1.The effect of histamine on the production of interferongamma and interleukin-12 in peripheral blood mononuclear cells from patients with atopic dermatitis.
Dou Hee YOON ; Eun Kyoung LEE ; Chung Won KIM
Journal of Asthma, Allergy and Clinical Immunology 1999;19(3):459-467
No abstract available.
Dermatitis, Atopic*
;
Histamine*
;
Humans
;
Interleukin-12*
2.A Case of Behcet's Disease Associated with Intestinal Ulcers.
Eun Kyoung LEE ; Doo Hee YOON ; Tae Yoon KIM ; Chung Won KIM ; Woong Sik AHN
Korean Journal of Dermatology 1997;35(3):575-578
Behcets disease is a chronic systemic disease of unknown etiology, which is characterized by the recurrent orogenital ulcers, eye involvement and skin manifestations. In addition to the major symptoms, it includes arthritis, vasculitis, neurologic manifestations and gastrointestinal lesions. We report a case of Behcets disease associated with intestinal ulcers. The patient, a 45-year-old female, who had been treated under the diagnosis of Behcets disease for 4 years, presented with swallowing difficulty, vaginal discharge and persistent right lower abdominal pain. Colonoscopic examination showed multiple ulcers on the ileocecal region which is reported as the most common site of gastrointestinal Behcets disease. Gastrointestinal evaluation can be useful in diagnosis of Behcets disease, especially in a patient with gastrointestinal symptoms.
Abdominal Pain
;
Arthritis
;
Deglutition
;
Diagnosis
;
Female
;
Humans
;
Middle Aged
;
Neurologic Manifestations
;
Skin Manifestations
;
Ulcer*
;
Vaginal Discharge
;
Vasculitis
3.A case of primary hepatocellular carcinoma following vertical transmission of hepatitis B virus in a child.
Soo Kyoung LEE ; Ki Sup CHUNG ; Sun Won HONG ; Chan Il PARK
Journal of the Korean Pediatric Society 1991;34(11):1573-1580
No abstract available.
Carcinoma, Hepatocellular*
;
Child*
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Humans
4.The difference of interieukin - 4 and interferon - r production of Der p I stimulated T cells and effects of immunomodulator in house dust mite sensitive atopic and non - atopic individuals.
Jae Won OH ; Ha Baik LEE ; Yong Hoon CHUNG ; Yong CHOI ; Mi Kyoung SONG
Journal of Asthma, Allergy and Clinical Immunology 1999;19(4):548-556
BACKGROUND: Allergic diseases are characterized by immediate - and late - phase reactions to various allergens by the selective activation of a subset of CD4 + T cells. In response to allergen, T cells isolated from atopic donors are biased to low levels of IFN - y and high levels of IL - 4, and vice versa by T cells from non - atopic donor. Objective : The aim of this study was to evaluate the patterns of IL - 4 and IFN - y production after Der p I stimulation and the effect on the cytokine production from T cells by budesonide, disodium cromoglycate and cyclosporin A in atopic and non - atopic individuals. MATERIAL AND METHOD: Seven Der p I specific atopic and 7 non - atopic individuals were selected. We decided the 50% inhibiting concentration of each immunomodulator by lymphocyte proliferation assay, and measured their effects on the cytokine production in vitro by intracellular IL - 4, IFN - y staining and flow cytometry. Results and CONCLUSION: There was significant difference on stimulation index ( SI ) of production of IFN - y as well as IL-4 after Der p I stimulation between atopic and non-atopic individuals ( IL - 4 ; 1.57 +/- 0.7 : 0.98 +/- 0.2, p = 0.026, IFN - r : 1.45 +/- 0.5 : 0.95 +/- 0.2, p = 0.048 ). The synthesis of IL - 4, and IFN - r were significantly inhibited after the stimulation of every immunomodulators in atopic individuals, DSCG couldnt inhibit IL - 4 and IFN - r in nonatopic individuals. There was no significant difference in the inhibiting effect of these immunomodulators in both of them.
Allergens
;
Bias (Epidemiology)
;
Budesonide
;
Cromolyn Sodium
;
Cyclosporine
;
Dust*
;
Flow Cytometry
;
Humans
;
Immunologic Factors
;
Interferons*
;
Interleukin-4
;
Lymphocytes
;
Pyroglyphidae*
;
T-Lymphocytes*
;
Tissue Donors
5.Abrasion of abutment screw coated with TiN.
Seok Won JUNG ; Mee Kyoung SON ; Chae Heon CHUNG ; Hee Jung KIM
The Journal of Advanced Prosthodontics 2009;1(2):102-106
STATEMENT OF PROBLEM: Screw loosening has been a common complication and still reported frequently. PURPOSE: The purpose of this study was to evaluate abrasion of the implant fixture and TiN coated abutment screw after repeated delivery and removal with universal measuring microscope. MATERIAL AND METHODS: Implant systems used for this study were Osstem and 3i. Seven pairs of implant fixtures, abutments and abutment screws for each system were selected and all the fixtures were perpendicularly mounted in liquid unsaturated polyesther with dental surveyor. After 20 times of repeated closing and opening test, the evaluation for the change of inner surface of implant and TiN-coated abutment screw, and weight loss were measured. Mann-Whitney test with SPSS statistical software for Window was applied to analyze the measurement of weight loss. RESULTS: TiN-coated abutment screws of Osstem and 3i showed lesser loss of weight than non-coated those of Osstem and 3i (P < .05, Mann-Whitney test). CONCLUSION: Conclusively, TiN coating of abutment screw showed better resistance to abrasion than titanium abutment screw. It was concluded that TiN coating of abutment screw would reduce the loss of preload with good abrasion resistance and low coefficient of friction, and help to maintain screw joint stability.
