1.Effects of preconditioning against reperfusion injury in rat skeletal muscle.
Kyu Jeong HAN ; Chang Sub UHM ; Dong Ho KIM ; Young Suk SUH
Korean Journal of Anatomy 1993;26(2):199-213
No abstract available.
Animals
;
Muscle, Skeletal*
;
Rats*
;
Reperfusion Injury*
;
Reperfusion*
2.A Case of Corrected Transposition of Great Vessels, Associated with itral?Insufficiency.
Jae Wha CHOI ; Ki Sub SHIN ; Kyung Tai WHANG ; Kyong Su LEE ; Han Kyu PARK ; Kyung Sub SHINN
Journal of the Korean Pediatric Society 1977;20(10):757-762
Congentally corrected transposition of the great vessels can best be defined as a malformation in which the aorta and pulmonary artery are transposed in relation to each other but in which the flow of blood is in the physiologic direction. And in addition to the malposition of great vessels, there is an inversion of the ventrice,. Unfortunately this basic malformation seldom exists withot complicating cardiovascular anomalies. We had experienced a case of congenitally corrected transposition of the great vessels associated with itral?insufficiency in 13year-old boy, who presented the most above mentioned findings. We have made diagnosis by cardiac catheterization and selective angiocardiographic study.
Aorta
;
Cardiac Catheterization
;
Cardiac Catheters
;
Diagnosis
;
Humans
;
Male
;
Pulmonary Artery
;
Transposition of Great Vessels*
3.MRI Evaluation of the Vascular Pattern in Intracranial Meningioma.
Mi Hye KIM ; Kyung Sub SHINN ; Hyo Sun CHOI ; Kyu Ho CHOI ; Il Gwon YANG ; Han Jin LEE
Journal of the Korean Radiological Society 1994;30(2):225-229
PURPOSE: The purpose of this study was to assess the usefulness of MRI in the evaluation of vascular changes of the meningioma. MATERIALS AND METHODS: We retrospectively studied the MRI findings in 20 cases of intracranial meningiomas. The images were assessed for vascular hilum, vascular rim, sinus invasion, and vascular encasement. Cerebral angiograms were obtained in 15 cases and compared with MRI findings. RESULTS: MRI was as accurate as angiography in detection of vascular hilum(MRl=8/20, Anglogram=9/15), vascular rim(MRl=14/20, Angiogram=9/15) and dural sinus invasion(MRl=4/6, Angiogram=5/6). MRI was superior to angiography in detection of vascular encasement(MRl=2/3, Angiogram=0/2) and cavernous sinus invasion(MRI=3/3, Angiogram=0/2). CONCLUSION: MRI is an excellent noninvasive imaging modality in evaluating vascular changes of omas.
Angiography
;
Cavernous Sinus
;
Magnetic Resonance Imaging*
;
Meningioma
;
Retrospective Studies
4.Identification of Streptococcus viridans group Isolated from the Blood of Patients.
