Clinical types of onychorpycosis, consist of distal subungual orychomycosis, white superficial onychomycosis, proximal subongual onychomycosis and candidal onychomycosis. White superficial onychomycosis aippears as white, sharply outlined areas on the surfaces of toenails. The fingernails are not affected. Trichophyton mentogrophytes, rarely Trichophyton rubrm, is the causa ive dermatophytes. The auther reports a case of white superficial onychomycosis of the fingernail caused by T. rubrm.
Arthrodermataceae ; Nails ; Onychomycosis* ; Trichophyton

Psoriasis is common cutaneous disorder involving 0.1~3% Of the general population and is characterized by its marked chronicity and recurrence. A variety of factors, rarging from heredity, environment to abnormal cytodynamics and biochemical perturbation have been implicated but never proved as causative. In recent years, many studies on psoriasis have been reported, showing the presence of certain immunologic abnormalities in patients with psoriasis, and some authors postulated that these immunologic abnormalities, particularly in cell mediated immunity, may play a key role in the pathogenesis of psoriasis. This study was undertaken to evaluate cell mediated immune status of patients with paoriasis using several immunologic parameters. A total of 70 patients (35 were male and 35 were female) between the ages of l:l and 70 years entered this study at the Department of Dermatology of Seoul National University Hospital from January 1980 through September 1980. Peripheral blood T lymphocytes(early and total) were enumerated by E-rosette technique in 55 patients. Delayed cutaneous hypersensitivity reaction was measured in 3O patients using intradermal candidin, trichophytinand PPD. Active sensitization with DNCB was performed in 30 patients.
Dermatology ; Dinitrochlorobenzene ; Heredity ; Humans ; Hypersensitivity ; Immunity, Cellular ; Male ; Psoriasis* ; Recurrence ; Seoul

Progressive cribriform and zosteriform hyperpigmentation (PCZH) is a distinctive clinical entity first described by Rower et al. in 1978. It is characterized by a single area of uniformly tan cribriform macular pigmentation in a zosteriform distriggtjpp with no preceding history of skin rash, injury or inflammation. It begins well after birth with gradual extension and is not associatad with any other cutaneous or internal abnormalities. Histologically, there is a mild increase in melanin pigment in the basal cell layer and complete absence of nevus cells. Recently, we observed clinical and histological featurea of 5 cases of PCZH. The age at onset ranged from 4 to 35 years. The lesions were unilaterally distributed on face, neck, chest, or abdomen. Histologically there was a mild increase in melanin pigment in the basal cell layer. PCZH must be differentiated from Beckers hairy nevus which begins with a unilateral lesion of irregularly macular pigmentation but occasionally it may be multiple or bilateral. In early stage, overgrowth of hairs may be absent but after a few years it is usually present. PCZH is characterized by uniformly tan cribriform pigmentation in zosteriform distribution, which is unilateral and does not cross the midline of the body. Overgrowth of hairs is absent even after a few years. So the lesions of Beckers hairy nevus previously reported, which were unilateral and did not cross the midline of the body and did not show overgrowth of hairs even after a few years, must be called progressive cribriform and zosteriforrn hyperpigmentation.
Abdomen ; Exanthema ; Hair ; Hyperpigmentation ; Inflammation ; Melanins ; Neck ; Nevus ; Parturition ; Pigmentation ; Thorax ; Triacetoneamine-N-Oxyl

The study was undertaken to clarify any quantitative abnormalities in peripheral blood T lymphocytes and T subsets, mediating cell meliated immunity, and the presence of any relation between the degree of quantitative abnormalities and extent of skin lesions and activity of disease in patients with psoriasis by monoclonal antibodies. The results were as follows. 1. Mean percentages of total and suppressor T lymphocytes in 39 patients with psoriasis are significantly decreased as compared with those in 32 controls. Mean ratio of percentage of helper T lymphocytes to that of suppressor Tlymphocytes in 39 patients with psoriasis are significantly increased as compared with that in 32 controls. 2, As classified into three groups according to extent of skin lesions (E: less than 5% E,: 5-30%, and E,: more than 30%), mean pereentages of total T lymphocytes in E, and E, psoriasis group and those of suppressor T lymphocytes in all three psoriasi., groups are significantly decreased as compared with those in controIs. Mean percentages of helper T lymphor,ytes in L psoriasis group and mean ratios of percentage of helper T lymphocytes to that of suppressor T lymphocytes in E, and E, psoriasis groups are significantly increased as compared with those in controls. 3. Cis classified into three groups according to activity of disease (A,: stationary, A,: active, peripherally spreading and A,: active, small papules spreading), mean percentage of total T lymphocytes in peripheral blood lymphocytes in A, psoriasis group and those of suppressor T lymphocytes in all three psoriasis group are significantly decreased as compared with those in controls. Mean percentages of helper T lymphocytes and mean ratios of percentage if helper T lymphocytes to that of suppressor T lymphocytes in A, and A, psorixsis groups are significantly increased as compared with those in controls. These results clarified that there are quantitative abnormalities in peripheral blood I' lymphocytes and T subsets in patients with psoriasis and the degrees of abnorrnalities are related to extent of skin lesions and activity of disease. The aanorrnalities in peri.pheral blood T lymphocytes and T subsets in patients with psoriasis seem to be attributed to primary defect of suppressor T lymphoytes.
Antibodies* ; Antibodies, Monoclonal ; Humans ; Lymphocytes ; Negotiating ; Psoriasis* ; Skin ; T-Lymphocytes*

