Together, neonatal hepatitis and biliary atresia make up approximately 70 to 80% of the causes of neonatal cholestasis. Biliary atresia must be differentiated from neonatal hepatitis as soon as possible in order to institute early surgical intervention. We performed this study to examine whether the measurement of the serum alpha-fetoprotein (AFP) and thyroxine-binding globulin(TBG) was useful for differentiating these two conditions. Serum AFP levels were measured using enzyme immunoassay in 76 infants with cholestasis and serum TBG levels were measured using radio immunoassay in 30 infants with cholestasis and 23 infants without cholestasis. Serum AFP and TBG concentrations in patients were compared with the normal ranges in infants and were expressed as standard deviation (SD) scores. 52.7% of the patients with neonatal hepatitis showed SD scores of AFP higher than 4.0. By contrast, 14.3% of the patients with biliary atresia showed SD scores of AFP highter than 4.0(p<0.005). The patients with either neonatal hepatitis or biliary atresia had TBG concentrations above the normal ranges, but there was no difference between neonatal hepatitis and biliary atresia. The patients with neonatal hepatitis who recovered from jaundice after 6 months of age or progressed to chronic liver disease of died of the liver disease showed hight serum levels of AFP and TBG than the patients who recovered from jaundice before 6 months of age. In conclusion. SD scores of AFP could be used to differentiate between neonatal heptatis and biliary atresia, and SD scores of AFP and TBG might be used as an indicator of prognosis of neonatal hepatitis.
alpha-Fetoproteins* ; Biliary Atresia* ; Cholestasis ; Hepatitis A ; Hepatitis* ; Humans ; Immunoassay ; Immunoenzyme Techniques ; Infant ; Jaundice ; Liver Diseases ; Prognosis ; Reference Values ; Thyroxine-Binding Globulin*

Septic arthritis in neonates is a rare condition. A failure to make an early diagnosis of septic arthritis in neonates may leave a permanent disability as a result of a delayed treatment. Thus, septic arthritis, requires a prompt diagnosis and a timely treatment especially in this subset of patients. In this case report, we describe our treatment protocol for septic arthritis and concurrent osteomyelitis in the right shoulder of a 28-day-old newborn. Using 2.4 mm wrist arthroscopy, we performed an arthroscopic irrigation and drainage, to remove intra-articular debris and inflammatory tissue, and multiple drilling. We report a satisfactory clinical outcome without any postoperative complications or side effects.
Arthritis, Infectious* ; Arthroscopy ; Clinical Protocols ; Diagnosis ; Drainage ; Early Diagnosis ; Humans ; Infant, Newborn* ; Osteomyelitis ; Postoperative Complications ; Shoulder Joint ; Shoulder* ; Wrist

No abstract available.
Blood Transfusion* ; Female ; Humans

No abstract available.
Thymus Hyperplasia*

Teratocarcinoma is a form of mixed germ cell tumor composed of a mixture of teratoma and embryonal carcinoma. It is rarely found in the brain, but when present it is most commonly found in the pineal region. We investigated a case of primary teratocarcinoma in the pineal region. The patient was a 10 year old boy who had suffered from a bitemporal headache for one month. Brain CT and MRI revealed a rather well defined ovoid heterogenous mass in the pineal gland region, measuring 4.3 x 3.8 x 3.0 cm in size. Microscopically the tumor contained areas of immature teratoma and embryonal carcinoma. Immunohistochemical staining revealed positive reactions for cytokeratin, epithelial membrane antigen, carcinoembryonic antigen, and alpha-fetoprotein in the embryonal carcinoma component.

No abstract available.
Anemia, Aplastic* ; Child* ; Humans ; Immunomodulation*

A 57 year-old patient developed transient blindness and impending syncope whenever he tumed his head to the right side. The angiography showed severe focal luminal narrowing of the right vertebral artery at the level of C5-C6 interspace with head tumed to the right, but showed normal filling of the right vertebral artery in the straight position. The distal cervical portion of the left vertebral artery was hypoplastic We believe that symptoms of this patient are due to the right vertebral artery compression produced by osteophyte formed at uncinate portion of the vertebrae on head tuming to the right. This patient also experienced transient global amnesia for about four hours after the right vertebral arteriography performed with head tumed to the right.
Amnesia, Transient Global* ; Angiography ; Blindness ; Head ; Humans ; Middle Aged ; Osteophyte ; Phenobarbital ; Spine ; Spondylosis* ; Syncope ; Vertebral Artery ; Vertebrobasilar Insufficiency*

No abstract available.
Carcinoma, Basal Cell ; Facial Dermatoses* ; Keratosis, Actinic ; Skin*

No abstract available.
Humans ; Male*

A Case of Fibromuscular dysplasia involoving the left internal carotid and middle cerebral rtery in a previously healthy man is presented. Symptoms were characteristic of cerebral schemia in the territory that the left middle cerbral artery supplies. This case suggests that The fibromuscular dysplasia is one of the causes provoking cerebral infarction.
Arteries ; Cerebral Infarction* ; Equipment and Supplies ; Fibromuscular Dysplasia*