1.The epidemiological studies on the filariasis in Korea II. Distribution and prevalence of malayian filariasis in southern Korea.
Byong Seol SEO ; Han Jong RIM ; Young Chan LIM ; Il Kwon KANG ; Young Ok PARK
The Korean Journal of Parasitology 1968;6(3):132-141
During 1964 to 1967, a survey of 30,534 persons for filariasis was made on all over the country with the following results: Among 24,816 draftees from all over the country in the army recruitment camp 155(0.63 %) were found infected with Brugia malayi. Cheju Do showed the highest microfilaria rate(3.5 %), North Kyongsang Do(1.4 %) the next and South Cholla Do(1.2 %) the third. Blood films from 2,308 inhabitants were examined and 407(17.6 %) showed microfilaria in Cheju Do. 30(3.1 %) out of 974 inhabitants in North Kyongsang Do were found to be infected. The microfilaria rates were 2.0 per cent for 400 inhabitants of Chindo island in South Cholla Do. However, no positive case of microfilaria was found in the inhabitants of Kokumdo among 1,820 persons examined in South Cholla Do and of Namhae island(among 165 persons examined) in South Kyongsang Do. The mean microfilarial density per 20 cu. mm of blood was 52.6 in the inhabitants of Cheju Do, 12.2 in North Kyongsang Do and 27.3 in Chindo island(South Cholla Do). Any distinct relationship between the incidence of positive cases of microfilariae and age or sex of the cases was not observed in Cheju Do. However, in Norh Kyongsang Do and South Cholla Do the microfilaria rate of the male group is higher than the one of the female group of the inhabitants. From the above survey results it turned out that filariasis was found throughout Southern Korea except Kyonggi Do and South Kyongsang Do. A total 30,534 persons examined, 601(2.0 %) were found to be infected by Brugia malayi. Therefore, it seems that there are some endemic foci of malayian filariasis in three main areas such as North Kyongsang Do, South Cholla Do and Cheju Do.
parsitology-helminth-nematoda-Brugia malayi
;
filariasis
;
epidemiology
;
Army
2.A Case of Lichen Striatus Presenting with Hypopigmented Patch.
Han Su KIM ; Byong Han SONG ; Eun Joo PARK ; In Ho KWON ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2013;51(4):300-302
No abstract available.
Hypopigmentation
;
Lichens
3.Mature Teratoma in the Cerebellar Hemisphere of an Adult.
Kwon Byong PARK ; Hyung Su PARK ; Jung Il LEE ; Yeon Lim SUH
Journal of Korean Neurosurgical Society 2007;41(3):180-181
Intracranial teratomas are diagnosed mostly in young population and usually involve midline structure. We report a case of mature teratoma in an adult patient with unusual location in cerebellar hemisphere. A 47-year-old woman presented with severe headache and nausea. Computed tomography and magnetic resonance imaging demonstrated a posterior fossa lesion with cerebellar hemispheric location not involving midline. Histological examination of surgical specimen showed fully matured representative tissues of the three germ layers confirming teratoma. This is a rare example of mature teratoma with unusual age of the patient and location.
Adult*
;
Cerebellum
;
Female
;
Germ Layers
;
Headache
;
Humans
;
Magnetic Resonance Imaging
;
Middle Aged
;
Nausea
;
Teratoma*
4.Balloon Cell Melanoma.
Byong Han SONG ; Eun Byul CHO ; Eun Joo PARK ; In Ho KWON ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2012;50(3):252-254
Balloon cell melanoma, an uncommon histopathological variant of malignant melanoma, was first described by Gardner and Vazquez in 1970. This condition is histopathologically characterized by the presence of balloon cells with varying sizes and atypical nuclei. An 84-year-old woman presented with a solitary, dome-shaped, walnut-sized, brownish nodule on the posterior aspect of the left ear with bleeding, having only detected the nodule 2 weeks prior. Histopathologically, the lobulated tumor mass revealed copious melanin pigment and many balloon cells with clear cytoplasm, atypical nuclei, and variable size. Immunohistochemically, the tumor mass showed positive reaction to S-100 protein and HMB 45 staining. We herein report a typical case of balloon cell melanoma, which developed primarily on the skin.
Aged, 80 and over
;
Cytoplasm
;
Ear
;
Female
;
Hemorrhage
;
Humans
;
Melanins
;
Melanoma
;
S100 Proteins
;
Skin
5.Fluoroscopy-induced Chronic Radiation Dermatitis.
