1.Hurthle Cell Tumor of the Thyroid Gland in an Infant: A case report.
Kyoung Ho KIM ; Mi Kyung LEE ; Dong Hwan SHIN ; Tae Seung KIM ; Eui Ho HWANG
Korean Journal of Pathology 1989;23(4):476-481
Hurthle cell tumors are an infrequent neoplasm of the thyroid gland in adults. Hurthle cell tumors represent 4. 5% to 10% of all primary thyroid epithelial neoplasms in the foreign literature. It has been known as Hurthle cell tumor since Ewing was the first to use this term in 1928. Tumor occurring in an infant was described by Symmers(1941) and Morrow(1945). The authors experienced a case of congenital Hurthle cell tumor of the thyroid gland in a 2 months old boy. He was admitted to the pediatric surgical department because of a growing mass in the neck since birth. Ultrasonogram showed a huge lobulated homogenous solid mass with medium level echogenicity in the region of the thyroid gland. Subtotal thyroidectomy of right lobe and total thyroidectomy of left lobe were done. The specimen measures 2x3x1.5 cm and 7x3x3 cm, respectively. It was an encapsulated, yellow gray firm and solid mass. The cut surface was smooth, glistening and homogenous. Microscopicully, the tumor was composed of tightly packed regular follicles lined by polyhedral, cuboidal, large cells with a granular acidophilic cytoplasms. The nuclei are vesicular, usually only a little bit larger than those of normal thyroid cells.
Infant
;
Adult
;
Male
;
Female
;
Humans
2.A study of cisplatin nephrotoxicity.
Young Hee HWANG ; Kyoung A LEE ; Son Moon SHIN ; Young Hoon PARK ; Jeong Ok HAH ; Chun Dong KIM ; Young Hwan LEE
Yeungnam University Journal of Medicine 1992;9(2):327-333
To evaluate the nephrotoxicity of cisplatin, serum levels of sodium, potassium, chloride, calcium, phosphorous, magnesium, BUN, creatinine and creatinine clearance were measured before and after administration of cisplatin in 18 cases of patients with malignant neoplasm. The results were as follows: 1) Serum calcium, magnesium, potassium and BUN levels were changed after cisplatin administration, but those changes were not statistically significant. 2) The mean value of creatinine clearance was not decreased significantly after treatment with cisplatin. 3) Acute renal failure was developed in one case, and four cases of hypocalcemia, hypomagnesemia were also detected after administration of cisplatin.
Acute Kidney Injury
;
Calcium
;
Calcium Chloride
;
Cisplatin*
;
Creatinine
;
Humans
;
Hypocalcemia
;
Magnesium
;
Potassium
;
Sodium
3.Nutmeg liver cardiac cirrhosis caused by constrictive pericarditis.
Kyoung Hwang SHIN ; Hyun Don JOO ; Il Han SONG
The Korean Journal of Internal Medicine 2015;30(6):938-939
No abstract available.
Aged
;
Biopsy
;
Humans
;
Liver Cirrhosis/diagnosis/*etiology/therapy
;
Male
;
Pericarditis, Constrictive/*complications/diagnosis/therapy
;
Tomography, X-Ray Computed
4.Clinical Implication of Plasma Uric Acid Level.
Young Tae SHIN ; Kyoung Kon KIM ; In Cheol HWANG
Korean Journal of Family Medicine 2009;30(9):670-680
The debate over the clinical meaning of plasma uric acid level is still a very hot issue. As the interest in health grows larger in the general public, the number of having a regular health check-up is increasing rapidly. Most of the health care centers routinely check the plasma uric acid level but it is not simple to interpret and explain the appropriate meaning of that. Over the past decade, there have been several studies on clinical implication of plasma uric acid level but the question still remains. However the clinical significance of the results might be different according to the severity of cardiovascular risk among subjects studied, and the findings for correlation with the established risks have enough proof to be applied to clinical practice. Additionally, the uric acid-lowering agents should not be used in general population even though it has reason to be prescribed in a specific high risk patient. Thus, this review seeks to be helpful in clinical practice by examining the preexisting related studies in a different perspective.