Collodion
;
Friction
;
Joints
;
Tin
;
Titanium
;
Weight Loss
6.Detection of human papillomavirus DNA in respiratory tract papilloma using polymerase chain reaction(PCR).
Kwang Hyun KIM ; Myung Whan SUNG ; Won Ho CHUNG ; Young Min CHOI ; Kyoung Chan PARK
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):978-984
No abstract available.
DNA*
;
Humans*
;
Papilloma*
;
Respiratory System*
7.Distraction Arthroplasty of the Elbow
Han Koo LEE ; Moon Sang CHUNG ; Chong Suh LEE ; Kyoung Won PARK ; Kye Hyoung LEE
The Journal of the Korean Orthopaedic Association 1989;24(2):483-488
So many modalities have been suggested for the treatment of servere pain and ankylosis of the elbow with destruction of the articular surfaces. Among them, two major methods which have been widely used are resection arthroplasty and prosthetic replacement arthroplasty. However prosthetic replacement arthroplasty has some problems. Its indications are limited in the elderly inactive subjects. And there have been many kinds of complications including loosening and infection. Also, resection arthroplasty in now rarely indicated due to severe instability. From July 1980 to July 1987, we tried distraction arthroplasty in 8 cases of elbow with severe destruction of its articular surfaces, mainly in the young active persons. The average follow-up period was 45 months. The effect of distraction arthroplasty on relief of pain was not remarkable. The average increase in ROM, including that of one reankylosed elbow, was 51 ±22 degrees in flexion-extension and 48 ±23 degrees in pronstion-supinstion. No deep wound infection and instability which was main complication of resection arthroplasty were observed with our method of distraction arthroplasty. On the basis of functional results, the the results were excellent in 4, good in 1, fair in 2 and poor in 1 cases. In conclusion, distraction arthroplasty of the elbow can be one of the of effective methods reconstruction for the young active patients with the destruction of the elbow, if they are intelligent and motivated.
Aged
;
Ankylosis
;
Arthroplasty
;
Arthroplasty, Replacement
;
Elbow
;
Follow-Up Studies
;
Humans
;
Methods
;
Wound Infection
8.Clinical application of A-mode ultrasonography in maxillary sinusdisorders.
Young JANG ; Sang Deug CHUNG ; Cheol Min AHN ; Won Sang LEE ; Kyoung Hwa KANG ; Duk Hee CHUNG ; Chun Gil KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(3):553-560
No abstract available.
Ultrasonography*
9.Transient Increase of Higher-Order Aberrations after Lateral Rectus Recession in Children.
Kyoung Yul SEO ; Samin HONG ; Won Kyoung SONG ; Seung Ah CHUNG ; Jong Bok LEE
Yonsei Medical Journal 2011;52(3):527-529
The changes of higher-order aberrations (HOAs) after bilateral lateral rectus muscle recession were evaluated. Forty eyes of 20 children were enrolled and their wavefront information was assessed until postoperative 3 months. Even though the root mean square (RMS) of total aberration was not changed, the RMS of HOA was transiently increased at postoperative 1 week and returned to baseline level after 1 month. Among individual Zernike coefficient, secondary astigmatism, quadrafoil, secondary coma, secondary trefoil, and pentafoil showed similar tendency with the RMS of HOA. However, coma, trefoil, and spherical aberration were not changed. Regarding recession amount, it did not correlate with any Zernike coefficient. In summary, our data imply that the HOAs are transiently increased after lateral rectus recession surgery. These results are in collusion with previous reports that strabismus surgery induced transient corneal astigmatism.
Adolescent
;
Astigmatism/*etiology
;
Child
;
Child, Preschool
;
Exotropia/*surgery
;
Female
;
Humans
;
Male
;
Postoperative Care
;
*Postoperative Complications/epidemiology/pathology
;
Vision Tests
10.Pulse Oximetry and Skin Temperature Gradient as Diagnostic Tools of Successful Caudal Block.
Duk kyung KIM ; Kyoung Min LEE ; Won Kyoung KWON ; Chung Sik OH ; Sung Whan JANG
Korean Journal of Anesthesiology 2007;53(6):S19-S25
BACKGROUND: Though caudal block is a relative simple technique, it has not been widely used in adults because of a high failure rate. We assumed that any tests to quantify the changes of sympathetic tone in the affected areas would be excellent indicators of successful block. We tested the usefulness of two candidates (pulse oximetry plethysmographic waveform amplitude measured at 5th toe and calf minus 5th toe skin temperature gradient) as indicators of successful caudal block. METHODS: In 45 adult patients undergoing anal surgery with caudal block, these two variables were simultaneously measured at 2-min intervals for 20 min. A two-fold increase in the plethysmographic waveform amplitude from baseline and skin temperature gradient of 0oC were predefined as test criteria of successful block. RESULTS: While the sensitivity, specificity, positive predictive value, and negative predictive value of the skin temperature gradient test were 45.9%, 100%, 100%, and 9.1%, those of the plethysmographic waveform test were 86.5%, 100%, 100%, and 28.6%. The plethysmographic waveform test showed a significantly higher discriminative capacity than the skin temperature gradient test (94.9% vs. 48.7%, P < 0.05) CONCLUSIONS: Unlike the skin temperature gradient test, the plethysmographic waveform test showed a considerably high validity in detecting successful block. Considering its simple and real time monitoring potentials together with a high failure rate of caudal block in adults, we cautiously recommend it as a supplemental diagnostic tool to predict successful block, especially when verbal communication with patient is difficult.
Adult
;
Humans
;
Oximetry*
;
Sensitivity and Specificity
;
Skin Temperature*
;
Skin*
;
Toes