1.Clinical application of APR score in the detection of neonatal infections; comparison of fullterm and premature.
Sei Joong KO ; Sang Mi HA ; Mi Kyeung LEE ; Soon Il LEE
Journal of the Korean Pediatric Society 1992;35(12):1674-1682
No abstract available.
2.Statistical Analysis of Death Cases in Pediatric Ward.
Kui Ae JANG ; Kyeung Bae PARK ; Jae Ock PARK ; Chang Hwi KIM ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1990;33(1):1-9
No abstract available.
3.The Relationship of Coping Style and Psychological Distress in the Survivors of Sampoong Accident.
Yun Kyeung CHOI ; Min Soo LEE ; Joon Sang LEE ; Dong Kyun SHIN
Journal of Korean Neuropsychiatric Association 1997;36(4):612-619
Although the same traumatic stress was experienced, the presenting symptoms and their severity might be different. The difference could be associated with the coping style. Thus we were interested in which coping style is more efficient in dealing with stress. Among the 624 survivors of Sampoong Accident we selected active coping group(n=67) and passive coping group(n=63) using the Ways of Coping Checklist. These two groups were compared on scores in Beck Depression Inventory, State-Trait Anxiety Inventory, Impact of Event Scale, MMPI, and 16 Personality Factor Questionnaire. The passive coping group reported that they were more anxious and depressive, and they showed more intrusive thought about traumatic stress, denial, and vulnerable factors of personality than active coping group. These results suggest that active coping style such as problem-focused coping and seeking social supports is more efficient and successful in case as Sampoong Accident. Therefore, for the survivors of extremely traumatic accident, training of active coping skills can be helpful for rehabilitation and adaptation in everyday life.
Adaptation, Psychological
;
Anxiety
;
Checklist
;
Denial (Psychology)
;
Depression
;
Humans
;
MMPI
;
Surveys and Questionnaires
;
Rehabilitation
;
Survivors*
4.Moyamoya-Like Vasculopathy in Neurosarcoidosis.
Jun Kyeung KO ; Sang Weon LEE ; Chang Hwa CHOI
Journal of Korean Neurosurgical Society 2009;45(1):50-52
A 31-year-old man presented with dull headache and memory disturbance lasting for one week. Computed tomographic scans revealed acute hydrocephalus. The cerebrospinal fluid contained 53 leukocytes/mm3, with a mononuclear preponderance and no erythrocytes. Magnetic resonance imaging revealed hydrocephalus and leptomeningeal enhancement. Magnetic resonance angiography and digital subtraction angiography showed supraclinoid occlusion of the right internal carotid artery, which resembled unilateral moyamoya disease. Neuroendoscopic biopsy of a lesion in the septum pellucidum revealed noncaseating granulomas, which was consistent with sarcoidosis. The patient was successfully managed with intravenous methylprednisolone and ventriculoperitoneal shunting. To our knowledge, this is the first case of moyamoya-like vasculopathy associated with neurosarcoidosis.
Adult
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Angiography, Digital Subtraction
;
Biopsy
;
Carotid Artery, Internal
;
Central Nervous System Diseases
;
Erythrocytes
;
Granuloma
;
Headache
;
Humans
;
Hydrocephalus
;
Magnetic Resonance Angiography
;
Magnetic Resonance Imaging
;
Memory
;
Methylprednisolone
;
Moyamoya Disease
;
Sarcoidosis
;
Septum Pellucidum
;
Ventriculoperitoneal Shunt
5.Coiling of Middle Cerebral Artery Bifurcation Aneurysms : Clinical and Angiographic Outcomes.
