1.Variations of the Transposition Flap for Facial Reconstruction after Mohs Micrographic Surgery of the Basal Cell Carcinoma.
Annals of Dermatology 1995;7(2):134-137
BACKGROUND: The transposition flap is one of the most useful methods of facial reconstruction after Mohs micrographic surgery of the basal cell carcinoma, but occasionally some variations are needed. OBJECTIVE: We present our experience with several variations of the transposition flap to overcome the disadvantages of classic rhomboid flaps. METHODS: We performed the Webster 30-degree angle flap on the lower eyelid, the double 30-degree angle flap on the temple area and the nasolabial flap on the ala nasi. RESULTS: These variations of the transposition flap gave no complications such as ectropion, tissue distortion, protrusion, or trapdoor deformity. CONCLUSION: The variations of the transposition flap in our cases might be of help in selecting the ideal method in facial reconstruction.
Carcinoma, Basal Cell*
;
Congenital Abnormalities
;
Ectropion
;
Eyelids
;
Methods
;
Mohs Surgery*
2.Monoclonal Antibodies Specific for Treponema Pallidum , Nichols Strain.
Min Geol LEE ; Kyu Kwang HWANG ; Jung Bock LEE
Korean Journal of Dermatology 1990;28(6):686-701
No abstract available.
Antibodies, Monoclonal*
;
Treponema pallidum*
;
Treponema*
3.Reactivity of the 19S ( IgM ) - FTA Test Among the Sera from VDRL Reactive Patients without History of Syphilitic Symptoms or Treatment.
Kyu Kwang WHANG ; Min Geol LEE ; Jung Bock LEE
Korean Journal of Dermatology 1987;25(3):355-360
On a total 233 sera from the VDRL reactive patients without a history of syphilitic symptoms or treatment for syphilis, TPHA and 19S(IgM)-FTA tests were performed, Also the reactivities of the 19 S (IgM)-FTA test in relation to the VDRL and the TPHA titers were observed. The results are summarized as follows: 1. Among 233 sera, 103 sera(44%) showed negative results in the 19S(IgM)- FTA test. 2. Reactivities of the 19 S(IgM)-FTA test were significantly increased in relation to the VDRL, titers arnong 233 sera reactive in the VDRL test: 47% in the VDRL titer 1: 1, 61% in 1: 2, 71% in 1: 4, 62% in 1: 8, 96% 1: 16 or more. 3. There was no relationship statistically (IgM)-FTA test and the TPHA titers. It can be derived from the above results that when a person with no history of treatment for syphilis and clear of any signs of syphilis shows a positive reaction in the VDRL test, he is less likey to be a syphilis patient when the VDRL titer is low.
Humans
;
Immunoglobulin M*
;
Syphilis
4.Biologic Significance of Hepatocyte Hepatitis B Core Antigen Expression in Chronic Hepatitis B Virus Infection II.
Hye Kyung LEE ; Kwang Min LEE ; Dong Kyu CHUNG
Korean Journal of Pathology 1992;26(4):355-359
Routine use of commercially available antisera against hepatitis B core antigen(HBcAg) has permitted a reevaluation of the histochemical distribution of the antigen in liver tissue. HBcAg, classically described almost exclusively in the nucleus, was found with a very high frequency in the cytoplasm of liver cells as well. To elucidate the biologic significance of HBcAg expression and its relation to the natural course of hepatitis B virus(HBV) infection, the patterns of activity in 33 needle liver biopsies of HBsAg carriers were analysed. A good correlation of liver HBcAg with disease activity was demonstrated. HBcAg was present in the hepatocyte nuclei(nHBcAg) or cytoplasm(cHBcAg), or in both(mixed). Pure nHBcAg was seen mainly in non-aggressive reactive liver tissue and cHBcAg was predominantly associated with chronic active hepatitis(95%). The results suggest that expression of HBcAg correlates with the liver pathology and the possibility of HBcAg to be an immunological target for T cell mediated hepatocyte damage.
Biopsy
5.Retrospective Study on the Clinical Features of Ota's Nevus.
Min Jae LEE ; Kyu Kwang WHANG ; Ki Bum MYUNG
Korean Journal of Dermatology 1995;33(3):430-436
BACKGROUND: Ota's nevus is not an uncommon pigmenta y disorder in Asian people including Koreans. OBJECTIVE: The purpose of this study was to examine the clinical features of the patients and to determine the existince of any relevance between them. METHODS: We arrid out a retrospective study with cialreviews and phone interviews or direct examinatior. for clinical features of the lesions in acesible patients. RESULTS: The peak age of onset was at birth, pubertyed adolescence in decreasing order. The most frequen1,ly involved site was the eyelid, and the type I was the most common. Bluish black color was pie edorninant. The lesions which did not inili the eyelid or the lesions which developed after birtten were more likely to be light brown in cilc(p<0.05). CONCLUSION: The clrical features of Otas nevus were revwed and analyzed statistically.
Adolescent
;
Age of Onset
;
Asian Continental Ancestry Group
;
Eyelids
;
Humans
;
Nevus of Ota*
;
Parturition
;
Retrospective Studies*
6.Serum Levels of ICAM-1(In tercelluar Adhesion Molecule-1) in Invasive Cervical Cancer.
