1.Obstructive pneumonitis of right lower lung field.
Kang Hyun AHN ; Chong In LEE ; Yong Gyu LEE ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 1992;39(4):366-369
No abstract available.
Lung*
;
Pneumonia*
2.ECG Sign of Cor Pulmonale in Coal Workers' Pneumoconiosis Died from Cardio-respiratory faiture.
Yong Hee CHEON ; Kye Chul SHIN
Korean Journal of Occupational and Environmental Medicine 1990;2(1):71-74
Electrocardiographic sign was studied for the evaluation of the state of Corpulmonale in coal workers' pneumoconiosis who were admitted and dead as complication of CWP in Don-ghae hospital, Fourty-eight cases were gatherpd. The prevalence rate of right axis deviation was 28.3%. p-pulmonale in lead II was 30.4%, R/S< or =1 in V5 was 23.9. But che pulmonary artereal pressure can be increased without the change of ECG. so the elortrocardiugraphical sign should be treated as reference data.
Axis
;
Coal*
;
Electrocardiography*
;
Pneumoconiosis*
;
Prevalence
;
Pulmonary Heart Disease*
3.The significance of gallium scan in miliary tuberculosis.
Hyung In KIM ; Choon Jo JIN ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 1993;40(5):558-564
No abstract available.
Gallium*
;
Tuberculosis, Miliary*
4.Evaluation of four serologic methods for the diagnosis of leptospirosis.
Kap Jun YOON ; Wonkeun SONG ; Chang Hoon LEE ; Inryul CHOI ; Kye Chul SHIN ; Hee Bok OH
Korean Journal of Clinical Pathology 1992;12(2):265-270
No abstract available.
Diagnosis*
;
Leptospirosis*
5.Evaluation of four serologic methods for the diagnosis of leptospirosis.
Kap Jun YOON ; Wonkeun SONG ; Chang Hoon LEE ; Inryul CHOI ; Kye Chul SHIN ; Hee Bok OH
Korean Journal of Clinical Pathology 1992;12(2):265-270
No abstract available.
Diagnosis*
;
Leptospirosis*
6.Closure of bronchoesophageal fistula with tissue adhesive tisseel: 2 cases report.
Doo Yun LEE ; Chi Soon YOON ; Eun Ki KIM ; Kye Chul SHIN
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(5):470-474
No abstract available.
Fibrin Tissue Adhesive*
;
Fistula*
;
Tissue Adhesives*
7.Relationship Between Tumor Angiogenesis, sgtage and Prognosis in Non-Small Cell Lung Cancer.
Won Yeon LEE ; Chong Ju KIM ; Pyo Jin SHIN ; Mee Yon CHO ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 2001;50(5):557-567
BACKGROUND: Tumor angiogenesis is required for tumor growth and metastasis. In this study, we investigated the correlation between the intensity of angiogenesis and stage, nodal status, histologic type, metastasis and survival rate of non-small cell lung cancer. METHOD: Formalin fixed, paraffin embedded surgical specimens of 45 patients who had surgically resected primary non-small cell lung cancers without pre or post perative adjuvant chemotherapy or radiotherapy were examined. The microvessel count(MVC) was demonstrated by immunohistochemical staining for CD31(platelet ednothlial cell adhesion molecule, PECAM). RESULTS: Microvessel counts(MVCs)in stage IIIA and IIIB were higher than in stage I and II(p<0.05). The MVC in patients with lymph node metastasis was higher than that in patients without lymph node metastasis, although the difference was not statistically significant(p>0.05). However, in adenocarcinoma, the MVC in patients with lymph node metastasis was significantly higher than that seen in patients without lymph node metastasis(p<0.05). The MVC in adenocaricinoma was higher than that in squamous cell carcinoma(p<0.05). The difference between the MVCs of adenocarcinoma and squamous cell carcinoma was not statistically significant in stage Iand II or NO stage(p>0.05). However, in stage IIIA and IIIB or N1~3 stage, the MVC in adenocarcinoma was higher than that in squamous cell carcinoma(p<0.05). MVC was more increased when metastasis developed within 12 months. In the same histologic type and stage, the duration of survival time in patients with high MVC was shorter than in patients with low MVC, however the difference was not statistically significant(p>0.05). The survival rate in patients with high MVCs was lower than that in patients with low MVCs(P<0.05). CONCLUSION: In non-small cell lung cancer, MVC correlated relatively well with pathologic stage, nodal status (limited in patients with adenocarcinoma), histologic type, postoperative metastasis and survival rate. However, in the same histologic type and stage, MVC was not significantly related to the duration of survival. Therefore the assessment of the intensity of angiogenesis in non-small cell lung cancer may be helpful in predicting prognosis and in selecting patients for systemic adjuvant therapy of potential metastasis according to the results.
Adenocarcinoma
;
Carcinoma, Non-Small-Cell Lung*
;
Carcinoma, Squamous Cell
;
Cell Adhesion
;
Chemotherapy, Adjuvant
;
Formaldehyde
;
Humans
;
Lung Neoplasms
;
Lymph Nodes
;
Microvessels
;
Neoplasm Metastasis
;
Paraffin
;
Prognosis*
;
Radiotherapy
;
Survival Rate
8.Clinical Significance of Plasma TGF-β1 in Coal Workers' Pneumoconiosis.
