1.The effect of intravenous ritodrine hydrochloride on premature labor.
Jae Min LEE ; Yong Ho MOON ; Sun Jae HWANG ; Kyoung Hoon LEE ; Tae Ro KWAK
Korean Journal of Obstetrics and Gynecology 1993;36(7):3010-3016
No abstract available.
Female
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
2.GDC(Guglielmi Detachable Coil) Embolization for Carotid Cavernous Fistula - by Percutaneous Puncture of Superior Ophthalmic Vein -.
Kyoung Moon KWAK ; Young Joon KIM ; Bong Jin PARK ; Jung Nam SUNG ; Maeng Ki CHO
Journal of Korean Neurosurgical Society 1999;28(12):1810-1816
OBJECTIVE: For the treatment of carotid cavernous fistula(CCF), transarterial detachable balloon occlusion(DBO) is the method of choice. When it has failed to occlude the fistula, various embolization methods are used to treat the fistula. Transvenous embolization through the superior ophthalmic vein(SOV) is another method of treatment. The venous approach through the SOV after surgical dissection and exposure of this vein has been recommended by some delete, but(here) delete delete(an) alternative treatment method by percutaneous puncture of the SOV without surgical dissection(is described). METHODS: A 19-year-old woman admitted to our hospital two months after accident, presented with proptosis, chemosis, occulomotor and abducens nerve palsies, and bruit of the right eye. The authors tried DBO via transarterial route in initial treatment and the fistula was occluded with subsequent disapearance of bruit. However, 2 weeks later, she complained of recurence of bruit. Transarterial approach was attempted again, but the fistula hole was too small for this approach. The venous approach via SOV by percutaneous puncture was then tried. Puncture was made at the medial one third of the superior orbital rim and the fistula was embolized with Guglielmi detachable coils (GDCs). RESULTS: The fistula was completely occluded and no early and late complications noted. The patient's clinical symptoms were improved within a few days. CONCLUSION: Treatment of CCF by percutaneous puncture of the SOV is an alternative and effective method when other approaches are not feasible.
Abducens Nerve Diseases
;
Exophthalmos
;
Female
;
Fistula*
;
Humans
;
Orbit
;
Punctures*
;
Veins*
;
Young Adult
3.A Huge Neurilemmoma of the Cauda Equina.
Kyoung Moon KWAK ; Maeng Ki CHO ; Bong Jin PARK ; Jung Nam SUNG ; Young Joon KIM
Journal of Korean Neurosurgical Society 1999;28(11):1666-
We are report a case of surgically treated a huge neurilemmoma in the lower thoracic and lumbosacral areas. A 57-year-old women presented with low back pain, motor weakness of the both lower extremities and urination difficulty. Magnetic resonance imaging revealed a huge enhancing lesion at the L3-S1 levels and isolated two small enhancing lesions at the T12 and L1 level respectively. This case was treated with extensive laminectomy from T12 through S1 level and total resection. The pathological findings were consistent with neurilemmoma. The patient's preoperative neurologic deficit has been recovered and no postoperative complications developed.
Cauda Equina*
;
Female
;
Humans
;
Laminectomy
;
Low Back Pain
;
Lower Extremity
;
Magnetic Resonance Imaging
;
Middle Aged
;
Neurilemmoma*
;
Neurologic Manifestations
;
Postoperative Complications
;
Urination
4.GDC(Guglielmi Detachable Coil) Embolization Used in Carotid-Cavernous Fistula Incompletely Occluded by Detachable Balloon.
Kyoung Moon KWAK ; Young Joon KIM ; Tae Hoon KANG ; Jung Nam SUNG ; Hyun Koo LEE ; Maeng Ki CHO
Journal of Korean Neurosurgical Society 1997;26(12):1760-1765
For the treatment of carotid-cavernous fistula, detachable balloon occlusion(DBO) is the method of choice. When it fails, or when the fistula is incompletely occluded, alternative treatment methods include direct surgery and internal carotid artery occlusion at the proximal and distal portion of the fistula. Before ligation or occlusion of the internal carotid artery, however, coil embolization should be considered, as this preserves patent internal carotid artery. The authors used DBO in a 22-year-old male patient with carotid-cavernous fistula which developed after head injury. During the procedures the fistula was partially obstructed by one detachable balloon. In spite of several attempted occlusions with a second balloon, this could not be introduced into the small remnant fistula hole. The second stage of intervention involved embolization with a Guglielmi detachable coil(GDC) ; this was successfully introduced into the partially obstructed fistula, which was thus completely occluded, and the patient's clinical symptoms improved. In this case, GDC emboization was an effective tool for the treatment of carotid-cavernous fistula incompletely occluded by a detachable balloon.
