PURPOSE: This study aimed to examine the changes in the outbreak of acute gastroenteritis, rotavirus gastroenteritis after the introduction of the rotavirus vaccine in Korea. METHODS: The current study investigated the number of inpatients in the pediatric ward of Inje University Sanggye Paik Hospital during the periods of 2005-2006 and 2011-2012. A retrospective analysis was conducted on the medical records of 2,840 patients <5 years of age who were hospitalized at Inje University Sanggye Paik Hospital in these time periods. RESULTS: When we compared 2 separate sets of data from before (2005-2006) and after (2011-2012) vaccine introduction, there were statistically significant decreases in the number of patients who were hospitalized for acute gastroenteritis across all of the groups of patients <5 years of age except those <2 months of age. The number of patients with rotavirus gastroenteritis in all age groups declined except for children <2 months of age and those 2-5 months of age. CONCLUSION: These results show that after the introduction of a rotavirus vaccine in Korea, the incidence of rotavirus gastroenteritis decreased in 6-59-month-old patients hospitalized for acute gastroenteritis.
Child* ; Gastroenteritis* ; Humans ; Incidence ; Inpatients ; Korea ; Medical Records ; Retrospective Studies* ; Rotavirus Vaccines* ; Rotavirus* ; Tertiary Care Centers* ; Vaccination

The aim of the investigation was to study the efficacy and safety of Famotidine (Gaster), a new, potent, histamine H-receptor antagonist. The Famotidine (40 mg p.o.h.s) was administered to 22 patients with 33 peptic ulcers for 4 weeks. Follow up checking was done at 2 week and 4 week by endoscopy and physical examination. All patients were carefully evaluated at regular intervals for adverse drugh reactions by clinical and laboratory examinations. By the end of study, 97% of the ulcers were healed by endoscopically and rapid and complete relief of epigastric pain was observed in all patients. Famotidine treatment was well tolerated and no alterations in laboratory tests were noted. Therfore, Famotidine was proved effective in the treatment of peptic ulcers (especially multiple ulcers) and was well tolerted on the short-term basis.
Endoscopy ; Famotidine* ; Follow-Up Studies ; Histamine ; Humans ; Peptic Ulcer* ; Physical Examination ; Ulcer

No abstract available.
Meningitis*

No abstract available.
Glutathione Transferase* ; Glutathione* ; Schistosoma japonicum* ; Schistosoma*

The authors report an extremely rare case of a massive hyperostotic meningioma en plaque, which had characteristics of unique bony growth. A 34-year-old man presented with a palpable solid mass in the left cranial region that had gradually grown in size with a broad base on the calvarium for 8 years. Radiologically, the area involved by the mass ranged from the sphenoid bone to the frontal, parietal, temporal, and occipital bones. Three-dimensional CT revealed multiple growing spiculate features on the inner and outer cranial surface. Even though the radiologic features resembled fibrous dysplasia, it was histologically found to be a type of meningioma.

We report a case of trichorrhexis nodosa in a 27-year-old male. Scanning electron microscopic findings reveals those of typical trichorrhexis nodosa nodal swelling of affected hair showed longitudinal fissures and fractures in the cortex. A paintbrush effect was noted at the site of fracture. Simple avoidance of trauma gave some regrowth of hairs.
Adult ; Hair ; Humans ; Male

No abstract available.
Hypertrophy, Left Ventricular* ; Kidney Failure, Chronic*

The purine antimetabolite 6-Mercaptopurine (6-MP) has been in clinical use for over 30 years and is still a widely used agent in the treatment of childhood acute lymphoblastic leukemia. The bioavailibility, clinical efficacy and toxicity of 6-MP administered orally for maintenance therapy of children with acute lymphoblastic leukemia are highly variable in many studies, as well as at differnt times in same patient. there are many factors affecting the bioavailibility of 6-MP. The most notably factor being that concomitantly administered drugs and foods might contribute to a decrease in the bioavailibity of this drug. In our sociocultural environment milk is a major constituent of child's foods. Cow's milk contains a high concentration of xanthine oxidase, which could potentially transform 6-TM into 6-thioxanthine (6-TX) and 6-thiouric acid (6-TUA) which have no more therapeutic effects. In this study, we evaluated the effect of various milk products on the bioavailability of 6-MP. Incubation at 37degrees C for 30 min raw or pasteurized milk resulted in transformation of a large quantity of clinically relevant concentration of 6-MP into 6-TUA. The concomitant adminstration of folic acid and allopurinol has markedly inhibitory effect on the 6-MP destroying activity of milk at clinically relevant concentrations. These observations may help to optimize modalities of administration of 6-MP for the treartment of patients with childhood leukemia.
6-Mercaptopurine* ; Allopurinol ; Biological Availability* ; Child ; Complement Factor B ; Folic Acid ; Humans ; Leukemia ; Milk* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Xanthine Oxidase

PURPOSE: This study is aimed at obtaining the information on the physical fitness level of female flight attendants at a local airline. METHODS: The subjects are 2,409 female flight attendants who have had medical examination and physical fitness tests at an airline medical center from January 2 to December 30, 2008. The independent variables include socio-demographic & behavioral characteristics, and medical examination results, whereas the dependent variable is their physical strength score representing their fitness level. RESULTS: Factors that affect the fitness strength score are age, flight hours per year, and fasting blood sugar level. It is found that physical fitness level is higher when the subjects are over 35, on board for over 850 hours per year and their fasting blood sugar level is over 100 mg/dL. CONCLUSION: It is concluded that for the improvement of flight attendants' health, more exercise to develop cardio-respiratory endurance and muscular strength is needed, and further study needs to be done to develop fitness enhancement programs considering flight attendants' job characteristics, working years, and flight hours per year, and programs for those returning to their workplace after a long-term leave, and new employees.
Blood Glucose ; Fasting ; Female ; Humans ; Physical Fitness

Lenticular bum can occur as complication after laser iridotomy or retinal photocoagulation. Some authors have, indeed, reported the cases in which focal lenticular opacity developed after laser iridotomy or retinal photocoagulation. Fortunately, it was not progressive in short-term follow up study. When argon laser beam penetrates ocular media, a portion of it is absorbed by lens. So visible lenticular opacity is not developed after argon retinal photocoagulation if lens is clear. But it is not known whether subclinical lenticular opacity can occur after argon laser retinal photocoagulation. We focused argon laser beam onto anterior lens capsule in 35 black and brown rabbit and evaluated development of subclinical lenticular opacity with densitometer 1 and 8 weeks later. We also analyzed lens protein 1 week later. Argon laser energy used was below 20 Joules. The following results were obatined. 1. Lenticular opacity was detected by densitometer in all cases, but it was not detected by slit-lamp. 2. Amount of lenticular opacity was in direct proportion to argon laser energy(p<0.001). 3. Lenticular opacity detected on the 1st week by densitomer was not detectable on the 8th week. 4. The lens protein changes of senile cataract were not found in the lenticular opacity detected on the 1st week.
Argon* ; Cataract ; Follow-Up Studies ; Light Coagulation* ; Retinaldehyde*