1.Correlation between Apoptosis and Proliferative Activity in Squamous Cell Neoplasia of Uterine Cervix.
Korean Journal of Obstetrics and Gynecology 1999;42(1):98-103
OBJECTIVE: Quantitative analysis of both apoptosis and proliferation should provide important insight into tumor biology. The aim of this study is to clarify the significance of apoptosis in the progression of uterine cervical neoplasia, including cervical intraepithelial neoplasia, and microinvasive and invasive squamous cell carcinoma categories. in relation to cell proliferation. METHODS:: Forty five cases of cervical intraepithelial neopasia. 10 of microinvasive carcinoma, and 10 of invasive squamous cell carcinoma were examined using formalin fixed and paraffin embedded samples. The TdT mediated dUTP-biotin nick end labelling(TUNEL) method for apoptotic cells, and Ki-67 and Topo-II immunojhistochemistry for proliferating activity were performed. RESULTS: Apoptotic and proliferative indices, calculated by counting positive nuclei among 1,000 nuclei of cancer cells, should significant positive correlation with histological malignancy grading in CIN and tumor cell invasion into stroma, and showed also significant positive correlation between them. CONCLUSION: These findings suggest that apoptosis in cervical neoplasia may be closely related to tumor cell differentiation and progression.
Apoptosis*
;
Biology
;
Carcinoma, Squamous Cell
;
Cell Differentiation
;
Cell Proliferation
;
Cervical Intraepithelial Neoplasia
;
Cervix Uteri*
;
Female
;
Formaldehyde
;
Paraffin
2.The study of head-shaking nystagmus in peripheral vestibular disorders.
Sang Cheol LEE ; Kyong Myong CHON
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(3):458-476
No abstract available.
3.Primary Reading Epilepsy: A Case Report.
Joo Han KIM ; Choong Kyong LEE
Journal of the Korean Neurological Association 1984;2(1):71-72
Reading epilepsy, a form of reflex epilepsy or sensory precipitated epilesy, is known as the most frequent type of language induced epilepsy. Since Bickford presented 6 cases of reading epilepsy for the first time, about 50 cases of primary reading epilepsy have been reported. We present a case of primary reading epilepsy which is confirmed by clinical features and EEG, with a brief review of literature.
Electroencephalography
;
Epilepsy
;
Epilepsy, Reflex*
4.Acute effects of cigarrette smoking on the microcirculation of the skin of the palm the cheek and the pretibial region.
Jae Seung LEE ; Kyong Won MINN ; Jae Ho YU
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(2):258-264
No abstract available.
Cheek*
;
Microcirculation*
;
Skin*
;
Smoke*
;
Smoking*
5.Variable complementary combined radiologic imaging methods for breast diseases
Ki Keun OH ; Kyong Sik LEE ; Seing Kook SOHN
Journal of the Korean Radiological Society 1985;21(2):223-236
Radiographic examination of the breast has been so improved that it became a routine complement to physicalexamination. From November 1, 1983 through Sept.30, 1984, 684 patient with complaints of various breast problemwere examined by low-dose film mammography at Yong Done Hospital, Yonesei University. Among them, a comparativestudies, independently conducted physical examination, 97 cases of film mammography, 35 cases of ultrasoundmammography, 16 cases of aspiration cytology, and 3 cases of galactography were performed for our pathologicallyproven 98 cases of breast disease. Combined and complementary studies for breast diseases were analyzed in 37proven cases and authors found that specificity of those combined immediate complementary study techniques forbreast disease were 94% under colose cooperation with surgeon in Yong Dong Hospital, Yonsei University.
Breast Diseases
;
Breast
;
Complement System Proteins
;
Humans
;
Mammography
;
Methods
;
Physical Examination
;
Sensitivity and Specificity
6.Sympathetic skin response in diabetes mellitus.
In Sung LEE ; Hee Sang KIM ; Kyong Hoi AHN
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(2):165-176
No abstract available.
Diabetes Mellitus*
;
Skin*
7.Effects of hyaluronic acid on experimental ear drum perferations.
Dong Hoon LEE ; Eui Kyung GOH ; Kyong Myong CHON
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):862-871
No abstract available.
Ear*
;
Hyaluronic Acid*
8.The role of mammography on breast cancer patients in a hospital setting.
Kyong Po LEE ; Suck Joon HONG ; Ki Keun OH ; Kyong Sik LEE
Yonsei Medical Journal 1990;31(1):49-52
From Oct. 1, 1983 to May 31, 1988, 6198 mammograms were taken and 443 mastectomies were performed at the Yonsei University Hospital, Seoul, Korea. Of these, 191 cases had preoperative mammography performed prior to surgery (study group) and 252 cases underwent mastectomies without preoperative mammography (control group). There were no significant differences between the two groups in pathological stages, axillary lymph node metastasis and size of the tumor, suggesting that little benefit is derived from the preoperative mammography in the hospital setting. However, there were a number of other findings, including a 14% incidence of multiple foci and localization of non-palpable cancer in 3% of cases, that could help us to make therapeutic plans and strategies for these patients.
Breast Neoplasms/pathology/*radiography/surgery
;
Female
;
Hospitalization
;
Human
;
Lymphatic Metastasis
;
*Mammography
;
Preoperative Care
;
Prospective Studies
9.A Case of Perinephric Abscess Treated by Percutaneous Drainage.
Kyong Yun PARK ; Ji Ung KANG ; O Kyong LEE
Journal of the Korean Society of Pediatric Nephrology 2006;10(1):72-76
Perinephric abscess is an accumulation of pus in the perinephric space, the area anatomically defined between the kidney and Gerota's fascia. Gram negative organisms are the most prevalent bacterial species found in perinephric abscess. Fever, flank pain, vomiting and abdominal mass are the usual presenting complaints. But with its insidious onset, variable symptoms and rare frequency in children, perinephric abscess has been a major diagnostic problem, leading to delayed diagnosis and inappropriate treatment, which increase the rate of complication and mortality. Clinical diagnosis of perinephric abscess is difficult but must always be considered in children with a febrile septicemic illness. For appropriate treatment, early detection is very important, and either ultrasonography or computed tomography(CT) facilitates the diagnosis and establishment of treatment method. We experienced a case of left perinephric abscess treated by percutaneous drainage in a 1-year 7-month old boy. Review of literature was made briefly.
Abscess*
;
Child
;
Delayed Diagnosis
;
Diagnosis
;
Drainage*
;
Fascia
;
Fever
;
Flank Pain
;
Humans
;
Infant
;
Kidney
;
Male
;
Mortality
;
Suppuration
;
Ultrasonography
;
Vomiting
10.Epidemiologic and Clinical Study of Mucocutaneous Lymphnode Syndrome in Korea.
Du Bong LEE ; Kyong Su LEE ; Byung Churl LEE ; Ik Jun LEE
Journal of the Korean Pediatric Society 1982;25(10):977-993
No abstract available.
Korea*