Chong Ju KIM ; Won Yeon LEE ; Ae Ra HONG ; Pyo Jin SHIN ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 2001;50(1):76-83
BACKGROUND: Coal workers' pneumoconiosis is a fibrotic lung disease resulting from chronic inhalation of coal dust. The precise mechanism of lung fibrosis in coal workers' pneumoconiosis is uncertain. However, a relationship between the stimulation of fibroblast proliferation and collagen production by mediators released from inflammatory and resident lung cells is thought to be a major factor. The transforming growth factor-β(TGF-β), a multifunctional cytokine and growth factor, plays a key role in the scarring and fibrotic processes due to its ability to induce extracellular matrix proteins and modulate the growth and immune function of many cell types. To determine the involvement of TGF-βin the development of lung fibrosis in coal workers' pneumoconiosis, the TGF-β1 level in plasma was measured in patients with coal workers' pneumoconiosis. METHODS: Plasma was collected from 40 patients with coal workers' pneumoconiosis (20 with simple coal workers' pneumoconiosis and 20 with complicated coal workers' pneumoconiosis) and from 10 normal controls. The ELISA method was used to measure the plasma TGF-β1 concentration. RESULTS: Compared to the control group (0.63±0.18 ng/mL), there was no significant difference in the plasma TGF-β1 level in patients with simple coal workers' pneumoconiosis (0.64±0.17 ng/mL) (p>.05). However, in patients with complicated coal workers' pneumoconiosis the plasma TGF-β1 level (0.79±0.18 ng/mL) was significantly higher than in patients with simple coal workers' pneumoconiosis and control group (p<0.05). CONCLUSION: The data suggests that TGF-β1 has some influence in the development of lung fibrosis in coal workers' pneumoconiosis.
Cicatrix
;
Coal*
;
Collagen
;
Dust
;
Enzyme-Linked Immunosorbent Assay
;
Extracellular Matrix Proteins
;
Fibroblasts
;
Fibrosis
;
Humans
;
Inhalation
;
Lung
;
Lung Diseases
;
Plasma*
;
Pneumoconiosis*
;
Pulmonary Fibrosis
9.Time series analysis on outcomes of tuberculosis control and prevention program between small areas in Korea : with patient.
Chun Bae KIM ; Heon CHOE ; Kye Chul SHIN ; Jong Ku PARK ; Soo Keun HAM ; Eun Mi KIM
Tuberculosis and Respiratory Diseases 2000;48(6):837-852
BACKGROUNDS: Today, tuberculosis cannot only be cured medically, but also controlled by public health. Despite the overall worldwide decline in tuberculosis, the disease continues to be a significant problem among developing countries and in the slums of large cities in some industrialized countries. Particularly, this communicable disease has come into the public health spotlight because of its resurgence in the 1990's Our country has been operating the Korean National Tuberculosis Control Program since 1962, focusing around public health centers. Therefore, this study aims to compare the effectiveness of tuberculosis control activities, one of the major public health activities in Korea, by producing indexes, such as the yearly registration rate per 100,000 population and treatment compliance of tuberculosis on in small areas (communities). METHODS: This work was accomplished by constructing a time-series analytic model using data from "1980~2000 : the Yearly Statistical Report" with patient registry data of 234 City. County. District public health centers and by identifying the factors influencing the tuberculosis indexes. RESULTS: The trends of pulmonary tuberculosis positive point prevalence and pulmonary tuberculosis negative point prevalence on X-ray screening have declined steadily, beginning in 1981 and continuing to 1998 by region (city. county. district). Although the tuberculosis mortality rate steadily shows a declining trend by year and region, but Korea still ranks first among 29 OECD countries in 1998, with a tuberculosis mortality rate of 7.1 per 100,000 persons, according to the time-series analysis for fatal diseases. CONCLUSION: The results of the study will form the fundamental basis of future health care planning and the Korean Tuberculosis Surveillance System on 2000. Since the implementation of local autonomy through the Local Health Act of 1995. it has now become vital for each city. county. district public health centers to determine its own priorities for relevant health care management, including budget allocation and program goals.
Budgets
;
Communicable Diseases
;
Compliance
;
Delivery of Health Care
;
Developed Countries
;
Developing Countries
;
Humans
;
Korea*
;
Mass Screening
;
Mortality
;
Poverty Areas
;
Prevalence
;
Public Health
;
Tuberculosis*
;
Tuberculosis, Pulmonary
10.A case of bullous lung disease disappeared spontaneously.
Chong Ju KIM ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 1996;43(3):455-460
In general, a bulla of the lung is large, air contained sac and it is more than 1cm in diameter, and its wall is well defined and less than 2mm thick. The natural course of bulla of the lung is said to follow a pattern of progressive deterioration. It is a progressive disease, and spontaneous resolution of bulla is very unusual. In the world only two cases of spontaneous resolution of bulla have been reported. We experienced a case of bullous lung disease complicated from miliary tuberculosis in which the bulla was disappeared spontaneously following bulla infection.
Lung Diseases*
;
Lung*
;
Tuberculosis, Miliary