Carotid Artery, Internal
;
Craniocerebral Trauma
;
Embolization, Therapeutic
;
Fistula*
;
Humans
;
Ligation
;
Male
;
Young Adult
5.GDC(Guglielmi Detachable Coil) Embolization Used in Carotid-Cavernous Fistula Incompletely Occluded by Detachable Balloon.
Kyoung Moon KWAK ; Young Joon KIM ; Tae Hoon KANG ; Jung Nam SUNG ; Hyun Koo LEE ; Maeng Ki CHO
Journal of Korean Neurosurgical Society 1997;26(12):1760-1765
For the treatment of carotid-cavernous fistula, detachable balloon occlusion(DBO) is the method of choice. When it fails, or when the fistula is incompletely occluded, alternative treatment methods include direct surgery and internal carotid artery occlusion at the proximal and distal portion of the fistula. Before ligation or occlusion of the internal carotid artery, however, coil embolization should be considered, as this preserves patent internal carotid artery. The authors used DBO in a 22-year-old male patient with carotid-cavernous fistula which developed after head injury. During the procedures the fistula was partially obstructed by one detachable balloon. In spite of several attempted occlusions with a second balloon, this could not be introduced into the small remnant fistula hole. The second stage of intervention involved embolization with a Guglielmi detachable coil(GDC) ; this was successfully introduced into the partially obstructed fistula, which was thus completely occluded, and the patient's clinical symptoms improved. In this case, GDC emboization was an effective tool for the treatment of carotid-cavernous fistula incompletely occluded by a detachable balloon.
Carotid Artery, Internal
;
Craniocerebral Trauma
;
Embolization, Therapeutic
;
Fistula*
;
Humans
;
Ligation
;
Male
;
Young Adult
6.Mycobacterium intracellulare pulmonary infection accompanied with pleural effusion.
Soo Yeong KWAK ; Sun Youn BAE ; Won Kyoung YUN ; Min Young KIM ; Yoon Jung KIM ; Moon Ki CHOI ; Won Jung KOH
Korean Journal of Medicine 2008;75(4):475-478
Nontuberculous mycobacterial infection is rarely accompanied by pleural involvement. We report a very rare case of Mycobacterium intracellulare pulmonary disease accompanied with pleural effusion. A 76-year-old man was admitted to our hospital because of dyspnea. A chest radiograph and CT showed bilateral bronchiectasis and bronchopneumonia accompanied with right pleural effusion. The fluid was lymphocyte-dominant exudative effusion, and microbiological examinations of the effusion, including staining and culturing, proved negative. However, one month after admission, subsequent cultures of bronchial washing fluid revealed the presence of M. intracellulare. The patient's effusion was gradually resolved with antibiotic treatment, including clarithromycin.
Aged
;
Bronchiectasis
;
Bronchopneumonia
;
Dyspnea
;
Humans
;
Lung Diseases
;
Mycobacterium
;
Mycobacterium avium Complex
;
Mycobacterium avium-intracellulare Infection
;
Pleural Effusion
;
Thorax
7.Prevalence of antibodies to Bartonella henselae and Bartonella quintana in Korean Patients with Lymphadenopathy.