Jongyoun YI ; Byoung Wook SONG ; Kyu LEE ; Kyu Sub HAN ; Myoung Hee PARK ; Eui Chong KIM
Korean Journal of Clinical Microbiology 2003;6(1):12-17
BACKGROUND: Streptococcus viridans group (SVG) is the normal flora of the upper respiratory tract, skin and genitourinary tract, and is the major causative agent isolated in 30-40% of bacterial endocarditis patients. However, SVG has not been properly identified to the species level for lack of diagnostic system which enables the accurate identification of SVG. Poyart et al. have recently described the identification of SVG to the species level by DNA sequencing of superoxide dismutase gene (sodAint). Using this method, we report here the identification of SVG isolated from the patients in Seoul National University Hospital within recent 2 years. METHODS: According to the method by Poyart et al., a set of two oligonucleotides, D1 (5 '-CCI TAY ICI TAY GAY GCI YTI GAR CC-3 ') and D2 (5 '-ARR TAR TAI GCR TGY TCC CAI ACR TC-3 ') were used as PCR primers, and PCR products of 480-bp size were obtained. The PCR products purified by MicroSpin S-400 HR Column were sequenced using ABI-PRISM 3700 Sequence Analyzer. D1 and D2 were used as sequencing primers. The clinical isolates were respectively identified as the species showing the greatest sequence homology which was demonstrated by the BLAST program provided by NCBI(USA). RESULTS: Clinical strains isolated from 26 patients who had shown two or more positive blood cultures were analyzed by DNA sequencing of superoxide dismutase gene, which showed 6 strains of S. salivarius, five S. oralis, four S. sanguis, three S. pasteuri, three S. equisimilis, two S. gordonii, one S. constellatus, one S. luteciae, and one S. mitis. S. salivarius and S. sanguis were clearly discriminated, while S. equisimilis and S. pyogenes were not. Species identification results by conventional method seldom corresponded to those by DNA sequencing. Among 7 patients suspected to have bacterial endocarditis, S. sanguis were isolated in 4 patients, and S. gordonii, S. oralis, S. pasteuri in one, respectively. Among 17 patients with liver cirrhosis or cancer, S. salivarius were isolated in 6 patients, and S. oralis in four. CONCLUSIONS: In this study, we could identify the species of SVG isolated from the patients with bacteremia; S. sanguis were frequently isolated from patients with bacterial endocarditis, while S. salivarius from ones with malignancy. These results imply that a different group of underlying diseases could show correspondingly different group of SVG species which cause bacteremia, and we suggest that further pathophysiological study on the correlations between underlying disease and the species of SVG be performed.
Bacteremia
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Endocarditis, Bacterial
;
Homosexuality, Male
;
Humans
;
Liver Cirrhosis
;
Male
;
Oligonucleotides
;
Polymerase Chain Reaction
;
Respiratory System
;
Seoul
;
Sequence Analysis
;
Sequence Analysis, DNA
;
Sequence Homology
;
Skin
;
Streptococcus*
;
Superoxide Dismutase
;
Viridans Streptococci*
5.A Case of Infantile Polycystic Kidney confirmed by C-T Scan.
Kwan Sub CHUNG ; Soo Hyung KIM ; Deng Gwan HAN ; Pyung Kil KIM ; Kyu Ok CHOE
Journal of the Korean Pediatric Society 1979;22(8):744-751
A case of infantile polycystic kindney disease confirmed by computerired tomoraphy in a newborn female infant was reported with a brief review of references.
Female
;
Humans
;
Infant
;
Infant, Newborn
;
Polycystic Kidney Diseases*
6.Clinical Observation of the Comatose Patiente in the Postoperative Period .
Han Sik SUH ; Hyo Jong BAIK ; Inn Se KIM ; Kyu Sub CHUNG
Korean Journal of Anesthesiology 1981;14(4):472-476
The etiology of postoperative unconsciousness is p is various in origin. From Jan. 1973 to May 1981, 14 unconscious patients via the emergency room were treated in the intensive care unit at Pusan National University Hospital. The results are summarized as follows: 1) Sex distribution was 5 males and 9 males, and the age distribution was from 7 to 54. 2) The type of surgery were mainly hystrectomy and oophorectomy(6 cases) and the others were appendectomy(4 cases), gastrectomy(1 case), Cholecystectomy(1 case), and anal fistulectomy( 1case). 3) Seven cases were performed under spinal anesthesia, 6 cases were under inhalation anesthesia, and 1 case was done under Ketamine Hcl intravenous anesthesia. 4) On arrival at ICU, 12 patients were fully comatose and the others were semicomatese. 5) Meperidine was injected in 4 cases for the purpose of postoperative pain relief. 6) Ten cases expired, 3 cases recovered and 1 case was discharged without hope.
Age Distribution
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Anesthesia, Inhalation
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Anesthesia, Intravenous
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Anesthesia, Spinal
;
Busan
;
Coma*
;
Emergency Service, Hospital
;
Hope
;
Humans
;
Intensive Care Units
;
Ketamine
;
Male
;
Meperidine
;
Pain, Postoperative
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Postoperative Period*
;
Sex Distribution
;
Unconsciousness
7.General Anesthetic Experience for Removal of Trscheobronchesl Foreign Bodies .
