1.A case of Idiopathic Neonatal Chylothorax Treated with Thoracostomy and Medium Chain Triglyceride - Containing Diet.
Kyu Dong CHA ; Yoon Jung CHO ; Sang Lak LEE
Journal of the Korean Society of Neonatology 1999;6(2):253-257
Chylothorax is the most common cause of pleural effusion in the neonatal period and is defined as an effusion of lymph in the pleural cavity. We report a case of chylothorax in a 13-day-old male who was admitted due to respiratory difficulty. Chest AP showed pleural effusion of the left lung and milky yellow fluid was aspirated via thoracentesis upon which laboratory and lipoprotein electrophoresis of pleural fluid revealed findings compatible with that of chylothorax. Due to reaccumulation of chyle after daily thoracentesis, chest tube was inserted at the 4th hospital day, and MCT containing diet was given. He was discharged on the 21st hospital day in good health, and revealed no recurrence for 3 months during outpatient follow up visits.
Chest Tubes
;
Chyle
;
Chylothorax*
;
Diet*
;
Electrophoresis
;
Follow-Up Studies
;
Humans
;
Infant, Newborn
;
Lipoproteins
;
Lung
;
Male
;
Outpatients
;
Pleural Cavity
;
Pleural Effusion
;
Recurrence
;
Thoracostomy*
;
Thorax
;
Triglycerides*
2.Effect of an Obesity Management Program on Body Weight, Body Mass Index and Physiological Index of High School Girl Students.
Journal of Korean Academy of Nursing 2004;34(7):1362-1371
PURPOSE: This study was to examine the effect of an obesity management program on the body weight, body-mass index, and physiological index of obese female high school students. METHOD: Students from one school were selected as the experimental group, and students from another school as a control group so the latter group wasn't exposed to the experiment. The experimental group and the control group were each organized with 20 students. The experimental group received 60 minutes of behavior modification once a week, for eight weeks. RESULT: The Body weight, and Body mass-Index of the experimental group significantly decreased after the obesity management program. Total-cholesterol, T-G, and LDL-C significantly decreased and HDL-C increased in the experimental group. Total-cholesterol, T-G, LDL-C and HDL-C between the experimental group and control group showed significant differences. CONCLUSION: These results indicate that the obesity management program had a great effect on decreasing the body weight and body-mass index of the female obese high school students, normalizing their physiological index. In conclusion, this program turned out to be one of the safest and most effective obesity-management methods that could be applied to female high school students.
Adolescent
;
*Behavior Therapy
;
*Body Mass Index
;
*Body Weight
;
Female
;
Humans
;
Lipids/*blood
;
Obesity/physiopathology/*therapy
3.Effects of nitric oxide synthase inhibitors on osteoclast-like cell formation.
Seung Kyu AHN ; Jung Kun KIM ; Kyung Suk CHA
Korean Journal of Orthodontics 1995;25(6):715-722
Orthodontic tooth movement in response to orthodontic force results from actions of osteoclasts and osteoblasts in the cell level. Convincing evidence has now been provided to support the view that osteoclasts are derived from mononuclear cells that originate in the bone marrow or other hematopoietic organs and they migrate to the bones via vascular routes. Nitric oxide(NO), which accounts for the biological properties of endothelium-derived relaxmg factor(EDRF), is the endogenous stimulator of soluble guanylate cylase. The discovery of the formation of nitric oxide(NO) from L-arginine in mammalian tissues and its biologioal roles has, in the last 7 years, thrown new light onto many areas of research. Data from experiments in vitro showed that N-metyl-L-arginine(L-NMA) and L-nitro-L-arginine(L-NAME) are competitive inhibitors of nitric oxide synthase. This study suggest that the multinucleated cells in our culture have characteristics of osteoclasts and that the potential bone cell activity of nitric oxide in vitro may be mediated in part by stimulation of marrow mononuclear cells to form osteoclast-like cells. Bone marrow cells were obtained from tibia of 19-days old chick embryo. After sacrifice, tibia was quickly dissected and the bone were then split to expose the medullary bone. The cells were attached for 4 hours and the nonadherent cells were collected. Marrow cells were cultured in 96-well plate in medium 199. To examine the number of TRAP-positive multinucleated cells(MNCs), 10(-8) M Vit-D3 and various concentration of L-NMA and L-NAME were added at the beginning of cultures and with each medium change. After 7 days of culture, tartrate-resistant acid phosphatase(TRAP) staining was performed for microscopic evaluation. Cells having more than three nuclei per cell were counted as MNCs. The observed results were as follows; 1. 1,25-dihydroxyvitamine D3 stimulated the osteoclast-like multinucleated cells in cultures of chick embryo bone marrow. 2. Nitric oxide synthase inhibitors(NOSI ; N-NMA, N-NAME) stimulated the osteoclast-like cells in cultures of chick embry bone marrow. 3. 1,25-dihydroxyvltamine D3 and nitric oxide synthase inhibitors did not appear to have additive effect on the generation of TRAP-positive MNCs. These results suggest that nitric oxide synthase inhibitors may stimulate the osteoclast-like multinucleated cell formation and fusion in cultures of chick bone marrow.
