominal pain and urinary dysfunction after URI. In acute stage of disease, MRI showed diffuse spinal cord swelling and high signal intensity on T2WI below T2 body level. The patient did not improved and one month later, follow-up MRI showed diffuse spinal cord atrophy and syrinx formation as sequelae of ATM on T1WI below T9 level. To our knowledge, this is the first case showing the sequelae of acute transverse myelitis seen in Korea.
Abdominal Pain
;
Atrophy*
;
Child, Preschool
;
Female
;
Follow-Up Studies
;
Humans
;
Korea
;
Magnetic Resonance Imaging
;
Myelitis, Transverse*
;
Spinal Cord*
5.A Case of Primary Irritant Dermatitis due to Ranunculus Tachiorei.
Jung Woo SUN ; Si Yong KIM ; Young Cho KIM ; Kyu Chul CHOI ; Byound Soo CHUNG
Korean Journal of Dermatology 1999;37(10):1544-1547
Ranunculus tachiorei is a member of the buttercup family (Ranunculaceae) which contains unsaturated lactone and protoanemonine. Protoanemonine is formed by the breakdown of the glycoside Ranunculin after injury to the plant and causes severe vesiculation and linear streaks after contact with field buttercups(Ranunculus spp.) The amount of protoanemonine in buttercups varies widely with the species of plant and its stage of growth, the highest content being at the time of flowering. We report a case of primary irritant dermatitis due to contact with Ranunculus Tachiorei which was applied for the folk treatment of Bell palsy.
Bell Palsy
;
Dermatitis, Irritant*
;
Flowers
;
Humans
;
Plants
;
Ranunculus*
6.The Effect of Milk on the Bioavailability of 6-mercaptopurine.
Sun Kyu PARK ; Ran Ju KIM ; Pyoung Han HWANG ; Soo Chul CHO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1994;37(12):1732-1737
The purine antimetabolite 6-Mercaptopurine (6-MP) has been in clinical use for over 30 years and is still a widely used agent in the treatment of childhood acute lymphoblastic leukemia. The bioavailibility, clinical efficacy and toxicity of 6-MP administered orally for maintenance therapy of children with acute lymphoblastic leukemia are highly variable in many studies, as well as at differnt times in same patient. there are many factors affecting the bioavailibility of 6-MP. The most notably factor being that concomitantly administered drugs and foods might contribute to a decrease in the bioavailibity of this drug. In our sociocultural environment milk is a major constituent of child's foods. Cow's milk contains a high concentration of xanthine oxidase, which could potentially transform 6-TM into 6-thioxanthine (6-TX) and 6-thiouric acid (6-TUA) which have no more therapeutic effects. In this study, we evaluated the effect of various milk products on the bioavailability of 6-MP. Incubation at 37degrees C for 30 min raw or pasteurized milk resulted in transformation of a large quantity of clinically relevant concentration of 6-MP into 6-TUA. The concomitant adminstration of folic acid and allopurinol has markedly inhibitory effect on the 6-MP destroying activity of milk at clinically relevant concentrations. These observations may help to optimize modalities of administration of 6-MP for the treartment of patients with childhood leukemia.
6-Mercaptopurine*
;
Allopurinol
;
Biological Availability*
;
Child
;
Complement Factor B
;
Folic Acid
;
Humans
;
Leukemia
;
Milk*
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Xanthine Oxidase
7.Relation between Health Habits and Stree in Adolescents.
Journal of the Korean Academy of Family Medicine 1999;20(10):1247-1254
BACKGROUND: Adolesoents experience many physical, psychological and social stresses. It is well known that there is a strong relationship between stress and illness. It has been told that good health goes with good health habits. We examine the relationship between several health habits and stress in adolescents. METHODS: We surveyed adolescents and their parents who visited an adolescent clinic in a general hospital for 8 manths. Structured questionnaires about status of several health habits and BEPSI(The Brief Encounterr Psychosocial Instrument) score were used. BEPSI is a quick stress measure that is composed of several items. RESULTS: This study included 486 adolescents and their 486 parents. Average number of good health habits was 3.2+/-1.7 and average BEPSI score was 2.1+/-0.6. The group that had more good health habits tended to mark lower BEPSI scores(p<0.05). There was a significant relationship between stress and each habit except sleep time of more than 7hrs, regular exercise and hobby. Smoker group and alcohol drinker group showed higher BEPSI scores, respectively. The conversation time between parents and adolescents had a significant relationship with BEPSI scores. CONCLUSIONS: Several health habits were significantly connected with stress in adolescents. We can assume that good health habits and conversation with their parents are important in the management of stress in adolescents.