Eun Byul CHO ; Byong Han SONG ; Eun Joo PARK ; In Ho KWON ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2012;50(7):614-617
Fluoroscopy-induced chronic radiation dermatitis (FICRD) is a cutaneous disorder that results from prolonged exposure to ionizing radiation during interventional procedures. With the expanded use of interventional procedures, there is increased fluoroscopic exposure. However, diagnosis and treatment of such disorder remain difficult. Herein, we report on a case of FICRD that occurred in the right subscapular area.
Angioplasty, Balloon, Coronary
;
Dermatitis
;
Radiation, Ionizing
6.Chronic Mucocutaneous Candidiasis Misdiagnosed as Lichen Planus.
Byong Han SONG ; Jong Hyun YOON ; Eun Joo PARK ; In Ho KWON ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Medical Mycology 2013;18(1):11-15
Chronic mucocutaneous candidiasis is a rare syndrome characterized by persistent and refractory infection of the skin, nail and mucosal tissue by yeasts of the genus Candida. A 70-year-old woman presented with the following skin lesions: ill-defined annular shaped whitish macules on the upper and lower lips accompanying dryness, pain and burning sensation, and yellowish discoloration with onycholysis of the right 4th finger nail. The upper lip lesion showed histopathologic feature of band-like infiltration of lymphocytes in the upper dermis, consistent with lichen planus. But, systemic glucocorticoid was not effective in treating erosive lip lesions. KOH examination and fungal culture of specimens from the upper lip showed hyphal elements and growth of Candida albicans, respectively. Antifungal agent was administered. After the oral medication, skin lesions were improved but there was repeated recurrence. We report a case of chronic mucocutaneous candidiasis misdiagnosed as lichen planus.
Burns
;
Candida
;
Candida albicans
;
Candidiasis, Chronic Mucocutaneous
;
Dermis
;
Female
;
Fingers
;
Humans
;
Lichen Planus
;
Lichens
;
Lip
;
Lymphocytes
;
Mucous Membrane
;
Nails
;
Onycholysis
;
Recurrence
;
Sensation
;
Skin
;
Yeasts
7.A Case of Milium Occurring on the Glans Penis.
Byong Han SONG ; Byung Chul KIM ; Eun Joo PARK ; In Ho KWON ; Kwang Ho KIM ; Kwang Joong KIM
Korean Journal of Dermatology 2011;49(12):1122-1124
Milia are small, superficial keratin cysts believed to be derived from the pilosebaceous follicle, which arise most commonly on the cheeks and eyelids. We report a case of milium occurring on the glans penis in a 18-year-old man, who had a solitary dome-shaped, 2x2 mm sized, yellowish papule. The histopathological examination showed a small keratin-filled, intradermal cyst. The cyst was lined by a stratified epithelium that was a few cell layers thick. This is the first case report in the Korean dermatological literature of milium occurring on the glans penis without coexistence of other dermatoses.
Adolescent
;
Cheek
;
Epithelium
;
Eyelids
;
Humans
;
Keratins
;
Male
;
Penis
;
Skin Diseases
8.Clinical Manifestations of Mycoplasma pneumoniae Pneumonia in Infants.
Yoo Mee CHOI ; Jeong Hee KIM ; Min Joong KWON ; Soon Seong PARK ; Dae Hyun LIM ; Byong Kwan SON
Pediatric Allergy and Respiratory Disease 2000;10(1):61-68
PURPOSE: M. pneumoniae is knwon as a common causative agents of respiratory infection in school children. But, it tends to occur in infants and younger children recently. This study was performed to evaluate the incidence and clinical manifestations of M. pneumoniae pneumonia in infants. METHOD: A total of 142 children(33 infants{Group I : Infants group; 0-2 years} and 109 children{Group II : Children group; 3-6 years}) was admitted with M. pneumoniae pneumonia from January through December 1998. We reviewed medical records and evaluated the incidence, clinical manifestations and laboratory findings. RESULT: Number of patients with M. pneumoniae pneumonia in 0 to 2 years of age(infants group) comprised 23.2% of the total in contrast to 57.1% in 3 to 6 years of age group and 19.7% in 7 to 12 years of age group. Seasonal distribution showed the highest frequency in autumn in infant and children groups(45.5% and 39.4% respectively). The most frequent symptom was cough(90.9% and 96.3%, respectively), followed by sputum(81.8% and 90.8%, respectively), fever(72.7% and 66.0%, respectively) and rhinorrhea(72.7% and 64.0%, respectively). The common physical findings on admission were crackle(84.8% and 80.7%, respectively), wheezing(30.3% and 18.3%, respectively) and throat injection(39.4% and 35.8%, respectively). WBC count was within normal range in both groups(90.9% and 89%, respectively) and CRP was lower than 0.8 mg/dL in 63.6% of infant group and 54.1% of children group. The most common radiologic finding was bronchopneumonia in both groups (47% and 38%, respectively). CONCLUSION: Number of the patients with Mycoplasma pneumoniae pneumonia in infants age from 0 to 2 years comprised 23.2% of the total. Clinical manifestations of Mycoplasma pneumonia in infants were similar to those of older children. We recommened Mycoplasma pneumoniae should be considerd as a causative agent even in infant with respiratory infection.