Jung Hwan LEE ; Jun Kyeung KO ; Sang Weon LEE ; Tae Hong LEE ; Chang Hwa CHOI
Korean Journal of Cerebrovascular Surgery 2008;10(3):411-418
OBJECTIVE: The anatomy of middle cerebral artery (MCA) bifurcation aneurysms has been noted to be unfavorable for endovascular treatment. Our purpose was to analyze the clinical and angiographic results of coiling of the MCA bifurcation aneurysms. METHODS: From January 2004 to April 2007, 26 patients harboring 29 MCA bifurcation aneurysms were treated with coils. Of these patients, 16 had subarachnoid hemorrhages (SAH). The bleeding source was a ruptured MCA bifurcation aneurysm in 11 patients and a ruptured aneurysm in a different location in 5 patients, respectively. Treatment-related complications, clinical outcomes, and postprocedural and follow-up angiography results were retrospectively evaluated. RESULTS: 29 MCA bifurcation aneurysms (11 ruptured, 18 unruptured) were occluded with coils in 26 patients. Occlusion was complete for 24 (82.8%) of the 29 aneurysms, incomplete for 3 (10.3%), and partial for 2 (6.9%) aneurysms. Procedural complications included thromboembolism in 6, a small nonocclusive thrombus formation in 1, and intraprocedural aneurysmal rupture in 1. All of symptomatic complications were thromboembolic events that occurred 3 patients with unruptured aneurysm and they discharged with moderate disability state. Follow-up angiograms were available on 16 patients with 18 aneurysms and 1 patient with an initial complete occlusion had a slight neck recanalization. CONCLUSION: Coiling of MCA bifurcation aneurysm could be achieved without treatment-induced neurologic deficit in 88.5% (23/26) of the patients while at the same time obtaining favorable anatomic results. Improvements in device technology and technique will certainly greatly increase the safety of coiling of MCA bifurcation aneurysm, widening its indications.
Aneurysm
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Aneurysm, Ruptured
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Angiography
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Intracranial Aneurysm
;
Middle Cerebral Artery
;
Neck
;
Neurologic Manifestations
;
Retrospective Studies
;
Rupture
;
Subarachnoid Hemorrhage
;
Thromboembolism
;
Thrombosis
6.Anti-Intrusion Effect of Lorazepam: An Experimental Study.
Hong Seock LEE ; Heung Pyo LEE ; Sang Kyu LEE ; Yong Ku KIM ; Yun Kyeung CHOI
Psychiatry Investigation 2013;10(3):273-280
OBJECTIVE: Easy triggering of trauma-related episodic memory fragments caused by perceptual cues is tied to strong perceptual priming in the implicit memory system. And among benzodiazepines, only lorazepam has been consistently reported to have an atypical suppression effect on perceptual priming processes. The aim of this study was to investigate the effects of single doses of lorazepam, diazepam, and a placebo on intrusive memories after exposure to a distressing videotape and to explore whether the anti-intrusive effect of lorazepam is acquired as a result of the suppression of perceptual but not conceptual priming processes. METHODS: Under prospective, randomized, and double-blind conditions, we compared the anti-intrusion effect of a single dose of lorazepam (n=22) with that of diazepam (n=22) and a placebo (n=21) in young healthy Korean college students following exposure to a traumatic videotape. RESULTS: We present the first finding for an anti-intrusion effect of lorazepam. One day after the medication, lorazepam, rather than diazepam or the placebo, significantly reduced the extent of intrusion and data-driven processing of the traumatic information. There were no differences among the three conditions in state anxiety, depression, and an arousal scale throughout the experiment. CONCLUSION: Results from this study suggest the possibility of lorazepam as a candidate anti-intrusion drug, as well as the cautious use of diazepam in the treatment of PTSD patients. The anti-intrusive effect of lorazepam is directly related to its atypical inhibitory effect on implicit perceptual priming processes. The present study provides support for the enhanced perceptual priming hypothesis of PTSD.
Benzodiazepines
;
Cues
;
Diazepam
;
Humans
;
Lorazepam*
;
Memory
;
Memory, Episodic
;
Prospective Studies
;
Stress Disorders, Post-Traumatic
;
Videotape Recording
7.The Clinical Characteristics of Mycoplasmal Pneumonia in Adults.