Delivery of Health Care
;
Humans
;
Hyperuricemia
;
Plasma
;
Uric Acid
5.A Case of Hypertrophic Cardiomyopathy in Identical Twin.
Wea Kyoung SHIN ; Hae Young LEE ; Hwang Min KIM ; Jae Seung YANG ; Baek Keun LIM ; Jone Soo KIM
Journal of the Korean Pediatric Society 1990;33(10):1399-1405
No abstract available.
Cardiomyopathy, Hypertrophic*
;
Humans
;
Twins, Monozygotic*
6.A Case of Diencephalic Syndrome.
Eun Kyoung JI ; Hye Kyoung YU ; Eun Young HWANG ; Jae Won HUH ; Jae Shin PARK ; Jae Gon MOON
Journal of Korean Society of Pediatric Endocrinology 2000;5(1):137-142
Diencephalic syndrome is a rare cause of failure to thrive in infancy and early childhood. The syndrome is characterized by profound emaciation with normal appetite, loss of cutaneous adipose tissue, hyperactivity, euphoria, and nystagmus. It commonly occurs in association with chiasmatic and hypothalamic gliomas. It has also been described in association with other histologic types. There is the marked increase of serum growth hormone, which may exhibit an inappropriate, even paradoxical response in stimulation test. A male infant of 12 months of age, showed markedly elevated growth hormone but he had failure to thrive findings. Evenly enhanced round mass was seen at suprasella area in brain CT. Its histological findings was "Desmoplastic infantile ganglioglioma", very rare histologic type. Here we report a case of diencephalic syndrome presented by failure to thrive in association with hypothalamic tumors.
Adipose Tissue
;
Appetite
;
Brain
;
Emaciation
;
Euphoria
;
Failure to Thrive
;
Glioma
;
Growth Hormone
;
Humans
;
Hypothalamic Neoplasms
;
Infant
;
Male
7.Spontaneous Bilateral Achilles Tendon Rupture after Local Steroid Injection for Carpal Tunnel Syndrome in a Diabetic Patient: A case report.
Shin Kyoung KIM ; Jong Moon KIM ; Hyun Sik PARK ; Hyun Joon SHIN ; Chan Ho HWANG
Journal of the Korean Academy of Rehabilitation Medicine 2009;33(6):715-717
Achilles tendon injuries are one of the most common tendon injuries in the lower extremities, but spontaneous bilateral achilles tendon rupture without any external force is extremely rare. We present a case of a patient who had spontaneous bilateral achilles tendon rupture related to multiple steroid injections for carpal tunnel syndrome in diabetes. According to this case, we suggest that we should take special precaution to use steroid to the diabetes though it is not applied to the achilles tendon directly.
Achilles Tendon
;
Carpal Tunnel Syndrome
;
Diabetes Mellitus
;
Humans
;
Lower Extremity
;
Rupture
;
Tendon Injuries
8.A Case Report of Takotsubo Cardiomyopathy During Breast Augmentation.
