1.High Cardiac Output Heart Failure Induced by Chronic Severe Anemia.
Seung In SEO ; Dae Gyun PARK ; Min Kwan KIM ; Sung Eun KIM ; Jun Hee LEE ; Kyu Rock HAN ; Dong Jin OH
Korean Journal of Medicine 2011;81(3):378-381
High cardiac output heart failure (HCOHF) occurs in the setting of increased cardiac output, such as with chronic anemia, hyperthyroidism, beriberi, pregnancy, and an arteriovenous (AV) fistula. Of these, chronic anemia is a rare cause of HCOHF and its pathophysiology remains unknown. This report is about a patient with chronic anemia who presented with heart failure and severe tricuspid regurgitation. The severity of the tricuspid regurgitation and the patient's symptoms and signs were improved on correcting the anemia.
Anemia
;
Beriberi
;
Cardiac Output
;
Cardiac Output, High
;
Fistula
;
Heart
;
Heart Failure
;
Humans
;
Hyperthyroidism
;
Pregnancy
;
Tricuspid Valve Insufficiency
2.Effects of Radiofrequency Induced local Hyperthermia on Normal Canine Liver.
Chang Ok SUH ; John Juhn Kyu LOH ; Jin Sil SUNG ; Sun Rock MOON ; Hyung Sik LEE ; Hyun Soo SHIN ; Sung Sil CHU ; Gwi Eon KIM ; Chan Il PARK ; Eun Kyung HAN
Journal of the Korean Society for Therapeutic Radiology 1991;9(1):37-46
In order to assess the effects of radiofrequency-induced local hyperthermia on the normal liver, histopathologic findings and biochemical changes after localized hyperthemia in canine liver were studied. Hyperthermia was externally administered using the Thermotron RF-8 (Yamamoto Vinyter Co., Japan; Capacitive type heating machine) with parallel opposed electrodes. Thirteen dogs were used and allocated into one control group (N=3) and two treatment groups according to the treatment temperature. GroupI(N=5) was heated with 42.5+/-0.5degree C for 30 minutes, and GroupII(N=5) was heated with 45+/-0.5degree C for 15-30 minutes. Samples of liver tissue were obtained through a needle biopsy immediately afterhyperthermia and 7, 14 and 28 days after treatment and examined for SGOT, SGPT and alkaline phosphatase. Although SGOT and SGPT were elevated after hyperthermia in both groups (three of five in each group), there was no liver cell necrosis or hyperthermia related mortality in GroupI. A hydropic swelling of hepatocytes was prominent histologic finding. Hyperthermia with 45degree C for 30 minutes was fatal and showed extensive liver cell necrosis. In conclusion, liver damage day heat of 42.5+/-0.5degree C for 30 minutes is reversible, and liver damage by heat of 45+/-0.5degree C for 30 minutes can be fatal or irreversible. However, these results cannot be applied directly to human trial. Therefore, in order to apply hyperthermic treatment on human liver tumor safely, close observation of temperature with proper thermometry is mandatory. Hyperthermic treatment should be confined to the tumor area while sparing a normal liver as much as possible.
Alanine Transaminase
;
Alkaline Phosphatase
;
Animals
;
Aspartate Aminotransferases
;
Biopsy, Needle
;
Dogs
;
Electrodes
;
Fever
;
Heating
;
Hepatocytes
;
Hot Temperature
;
Humans
;
Hyperthermia, Induced*
;
Japan
;
Liver*
;
Mortality
;
Necrosis
;
Thermometry
3.Monitoring System during Enflurane Anesthesia Using Heart Rate Variability.
Seong Wan BAIK ; Kyu Youn JUNG ; Soo Young YE ; Bong Hyo HAN ; Byeong Cheol CHOI ; Gye Rock JEON
Korean Journal of Anesthesiology 2004;46(2):175-179
BACKGROUND:We performed spectral analysis and determined the 1/f noise of heart rate variability during enflurane anaesthesia in order to assess the effect of the activity of the autonomic nervous system. METHODS: Data were acquired from 15 patients (ASA I-II) who received gynecological surgery under general anesthesia using enflurane, nitrous oxide and oxygen. We analyzed the spectral components of heart rate variability (HRV) according to the following five periods: 1) before premedication, 2) after induction, 3) during skin incision, 4) during recovery, and 5) after surgery. For each power spectrum the density and frequency components were identified as follows: (1) low frequency (LF) component (0.04-0.15 Hz) was associated with parasympathetic and sympathetic tone, and was affected by body temperature, the renin-angiotensin system, baroreceptor and vasomotor sympathetic modulation, (2) high frequency (HF) component (0.15-0.5 Hz) was mediated parasympathetic tone and reflected the mechanical influence of the ventilation. In addition the LF/HF ratio, which reflected cardiac sympathovagal balance was monitored. RESULTS: The LF/HF ratio, which reflects the balance of the autonomic nervous system increased remarkably during skin incision and recovery. Also, the beta index, which is related to body activity decreased during skin incision and recovery. CONCLUSIONS: Increased LF/HF was found to be caused by mechanical stimulation, which reflects autonomic nervous system balance, and the beta index was useful for the assessment of body activity.
Anesthesia*
;
Anesthesia, General
;
Autonomic Nervous System
;
Body Temperature
;
Enflurane*
;
Female
;
Gynecologic Surgical Procedures
;
Heart Rate*
;
Heart*
;
Humans
;
Nitrous Oxide
;
Noise
;
Oxygen
;
Premedication
;
Pressoreceptors
;
Renin-Angiotensin System
;
Skin
;
Ventilation