Glutaraldehyde is commonly used as a biocide to disinfect delicate instruments such as dental instruments, to treat warts, hyperhidrosis and bullous diseases and as a preservative in various materials. Contact sensitivity to glutaraldehyde may not be detected, because it is not included in the standard screening chemicals recommended in the screening tests. We report a case of allergic contact dermatitis caused by Wydex(2% glutaraldehyde). A 54-year-old female made a visit to our departrnent with eczematous dermatitis of both hands, neck and face. She worked as a cleaner in delivery room and newborn nursery, and had developed the dermatitis 1 month after Wydex' containing 2% glutaraldehyde had been to clean the rooms. She had no family or personal history of atopy or contact dermatitis. Patch tests with Korean Standard(KS-1000) and Wydex were performed, and patch tests with 2% glutaraldehyde, 0.2% gluteraldehyde and rubber mix followed. The positive results were, Wydex 2% ++, 0.2% +, 0.02% + and. glutaraldehyde 2% aq. +, 0.2% aq. + on day 2 and day 4. We confirmed that the skin lesions had been caused by Wydex . The symptoms were eradicated after she changed her work environment and there has been no evidence of recurrence.
Delivery Rooms ; Dental Instruments ; Dermatitis ; Dermatitis, Allergic Contact* ; Dermatitis, Contact ; Eczema ; Female ; Glutaral* ; Hand ; Humans ; Hyperhidrosis ; Infant, Newborn ; Mass Screening ; Middle Aged ; Neck ; Nurseries ; Patch Tests ; Recurrence ; Rubber ; Skin ; Warts

A statistical study was done on 2205 skin tumors filed at Department of Clinical Pathology, Han Kang and Kang Nam Sacred Heart Hospital during last 10 years from 1980 to 1989. The results were summarized as follows : 1. The number of skin tumor surveyed was 2205 among total 67931 biopsy specimens, 2052 benign skin tumors, 153 malignant tumors. 2. The specimens were requested from the Department of Surgery(707 cases, 32.1 %), Dermatology(618 cases, 28.0%), Plastic Surgery(354 cases, 15.79o), and Or thopedic Surgery(223 cases, 10.1% ). 3. Among 2052 benign skin tumors, the frequently observed tumors were epidermal cyst(577 cases, 28.1%), lipoma(398 cases, 19.4%), melanocytic nevus(121 cases, 5.9 %), dermatofibroma(74 cases, 3.6%), cavernous hemangioma(72 cases, 3.5%), ea.ch of pilmatricoma and neurofibroma(63 cases, 3.1% ), granuloma pyogenicum(57 cases, 2.8%), neurilemmoma(53 cases, 2.6%), seborrheic keratosis(45 cases, 2.2%), soft fibroma(45 cases, 2.2%). 4. Among 153 malignant tumors, the frequently observed tumors were squamaus cell carcinoma(50 cases, 32.7%), basal cell carcinoma(45 cases, 29.4%), malignant melanoma(8 cases, 5.2%), Bowens disease(7 cases, 4.6%), metastatic skin tumors(7 cases, 4.6%) in order. Male to female ratio of malignant tumors was 1.6:1 and the peak age incidence was in 6th decade. 5. Male to female ratio of squamous cell carcinoma was 3.2:1 and of basal cell carcinoma 1: 1.3. The peak age incidences of both squamous cell carcinoma and basal cell carcinoma were 6th decade. The predilection sites of squmous cell carcinoma were face, neck and genitalia and those of basal cell carcinoma were face, lower extremities, neck and trunk.
Biopsy ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Female ; Genitalia ; Granuloma ; Heart ; Humans ; Incidence ; Lower Extremity ; Male ; Neck ; Pathology, Clinical ; Skin* ; Statistics as Topic

No abstract available.
Nails ; Onychomycosis

anserine folliculosis (Padilha-Gonqalves, 1977) is a skin disease occurring on the limited areas of the skin receiving prolonged friction and/or pressure by the other part(s) of the naked skin of the patient. Padilha-Goncalves named traumatic anserine folliculosis by stressing the etiologic factor, the pressure and friction, the goose skin appearance and the follicular nature of the basic skin lesions. A 7-year-old girl developed typical features of traumatic anserine folliculosis on the chin who had the habit of resting the chin on the right knee for 5 years while painting.

No abstract available.
Stevens-Johnson Syndrome*

Candidiasis is an acute or chronic infection caused most commonly by Candida albicans and occasionally by other species of the genus Candida. The superficial cutaneous candidiasis is varied; oral Candidiasis, perieche, candidal vulvovaginitis, candidal balanitis, candidal intertrigo, erosio interdigitalis blastomycetica, perianal candidiasis, candidal paronychia, candidal onychia, chronic mucocutaneous candidiasis, congenital cutaneous candidiasis, and candidid. Diagnosis can be made by typical appearance of the clinical lesions and the presence of satellite vesicopustules. This can be confirmed by KOH examination and culture of skin scrapings. Treatment is the correction of predisposing factors, topical therapy of imidazoles and/or systemic administration of itraconazole or fluconazole.
Balanitis ; Candida ; Candida albicans ; Candidiasis ; Candidiasis, Chronic Mucocutaneous ; Candidiasis, Cutaneous* ; Candidiasis, Oral ; Causality ; Diagnosis ; Fluconazole ; Imidazoles ; Intertrigo ; Itraconazole ; Male ; Paronychia ; Skin ; Vulvovaginitis