Min Byoung CHAE ; Ji Young LEE ; Yee Gyung KWAK ; Sung Hak PARK ; Hee Jung LIM ; Sang Woo PARK ; Moon Hyun CHUNG ; Mee Kyoung KIM ; Jae Seung KANG
Korean Journal of Infectious Diseases 2002;34(5):305-310
BACKGROUND: Cat scratch disease (CSD) manifests as a self-limiting, regional lymphadenopathy, fever and constitutional symptoms following a cat scratch or close contact with cats. Bartonella henselae is a causative agent of CSD that is globally distributed. In Korea there are no case report of CSD and no reports on the seroprevalence of Bartonella henselae in patients with suspected CSD. In this study the prevalence of antibodies to Bartonella in patients with lymphadenopathies was evaluated. METHODS: We evaluated serological responses of 31 patients (8 male, 23 female) with regional lymphadenopathies. The age of the patients ranged from 6 to 76 years old (mean+/-S.D., 30.6+/-14.3 years). Final diagnoses on the lymphadenopathies were tuberculous lymphadenopathy, Kikuchi's disease, Kawasaki's disease, and viral infection, but considerable cases remained undiagnosed. All sera were examined using MRL Diagnostics Bartonella IgG indirect immunofluorescent antibody (IFA) test kits (MRL Diagnostics, Cypress, California, USA) according to the manufac-turer's instructions. RESULTS: Of the 31 patients, 21 (67.7%) patients showed positive titers of immunoglobulin G (IgG) to B. henselae (1 : 64 or higher). Twelve (38.7%) had IgG titers of 1 : 128 and four (12.9%) had titers of 1 : 256. Among these patients, three patients had a history of close contact with a cat or cat scratch. Twenty patients (64.5%) showed positive reactions against B. quintana. CONCLUSION: This study revealed possible patients with cat scratch disease, but, unlike other countries, Bartonella seropositivity was not closely associated with cat contact. The further studies should be performed in a large number of patients including a control group and be accompanied with culture or polymerase chain reaction of extirpated lymph node.
Aged
;
Animals
;
Antibodies*
;
Bartonella henselae*
;
Bartonella quintana*
;
Bartonella*
;
California
;
Cat-Scratch Disease
;
Cats
;
Cupressus
;
Diagnosis
;
Fever
;
Histiocytic Necrotizing Lymphadenitis
;
Humans
;
Immunoglobulin G
;
Korea
;
Lymph Nodes
;
Lymphatic Diseases*
;
Male
;
Polymerase Chain Reaction
;
Prevalence*
;
Seroepidemiologic Studies
8.The Prevalence of Bartonella henselae Infection in Korean Feral Cats.
Ji Young LEE ; Jae Seung KANG ; Mee Kyoung KIM ; Tae Sook HWANG ; Yee Gyoung KWAK ; Min Byoung CHAE ; Cheol Soon JANG ; Il Kwon KIM ; Dong Bum SEO ; Moon Hyun CHUNG
Korean Journal of Infectious Diseases 2001;33(5):319-324
BACKGROUND: Cat scratch disease (CSD) is an emerging disease worldwide and is mainly caused by Bartonella henselae, a gram-negative bacterium. The most common clinical manifestation is regional lymphadenopathy, though clinical recognition may be difficult, as atypical manifestations occur. The condition can be complicated by neuroretinitis, endocarditis, and sometimes fatal encephalopathy. The reservoir of B. henselae is the cat, and the prevalence rates of B. henselae infection in cat populations range from 4 to 70%. The prevalence of Bartonella infection in Korea has not been studied, thus, in this study Bartonella infection was investigated in cats captured in the Inchon and Ansan areas. METHODS: Twenty wild cats were captured and their livers and spleens were examined by polymerase chain reaction (PCR), bacterial culture, and histopathologically. PCR used two primers: Cat (sense:5'-GAT TCA ATT GGT TTG AA(G/A) GAG GCT-3', antisense:5'-TCA CAT CAC CAG G(A/G)C GTA TTC- 3') and Barto (sense:5'-(C/T) CT TCG TTT CTC TTT CTT CA-3', antisense:5'-AAC CAA CTG AGC TAC AAG CC-3'). Culture was performed by inoculating sliced spleen and liver into the ECV304 cell line and bacterial growth was observed over a period of 3 weeks. If no visible bacterial growth was identified, the presence of bartonella was examined by DNA staining, indirect immunofluorescent staining, and PCR. Liver and spleen were stained with H&E and scrutinized under the light microscope. RESULTS: Nine pairs of culture cells inoculated with liver and spleen were examined by indirect immunofluorescent staining and PCR; no positive case was found. In addition, no positive case was identified by PCR in the liver and spleen specimens of eleven cats. Spleen and liver specimens of eleven cats were examined by light microscopy and none showed granuloma. CONCLUSION: This preliminary study suggests that the Bartonella infection is probably uncommon in the cat population of the Inchon and Ansan areas. Further studies should be undertaken to detail the prevalence of Bartonella infection in other areas and in human.
