1.The Recovery of Epidermal Barrier after Stratum Corneum Injury and the Changes of Epidermal Lipid Contents in Hand Eczema and Normal Subjects.
Seung Hun LEE ; Kyeong Han YOON ; Mi Sun WHANG
Korean Journal of Dermatology 1995;33(6):1053-1059
BACKGROUND: In eczematous skin it is expected that altered defense mechanisms are employed against an injury, which mechanisms include alterations in the stratum corneum barrier function and lipid contents. OBJECTIVE: To investigaten aspect of pathophysiology of hand eczema by comparing the water holding capacities and transepidermal water loss(TEWL) after injuries on the skin and by comparing the epidermal lipid contents between hand eczema and normal subjects. METHODS: The water holding capacities were checked by corneometer, and the TEWL were checked after epidermal barrie! destruction with acetone or adhesive tapes. The epidermal lipids were extracted with acetone, ther (1: 1 v/v) mixture solvent and analysed by HP- TLC. RESULTS: The water holdingapacities were decreased in eczema of the palm, but the recoveries of TEWL and the lipid content did not differ between hand eczema and normal subjects. CONCLUSION: The water holding capacities were decreased in the eczematous skin. But there were no significant differencies in the recovery of destructed epidermal barrier and the epidermal lipid contents.
Acetone
;
Adhesives
;
Defense Mechanisms
;
Eczema*
;
Hand*
;
Skin
;
Water
2.Craniofacial resection for a case of chondrosarcoma in nasal cavity.
Jang Su SUH ; Moon Kyeong DO ; Kyeong Hang LEE ; Kwon Yeoung HUN
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):822-826
No abstract available.
Chondrosarcoma*
;
Nasal Cavity*
3.Massive transfusion in Severance hospital.
Mi Kyeong LEE ; Hyun Ok KIM ; Seong Geun HONG ; Oh Hun KWON ; Jin Ju KIM
Korean Journal of Blood Transfusion 1993;4(1):23-28
No abstract available.
4.A case of alopecia universalis without the involvement of scalp hairs.
Kyeong Han YOON ; Seung Hun LEE ; Sung Ku AHN ; Won Soo LEE
Yonsei Medical Journal 1995;36(1):97-101
A case of alopecia universalis in a 45-year-old male was reported. The hair loss initiated on the eyebrows and progressed to the whole body, but the scalp hairs were well preserved. Histopathologic features of eyebrows were compatible findings with alopecia areata. This is a unique case of alopecia universalis without any involvement of scalp hairs.
Alopecia/*pathology
;
Case Report
;
Extremities
;
Eyebrows/pathology
;
Genitalia, Male
;
Hair/*pathology
;
Human
;
Male
;
Middle Age
;
Scalp/*pathology
;
Skin/pathology
5.Comparison of Health Behavior Change Before and After the Percutaneous Coronary Intervention among Coronary Artery Disease Patients.
Jung Hun LEE ; Kyeong Soo LEE ; Tae Yoon HWANG
Journal of Agricultural Medicine & Community Health 2016;41(3):140-151
OBJECTIVES: The purpose of this study was to investigate health behaviors of patients before and after percutaneous coronary intervention (PCI). METHODS: The subjects of this study were 120 men and women whose age ranged from 40 years to 69 years among the patients who received percutaneous coronary intervention in Y university hospital that was located in Daegu city and who had diagnosed for 3 months or more and less than 2 years. Structured questionnaire was used to conduct self-administered survey from May 15 to October 12 in 2012. RESULTS: Patients's health behavior score was ranged from 46 to 94 points after the PCI intervention. The score was 65.42±12.99 points before and significantly increased up to 72.53±10.18 points after the PCI intervention (p<.001). According to subcategory of health behavior, significant differences were found in scores of health responsibility (increased interest in health, watching of lecture on health and behavior to be punctual on counseling or medical treatment), diet, smoking, and drinking (p<.001, p=.039, p=<.001). However, no significant change was found in practice efforts such as exercise, eating habits and relaxation for stress management. CONCLUSIONS: In conclusion, it is necessary to provide education and counseling that enabling patients to improve smoking, drinking, practicing exercise and healthy eating habits.
Coronary Artery Disease*
;
Coronary Vessels*
;
Counseling
;
Daegu
;
Diet
;
Drinking
;
Eating
;
Education
;
Female
;
Health Behavior*
;
Humans
;
Male
;
Percutaneous Coronary Intervention*
;
Relaxation
;
Smoke
;
Smoking
6.The Regulation of TRAF Expression by TNF-alpha in Rheumatoid Synoviocytes.
Ji Hee PARK ; Young Sik SHIM ; Doo Hun SUN ; Chul Soo CHO ; Ho Youn KIM ; Suk Kyeong LEE
Korean Journal of Immunology 2000;22(3):139-148
No abstract available.
Tumor Necrosis Factor-alpha*
7.Population pharmacokinetics and bayesian feedback method for nortriptyline dosage optimisation.
Sang Goo SHIN ; Jong Inn WOO ; In Jin JANG ; Chan Woong PARK ; Jae Jin KIM ; Jin Pyo HONG ; Kyeong Hun LEE
Journal of Korean Neuropsychiatric Association 1992;31(5):884-894
No abstract available.
