The urban population of our country is rapidly increasing due to many factors of social structure, and sociologists are predicting that the increase rate of the urban population will be over 50% in 1980's. Above all, the population of the capital city of Seoul, is at present more than four millions. Such centering of people in cities, together with the improvement of the standards of living, caused rapid increase in the amount of fuel consumption, and this consumption of fuels became one of the primary sources of the air pollution in cities. Moreover, the heavy traffic, construction of many tall buildings, and the increasing number of new factories due to the industrial development-all these are contributing to make the matter of air pollution worse and in worse in the Metropolitan, whose geographical location is quite unfavorable considered from the view point of air pollution. Most homes in Seoul use briquet as fuel, while oils are used in tall buildings. The CO, SO2, and smoke that come from burning of these furls are a great threat to the health of the urban population. With the purpose of examining the influence of air pollution upon the public health, written inquiries were made upon respiratory diseases, and the carboxyhemoglobin saturation in the blood was measured to determine whether the air pollution may affect the health of the urban population. Method of Health Examination. (1) Investigation of Respiratory Diseases. Patients' records were examined to finure out the monthly ambulance rate of respiratory patients to the total number of patients treated. On the other hand, by using the questionnaire form approved by the Medical Research Council's Committee on Research into Chronic Bronchitis, investigators interviewed the examinees and inquired into the respiratory symptoms. (2) Measuring of Carboxyhemoglobin Saturation. From the ear lobe of the examinees, with the use of the melangeur for the white blood cell counting, blood was taken, and after diluting it ten times with 0.1% Na2Co3, again diulting it 20 times with 0.5% Na2 CO3, its absorbancy was measured. The following results are obtained from the investigation. (1) It was found out that 7.7% of the total patients under treatment were suffering from upper respiratory infection, acute or chronic bronchitis. bronchial asthma. Pulmonary emphysema and bronchiectasis. of them all, patients with upper respiratory infection numbered the greatest with 4.8% and patients with acute or chronic bronchitis the next with 2.1%, and their monthly ambulance rate was high form December to February during the winter, and form April to May and Form September to October during the changeable seasons. (2) The daily ambulance rate of respiratory patients, it was revealed, had a close connection with the concentration of So2 and Co2 in the air. (3) It was found out that men were more subject to respiratory disease than women, and both men and women were more liable to the diseases with the advancing of age. (4)People living at Choong-ku with the heavy traffic and in the industrial zones of Yeundungpo had high frequency of respiratory symptoms. (5) Considered from the view point of occupations, high frequency was found among those without job, with jobs unknown, merchants and industrial workers, whose social status was rather low and traffic policemen who were always exposed to the exhaust gas of cars. As for women, the frequency was detected in the order of those from high to low, housewives who were exposed to briquet gas, women with jobs unknown, women without jobs, whose social status was low. (6) Ex-smokers rallier than smokers, of both sexes, had higher frequency. As for moll, heavy smokers had high frequency, while in women light smokers had rather high frequence which was presumed to be due to their average old age. (7) Men's average of carboxyhemoglobin saturation was 9.48%, while women's was 11.3%, higher than men's. (p<0.05). Age meant no difference in the case of men, but as for women, the saturation was remarkably high between the ages from 20 to 60. (8) No regional difference was detected in the carboxhemoglobin saturation. (9) The carboxyhemoglobin saturation was found, in the case of men, in the order of office workers, traffic policemen, students, the unemployed, merchants and industrial worker; drivers and as for women, the order was housewives, office worker merchants and industrial workers. (10) No significant correlation was found between the carboxyhemoglobin saturation and the concentration of Co detected in kitchens, or between the carboxyhemoglobin saturation 2nd the passing of time after exposure to briquet gas. No difference of carboxyhemoglobin saturation was detected between smokers and non-smokers, and the degrees of smoking: only, significant negative correlation was found between the passing of time after smoking and the carboxyhemoglobin saturation. It is true that air pollution causes or aggravates the respiratory diseases, increases the carboxyhemoglobin saturation in the blood, but what seems to be more hazardous to the health is tile air polluted by the briquet gas in the kitchens and on-dol rooms rather than the atmospheric pollution.
Air Pollution* ; Ambulances ; Asthma ; Bronchiectasis ; Bronchitis, Chronic ; Burns ; Carboxyhemoglobin ; Ear ; Epidemiologic Studies* ; Female ; Hand ; Humans ; Leukocyte Count ; Male ; Occupations ; Oils ; Public Health ; Pulmonary Emphysema ; Surveys and Questionnaires ; Research Personnel ; Seasons ; Seoul ; Smoke ; Smoking ; Urban Population*

