No abstract available.
Clothing* ; Dermatitis, Allergic Contact* ; Nickel*

Primary malignant melanoma of tbe esophagus is extremely rare and its incidence is below 0.1%. The tumor is polypoid and tend to be large, which is covered with false membrane, friable, hemorrhagic, and necrotic. Hematogenous and lymphogenic metastasis are common. Resection of the tumor with an anastomotic procedure seems to be the treatment of choice, and postoperative irradiation may be useful. But, despite these measures, prognosis is poor, with a 5-year survival of 4.2%. We report a case of 58-year-old man with primary malig- nant melanoma of the epophagus, and review of the literature in presented related studies.
Esophagus* ; Humans ; Incidence ; Intestines* ; Melanoma* ; Membranes ; Middle Aged ; Neoplasm Metastasis ; Prognosis ; Stomach*

No abstract available.
Abscess* ; Injections, Intramuscular* ; Pseudomonas aeruginosa* ; Pseudomonas*

PURPOSE: There is no standard targeted therapy for the treatment of triple-negative breast cancer (TNBC). Therefore, its management heavily depends on adjuvant chemotherapy. Using core needle biopsy, this study evaluated the histological factors of TNBC predicting the response to chemotherapy. METHODS: One hundred forty-three TNBC patients who received single-regimen neoadjuvant chemotherapy (NAC) with the combination of doxorubicin, cyclophosphamide, and docetaxel were enrolled. The core needle biopsy specimens acquired before NAC were used to analyze the clinicopathologic variables and overall performance of the predictive model for therapeutic response. RESULTS: Independent predictors of pathologic complete response after NAC were found to be higher number of tumor infiltrating lymphocytes (p=0.007), absence of clear cytoplasm (p=0.008), low necrosis (p=0.018), and high histologic grade (p=0.039). In the receiver operating characteristics curve analysis, the area under curve for the combination of these four variables was 0.777. CONCLUSION: The present study demonstrated that a predictive model using the above four variables can predict therapeutic response to single-regimen NAC with the combination of doxorubicin, cyclophosphamide, and docetaxel in TNBC. Therefore, adding these morphologic variables to clinical and genomic signatures might enhance the ability to predict the therapeutic response to NAC in TNBC.
Area Under Curve ; Biopsy, Large-Core Needle ; Chemotherapy, Adjuvant ; Cyclophosphamide ; Cytoplasm ; Doxorubicin ; Drug Therapy* ; Humans ; Lymphocytes, Tumor-Infiltrating ; Necrosis ; Neoadjuvant Therapy ; ROC Curve ; Treatment Outcome ; Triple Negative Breast Neoplasms*

No abstract available.
Adult* ; Humans

No abstract available.
Adult* ; Humans

BACKGROUND/AIMS: Ecabet sodium is used for treating gastric ulcers and gastritis. It exhibits a bactericidal effect against Helicobacter pylori by inhibiting bacterial urease activity. Thus, ecabet sodium has been suggested to improve the efficacy of the H. pylori eradication in patients with peptic ulcers. The aim of this study was to compare the H. pylori eradication rate of lansoprazole-based triple therapy versus lansoprazole-based triple therapy plus ecabet sodium. METHODS: The subjects consisted of 363 H. pylori-positive patients who had undergone eradication therapy from February 2007 to February 2010. In total, 363 patients with H. pylori-positive peptic ulcer disease or symptomatic erosive gastritis received LAC (lansprazole 30 mg b.i.d., amoxicillin 1.0 g b.i.d., clarithromycin 500 mg b.i.d.) or LACE (lansoprazole 30 mg b.i.d., amoxicillin 1.0 g b.i.d., clarithromycin 500 mg b.i.d., ecabet sodium 1 g b.i.d.) for 1 week. Successful eradication was defined as a negative 13Curea breath test 4-5 weeks after treatment completion. RESULTS: H. pylori eradication rates were 81.4% (166/204) in the LAC group and 86.2% (137/159) in the LACE group (p = 0.159). No significant difference in eradication was observed. No significant difference was observed in the side effects experienced by the patients in the two treatment groups. CONCLUSIONS: Our results suggest that adding ecabet sodium did not improve the H. pylori eradication rate significantly in standard lansoprazole-based triple therapy for H. pylori.
Amoxicillin ; Breath Tests ; Clarithromycin ; Diterpenes, Abietane ; Gastritis ; Helicobacter ; Helicobacter pylori ; Humans ; Peptic Ulcer ; Prospective Studies ; Sodium ; Stomach Ulcer ; Urease

Placenta increta is a kind of placental adhesion which can cause severe postpartum hemorrhage and life-threatening condition. It might necessitate a hysterectomy, but conservative management can be considerable for preserving reproductive potential when possible. A 34-years-old woman in her 41st week of pregnancy had normal full term spontaneous delivery. Retained placenta after removal by placenta forceps resulted in mild bleeding. Placenta increta was clinically diagnosed on computerized tomography. Remnant placenta in situ was nearly disappeared 2 months later after five-time intramuscular injection of 50 mg methotrexate and three-times curettage was done for conservative management.
Curettage ; Female ; Hemorrhage ; Humans ; Hysterectomy ; Injections, Intramuscular ; Methotrexate ; Placenta ; Placenta Accreta ; Placenta, Retained ; Postpartum Hemorrhage ; Pregnancy ; Surgical Instruments

PURPOSE: This study was to investigate the effects of U-Health program on metabolic syndrome of workers. METHODS: This study was conducted with a pretest-posttest control group study for 6 month from May to October 2010. Subjects in the experimental group participated in the U-Health program (n=315), whereas the control group did not (n=157). RESULTS: In the U-Health group, statistically significant reductions in BMI(body mass index), waist circumference, cholesterol, and triglyceride were observed. The results of this study showed that 6 months of U-Health program influenced on the metabolic syndrome of workers in a positive way. CONCLUSION: It is, therefore, suggested to actively utilize the U-Health program to manage the workers' health.

PURPOSE: This study was to investigate the effects of U-Health program on metabolic syndrome of workers. METHODS: This study was conducted with a pretest-posttest control group study for 6 month from May to October 2010. Subjects in the experimental group participated in the U-Health program (n=315), whereas the control group did not (n=157). RESULTS: In the U-Health group, statistically significant reductions in BMI(body mass index), waist circumference, cholesterol, and triglyceride were observed. The results of this study showed that 6 months of U-Health program influenced on the metabolic syndrome of workers in a positive way. CONCLUSION: It is, therefore, suggested to actively utilize the U-Health program to manage the workers' health.