A case of osteomalacia is presented. A 46-year-old woman had had complaints of pain in low back and both knee joints for four years. A bell shaped thorax with kyphoscoliosis was noted. She was diagnosed as an osteomalacia by roentgenograph and laboratory examinations. Treatment by medication was followed with good results.
Female ; Humans ; Knee Joint ; Middle Aged ; Osteomalacia ; Thorax

No abstract available.
Humans*

No abstract available.
Humans ; Hyperbilirubinemia, Hereditary* ; Siblings*

BACKGROUND: The aim of this study was to compare the efficacy of ketorolac, paracetamol, and paracetamol plus morphine on pain relief after thyroidectomy. METHODS: Eighty patients were randomly allocated to one of the 4 groups: normal saline (group C), ketorolac 30 mg (group K), paracetamol 1 g (group P), and paracetamol 700 mg plus morphine 3 mg (group PM). Each regimen was administered intravenously (IV) 30 min. before the end of surgery. If pain was not relieved, patients received an IV bolus of pethidine hydrochloride 25 mg. Pain intensity using a visual analogue scale (VAS) was recorded at 0.5, 1, 2, 4, and 6 hr after the end of surgery. RESULTS: VAS at 0.5 and 1 hr after the end of surgery were significantly lower in group K, group P, and group PM than in group C (P < 0.05). The number of patients receiving pethidine hydrochloride at 0.5 and 1 hr after the end of surgery was significantly lower in group K, group P, and group PM than in group C (P < 0.05). There was no significant difference among the groups in the incidences of adverse events associated with study medications and patient satisfaction (P > 0.05). CONCLUSIONS: Paracetamol 1 g IV possesses a similar analgesic efficacy to ketorolac 30 mg IV after thyroidectomy. Paracetamol may represent an alternative to ketorolac for pain prevention after mildly to moderately painful surgery in situations where the use of NSAIDs is unsuitable.
Acetaminophen ; Analgesics ; Anti-Inflammatory Agents, Non-Steroidal ; Humans ; Incidence ; Ketorolac ; Meperidine ; Morphine ; Patient Satisfaction ; Thyroidectomy

No abstract available.
Animals ; Cloning, Molecular* ; Interleukin-2* ; Mice*

PURPOSE: To assess the value of gray-scale stimulated acoustic emission in differential diagnosis between hepatocellular carcinoma and metastatic adenocarcinoma. MATERIALS AND METHODS: Twenty-four cases of epatocellular carcinoma (HCC) in 23 patients and 26 cases of metastatic adenocarcinoma in 14 patients were prospectively examined using the pulse-inversion harmonic technique after intravenous SH U 508A administration. Gray-scale stimulated acoustic emission (SAE) was measured 5 mins after bolus injection of a contrast agent (4g, 400 mg/ml). The presence or absence of SAE signals at internal and marginal areas of the tumor and the appearance (smooth or irregular) of its border were compared. In addition, the SAE index [SAE (parenchyma) - SAE (tumor)/ SAE (parenchyma)] was histographically determined using a computerized program (PiView TM ; Mediface, Seoul, Korea). The statistics were analysed using student'st test. RESULT: Of the 24 HCC cases, 20 (83%) showed internal SAE signals, while 23 (96%) marginal signals were emitted. Of the 26 cases of metastatic adenocarcinoma, one (4%) showed internal SAE signals, while in five (19%), these signals were marginal. The tumoral border was irregular in 19 HCC lesions (79%) and smooth in 23 metastatic lesions (88%). For HCC and metastatic tumors, the mean SAE index was 0.38 +/-0.15 and 0.60 +/- 0.08, respectively (p < 0.001). CONCLUSION: Gray-scale stimulated acoustic emission can be a useful tool in differential diagnosis between heatocellular carcinoma and metastatic adenocarcinoma.
Acoustics* ; Adenocarcinoma* ; Carcinoma, Hepatocellular* ; Diagnosis, Differential* ; Humans ; Liver Neoplasms ; Microbubbles ; Prospective Studies ; Seoul

This experiment was attemptel to observe possible effects of ether, halothane and methoxyflurane on the blood sugar level of the rabbit, 5, 15, 30 and 60 minutes after start of anesthesia with ether halothane and methoxyflurane by a non-rebreathing system. Comparision was made between preanesthetic and postanesthetic levels of blood sugar and the following results were obtained. In the ether anesthesia group, the blood sugar level 15 minutes after anesthesia was increased and decreased gradualley a anesthesia was progressed. In the halothane group, the blood sugar level was increased 5 minutes after anesthesia, and then decreased more rapidly than in other groups. Blood sugar levels 60 minutes after anesthesia had returned to preanesthetic levels in all groups. As the above result shows, blood sugar levels were revealed to have a tendency to increase during induction of anesthesia, and then returned gradually to the preanesthetic level during maintenence of anesthesia.
Anesthesia ; Blood Glucose* ; Ether ; Halothane ; Methoxyflurane