Purpose of this study is to find out proper means of estimating the urinary mercury excretion the normal individuals. Whole void volume was collected every 2 hours beginning from 6 o'clock in the morning until 6 o'clock next morning. Mercury excretion in each urine specimen was measured by NIOSH recommended dithizone colorimetric method (Method No. : P & CAM 145). Urinary concentration of mercury was adjusted by two means : specific gravity of 1.024 and a gram of creatinine excretion per liter of urine comparing the data with the unadjusted ones. Mercury excretion in 24-hour urine specimen was calculated by adding the amounts measured with the hourly collected specimens of each individual. Statistical analysis of the urinary mercury excretion revealed the following results : 1. Frequency distribution curve of mercury excreted in urine of hourly specimens was best fitted to power function expressed in the form of y=ax(b), Adjustment of the urinary mercury concentration by creatinine excretion was shown to be superior (y=1674x(-1.52)), r(2)=0.95) over nonadjustment(y=2702x(-1.57)), r(2)=0.92) and adjustment by specific gravity of 1.024(y=4535x(-1.66), r(2)=0.93). 2. Both log-transformed mercury excretion in hourly voided specimens and mercury excretion itself in 24 hour specimens showed the normal distributions. 3. The frequency distribution of mercury adjusting the urinary concentration of mercury by creatinine excretion was best fitted to a theoretical normal distribution with the sample means and excretion was best fitted to a theoretical normal distribution with the sample means and standard deviation than those unadjusted or adjusted with specific gravity of 1,024. 4. Average urinary mercury excretions in 24-hour urine specimen in an individual were as follows : a) Unadjusted urinary mercury excretions. mean and standard deviation :18.6+/-13.68 microgramHg/liter. median : 16.0 microgramHg/liter. range : 0.0-55.10 microgramHg/liter. b) Adjusted with specific gravity. mean : 20.7+/-11.76 microgramHg/liter x 0.024/(S.G.-1.000). median : 20.7 microgramHg/liter x 0.024/(S.G.-1.000). range : 0.0-52.9 microgramHg/liter x 0.024/(S.G.-1.000). c) Adjuested with creatinine excretion. mean and standard deviation : 10.5+/-6.98 microgramHg/g creatinine/liter. median : 9.4 microgramHg/g creatinine/liter. range : 0.0-26.7 microgramHg/g creatinine/liter. 5. No statistically significant differences were found between means calculated from 24-hour urine specimens and those from hourly specimens transformed into logarithmic values. (P<0.05).
Creatinine ; Dithizone ; Gravitation ; National Institute for Occupational Safety and Health (U.S.) ; Specific Gravity

Production of free radicals of superoxide anion in tissues by cadmium, activities of superoxide dismutase and catalase to protect tissue damages caused by the free radicals and ATPase that plays an important role in energy metabolism at cellular level were investigated. Experiments in viro were conducted with liver, kidney and testicle tissue homogenates of rats adding 0.05~0.50 mM cadmium chloride, and in vivo experiments administering single dose of 5mg of cadmium/kg of body weight in 0.1% cadmium chloride solution intraperitoneally 48 hours prior to evisceration. Production of superoxide radicals in liver and testicle increased with addition of cadmium in vitro, but not in kidney. In vivo experiments, however superoxide radicals slightly increased in liver and kidney but not in testicle. Superoxide dismutase (Cu, Zn-SOD and Mn-SOD), catalase and ATPase (total, (Mg++)- & (Na+)- (K+)-) activity decreased in the presence of cadmium in dose dependent manner. Reduction of these enzyme activities varied not only with dosage of cadmium but also with type of tissue and between in vitro and in vivo experiment.
Adenosine Triphosphatases* ; Animals ; Body Weight ; Cadmium Chloride ; Cadmium* ; Catalase* ; Energy Metabolism ; Free Radicals ; Kidney* ; Liver* ; Rats* ; Superoxide Dismutase* ; Superoxides* ; Testis*

