No abstract available.
Chickenpox*

The authors found 3 cases of retinitis pigmentosa inversus who had characteristics that age of onset is between fifth and sixth decade, retinal lesion was seen around the optic disc and along the retinal vascular arcade, margin is discrete, and peripheral retina is morphologically normal. The authors performed routine ophthalmic examination, fluorescein angiography, electroretinography, electro-oculography. Fluorescein angiogram of retinitis pigmentosa inversus showed diffuse hyperfluoresce due to retinal pigment epithelium atrophy and partical hypofluoreseenee due to choriocapillary atrophy. Characteristic electroretinogram findings were moderate decrease of rod function and mild decrease of cone function. The authors also experienced 1 cases of peripapillary choroidal dystrophy and could differentiate it from retinitis pigmentosa inversus. Peripapillary choroidal dystrophy showed similar that of retinitis pigmentosa inversus in electroretinogram test, but showed diffuse and typical hypofluo rescence due to choriocapillary and retinal pigment epithelium atrophy according to the retinal lesion.
Age of Onset ; Atrophy ; Choroid* ; Diagnosis, Differential* ; Electroretinography ; Fluorescein ; Fluorescein Angiography ; Retina ; Retinal Pigment Epithelium ; Retinaldehyde ; Retinitis Pigmentosa* ; Retinitis*

No abstract available.

Sclerosing cholangitis is cholestatic disease, characterized by progressive fibrotic inflammation and obliteration af intrahepatic bile ducts and extrahepatic bile ducts and sometimes associated with ulcerative colitis. The pathogenesis of this disease is not understood well. In this disease, however, have been proposed infectious agent, endotoxin of bacteria and immunological event. In Europe and U.S.A., the incidence of sclerosing cholangitis associated with ulcerative colitis was between 2,4 and 4.0 percent. The association is strongest in patients with pancolitis, with a prevalenee of 5.5 percent, compared with patients with disease confined to the distal colon, with a prevalence of 0.5 percent. But, in Korea, it has not been reported sclerosing cholangitis associated with ulcerative colitis. A 30-year old man was diagnosed as an ulcerative colitis 9 years ago and has been followed up, intermittently. Recently, he has experienced hematochezia and dizziness. Colonoscopy showed active ulcerative colitis(pancolitis), blood chemistry elevated alkaline phosphatase and y-GTP. ERCP and liver biopsy specimen revealed sclerosing cholangitis. we concluded that this case was a sclerosing cholangitis as a complication of ulcerative colitis and the first case report of primary sclerosing cholangitis with ulcerative colitis in Korea, Hence, we reported a case of primary sclerosing cholangitis with ulcerative colitis with a review of literatures.
Adult ; Alkaline Phosphatase ; Bacteria ; Bile Ducts, Extrahepatic ; Bile Ducts, Intrahepatic ; Biopsy ; Chemistry ; Cholangiopancreatography, Endoscopic Retrograde ; Cholangitis, Sclerosing* ; Colitis, Ulcerative* ; Colon ; Colonoscopy ; Dizziness ; Europe ; Gastrointestinal Hemorrhage ; Humans ; Incidence ; Inflammation ; Korea ; Liver ; Prevalence ; Ulcer*

Sclerosing cholangitis is cholestatic disease, characterized by progressive fibrotic inflammation and obliteration af intrahepatic bile ducts and extrahepatic bile ducts and sometimes associated with ulcerative colitis. The pathogenesis of this disease is not understood well. In this disease, however, have been proposed infectious agent, endotoxin of bacteria and immunological event. In Europe and U.S.A., the incidence of sclerosing cholangitis associated with ulcerative colitis was between 2,4 and 4.0 percent. The association is strongest in patients with pancolitis, with a prevalenee of 5.5 percent, compared with patients with disease confined to the distal colon, with a prevalence of 0.5 percent. But, in Korea, it has not been reported sclerosing cholangitis associated with ulcerative colitis. A 30-year old man was diagnosed as an ulcerative colitis 9 years ago and has been followed up, intermittently. Recently, he has experienced hematochezia and dizziness. Colonoscopy showed active ulcerative colitis(pancolitis), blood chemistry elevated alkaline phosphatase and y-GTP. ERCP and liver biopsy specimen revealed sclerosing cholangitis. we concluded that this case was a sclerosing cholangitis as a complication of ulcerative colitis and the first case report of primary sclerosing cholangitis with ulcerative colitis in Korea, Hence, we reported a case of primary sclerosing cholangitis with ulcerative colitis with a review of literatures.
Adult ; Alkaline Phosphatase ; Bacteria ; Bile Ducts, Extrahepatic ; Bile Ducts, Intrahepatic ; Biopsy ; Chemistry ; Cholangiopancreatography, Endoscopic Retrograde ; Cholangitis, Sclerosing* ; Colitis, Ulcerative* ; Colon ; Colonoscopy ; Dizziness ; Europe ; Gastrointestinal Hemorrhage ; Humans ; Incidence ; Inflammation ; Korea ; Liver ; Prevalence ; Ulcer*