Nortriptyline*
;
Pharmacokinetics*
8.Cardiac tamponade with chylopericardium in a 6-year-old boy with central venous catheter: a case report
In Kyung LEE ; Ji Weon LEE ; Kyeong Hun LEE ; Jin Hee KIM ; Bongjin LEE ; June Dong PARK
Pediatric Emergency Medicine Journal 2024;11(2):75-81
Cardiac tamponade (CT) is a rare but potentially lethal complication associated with central venous catheters (CVCs). We present a 6-year-old boy who developed CT after CVC insertion in the right internal jugular vein, with its tip in the inferior vena cava. Initially, he was hospitalized to a tertiary hospital with presumptive diagnoses of pneumonia and left ankle cellulitis. Three days after CVC placement, he developed CT, manifesting as recurrent episodes of hypotension and bradycardia. Once a bedside echocardiography showed CT, pericardiocentesis was performed, resulting in successful resuscitation. Pericardiocentesis revealed a milk-appearing pericardial fluid, indicating chylopericardium. The boy also underwent debridement and joint irrigation of the left ankle, which turned out to be osteomyelitis. Although CVC tips in most reported CVC-related CTs have been commonly located in the right atrium, our case featured a tip located in the inferior vena cava. Additionally, chylopericardium was likely due to the extravasation of total parenteral nutrition fluid, rather than the usual causes, such as recent thoracic surgery. Understanding the mechanisms behind chylopericardium associated with CVCs and timely pericardiocentesis is crucial for improving the outcomes.
9.A Randomized Prospective Trial Comparing Oral Sodium Phosphate with Magnesium citrate in Preparing of Patients for Double Contrast Barium Enema.
Eun Joo LEE ; Sung Woo LEE ; Hyeon Kyeong LEE ; Chang Hun YANG ; Soon KIM ; Yoen Hee OH ; Seung Hyeon KIM
Journal of the Korean Radiological Society 2004;50(6):427-431
PURPOSE: The purpose of this study was to compare two bowel preparation agents, sodium phosphate solution with magnesium citrate solution. MATERIALS AND METHODS: A total of 94 subjects that underwent a double-contrast barium enema were included in this study. Bowel preparation before performing the barium study was done by using a sodium phosphate solution in 47 subjects and by using a magnesium citrate solution in the other 47subjects. We evaluated the presence or absence of side effects when using these bowel preparation agents. Two radiologist who were blinded to the type of bowel preparation evaluated the quality of bowel preparation at the colonic segments (ascending, descending, and sigmoid colon) on the radiographs obtained by double-contrast barium enema, with regard to stool cleansing, water retention, barium coating and bubble formation. RESULTS: The side effects, such as abdominal clamping pain, nausea, hunger pain and chill occurred more frequently in the sodium phosphate group than in the magnesium citrate group (p<0.001). Stool retention was more frequently found in the magnesium citrate group (p<0.001). However, no statistical difference was noted on the status of water retention and barium coating between two groups. Gas bubble formation was more commonly seen in the sodium phosphate group (p<0.001). The sodium phosphate solution appeared to be more effective in cleansing the right colon (p=0.001). CONCLUSION: Sodium phosphate solution appears to be more effective for colonic cleansing, with a lower incidence of side effects, than when using magnesium citrate solution.
Barium*
;
Citric Acid*
;
Colon
;
Colon, Sigmoid
;
Constriction
;
Enema*
;
Humans
;
Hunger
;
Incidence
;
Magnesium*
;
Nausea
;
Prospective Studies*
;
Sodium*
;
Water
10.Hypoxic Damage in the Contralateral Testis after Unilateral Testicular Torsion in a Rat Model: Hemodynamic Change and Expressions of Hypoxia Inducible Factor-1alpha, VEGF and Apoptosis in the Contralateral Testis.
Kyeong Mi LEE ; Sang Don LEE ; Chang Hun LEE ; Byung Oh KIM
Korean Journal of Urology 2005;46(4):399-405
PURPOSE: The present study aimed to evaluate the hypoxic damage in the contralateral testis after unilateral testicular torsion in a rat model, using hemodynamic change, the expression of hypoxia inducible factor-1alpha(HIF-1alpha) and apoptosis. MATERIALS AND METHODS: Thirty-five male albino Sprague-Dawley rats were randomly divided into 7 groups: 0 and 6 hours after sham operations, 6, 12 and 24 hours, and 3 and 7 days after the unilateral testicular torsion. Torsion was created by rotating the left testis 720 degrees, in a clockwise direction, which was maintained by fixing the testis to the scrotum with a silk suture. The testicular blood flow of the contralateral testis was measured by laser flowmetry, both before and after the testicular torsion. After bilateral orchiectomies had been performed in each group, the expressions of HIF-1alpha and vascular endothelial growth factor (VEGF), as well as apoptosis were determined by immunohistochemical staining and Western blot analysis. RESULTS: The blood flow of the contralateral testis after the unilateral testicular torsion significantly decreased compared with that of the sham group (p<0.05). In the immunohistochemical staining, the expression of HIF-1alpha protein increased in the testicular torsion group compared to that of the sham group, and was markedly apparent 12 hours after the testicular torsion. The apoptotic cell index was also significantly higher in the testicular torsion group than in the sham group (p<0.05). In the Western blot study, the HIF-1alpha and VEGF expressions were increased in the testicular torsion group compared to those in the sham group 6 hours after the testicular torsion. CONCLUSIONS: This study suggests that the decreased testicular blood flow of the contralateral testis during ipsilateral testicular torsion induces HIF-1alpha, resulting in apoptosis of germ cells.
Animals
;
Anoxia*
;
Apoptosis*
;
Blotting, Western
;
Germ Cells
;
Hemodynamics*
;
Humans
;
Male
;
Models, Animal*
;
Orchiectomy
;
Rats*
;
Rats, Sprague-Dawley
;
Regional Blood Flow
;
Rheology
;
Scrotum
;
Silk
;
Spermatic Cord Torsion*
;
Sutures
;
Testis*
;
Vascular Endothelial Growth Factor A*