1.Larger Remaining Stomach Volume Is Associated With Better Nutrition and Muscle Preservation in Patients With Gastric Cancer Receiving Distal Gastrectomy With Gastroduodenostomy
Amy KIM ; Jung-Bok LEE ; Yousun KO ; Taeyong PARK ; Hyeonjong JO ; Jin Kyoo JANG ; Kyoungsuk LEE ; Kyung Won KIM ; In-Seob LEE
Journal of Gastric Cancer 2022;22(2):145-155
Purpose:
Weight loss and deterioration in body composition are observed in patients with gastric cancer (GC) following gastrectomy. This study aimed to investigate the impact of residual stomach volume (RSV) on the nutritional status and body composition of patients with GC treated with distal gastrectomy.
Materials and Methods:
In total, 227 patients who underwent minimally invasive distal gastrectomy with Billroth 1 anastomosis for stage I GC between February 2015 and May 2018 were enrolled. Clinicodemographic and laboratory data were collected from the GC registry. The RSV, abdominal muscle area, and subcutaneous/visceral fat areas were measured using computed tomography data.
Results:
A larger RSV was associated with a lower decrease in the nutritional risk index (P=0.004) and hemoglobin level (P=0.003) during the first 3 months after surgery, and better recovery at 12 months. A larger RSV demonstrated an advantage in the preservation of abdominal muscle area (P=0.02) and visceral fat (P=0.04) after surgery, as well as less reduction in weight (P=0.02) and body mass index (P=0.03).
Conclusions
Larger RSV was associated with improved nutritional status and better preservation of muscle and fat after distal gastrectomy.
2.Case Report of Kidney Paired Donation (KPD) with Desensitization: the Strategy and Experience of 3-Way KPD in Samsung Medical Center
Dongkyu OH ; Eun Suk KANG ; Shinae YU ; Kyoungsuk CHUN ; Wooseong HUH ; Hye Ryoun JANG ; Chan Woo CHO ; Nuri LEE ; Kyo Won LEE ; Hyojun PARK ; Jae Berm PARK ; Sung Joo KIM
Journal of Korean Medical Science 2018;33(5):e39-
As the need for the organ donation increases, strategies to increase kidney transplantation (KT) through expanded living donation have become essential. These include kidney paired donation (KPD) programs and desensitization in incompatible transplantations. KPD enables kidney transplant candidates with incompatible living donors to join a registry with other incompatible pairs in order to find potentially compatible living donor. Positive cross match and ABO incompatible transplantation has been successfully accomplished in selective cases with several pre-conditionings. Patients who are both difficult-to-match due to broad sensitization and hard-to-desensitize because of donor conditions can often be successfully transplanted through a combination of KPD and desensitization. According to the existing data, KPD can increase the number of KTs from living donors with excellent clinical results. This is also a cost-effective treatment as compared with dialysis and desensitization protocols. We carried out 3-way KPD transplantation with one highly sensitized, positive cross match pair and with two ABO incompatible pairs. Herein we report our first successful 3-way KPD transplantation in a single center. To maximize donor-recipient matching and minimize immunologic risk, KPD programs should use proper algorithms with desensitization to identify optimal donor with simultaneous two-, three- or more complex multi-way exchanges.
Dialysis
;
Humans
;
Kidney Transplantation
;
Kidney
;
Living Donors
;
Tissue and Organ Procurement
;
Tissue Donors