Jin Ho KIM ; Doo Seop MOON ; Dong Suck LEE ; Ik Soo PARK ; Kyeung Sang LEE ; Ho Joo YOON ; Dong Ho SHIN ; Sung Soo PARK ; Jung Hee LEE
Tuberculosis and Respiratory Diseases 1995;42(2):175-183
BACKGROUND: The incidence of mycoplasmal pneumonia is predominantly at childhood and early adulthood, but in adults, its incidence is low and its symptoms and physical findings are nonspecific. The definite diagnosis of M. pneumoniae pneumonia can be made by sputum culture, but requires several weeks for positive results, and the early diagnosis must initially be based on the serologic tests and appropriate clinical findings. Thus, we evaluated the clinical aspects of M. pneumoniae pneumonia in the adults patients. METHOD: Among the admitted patients due to pneumonia, the definite diagnosis is anti-M. pneumoniae antibody titer of > 1:40 and a single cold agglutinin titer of > 1:64. The presumptive diagnosis is anti-M. pneumoniae antibody titer of > 1:40 or a single cold agglutinin titer of > 1:64 and the clinical characteristics or chest X-ray findings are compatible with M. pneumoniae pneumonia. We studied the age and sex distribution, seasonal distribution, clinical symptoms, physical findings, serologic test, chest X-ray findings, treatment and its progression. RESULTS: 1) The age distribution was even and the ratio of male to female was 1:1. 2) The monthly distribution was most common in January(16.7%) and the seasonal distribution in autumn and winter(autumn: 30%, winter: 33.3%). 3) The cold agglutinin titers were higher than 1:64 in 12 cases(40%), and reached the peak level around 2 weeks from onset and antimycoplasma antibody titers were higher than 1:160 in 5 cases(16.7%). 4) On the chest X-ray, pulmonary infiltration was noted in 28 cases(93.3%) among 30 cases and right lower lobe involvement was the most common(33.3%) and both lower lobe involvement was noted in 7 cases(23.3%). 5) The mean treatment duration was most common(33.3%) in 1 week to 2 weeks after admission and 26 cases(86.7%) were improved within 4 weeks. 6) On admission, there was fever(> or =38.9degreesC) in 17 cases(56.7%), and the fever subsided in 12 cases(70%) within 3 days after treatment using erythromycin. CONCLUSION: The mycoplasmal pneumonia in adults shows milder clinical patterns than that in childhood and can be completely recovered without complication by early diagnosis and treatment.
Adult*
;
Age Distribution
;
Diagnosis
;
Early Diagnosis
;
Erythromycin
;
Female
;
Fever
;
Hospital Distribution Systems
;
Humans
;
Incidence
;
Male
;
Pneumonia*
;
Seasons
;
Serologic Tests
;
Sex Distribution
;
Sputum
;
Thorax
8.A Study of Progression to Cerebral Palsy in Premature Infants with Neurosonographic Abnormal Findings.
Kyeung Ho PARK ; Sang Hee KIM ; Hyung Won LEE ; Kil Hyun KIM ; Hak Soo LEE ; Ji Hye KIM ; Young Seok LEE
Journal of the Korean Pediatric Society 1997;40(9):1210-1218
PURPOSE: Although neonatal intensive care and development of obstetrics play a role in improving survival rate in prematurity, cerebral palsy (CP) is still one of the neurologic sequelae. We tried to find what kinds of risk factors in the patients with abnormal neurosonographic findings who developed CP later. This study was performed to predict early enough who will develop CP later and to treat rapidly for rehabilitation. METHODS: The one hundred and forty one infants with intraventricular hemorrhage, cyst, or abnormal increased periventricular echodensity in serial neurosonographic findings were admitted to the neonatal intensive care unit of Gil general hospital from January 1992 to December 1994. Neurosonographic findings in CP group and non-CP group during postpartum 18 months to 54 months were analysed retrospectively. RESULTS: 1) 18 of one hundred and forty one cases with abnormal neurosonographic findings developed CP. The duration of mechanical ventilation of the CP group was 11.6+/-16.1 days. It is significantly shorter than that of the control group (non-CP group : 2.2+/-7.0 day). The duration of oxygen therapy in the CP group was 22.4+/-19.2 days. Which is also significantly shorter than that of the control group (non-CP group : 5.4+/-8.4 day) (P<0.01). 2) Increased periventricular echodensity and the size of the cyst in neurosonographic findings in the CP group is significantly different from those of the non-CP group P<0.01). 3) In CP group (N=18), Increased periventricular echodensity and cyst formation were located most commonly in the parietal region. 4) The grade of the intraventricular hemorrhage in the CP group was significantly different from that in the non-CP group (P<0.01). 5) The neurosonographic findings give the diagnostic accuracy for predicting CP. CONCLUSIONS: We studied the relationship of the abnormal neurosonographic findings, CP, and associated risk factors. In review, By using neurosonographic examination the risk of the development of CP could be predicted, and by early diagnosis of CP the quality of the life of CP-patient could be better.