Kyoung Mook LEE ; Youn Hwan KIM ; Jeong Tae KIM ; Won Jung HWANG ; Jin Ho SHIN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2011;38(1):85-88
PURPOSE: Takotsubo cardiomyopathy is a relatively uncommon type of stress-induced cardiomyopathy characterized by transient left ventricular regional wall motion abnormalities. Emotional and physical stresses play a key role in this type of cardiomyopathy in postmenopausal women. The current hypothesis is that the syndrome represents a form of catecholamine surge due to stress or epinephrine-mediated acute myocardial stunning. METHODS: A 44-year-old woman had suffered premature ventricular contraction following a cardiogenic shock during a breast augmentation surgery under enflurane anesthesia and tumescent solution infiltration. She was treated with cardiopulmonary resuscitation at a local clinic. Then she was brought to the Emergency Department of the authors' hospital. RESULTS: The woman's echocardiogram showed an ejection fraction of 20~25% with associated basal hyperkinesis and left ventricular apical ballooning. The patient was admitted to the ICU and required inotropic support for two weeks. The patient's condition dramatically improved, and her ejection fraction returned to 70%. CONCLUSION: It is believed that there were multiple triggering factors of the onset of Takotsubo cardiomyopathy in the woman's social and family history, including infiltration of a large volume of the tumescent solution and VPCs induced by enflurane anesthesia without premedication. The importance of careful history-taking, careful pre-operative consultation on psychological suffering especially for breast surgery, premedication before surgery, patient reassurance, and post-operative psychosocial and emotional assistance was again seen in this case.
Adult
;
Anesthesia
;
Breast
;
Cardiomyopathies
;
Cardiopulmonary Resuscitation
;
Emergencies
;
Enflurane
;
Female
;
Humans
;
Hyperkinesis
;
Premedication
;
Shock, Cardiogenic
;
Stress, Psychological
;
Takotsubo Cardiomyopathy
;
Ventricular Premature Complexes
9.Alteration of Cognitive Function in Mild Traumatic Brain Injury Patients Grouped by Subjective Depression.
Heesung HWANG ; Kyoung Sae NA ; Shin Gyeom KIM ; Soyoung Irene LEE ; Han Yong JUNG
Journal of Korean Neuropsychiatric Association 2012;51(5):300-305
OBJECTIVES: To examine the association of subjective depressive symptoms and cognitive dysfunction in patients with mild traumatic brain injury (mTBI). METHODS: 36 patients with mTBI without structural abnormality in the brain imaging study were recruited. Participants were subdivided into two groups by a cutoff score of 70T in the Beck Depression Inventory (BDI). Cognitive functions including intelligence, memory, and executive function were significantly lower in the <70T group compared to the > or =70T group. In addition, BDI scores were negatively correlated with performances in most of the neuropsychological tests. RESULTS: Patients group who scored 70T or more in the BDI showed significantly lower scores in most items of the neuropsychological tests. CONCLUSION: High subjective depression is associated with low neuropsychological performance in mTBI.
Brain Injuries
;
Depression
;
Executive Function
;
Humans
;
Intelligence
;
Memory
;
Neuroimaging
10.A Case of Congenital Central Hypoventilation Syndrome with PHOX2B Gene Mutation in a Korean Neonate.
Kyoung Ah KWON ; Su Eun PARK ; Shin Yun BYUN ; Shine Young KIM ; Sang Hyoun HWANG
Journal of Korean Medical Science 2010;25(8):1237-1240
Congenital central hypoventilation syndrome (CCHS) is a life-threatening disorder with apnea and cyanosis during sleep requiring immediate endotracheal intubation during the first day of life. The PHOX2B gene has been identified as the major gene involved in CCHS. This is the first report of a Korean neonate with CCHS confirmed to have a PHOX2B mutation with expanded alleles containing 20 polyalanine repeats that is a relatively small number compared to previous cases. The patient required intermittent ventilator support during sleep only and did not suffer from any other disorders of the autonomic nerve system. He consistently needs ventilator support during sleep and remains alive. Analysis of PHOX2B gene is useful for diagnosis and appropriate therapeutic intervention of CCHS patients.
Alleles
;
Asian Continental Ancestry Group/*genetics
;
Genotype
;
Homeodomain Proteins/*genetics
;
Humans
;
Hypoventilation/congenital/*genetics
;
Infant, Newborn
;
Male
;
Mutation
;
Peptides/genetics
;
Republic of Korea
;
Sequence Analysis, DNA
;
Transcription Factors/*genetics
;
Ventilators, Mechanical