Animals
;
Arginine
;
Bone Marrow
;
Bone Marrow Cells
;
Chick Embryo
;
NG-Nitroarginine Methyl Ester
;
Nitric Oxide Synthase*
;
Nitric Oxide*
;
Osteoblasts
;
Osteoclasts
;
Tibia
;
Tooth Movement
4.An Association Study of COMT Gene Polymorphism with Korean Alcoholism.
Min Jung KIM ; Byung Hwan YANG ; Jung Sik LEE ; Young Gyu CHA ; Taek Kyu PARK
Journal of the Korean Society of Biological Psychiatry 2001;8(1):111-115
An association study with Korean alcoholic patients(n=50) and normal controls(n=53) was performed to find the relationship between catechol-O-methyltransferase(COMT) gene polymorphism and alcoholism using polymerase chain reaction-restriction fragment length polymorphism. When we compared the allele and genotype frequencies of Nla III COMT gene polymorphism in alcoholism and normal controls, there was no significant difference between two groups. Our results do not support an association between the Nla III polymorphism of COMT gene and alcoholism.
Alcoholics
;
Alcoholism*
;
Alleles
;
Genotype
;
Humans
5.Obstructive sleep apnea syndrome in children: Epidemiology, pathophysiology, diagnosis and sequelae.
Sun Jung CHANG ; Kyu Young CHAE
Korean Journal of Pediatrics 2010;53(10):863-871
The prevalence of pediatric obstructive sleep apnea syndrome (OSAS) is approximately 3% in children. Adenotonsillar hypertrophy is the most common cause of OSAS in children, and obesity, hypotonic neuromuscular diseases, and craniofacial anomalies are other major risk factors. Snoring is the most common presenting complaint in children with OSAS, but the clinical presentation varies according to age. Agitated sleep with frequent postural changes, excessive sweating, or abnormal sleep positions such as hyperextension of neck or abnormal prone position may suggest a sleep-disordered breathing. Night terror, sleepwalking, and enuresis are frequently associated, during slow-wave sleep, with sleep-disordered breathing. Excessive daytime sleepiness becomes apparent in older children, whereas hyperactivity or inattention is usually predominant in younger children. Morning headache and poor appetite may also be present. As the cortical arousal threshold is higher in children, arousals are not easily developed and their sleep architectures are usually more conserved than those of adults. Untreated OSAS in children may result in various problems such as cognitive deficits, attention deficit/hyperactivity disorder, poor academic achievement, and emotional instability. Mild pulmonary hypertension is not uncommon. Rarely, cardiovascular complications such as cor pulmonale, heart failure, and systemic hypertension may develop in untreated cases. Failure to thrive and delayed development are serious problems in younger children with OSAS. Diagnosis of pediatric OSAS should be based on snoring, relevant history of sleep disruption, findings of any narrow or collapsible portions of upper airway, and confirmed by polysomnography. Early diagnosis of pediatric OSAS is critical to prevent complications with appropriate interventions.
Achievement
;
Adult
;
Appetite
;
Arousal
;
Child
;
Dihydroergotamine
;
Early Diagnosis
;
Enuresis
;
Failure to Thrive
;
Headache
;
Heart Failure
;
Humans
;
Hypertension
;
Hypertension, Pulmonary
;
Hypertrophy
;
Neck
;
Neuromuscular Diseases
;
Obesity
;
Polysomnography
;
Prevalence
;
Prone Position
;
Pulmonary Heart Disease
;
Risk Factors
;
Sleep Apnea Syndromes
;
Sleep Apnea, Obstructive
;
Snoring
;
Somnambulism
;
Sweat
;
Sweating
6.Endovascular Treatment of Giant Basilar Trunk Aneurysm: Case Report.
Korean Journal of Cerebrovascular Disease 2001;3(1):83-87
Treatment of giant aneurysms of the basilar artery remains difficult and controversial. Especially, surgical treatment of the basilar trunk aneurysm have a potential morbidity or mortality due to its anatomical environment and the complicated surgical exposure. A 32-year-old female presented with an unruptured, giant basilar trunk aneurysm manifesting as brainstem compression signs and cranial nerve dysfunction. Cerebral angiography disclosed a giant aneurysm with a wide neck and an intra-aneurysmal thrombus arising from the mid-basilar artery. Aneurysm was embolized with Guglielmi detachable coils; and complete occlusion of the aneurysm was obtained.
