Purpose: This study aimed to identify how job stress and teaching efficacy impacted organizational commitment. Methods: Data were collected from 158 nursing professors via an online survey, from Jan to June 2019. Results The study found that four factors affected the organizational commitment of nursing professors: i) type of nursing institution in which they are currently employed (β=-.16, p=.030), ii) position as an assistant professor (β=-.37, p=.012) and an associate professor (β=-.44, p=.002), iii) salary in the 50-59 million won range (β=.20, p=.024), and above 60 million won (β=.41, p<.001), and iv) professor’s teaching efficacy (β=-.18, p<.016). Conclusion: To increase the organizational commitment of four-year university professors, job characteristics should be considered. In the case of lower positions and salaries, additional compensation and programs that increase school affiliation should be introduced. Teaching methods training, lecture evaluation monitoring programs, and clinical training may also improve teaching efficacy.