Between January 1992 and December 1995, 23 patients with chronic lower back pain involving lumbar disc degeneration and spinal stenosis underwent decompression and posterior lumbar interbody fusion. Two groups of patients were studied, and clinical symptoms, neurological signs and clinical results were compared. With regard to mechanical back pain and clinical results, posterior lumbar interbody fusion was superior to decompression, but as regards leg pain and neurologic signs, the two groups were similar. Posterior lumbar interbody fusion was of considerable benefit to patients with chronic lower back pain.
Back Pain ; Decompression* ; Humans ; Intervertebral Disc Degeneration ; Leg ; Low Back Pain* ; Neurologic Manifestations ; Spinal Stenosis*

Advances in gray scale ultrasonography have increased the usefulness of their modality in the clinical diagnostic method. Major improvements in the image resolution have greatly increased the diagnostic value of renal ultrasonography. The non-invasive and safe nature of ultrasound makes this technique ideal for accurate and quick evaluation. It has been well known facts that it is very difficult to obtain precise size, shape parenchymal thickness of the kidneys by conventional radiological techniques such as retrograde pyelography, antegrade percutaneous pyelography or arteriography and also the techniques are invasive to patients comparatively. Because of its simplicity, innocuousness and accurateness, diagnostic ultrasound is quite useful in the evaluation of functionally inactive kidney and should precede or be substitute for other aggressive technique. In those kidneys which remain unseen even after massive dose of dye, the ultrasound scan should be used before retrograde ureteral catheterization is undertaken. The author measured the size of kidney longitudinally, transversely and in thickness by ultrasonogram and compared with that of excretory urogram in 60 normal healthy persons and 32 cases of hydronephrosis. The results were obtained as follows: 1. The length of right kidney on ultrasonogram (11.4+/-0.55 cm) was smaller than on excretory urogram (12.2+/-0.45 cm) and the difference was 0.8 cm (t value: 2.21, p<0.02), and the length of left kidney on ultrasonogram (11.9+/-0.42 cm) was smaller than on excretory urogram (12.6+/-0.78 cm) and the difference was 0.7 cm (t value: 2.43. p<0.02). The width of right kidney on ultrasonogram (5.4+/-0.57 cm) was smaller than on excretory urogram (6.3+/-0.61 cm) and the difference was 0.9 cm (t value: 1.75, p<0.1) and the width of left kidney on ultrasonogram (5.6+/-0.58 cm) was smaller than on excretory urogram (6.3+/-0.49 cm) and the difference was 0.7 cm (t value: 1.82, p<0.1). The parenchymal depth of right kidney on ultrasonogram (2.2+/-0.48 cm) was larger than on excretory urogram (2.1+/-0.56 cm) and the difference was 0.1 cm (t value: 2.89, p<0.001), and the parenchymal depth of left kidney on ultrasonogram (2.1+/-0.54 cm) was alike on excretory urogram (2.1+/-0.57 cm) and there was no difference (t value: 2.31, p<0.05). 2. Among the 32 cases of hydronephrosis. 17 cases of hydronephrosis could be diagnosed by excretory urogram. In mild hydronephrosis, the length of kidney on ultrasonogram (12.2+/-0.56 cm) was smaller than on excretory urogram (12.8+/-0.46 cm) and the difference was 0.6 cm, the width of kidney on ultrasonogram (6.1+/-0.27 cm) was smaller than on excretory urogram (6.4+/-0.38 cm) and the difference was 0.3 cm, and the parenchymal depth of kidney on ultrasonogram (2.1+/-0.34 cm) was alike on excretory urogram (2.1+/-0.49 cm) and there no difference. In moderate hydronephrosis, the length of kidney on ultrasonogram(13.5+/-0.47 cm) was smaller than on excretory urogram(14.2+/-0.67 cm)and the difference was 0.7cm, the width of kidneys no ultrasonogram(7.2+/-0.58 cm) was smaller than on excretory urogram(7.8+/-0.73 cm) and the difference was 0.6cm, and the parenchymal depth of kidney on ultrasonogram(1.2+/-0.57 cm) was smaller than on excretory urogram(1.47+/-0.27 cm)and the difference was 0.2 cm. In severe hydronephrosis, the length of kidney on ultrasonogram(15.7+/-0.39 cm)was smaller than on excretory urogram(16.6+/-0.53 cm) and the difference was 0.9cm, the width of kidney on ultrasonogram(8.8+/-0.46 cm) was smaller than on excretory urogram(9.5+/-0.48 cm)and the difference was 0.7 cm, and the parenchymal depth of kidney on ultrasonogram was 0.7+/-0.27 cm but could not be measured on excretory urogram. 3. Among 32 cases of hydronephrosis,15 cases of hydronephrosis were non-visualized kidney on excretory urogram. On them, the renal sized and parenchymal depth were measured accurately by ultrasonography. By reviewing the above results, the ultrasonography of kidney is useful in measurement of kidney size and can be substitute for invasive uroradiological methods in evaluation of patients with hydronephrosis.
Adult* ; Angiography ; Humans ; Hydronephrosis* ; Kidney* ; Ultrasonography* ; Urinary Catheterization ; Urinary Catheters ; Urography

No abstract available.
Animals ; Cell Line* ; Mice* ; Polymerase Chain Reaction ; Stem Cells*