Adolescent*
;
Hobbies
;
Hospitals, General
;
Humans
;
Parents
;
Surveys and Questionnaires
8.Changes of serum igG4 in allergic patients.
Soo Young CHO ; Sun Kyu PARK ; Pyoung Han HWANG ; Jung Soo KIM
Journal of the Korean Pediatric Society 1993;36(3):403-408
This study was performed to evaluate the changes of serum IgG4 level in children with allergic diseases. Serum Ige, IgG and IgG4 level were measured using enyzme immunoassay (IgE) and radial immunodiffusion method (IgG and IgG4) in 21 children with bronchial asthma, allergic rhinitis or urticaria Eosinophil counts in peripheral blood and the values of serum IgE were significantly increased in allergic patients. The values of IgG4 in allergic patients were also increased compare to those in controls (24.23mg/dl versus 20.33mg/dl). But the values of IgG4 were not significantly correlated to either IgG or IgE levels. Further studies will be needed for measuring allergen specifie IgE and IgG4 levels considering the onset of diseases, methods and duration of treatment.
Asthma
;
Child
;
Eosinophils
;
Humans
;
Hypersensitivity
;
Immunoassay
;
Immunodiffusion
;
Immunoglobulin E
;
Immunoglobulin G*
;
Rhinitis
;
Urticaria
9.Changes of igG subclasses in the sera of the children with Kawasaki disease.
Seog Beom CHO ; Sun Kyu PARK ; Pyoung Han HWANG ; Jung Soo KIM ; Sa Hyoung CHOI
Journal of the Korean Pediatric Society 1993;36(9):1197-1202
Kawasaki disease is an acute vasculitis of infancy and early childhood characterized by high fever, rash, mucositis, lymphadenopathy and coronary artery damage. The failure to indentify a causative organism using convetional culture and serological techniques, and the lack of response to antibiotics indicate that the disorder is probably not due to any known bacterial or viral pathogens. During the acute phase of the disease, the alterations of T and B cell functions, changes of cytokine and immunoglobulin levels have been reported. This study was performed to investigate the changes of immunoglobulins levels in patients with Kawasaki disease. IgG, IgA, IgM and IgG subclasses were measured using immunoprecipitation and EIA in the sera of patients with Kawasaki disease. The results were as follows: 1) Acute phase reactants such as CRP and ESR were significantly increased in Kawasaki patients compared to those in control patients(p<0.01). 2) Serum IgG levels in Kawasaki disease were markedly increased than those in control patients, while serum IgA and IgM levels showed no significant changes (P: No Significance). 3) IgG1 and IgG4 were predominantly increased increased in the sera of Kawasaki patients, while IgG2 and IgG3 were not significantly increased (P: No Significance). With these results, unidentified infectious organism with abnormal immune response could be suggested as an etiologic factor of Kawasaki disease.
Acute-Phase Proteins
;
Anti-Bacterial Agents
;
Child*
;
Coronary Vessels
;
Exanthema
;
Fever
;
Humans
;
Immunoglobulin A
;
Immunoglobulin G*
;
Immunoglobulin M
;
Immunoglobulins
;
Immunoprecipitation
;
Lymphatic Diseases
;
Mucocutaneous Lymph Node Syndrome*
;
Mucositis
;
Vasculitis
10.The effect of craterellus aureus extracts to proliferation ofsarcoma-180 cells.
Mi Kyung CHO ; Kyu Sun JUNG ; Chul Hee PARK ; Yun Tai LEE
Korean Journal of Immunology 1991;13(2):215-224
No abstract available.