In cases of severely atrophic edentulous maxilla, reconstruction, including lateral sinus floor elevation (LSFE) and alveolar ridge augmentation is performed using anorganic bovine bone matrix (ABBM) and/or autogenous bone. In this case, a 1:1 mixture of ABBM and octacalcium phosphate (OCP) was used for bilateral LSFE and vertical ridge augmentation. After a 7-month healing period, seven implants were successfully placed in the regenerated bone without the need for additional bone grafting. Core biopsy revealed a new bone formation rate of 43.8%. Among the residual graft materials, OCP and ABBM accounted for 2.9% and 7.1%, respectively and connective tissue comprised 46.2%. Within the limitations of this case, the combination of ABBM and OCP appeared to be a reliable choice for bone regeneration.

In cases of severely atrophic edentulous maxilla, reconstruction, including lateral sinus floor elevation (LSFE) and alveolar ridge augmentation is performed using anorganic bovine bone matrix (ABBM) and/or autogenous bone. In this case, a 1:1 mixture of ABBM and octacalcium phosphate (OCP) was used for bilateral LSFE and vertical ridge augmentation. After a 7-month healing period, seven implants were successfully placed in the regenerated bone without the need for additional bone grafting. Core biopsy revealed a new bone formation rate of 43.8%. Among the residual graft materials, OCP and ABBM accounted for 2.9% and 7.1%, respectively and connective tissue comprised 46.2%. Within the limitations of this case, the combination of ABBM and OCP appeared to be a reliable choice for bone regeneration.

In cases of severely atrophic edentulous maxilla, reconstruction, including lateral sinus floor elevation (LSFE) and alveolar ridge augmentation is performed using anorganic bovine bone matrix (ABBM) and/or autogenous bone. In this case, a 1:1 mixture of ABBM and octacalcium phosphate (OCP) was used for bilateral LSFE and vertical ridge augmentation. After a 7-month healing period, seven implants were successfully placed in the regenerated bone without the need for additional bone grafting. Core biopsy revealed a new bone formation rate of 43.8%. Among the residual graft materials, OCP and ABBM accounted for 2.9% and 7.1%, respectively and connective tissue comprised 46.2%. Within the limitations of this case, the combination of ABBM and OCP appeared to be a reliable choice for bone regeneration.

No abstract available.
Humans* ; Interleukin-12* ; Mycobacterium tuberculosis* ; Mycobacterium* ; Tuberculosis, Pulmonary* ; Tumor Necrosis Factor-alpha*

No abstract available.
Humans ; Listeria* ; Meningitis, Listeria*

No Abstract Available.
Humans ; Interleukin-12* ; Interleukin-18* ; Tuberculosis, Pleural*

Mycobacterium tuberculosis infected macrophages can become ineffective at activating CD4+ T cells through presentation of peptide antigens by MHC class II, possibly contributing to the ability of M tuberculosis to persist despite the presence of an intact immune system. Presentation of lipid antigens may help to overcome this problem. CD1 represents the key component of an MHC independent pathway for presentation nonpeptide lipid antigens to T cells. The 38 kDa glycolipoprotein antigen of M. tuberculosis is actively secreted. The antigen induces strong antibody and T-cell responses and provided partial protection against M. tuberculosis infection in mice when it is administered either entrapped in biodegradable microparticles or in the form of a DNA vaccine. But an selective anergy to stimulation with peptide of the 38 kDa was observed in the majority of tuberculosis patients. An 38 kDa antigen has been isolated by affinity chromatography using a monoclonal antibody. This antigen contains some immunosuppressive cell wall associated antigens such as lipoarabinomannan. Therefore, we purified the 38 kDa glycolipoprotein from the culture filtrate of M tuberculosis H37Rv by ammonium sulfate precipitation (55~80%), hydroxylapatite and DEAE-Sephacel column. The purified antigen showed three major bands on isoelectric focusing gel, and two-dimensional electrophoresis (2-DE) analysis of this antigen revealed five distinct spots of the 38 kDa molecular mass. One of five spots had a N-terminal sequence identical to that of the 38 kDa glycolipoprotein (pstS-1). Other protein spots could not determine sequences. An antiserum against the recombinant 38 kDa antigen of M tuberculosis reacted strongly with the purified the 38 kDa antigen.
Ammonium Sulfate ; Animals ; Cell Wall ; Chromatography, Affinity ; DNA ; Durapatite ; Electrophoresis ; Humans ; Immune System ; Isoelectric Focusing ; Macrophages ; Mice ; Mycobacterium tuberculosis* ; Mycobacterium* ; T-Lymphocytes ; Tuberculosis