Nak Seon KIM ; Han Sik SUH ; Kyu Sub CHUNG ; Suk Hee LEE
Korean Journal of Anesthesiology 1980;13(4):350-354
The authors analyzed a total of 49 cases of general anesthesia for the removal of tracheo bronchial foreign bodies, from Jan. 1970 to Aug. 1980. The results were as follows; 1) Sex distribution was 36 males(73.5%) and 13 females(26.5%). 2) Age distribution was 14 cases under 1 year and also 14 of 1-3 year olds(total 57. 2%). 3) Anesthetic agents were halothane, 32 cases(65.3%), diethyl ether, 9 cases(18.4%) and others. 4) The kinds of foreign bodies were peanuts in 24 cases(49.0%) and the others were various. 5) The sites of foreign bodies were Rt. main bronchus 29 cases(59. 2%), Lt. main bronchus in 12 cases of(24.5%), trachea 7 cases(14.3%) and vocal-cord 1 case(2.0%). 6) Anesthetic duration was within 1 hour, 41 cases(83. 7%). 7) Complications during operation were tachycardia in 36 cases. 8) Postoperative pulmonary complications were pneumonia, 4 cases and 1 case each of pyothorax, atelectasis and death.
Age Distribution
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Anesthesia, General
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Anesthetics
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Arachis
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Bronchi
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Empyema, Pleural
;
Ether
;
Foreign Bodies*
;
Halothane
;
Pneumonia
;
Pulmonary Atelectasis
;
Sex Distribution
;
Tachycardia
;
Trachea
8.Radiologic Features of Posterior Fossa Hemangioblastomas: Emphasis on MR Findings.
Kyung Sub SHINN ; Kyu Ho CHOI ; Seong Tae HAHN ; Choon Yul KIM ; Han Jin LEE ; Seon Kyo KIM ; Myung Hee JEONG
Journal of the Korean Radiological Society 1995;32(3):397-403
PURPOSE: To review MR findings of the posterior fossa hemangioblastomas and to evaluate diagnostic value of MRI correlated with CT and anglographic findings. MATERIALS AND METHODS: The MR findings in twelve patients with surgically proven posterior fossa hemangioblastomas including one case of von Hippel- Lindau disease were retrospectively analyzed and correlated with CT (7 patients) and anglographic findings (9 patients). RESULTS: On MRI, five hemangioblastomas were located in the cerebellar hemisphere and seven in the vermis. The masses appeared to be solid in 3 cases(25%), solid tumors with central cyst in 2 cases(17%), and cyst with mural nodules in 7 cases(58%). Abnormal tumor vessels represented by characteristic signal voids on MRI were observed in 9 cases(75%) and were not seen in 3 cases(25%) with mural nodule below 1.5cm in diameter. On pre-contrast CT, hemangioblastomas appeared poorly marginated slightly hyperdense masses in solid tumors, and hypodense cystic masses in cysts. After contrast enhancement, solid tumors were markedly enhanced, but it was difficult to differentiate hemangioblastomas from other tumors. In nine patients, anglograms demonstrated hypervascular blush corresponding to the solid component of the tumors. CONCLUSION: MRI was superior to CT in evaluating the characteristic of abnormal tumor vessels and mural nodules, delineation of tumor margin and tumor extent. Angiography was useful in the diagnosis of cystic hemangioblastomas which contain small mural nodule (less than 1.5cm in diameter) without definite vascular signal voids on MRI. MRI demonstrated solid or cystic tumor with small mural nodule and abnormal vascular signal voids in the posterior fossa should suggest hemangioblastoma.
Angiography
;
Diagnosis
;
Hemangioblastoma*
;
Humans
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
von Hippel-Lindau Disease
9.CT and MRI Findings of Malignant Meningiomas: Comparison with Benign Meningiomas.