Bronchopneumonia
;
Child
;
Humans
;
Incidence
;
Infant*
;
Medical Records
;
Mycoplasma pneumoniae*
;
Mycoplasma*
;
Pharynx
;
Pneumonia*
;
Pneumonia, Mycoplasma*
;
Reference Values
;
Seasons
9.Cell proliferation index and the expression of p53 and Bcl-2 in tumorous and non-tumorous lesions of hepatocellular carcinoma and metastatic liver cancer.
Dong Sup YOON ; Jae Ho CHEONG ; Young Nyun PARK ; Sung Won KWON ; Hoon Sang CHI ; Byong Ro KIM
Yonsei Medical Journal 1998;39(5):424-429
In the development of a cancer, unlimited cell proliferation has been believed to play an important role. In addition, a programmed cell death called apoptosis, which is regulated by several oncogenes and tumor suppressor genes, has been suggested to be another important different pathway of carcinogenesis. Recently, several reports on cell proliferation capacity and apoptosis in the development of human liver disease have been published, but the cell proliferation index and its relationship between the expression of the bcl-2 and p53 genes involving apoptosis has not yet been discussed in view of the clinical differences of primary and metastatic liver cancer. In this study, we investigated the cell proliferation index and expression of p53 and bcl-2 in the tumorous and non-tumorous portions of both hepatocellular carcinoma and metastatic liver cancer. The expression of p53 was observed in both hepatocellular carcinoma and metastatic liver cancer, but bcl-2 expression was observed neither in hepatocellular carcinoma nor in metastatic liver cancer. In hepatocellular carcinoma, the p53 positive group showed a higher Ki-67 score (cell proliferation index) and more tumor numbers than the p53 negative group (p<0.05). In metastatic liver cancer, the results were the same as in hepatocellular carcinoma (p<0.05). However, we could not correlate the p53 expression and its prognostic significance in hepatocellular carcinoma.
Adult
;
Aged
;
Carcinoma, Hepatocellular/pathology*
;
Carcinoma, Hepatocellular/metabolism*
;
Cell Division/physiology
;
Female
;
Human
;
Liver Neoplasms/secondary
;
Liver Neoplasms/pathology*
;
Liver Neoplasms/metabolism*
;
Male
;
Middle Age
;
Protein p53/metabolism*
;
Proto-Oncogene Proteins c-bcl-2/metabolism*
10.A Case of Neurocutaneous Melanosis in a Child with Congenital Giant Nevi.
Dong Hyun KIM ; Young Se KWON ; Soon Ki KIM ; Byong Kwan SON ; In Suh PARK ; Eun Young KIM ; Choong Jae LEE
Journal of the Korean Child Neurology Society 2005;13(2):271-275
Patients with giant congenital melanocytic nevi may grow up to have melanotic tumors characterized by central nervous system involvement, termed neucutaneous melanosis. Neurocutaneous melanosis is a rare but a significant congenital syndrome characterized by large or multiple congenital melanocytic nevi and benign or malignant pigment cell tumors of the leptomeninges. The prognosis is extremely poor for symptomatic patients, even in the absence of malignant melanoma. We experienced a case of a neurocutaneous melanosis with congenital giant hairy nevi, who grew up to have progressive leptomeningeal melanomatosis and whose neurologic conditions were rapidly deteriorated to death. So we report the case with a brief review of related literature.
Central Nervous System
;
Child*
;
Humans
;
Melanoma
;
Melanosis*
;
Nevus*
;
Nevus, Pigmented
;
Prognosis