Yong Min KIM ; Yoon Jung CHO ; Kyu Wan LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(3):258-263
ICAM-l(Intercellular adhesion molecule-1) is an important early marker of immune activation and response. ICAM-1 is expressed on varous cell types and observed in a variety of diseases, including patients with asthma, melanoma, prostatic cancer, ovarian and colon cancer. Some authors demonstrated the expression of ICAM-1 protein in high-grade intraepithelial squamous neoplasia of cervix by immunohistochemistry and suggested that the expression was related to human papillomavirus infection. The aim of this study was to determine the serum levels of soluble intercellular adhesion molecule-1(sICAM-1) in patients with squamous cell carcinoma of the cervix, Serum levels of sICAM-1 were measured by enzyme-linked immunosorbent assay(ELISA), We evaluate invasive squamous cell carcinoma of the cervix (40), carcinoma in situ (16) and control (15) patients. Serum levels of sICAM-1 in healthy volunteers, in parients with carcinoma in situ and invasive cervical cancer were 150.1+/-41.3, 182.7+/-105.9, 189.8+/-60.0 ng/ml, respectively. Although the serum levels of sICAM-1 in patients with carcinoma in situ did not increase, serum levels of ICAM-1 in patients with invasive cervical cancer were significantly increased (control vs invasive cervical cancer, p < 0,05). From the above results, sICAM-1 is shed from the cancerous tissue in patients with squamous cell carcinoma of the cervix.
Asthma
;
Carcinoma in Situ
;
Carcinoma, Squamous Cell
;
Cervix Uteri
;
Colonic Neoplasms
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Healthy Volunteers
;
Humans
;
Immunohistochemistry
;
Intercellular Adhesion Molecule-1
;
Melanoma
;
Papillomavirus Infections
;
Prostatic Neoplasms
;
Uterine Cervical Neoplasms*
7.The analysis of risk factors influencing lymph node metastasis in invasive carcinoma of the cervix.
Hyung Min CHOI ; Tchan Kyu PARK ; Kwang Kil LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):2214-2219
No abstract available.
Cervix Uteri*
;
Female
;
Lymph Nodes*
;
Neoplasm Metastasis*
;
Risk Factors*
8.A Clinical Observation of Cutaneous Manifestations in Patients with Viral Hepatitis according to Serotype.
Min Kyu CHO ; Kwang Joong KIM ; Chong Ju LEE
Korean Journal of Dermatology 1998;36(3):430-440
BACKGROUND: Specified clinical observations regarding skin changes in viral hepatitis have not yet been accomplished in Korea, especially in view of serotypes. OBJECTIVE: This study was conducted to identify various cutaneous manifestations of viral hepatitis according to viral serotypes and the stages of the disease. METHODS: We performed a clinical observation of cutaneous manifestations in 450 patients who were diagnosed with viral hepatitis. RESULTS: 1. Cutaneous manifestations were found in 383(85.1%) patients. Patients with a longer duration seemed to have skin lesions more frequently. 2. The frequency of cutaneous manifestations was highest in HAV(94.4%) and HBV(84.9%) serotypes. The most common cutaneous manifestation was pruritus(32.4%) in all studied subjects. In HBV hepatitic patients, the most common cutaneous manifestation was pruritus(35.4%), in HCV hepatitic patients, vasculitic purpura(74.5%), in HAV hepatitic patients, urticaria(88.8%), in the hepatitic patients with the mixed form, spider angioma(30.2%) and vasculitic purpura(30.2%). 3. Urticarial lesions in non-HCV hepatitis were of the lymphocytic vasculitis type but HCV hepatitis was associated with neutrophilic vasculitis. The purpuric lesions with HCV hepatitis were of the neutrophilic vasculitis type while lymphocytic vasculitis was present in non-HCV hepatitis. 4. The most severe pruritus was present in HBV hepatitic patients. CONCLUSION: The cutaneous manifestations in viral hepatitis have different clinical features depending on the viral types.
Hepatitis*
;
Humans
;
Korea
;
Neutrophils
;
Pruritus
;
Skin
;
Spiders
;
Vasculitis
9.Pseudoatrophoderma Colli.
Min Geol LEE ; Kyu Kwang WHANG ; Dong Kun KIM
Korean Journal of Dermatology 1985;23(4):471-474
Pseudoatrophoderma colli is a symptomless, persistent, persistent, pigmentary disorder involving the neck and upper thorax first described by Becker and Muir in. 1934 The lesion is usually localized to the neck and upper part of the thorax. It consists of macules or papules which show pigmentation or papules which show pigmentation or depigmentation and look atrophic. Histological examination shows hyperkeratosis, hypogranulosis, focal acanthosis and perivascular lymphocytic infiltration. We present herein a case of pseudoatrophoderma colli which showed symptomless, mottled, pigmentated macules involving the neck clinically and compatible findings histopathologically.
Neck
;
Pigmentation
;
Thorax
10.The Effect of Pelvic Floor Muscle Training with Biofeedback and Functional Electrical Stimulation for Genuine Stress Urinary Incontinence.
Jong Min YUN ; Sang Jin KIM ; Kyu Sung LEE
Korean Journal of Urology 2000;41(5):627-632
No abstract available.
Biofeedback, Psychology*
;
Electric Stimulation*
;
Pelvic Floor*
;
Urinary Incontinence*