Adult
;
Aneurysm*
;
Arteries
;
Basilar Artery
;
Brain Stem
;
Cerebral Angiography
;
Cranial Nerves
;
Female
;
Humans
;
Mortality
;
Neck
;
Thrombosis
7.The effect of vincristine and adriamycin on the phagocytic function of reticuloendothelial system of rats.
Hyun Suk LEE ; Jong Soo KIM ; Jung Soo KIM ; Kyu Cha KIM ; Ho Yeul CHOI
Journal of the Korean Pediatric Society 1982;25(9):880-887
No abstract available.
Animals
;
Doxorubicin*
;
Mononuclear Phagocyte System*
;
Rats*
;
Vincristine*
8.Bone Changes in Childhood Leukemia.
In Soo CHOI ; Jong Soo KIM ; Jung Soo KIM ; Kyu Cha KIM ; Yea Seong YOUN
Journal of the Korean Pediatric Society 1983;26(2):143-149
No abstract available.
Leukemia*
9.An Analysis of Factors Influencing Job Satisfaction among Nurses Working in College Health Centers.
Journal of Korean Academy of Fundamental Nursing 2013;20(3):259-268
PURPOSE: The purpose of this study was to identify factors influencing job satisfaction among nurses working in college health centers in order to enhance their role functions and to increase their work capabilities. METHOD: In this study a cross-sectional survey was used to collect data from 106 nurses working in college health centers. Collected data were analyzed using frequency, Pearson correlation coefficients, independent t-test, one-way ANOVA and multiple regression with the SPSS 20.0. RESULTS: Mean scores for self-efficacy, job stress and job satisfaction for the participants were 3.86 (5-point scale), 2.51 (5-point scale) and 3.37 (5-point scale) respectively. There was a negative correlation between self-efficacy and job satisfaction (r=-.653, p<.001). Factors influencing job satisfaction were job stress (beta=-.58, p=<.001), level of perception among the nurses that they were contributing to the health promotion of students (beta=-.21, p=.005) and marital status (beta=.17, p=.029). These 3 elements accounted for 47.7% of the variance in job satisfaction. CONCLUSIONS: The results indicate that reduction in job stress and increase in the perception that nurses are contributing to the promotion of students' health are important to reinforce the role function of nurses and to increase their work capabilities.
Cross-Sectional Studies
;
Health Promotion
;
Humans
;
Job Satisfaction
;
Marital Status
10.Sleep Disturbances in Children Younger than 36 Months of Age with Iron Deficiency Anemia.
Hae Jung KIM ; Seon Kyeong RHIE ; Kyu Young CHAE ; Heui Seung JO ; Moon Kyu KIM
Journal of the Korean Child Neurology Society 2013;21(2):59-67
PURPOSE: Iron deficiency anemia (IDA) and sleep problems are prevalent in infancy and early childhood and are more associated with poor cognitive, motor, and social-emotional development. The aim of this study was to access the relationship between IDA and sleep disorders in a population of Korean children <36 months. METHODS: One hundred and ninety six children, who visited the outpatient clinic for a routine check-up were consecutively enrolled from March 2011 to March 2012. All parents answered a questionnaire about sleep patterns of their children using a modified expanded version of the Brief Infant Sleep Questionnaire. Among the subjects, 93 children with strong evidence of sleep disordered breathing were excluded. Hundred three children were then divided into the IDA group (n=23) and the control group (n=80). Sleep-wake parameters and prevalence of sleep disturbances were compared between the two groups. A multivariate analysis was performed to determine the independent risk factors for sleep disturbances in children. RESULTS: Children with IDA had more frequent nocturnal waking, restless sleep, and inconsolable crying during sleep than those in the control. Children with IDA also had more inappropriate sleep onset associations. No difference in sleep-wake parameters was observed between the two groups. The presence of IDA in children and maternal anemia were significant independent risk factors for sleep disturbances in children <36 months. CONCLUSION: The results suggest that prevention, early detection, and treatment of IDA would be important for good sleep in young children <36 months.
Ambulatory Care Facilities
;
Anemia
;
Anemia, Iron-Deficiency
;
Child
;
Crying
;
Humans
;
Infant
;
Iron
;
Multivariate Analysis
;
Parents
;
Prevalence
;
Surveys and Questionnaires
;
Risk Factors
;
Sleep Apnea Syndromes
;
Sleep Wake Disorders