Prenatal chromosome analysis of amniotic cells at 18 weeks of gestation showed a male fetus to carry a large 15p+ derivative chromosome inherited from his mother. Extra genetic material on the short arm of chromosome IS was silver-negative with Ag-NOR (nucleolus organizer regions) stain, but stained darkly with C-banding method like the distal heterochromatic segment of the Y long arm. Fluorescence in situ hybridization (FISH) using two DNA probes (DYZ1 and D15Zl) showed a red fluorescent signal on 15p+ In addition to a green chromosome 15 centromere signal, confirming 15p to be from the distal Yq heterochromatin.
Arm ; Centromere ; Chromosomes, Human, Pair 15 ; DNA Probes ; Fetus ; Fluorescence ; Heterochromatin ; Humans ; In Situ Hybridization ; Male ; Mothers ; Pregnancy

Tracheal gaenesis is an extremely rare congenital anomaly and is characterized by totally or partially undeveloped trachea. In many instances, the lesion has been associated with malformations in other organ systems. This anomaly is classified into 3 types based on developmental period of the respiratory tract. We report a case of tracheal agenesis with tracheoesophageal fistula in a 2-hour-old male. Postmortem examination revealed that the upper and mid portion of the trachea was absent but 1 cm segment of the trachea above the carina was present. The proximal end to this trachea opened to the esophagus by a fistula, 1 cm in diameter. The well-formed larynx ended blindly in a fibrous sac at which thyroids and cartilage islands are noted. Associated anomalies were bilobed right lung and single umbilical artery.

PURPOSE: The purpose of this study was to determine the effects of foot reflexology on fatigue and insomnia in patients suffering from coal workers' pneumoconiosis. METHOD: This study was a quasi-experimental study of pre-test and post-test design in a non-equivalent control group. The subjects of this study consisted of both the experimental group of twenty-nine and the control group of thirty coal workers' pneumoconiosis patients. Data was collected from December 10, 2002 to February 15, 2003. Foot reflexology was performed for 60 minutes twice a week through five weeks in the experimental group, but none in the control group. To evaluate the effects of foot reflexology, the scores of fatigue and insomnia were measured before and after the experiment in both groups. Fatigue was evaluated by Fatigue Symptoms Inventory. Insomnia was measured with the visual analogue scale (VAS). Data of this experiment was analyzed by Chi-square test, t-test, unpaired t-test and Repeated Measures ANOVA with the SAS Program. RESULTS: The scores of fatigue and insomnia decreased in the experimental group but not in the control group. There was a significant difference of fatigue and insomnia between the two groups. CONCLUSION: It is suggested that foot reflexology might have beneficial effects on reducing fatigue and insomnia in patients suffering from coal workers' pneumoconiosis, and can be recommended as a nursing intervention program for patients with coal workers' pneumoconiosis.
Sleep Initiation and Maintenance Disorders/complications/*nursing ; Pneumoconiosis/*complications/physiopathology ; Middle Aged ; *Massage ; Male ; Humans ; *Foot ; Fatigue/complications/*nursing ; *Coal Mining ; Aged

No abstract available.
Acinar Cells* ; Biopsy, Fine-Needle* ; Carcinoma, Acinar Cell* ; Parotid Gland*

Congenital megacalyces is a congenital renal disease characterized by hypoplasia of the medulla and a non-obstructive dilatation of the calyces. More than 100 cases have been reported in the literature after first described by Puigvert in 1963, but it has been reported only three cases (two cases of adults and one case of child) in the literatures in Korea. The etiology of the congenital megacalyces is unknown. Renal pelvis and ureter are mostly normal in size and there is no urinary obstruction or reflux. Renal medulla of congenital megacalyces is thinner than that of normal kidney but renal cortex retains its normal thickness and function. This is features that help to distinguish megacalyces from obstructive atropy. The calyces are polygonal in shape and the majority of kidney with megacalyces have increased number of calyces. Since congenital megacalyces is a non-progressive lesion, it is important to recognize the clinical entity and avoid unnecessary surgery. We report one case of congenital megacalyces without urinary obstruction or reflux with a brief review of related literatures.
Adult ; Dilatation ; Humans ; Kidney ; Kidney Pelvis ; Korea ; Unnecessary Procedures ; Ureter