Il Kwon YANG ; Kyung Sub SHINN ; Myung Hee CHUNG ; Kyu Ho CHOI ; Han Jin LEE ; Seon Ok JEONG ; Seon Kyo KIM ; Jeong Soo JEON
Journal of the Korean Radiological Society 1995;32(3):375-381
PURPOSE: The purpose is to evaluate the CT or MRI findings to help in the differentiation between benign and malignant meningiomas. MATERIAL AND METHODS: The CT and MRI findings of 8 patients with surgically proven malignant meningioma were reviewed. Four cases of 8 malignant meningiomas and 18 cases of 27 benign lesions were studied with a 1.5T or 0.5T MRI. Radiologic analysis was focused on the heterogeneity of tumor, grade of peritumoral edema, presence of cystic degeneration and calcification, tumoral enhancement pattern, dural enhancement, and tumoral border. RESULT: Histologic types of malignant meningioma were meningotheliomatous (n=4), papillary(n=1), fibroblastic(n=l), angioblastic(n=l), and sarcomatous(n=l). Tumoral Heterogeneity was seen in 8 of 8 malignant lesions(100%) and 8 of 27 benign ones(30%). (p<0.01) Marked peritumoral edema was seen in 8 of 8 malignant lesions(100%) and 2 of 27 benign ones. (7.3%)(p<0.01) Most of malignant lesions(6 of 8 cases, 75%) showed ill defined border. Calcification was not present in malignant lesions in contrast with benign ones (14 of 27 cases, 52%). (p<0.05) No statistical significance was noted in cystic degeneration, dural tail like enhancement or tumoral enhancement pattern between malignant and benign meningiomas. MRI signal intensity of malignant meningiomas was homogeneously or heterogeneously hypointense on T1WI, heterogeneously isointense or hypointense on T2WI and heterogeneous or mixed on Gd-DTPA enhancement study. CONCLUSION: The CT or MRI findings such as heterogeneity, ill defined tumoral border, marked peritumoral edema, and absence of calcification may suggest the possibility of malignancy in meningioma.
Edema
;
Gadolinium DTPA
;
Humans
;
Magnetic Resonance Imaging*
;
Meningioma*
;
Population Characteristics
10.CT Findings of Spontaneous Subarachnoid Hemorrhage of Unknown Cause.
Il Kwon YANG ; Kyung Sub SHINN ; Hee Jeong RO ; Myung Hee CHUNG ; Kyu Ho CHOI ; Han Jin LEE ; Seog Min PARK ; Taek Geun KIM
Journal of the Korean Radiological Society 1994;30(3):401-404
PURPOSE: Spontaneous subarachnoid hemorrhage(S-SAH) is a relatively rare disease with good clinical course and prognosis. The purpose of this study is to evaluate the cisternal blood distribution on CT in patient with S-SAH. MATERIALS AND METHODS: Out of 406 patients with subarachnoid hemorrhage on brain CT scan, 11 patients confirmed to be S-SAH by angiography and clinical follow-up were examined. We analysed the CT findings of these 11 cases retrospectively. RESULTS: Five patients had only perimesencephalic distribution of hemorrhage:the prepontine, the interped- uncular, and the suprasellar cisterns were involved in 4 cases each, the basal sylvian cistern in 3 cases, and the ambient cistern in 2 cases. The quadrigeminal and a portion of the lateral sylvians were also involved in 1 case each. Six patients revealed cisternal hemorrhage extending beyond the perimesencephalic cistern into the ventricles, cortical sulci, and lateral sylvian fissure. Intraventricular hemorrhage was noted in 3 cases of these 6 patients. CONCLUSION: Our study suggests that uncomplicated clinical course and normal anglographic finding are more important than CT distribution of cisternal hemorrhage in diagnosing S-SAH.
Angiography
;
Brain
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Prognosis
;
Rare Diseases
;
Retrospective Studies
;
Subarachnoid Hemorrhage*
;
Tomography, X-Ray Computed