In order to observe the changes in left ventricular function during coronary artery occlusion and reperfusion, left anterior descending (LAD) coronary arteries in the anesthetized dogs were occluded for 1 hour and then reperfused for 4 hours. Hemodynamic indexes of global systolic and diastolic function and regional wall thickness changes as a regional contractile index were measured during occlusion and reperfusion. The results were as follows; 1) Indexes of global systolic function (left ventricular peak systolic pressure, peak positive dP/dt) and global diastolic function (peak negative dP/dt, time constant, left ventricular end-diastolic pressure) showed deterioration in early occlusion period (10-30 minutes) but gradually improved even if coronary occlusion persisted. Reperfusion did not induce significant changes except that peak positive dP/dt transiently deteriorated 30 minutes after reperfusion and left ventricular end-diastolic pressure decreased 1.5-2 hours after reperfusion. 2) Indexed of regional function (i.e, end-diastolic thickness and % systolic thickening of anterior left ventricular wall) deteriorated by 10 minutes' occlusion which persisted during the entire occlusion period. Reperfusion induced no significant improvement in regional contractile function compared with occlusion 60 minutes' data, which suggested reperfusion for 4 hours after 1 hour's LAD occlusion may be insufficient for the ischemic region to recover its contractility. 3) Reperfusion arrhythmia (ventricular tachycardia) was noted in most (6/9) of the dogs, one of which deteriorated into ventricular fibrillation and the others spontaneously converted to normal sinus rhythm.
Animals ; Arrhythmias, Cardiac ; Blood Pressure ; Coronary Occlusion ; Coronary Vessels* ; Dogs ; Hemodynamics ; Reperfusion* ; Ventricular Fibrillation ; Ventricular Function, Left*

Infected urachal cyst is a rare disorder. While a urachal cyst is usually asymptomatic, the infected cyst may mimic a variety of acute intraabdominal infection. We have experienced a case of infected urachal cyst in a 3 year old boy complaining of high fever and diarrhea. During hospitalization, symptoms and sings of acute peritonitis dominated the clinical feature. Abdominal sonogram, abdominal computerized tomography and cavitogram demonstrated cystic mass posterior to central abdominal wall. Pus was drained from the cystic lesion by ultrasound-guided needle aspiration and indwelling catheter insertion. E.coli was cultured from pus. In the differential diagnosis of acute abdomen ultrasonographic examination of abdomen should be recruited to rule out the infected urachal cyst.
Abdomen ; Abdomen, Acute ; Abdominal Wall ; Catheters, Indwelling ; Child, Preschool ; Diagnosis, Differential ; Diarrhea ; Fever ; Hospitalization ; Humans ; Intraabdominal Infections ; Male ; Needles ; Peritonitis* ; Suppuration ; Urachal Cyst*

Major known causes of neonatal adrenal insufficiency are prolonged maternalsteroid use, adrenal hemorrhage from the perinatal stress and adrenogenital syndrome. Theoretically adrenal aplasia might be a cause of neonatal adrenal insufficiency but it has not been reported yet. We had experienced a case of adrenal aplasia in a 5 day-old male neonate whose chief complaint was hyperpigmentation. His laboratory findings were compatible with adrenal insufficiency and adrenal gland was not detected by the ultrasonography and thin section abdominal CT. We reported a case of adrenal aplasia with a brief review of the related literature.
Adrenal Glands ; Adrenal Insufficiency ; Adrenogenital Syndrome ; Hemorrhage ; Humans ; Hyperpigmentation ; Infant, Newborn ; Male ; Tomography, X-Ray Computed ; Ultrasonography