Animals
;
Bartonella henselae*
;
Bartonella Infections
;
Bartonella*
;
Cat-Scratch Disease
;
Cats*
;
Cell Line
;
DNA
;
Endocarditis
;
Granuloma
;
Gyeonggi-do
;
Humans
;
Incheon
;
Korea
;
Liver
;
Lymphatic Diseases
;
Microscopy
;
Polymerase Chain Reaction
;
Prevalence*
;
Retinitis
;
Spleen
9.The role of methylenetetrahydrofolate reductase C677T polymorphism on the peripheral blood natural killer cell proportion in women with unexplained recurrent miscarriages.
Chan Woo PARK ; Ae Ra HAN ; Joanne KWAK-KIM ; So Yeon PARK ; Jung Yeol HAN ; Mi Kyoung KOONG ; In Ok SONG ; Kwang Moon YANG
Clinical and Experimental Reproductive Medicine 2011;38(3):168-173
OBJECTIVE: To examine the association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and hyperhomocysteinemia in women with unexplained recurrent miscarriages (RM) and to investigate the association between MTHFR genotype variants and alloimmune activation, proportion of peripheral blood natural killer (pbNK) cells. METHODS: A total of 39 patients with a history of two or more unexplained miscarriages were recruited to this study. The controls were women who had a live birth without a history of RM (n=50). The proportion of pbNK cells was measured by flow cytometry. Plasma homocysteine levels and the incidence of the MTHFR variant of the RM and control groups were compared. The proportion of pbNK cells was compared to the MTHFR variants in the RM group. RESULTS: No differences were found between the two groups' mean plasma homocysteine levels (7.6+/-1.5 micromol/L vs. 7.1+/-2.1 micromol/L) or incidence of the MTHFR genotype variant (CC, 35% vs. 33%; CT, 40% vs. 53%; and TT, 25% vs. 14%). In the RM group, individuals with the TT variant (7.7+/-1.1 micromol/L) had higher homocysteine levels than those with the CC and CT variants (7.4+/-1.9 micromol/L and 7.4+/-1.2 micromol/L) and those with the CT variant (19.2+/-8.1%) had a higher proportion of CD3-/CD56+ pbNK cells than those with the CC and TT variants (17.7+/-6.6% and 17.9+/-7. 0%), but the results of both comparisons were statistically insignificant. CONCLUSION: These preliminary results show no difference in plasma homocysteine levels between the RM and control groups or among MTHFR genotype variants in the RM group, which may suggest that the plasma homocysteine level is difficult to use as a predictive marker of RM in the Korean population. A study of a larger number of patients is needed.
Abortion, Habitual
;
Abortion, Spontaneous
;
Female
;
Flow Cytometry
;
Genotype
;
Homocysteine
;
Humans
;
Hyperhomocysteinemia
;
Incidence
;
Killer Cells, Natural
;
Live Birth
;
Methylenetetrahydrofolate Reductase (NADPH2)
;
Plasma
;
Pregnancy
10.TEE-guided Excision of Intravenous Leiomyomatosis with Right Atrium Extension through an Abdominal Approach: A Case Report.
Jae Young KWAK ; Yong Pil CHO ; Hyang Kyoung KIM ; Ki Myung MOON ; Il Seon HWANG ; Tae Won KWON
Journal of the Korean Society for Vascular Surgery 2008;24(1):68-71
Intravenous leiomyomatosis (IVL) is a rare, benign tumor that originates from the uterus. IVL is usually confined to the pelvic venous system, but it travels into the inferior vena cava (IVC) in 10% of cases and even into the heart in 3% of cases. We present a case of successful resection of recurrent IVL with right atrium extension. We used only an abdominal incision and transesophageal echocardiography (TEE) guidance. A 40-year-old female patient visited our hospital with recurrent IVL. She had a history of total abdominal hysterectomy and right salpingo-oophorectomy due to IVL performed one year prior. On computed tomography (CT) and ultrasonography, IVL was found to involve both ovarian veins, the left renal vein, and the IVC extending to the right atrial junction. Using intraoperative TEE monitoring, we could see that IVL was not attached to the vascular wall. After creating a midline abdominal incision, we removed the tumor through the enlarged ovarian vein and ovary. The patient had an uneventful recovery and was discharged home on the ninth postoperative day.
Adult
;
Echocardiography, Transesophageal
;
Female
;
Heart
;
Heart Atria
;
Humans
;
Hysterectomy
;
Leiomyomatosis
;
Ovary
;
Renal Veins
;
Uterus
;
Veins
;
Vena Cava, Inferior