No abstract available.
Adolescent* ; Child* ; Humans

This study was conducted to find out the most suitable weight-height index out of the weight/height(p)-type indices that could be used for the evaluation of nutritional status in an epidemiological survey and for the screening of the obesity. The subjects were chosen randomly, 2,182 males and 719 females from college students and office workers in Seoul districts. The 'best' power-type weight-height index for Korean men and women of all ages from 16 to 59 was found to be weight-height(1.54) for males and weight-height(1.42) for females. Weight-height(2)(Kaup index), however, was the best suited weight-height index for each age group of both sexes except that relative weight (weight-height) was considered to be desirable to apply for males of teen-aged and of over fifties and for females of over forties of age. Normal ranges of Kaup index values for males and females of each age group were presented in tables 5 and 6. These findings suggest that Korean are generally leaner than other ethnic groups of the same sex and age.
Ethnic Groups ; Female ; Humans ; Male ; Mass Screening ; Nutritional Status* ; Obesity ; Reference Values ; Seoul

In order to evaluate the health hazard due to organ orphosphorus insecticides, we measured the blood cholinesterase activity and urinary para-nitrophenol among 56 exposed subjects. They are orchard workers, rice plant workers and smithion factory workers. The clinical symptoms were also checked by physicians. We also measured the blood cholinesterase activity and urinary para-nitrophenol excretion of 20 urban people and 15 rural people who had never been exposed to organophosphorus insecticides in order to compare them according to age, sex and geographical differences. And these results were also compared with those of exposed groups. The results obtained were as follows. 1. The normal plasma cholinesterase activity and cell cholinesterase activity were 0.861+/-0.148 delta pH/hr and 0.822+/-0.154 delta pH/hr. And normal para-nitrophenol in urine was 1.21+/-0.52 mg/liter. 2. No significant difference was existed in blood cholinesterase activities and urinary para-nitrophenol excretion according to sex, age and geographical difference. 3. The plasma cholinesterase activity and cell cholinesterase activity of orchard workers, rice plant workers and smithion factory workers were 0.682+/-0.189 delta pH/hr, 0.775+/-0.160 delta pH/hr, 0.754+/-0.123 delta pH/hr and 0.691+/-0.082 delta pH/hr, 0.756+/-0.117delta pH/hr. And significant decreases in blood cholinesterase activities were existed among orchard workers and smithion factory workers compared with control group. 4. The urinary para-nitrophenol excretions of orchard workers, rice plant workers and smithion factory workers were 1.33+/-0.66 mg/liter, 1.19+/-0.88mg/liter and 1.37+/-0.67mg/liter and there were no significant difference between exposed groups and control group. 5. The clinical symptoms complained during and after organophosphorus insecticides exposure were frequently ranked by headache (67.7%) and vertigo (64.5%) and muscular ataxia and weakness (51.6%).
Ataxia ; Cholinesterases* ; Headache ; Insecticides* ; Plants ; Plasma ; Vertigo

By evaluating the health status by Cornell Medical Index in conjunction with their academic grade, we attempted to find out whether any health condition may affect on their academic carrier. CMI health questionnaire was filled out by student and matched with one's own academic score of the previous year. Academic score was classified into 5 grades: excellent, very good, good, fair and poor. Difference in number of questions between sections was corrected by standard score method with means of 50 and standard deviation of 10. Differences in number of "yes" answers between sections and between groups of students in each grade were statistically tested by two-way variance analysis method. On the other hand, influence of neuropsychiatric factors (section M-R) on the academic carrier was analyzed by X2-test with Fukamachi's classification. The following were the results obtained in this study : 1) Number of "yes" answers in sections related to mood and feeling pattern(section M-R) were appeared to be influential to academic carrier in male students, but not in female students. 2) Generally speaking, in groups of higher academic grade, number of "yes" answers in each section was on an average 50 or less, and in groups of lower academic grade, the number was 50 or more depending on sections. 3)Number of "yes" answers between sections and between groups in each academic grade were significantly different both in male and female college students. 4) It was noteworthy that data obtained from CMI questionnaire might be variable subjective by examines with some factors at the time of administration.
Classification ; Cornell Medical Index* ; Female ; Hand ; Humans ; Male ; Surveys and Questionnaires