The authors performed conventional radial keratotomy(RK) in one eye(Keratotomy group) and RK with cyanoacrylate glue in the other eye(Glue group) for 5 rabbits and compared the diopteric changes between before and four weeks after operation. The refractory power(mean+/-SD) of the cornea meassured with keratometer before the RK was 51.53 +/- 0.77 diopter(D) in Keratotomy group and 51.98 +/- 0.84D in Glue group. It was reduced four week after RK by 4.73 +/- 1.94D and 7.15 +/- 1.46D. respectively. The change of refractive power between two groups showed a statistically significant difference(p<0.05). There was no statistically significant difference of astigmatism between two groups(p>0.05). Histologic examination was performed with 4 eyes of 2 rabbits 4 week after RK. It was found in both groups that same pattern of epithelial plug and irregulaly oriented collagen fibers in stroma. However, the epithelial plug was more prominent in RK group than in Glue group. In conclusion, it was found that that RK with cyanoacrylate glue was more effective in reduction of keratometic diopter than keratotomy alone and the reason seemed to be a decreased epithelial plug in a keratotomy wound.
Adhesives* ; Astigmatism ; Collagen ; Cornea* ; Cyanoacrylates* ; Keratotomy, Radial* ; Rabbits ; Wound Healing* ; Wounds and Injuries*

No abstract available.
Subarachnoid Hemorrhage, Traumatic*

Intracranial hypoglossal neurinomas are rare and only about fifty cases have been reported worldwidely. They usually present with hypoglossal nerve palsy preoperatively. The authors experienced, however, two cases of intracranial hypoglossal neurinomas without preoperative hypoglossal nerve palsy. One patient was operated using transcondylar retrosigmoid approach with C1 laminectomy and the other using midline suboccipital craniectomy with C1 laminectomy. Postoperatively hypoglossal nerve palsy was developed in both cases. Absence of preoperative hypoglossal palsy seemed to be related to somewhat different growth pattern in these two cases. When the tumor shows typical radiological findings of hypoglossal neurinoma, it must be included in differential diagnosis despite absence of preoperative hypoglossal nerve palsy.
Diagnosis, Differential ; Humans ; Hypoglossal Nerve Diseases* ; Hypoglossal Nerve* ; Laminectomy ; Neurilemmoma* ; Paralysis

Although the use of mesh reinforcement during large hiatal hernia repair may reduce the rate of recurrence, various mesh-related complications have been reported. A 65-year-old woman presented with dysphagia. The patient was diagnosed with a large hiatal hernia and treated with laparoscopic fundoplication and Collis gastroplasty with mesh repair. Six months after surgery, the patient presented with dysphagia and vomiting. Esophagogastroduodenoscopy showed migration of mesh material into the esophagogastric junction. We performed a proximal gastrectomy with mesh removal. The patient was discharged without any postoperative complications. Herein, we encountered a rare case requiring surgical treatment to resolve mesh-induced esophagogastric perforation after hiatal hernia repair. Meshassociated complications, such as erosion or migration, should be considered as they may be more common than previously reported. Additionally, these complications are currently underscored in clinical practice. Regarding mesh applications, symptoms of mesh-related complications, such as dysphagia, should be carefully monitored for early detection.

BACKGROUND/AIMS: Approximately 80% of Korean adults are infected with Helicobacter pylori. Although H. pylori is associated with the chronic gastritis, peptic ulcer, and gastric adenocarcinoma, only a small number of infected patients develop these conditions. Therefore, there may be more virulent disease-specific subtypes of H. pylori in patients with gastroduodenal disease. To investigate the disease- specific subtypes of cagA and vacA in Korea, evaluation was made on these subtypes of H. pylori. METHODS: Twenty two patients with chronic gastritis, 21 patients with duodenal ulcer, and 23 patients with gastric adenocarcinoma were examined. All patients underwent endoscopic biopsy. H. pylori was cultured and genomic DNA was extracted. PCR- based cagA and vacA were subtyped and vacuolating cytotoxin was assayed using HeLa cells. RESULTS: The presence of cagA was observed in 95.5%, 100%, and 95.7%, the vacA s1a subtype was detected in 100%, 90.5%, and 95.7%, the vacA m1b subtype was detected in 95.5%, 90.5%, and 95.7% in chronic gastritis, duodenal ulcer, and gastric adenocarcinoma, respectively. CONCLUSIONS: The H. pylori with cagA and subtype s1a/m1b vacA gene was predominant regardless of the type of gastroduodenal disease. There were no difference in the cagA and vacA subtypes of H. pylori among the chronic gastritis, duodenal ulcer, and gastric adenocarcinoma in Korea.
Adenocarcinoma* ; Adult ; Biopsy ; DNA ; Duodenal Ulcer* ; Gastritis* ; HeLa Cells ; Helicobacter pylori* ; Helicobacter* ; Humans ; Korea ; Peptic Ulcer