Cerebral Palsy*
;
Early Diagnosis
;
Hemorrhage
;
Hospitals, General
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature*
;
Intensive Care, Neonatal
;
Obstetrics
;
Oxygen
;
Postpartum Period
;
Rabeprazole
;
Rehabilitation
;
Respiration, Artificial
;
Retrospective Studies
;
Risk Factors
;
Survival Rate
9.The Usefulness of F-18-FDG PET and The Effect of Scan Protocol in Diagnosis of Intraocular Tumors.
Seong Woon HONG ; Chang Woon CHOI ; Sang Moo LIM ; Tae Won LEE ; Jae Sung LEE ; Weon Il YANG ; Byeung Il KIM ; Min Kyeung SIM
Korean Journal of Nuclear Medicine 1999;33(5):439-451
PURPOSE: It is important to differentiate malignant from benign lesions of intraocular masses in choosing therapeutic plan. Biopsy of intraocular tumor is not recommended due to the risk of visual damage. We evaluated the usefulness of F-18-FDG PET imaging in diagnosing intraocular neoplasms. MATERIALS AND METHODS: F-l8-FDG PET scan was performed in 13 patients (15 lesions) suspected to have malignant intraocular tumors. There were 3 benign lesions (retinal detachment, choroidal effusion and hemorrhage) and 10 patients with 12 malignant lesions (3 melanomas, 7 retinoblastomas and 2 metastatic cancers). Regional eye images (256*256 and 128*128 matrices) were obtained with or without attenuation correction. Whole body scan was also performed in eight patients (3 benign and 6 malignant lesions). RESULTS: All malignant lesions were visualized while all benign lesions were not visualized. The mean peak standardized uptake value (SUV) of malignant lesions was 2.64+/-0.57 g/ml. There was no correlations between peak SUV and tumor volume. Two large malignant lesions (>1000 mm3 ) showed hot uptake on whole body scan. But two medium-sized lesions (100-l000 mm3) looked faint and two small (<100 mm3) lesions were not visualized. The images reconstructed with 256*256 matrix showed lesions more clearly than those with 128X128 matrix. CONCLUSION: F-18-FDG PET scan is highly sensitivity in detecting malignant intraocular tumor. For the evaluation of small-sized intraocular lesions, whole body scan is not appropriate because of low sensitivity. A regional scan with sufficient acquisition time is recommended for that purpose. Image reconstruction in matrix size of 256*256 produced clearer images than the ones in 128X128, but it does not affect the diagnostic sensitivity.
Biopsy
;
Choroid
;
Diagnosis*
;
Humans
;
Image Processing, Computer-Assisted
;
Melanoma
;
Orbital Neoplasms
;
Positron-Emission Tomography
;
Retinoblastoma
;
Tumor Burden
;
Whole Body Imaging
10.External Carotid Artery Angioplasty and Stenting Followed by Superficial Temporal Artery to Middle Cerebral Artery Anastomosis.
Jun Kyeung KO ; Sang Weon LEE ; Tae Hong LEE ; Chang Hwa CHOI
Journal of Korean Neurosurgical Society 2009;46(5):488-491
A 31-year-old man presented with right hemiparesis, and magnetic resonance imaging revealed a small infarct at left basal ganglia. Digital subtraction angiography showed left cervical internal carotid artery (ICA) occlusion and severe stenosis of the ipsilateral external carotid artery (ECA) with collateral cerebral circulation fed by ECAs. Based on the results of a functional evaluation of cerebral blood flow, we performed preventive ECA angioplasty and stenting for advanced ECA stenosis to ensure sufficient blood flow to the superficial temporal artery. Eight weeks later, superficial temporal artery to middle cerebral artery (STA-MCA) anastomosis was performed. His postoperative course was uneventful and no additional transient ischemic attacks have occurred. To our knowledge, this is the first report of preventive angioplasty and stenting for advanced narrowing of an ECA before STA-MCA anastomosis for ipsilateral ICA occlusion.
Adult
;
Angiography, Digital Subtraction
;
Angioplasty
;
Basal Ganglia
;
Carotid Artery, External
;
Carotid Artery, Internal
;
Constriction, Pathologic
;
Dietary Sucrose
;
Humans
;
Ischemic Attack, Transient
;
Magnetic Resonance Imaging
;
Middle Cerebral Artery
;
Paresis
;
Stents
;
Temporal Arteries