Dose-response relationship among blood cadmium concentrations, catalase and superoxide dismutase activities were studied with acutely intoxicated rats by cadmium. The Sprague-Dawley male rats to which single dose of 1-32 mg/kg CdCl2 were administered into peritoneal cavity were sacrificed by decapitation at 3-36 hours after the administration. Cadmium concentrations in blood increased significantly with dose of CdCl2 administered and reached peak level at 3 hours later. Catalase activities in rats' tests were not correlated with exposure time elapsed after the administration in rats to which 1-2 mg/kg of CdCl2 were administered, but they showed linear relationship with time in groups to which 4-32 mg/kg of CdCl2 were administered. Cu, Zn-SOD activities in tests of acutely intoxicated rats by cadmium were not altered either by dosage or by time elapsed after the administration. Mn-SOD activities in the tests were also not influenced by dosage of 1-2 mg/kg CdCl2, but remarkably inactivated by dosage of 4-32 mg/kg CdCl2 with time elapsed after the administration. Neither catalase, Cu, Zn-SOD nor Mn-SOD activities of tests were correlated with blood cadmium concentrations in acutely intoxicated rats by cadmium.
Animals ; Cadmium Chloride ; Cadmium* ; Catalase* ; Decapitation ; Humans ; Male ; Peritoneal Cavity ; Rats* ; Rats, Sprague-Dawley ; Superoxide Dismutase* ; Superoxides* ; Testis*

In order to designate a status necessary for establishment of preventive measures and guidelines of health education against hepatitis B in the course of secondary school education, knowledge and practice toward hepatitis B virus infection was surveyed by a questionnaire method on total of 4,855 college entrants in the academic year of 1987 and analyzed the data collected using IBM PC(Trigem 88-II) with SAS package program. About two percent of college entrants had past history of HBV infections not showing any difference between both sexes and geographical regions. About one third(33.7%) of total students had tested hepatitis B surface antigen(HBsAg), only 4% had tested hepatitis B surface antibody(HBsAb) and vaccination rate amounted to 24.6%, one fourth of total subjects. Both serological tests and vaccination were most commonly performed during adolescence, showing higher rates in female students than in male students. The rates also seemed to be higher in those from urban cities than those from rural cities. Students who had acquired correct knowledge that hepatitis B was infected by virus were amounted to 78.5% of college entrants, and remaining 21.5% had misunderstood that rickettsia, bacteria, fungi or parasites were casual agents. Female students were better aware of the causal agents than male students but there was no difference between places of growth. As for mode of transmission of HBV, 51.5% of male students and 47.7% of female students had correct knowledge. A very few student had known that fact that HBV was transmitted by body fluids such as tear (6.9%), nasal discharge(10.1%) and semen or vaginal secretion(19.2%) and majority(75%) of students had misunderstood that hepatitis B virus would be transmitted per os through food ingestion. Approximately one half(48.9%) of college entrants had correctly whom to be vaccinated. Approximately one half of the students knew that hepatoma(57.8%) and liver cirrhosis(57.4%) might complicate with hepatitis B virus infection, whereas 12.0% of the students responded that bronchitis was one of the complications of hepatitis B infection. In summary of the above results, we highly recommend that health education program for eradication of hepatitis B virus infection should be introduced in curricula of secondary school education in this country.
Adolescent ; Bacteria ; Body Fluids ; Bronchitis ; Curriculum ; Eating ; Education ; Female ; Fungi ; Health Education ; Hepatitis B virus ; Hepatitis B* ; Hepatitis* ; Humans ; Liver ; Male ; Parasites ; Surveys and Questionnaires ; Rickettsia ; Semen ; Serologic Tests ; Tears ; Vaccination

On 6 healthy adult males aged 20-30 years, oxygen pulse was observed during carrying sand bags weighting 10, 20 and 30kg on a level treadmill running with speeds of 3,4 and 5 km/hr. The results obtained were as follows. 1. Oxygen pulse during load carrying on a level treadmill was proportionately increased with an increase of work load, average oxygen uptake per minute. Regression equation of oxygen pulse (y: ml/beat) on the average oxygen uptake (x:l/min) required for each grade of work was expressed as y=3.34x + 5.99, sy.x=0.858. 2. Oxygen pulse reached the highest value 2-5 minutes after the start of load carrying, and thereafter it decreased gradually to some extend as the load carrying was continued. Rate of decrease in the oxygen pulse was gerater in lighter works. 3. In lighter works requiring less than 2.0 l/min of oxygen uptake, oxygen pulse was larger in case of carrying a losd by embrace, in both hands and on head than on back or on shoulder.
Adult ; Hand ; Head ; Humans ; Male ; Oxygen* ; Running ; Shoulder ; Silicon Dioxide