Lipoblastoma is a variant of lipoma and lipomatosis occuring almost exclusively during the years of infancy and early childhood. These lesions differ from lipoma and lipomatosis by their cellular immaturity and their close resemblance to the myxoid form of liposarcoma. We experienced one case of lipoblastoma in 21 months old boy who suffered from respiratory tract symptoms such as cough, sputum production, and mild fever. At first he was misdiagnosed pneumonia and treated with antibiotics and conservative management for pneumonia. Later he was rediagnosed as tumor in the left upper lung. For removal of tumor he had operative excision and the biopsies were showed compatible to lipoblastoma. A brief review of related literatures is also presented.
Anti-Bacterial Agents ; Biopsy ; Cough ; Fever ; Humans ; Infant ; Lipoblastoma* ; Lipoma ; Lipomatosis ; Liposarcoma ; Lung ; Male ; Pneumonia ; Respiratory System ; Sputum

Somatostatinoma is rare endocrine tumor that was first described in 1977 by Ganda et al. and Larsson et al. simultaneously. It seems nonfunctioning at clinical level. But it may present with diabetes, diarrhea, cholelithiasis, steatorrhea, indigestion, hypochlorhydria, and anemia. In contrast with pancreatic somatostatinoma, duodenal somatostatinoma, in general, is clinically silent. Duodenal endocrine tumors show similar histologic pattern. Therefore, the definite diagnosis is performed by immunohistochemistry and electron microscopic examination. We have experienced a case of somatostatinoma of duodenum in a 62-year-old male. He has complained generalized pruritus for one year and jaundice for 2 weeks. Grossly, the mass was a intraluminary protruding, polypoid lesion with focal mucosal erosion at immediately distal to Ampulla of Vater. Histologically, it showed tall, cylindrical cells with distinct cell membranes, having granular cytoplasm and small innocent looking nuclei. No mitosis was seen. The tumor cells were arraged in small solid groups and trabeculae, separated by fibrovascular stroma. Immunohistochemically, the tumor cells were strongly positive with somatostatin and negative with several other hormonal and neuroendocrine markers. Ultrastructurally, the cytoplasm contains numerous, homogeneous low electron dense secretory granules, which are essentially similar to those seen in normal delta cells.

No abstract available.
Hyperprolactinemia*

PURPOSE: This study was done to examine the sleep pattern of ICU patients, as well as characteristics of, and factors related to sleep disturbances, and state anxiety. It was done to provide the basic data for effective nursing interventions to improve quality of sleep for these patients. METHODS: The participants were 104 patients who were admitted to the surgical ICU in a hospital in Seoul. To measure sleep patterns, the Verran and Snyder-Halpern Sleep Scale and the Sleeping Scale developed by Oh et al.(1998) were used. Characteristics of sleep disturbances were measured using the Sleep characteristics scale developed by Park(1999). To measure factors related to sleep disturbances, thirty items developed by Oh(1998) were used. RESULTS: There was no statistically significant difference in the sleep patterns according to the general characteristics of the patients. The characteristics of sleep disturbances showed statistically significant differences in general and specific characteristics of sleep patterns but there was no statistically significant difference according to the general characteristics of the patients. There were significant negative correlations between factors related to sleep disturbances and general and specific characteristics of sleep patterns but there were no statistically significant difference according to the general characteristics of the patients. CONCLUSION: The results showed that the majority of patients staying in the surgical ICU experienced sleep disturbances and that the physical factor was the major factor of sleep disturbances.
Anxiety ; Humans ; Intensive Care Units ; Nursing ; Seoul

No abstract available.
Leukodystrophy, Metachromatic*