Trichoepithelioma. so named by Jarisch(1894), is a rare benign neoplasm of the skin on face and eyelid. The solitary type which is the most usual form seen in the eyelid occurs mainly in adult, on the other hand multiple type begin to appear at adolescence or puberty as a dominantly inherited condition. A 21 year-old korean female was found to have trichoepithelioma in her left lower eyelid mangm.
Adolescent ; Adult ; Eyelids ; Female ; Hand ; Humans ; Puberty ; Skin ; Young Adult

Teratomas of the fallopian tube are extremely rare, and only about 50 cases have reported in the world literature. Most cases of mature cystic tubal teratoma are asymptomatic and are discovered as an incidental finding on physical or radiologic examination, or at the time of laparatomy. We report a case of mature cystic teratoma of the right fallopian tube which was discovered during pelvic ultrasonogram for antenatal care in a 28 year old woman. Right salpingectomy was performed during cesarean section for cephalo-pelvic distortion at IUP 39 weeks. Gross examination of the right fallopian tube reveals a distended fallopian tube, measuring 8cm in length and 2cm in diameter. On section, it is filled with several small pedunculated nodules and cysts containing sebaceous materials. Microscopically the tumor was seen in continuity with the lining epithelium of mucosal folds. The majority of the tumor was composed of well differentiated mature elements of three germ layers with skin and skin appendages, mature brain tissue, bone, breast tissue, intestinal mucosa and bronchial epithelium.
Female ; Humans ; Cysts

Angioid streaks are a peculiar spoke-like distribution of dark-colored broad lines in the retinaradiating out from the optic nerve in a fashion similiar to the branching of blood vessels. It is thought to be due to breaks in the elastic lamina of Bruch's membrane. Their colour may be reddish-brown. dark-brown, grey or even in parts white. During a ophthalmoscopic examination they may be mistaken for retinal vessels. The lesion, however, lies beneath the retinal and above the choroidal vessels. Angioid streaks are most commonly seen in pseudoxanthoma elasticum, Paget's disease of bone and sickle cell anemia. Angioid streaks with pseudoxanthoma elasticum have been reported in all races and in all decades of life. The peak age lies between 30 and 50. Pseudoxnnthoma elasticum is a dermatologic condition characterized by changes in the elastic tissue of the skin. A 21 year old Korean lady with pseudoxanthoma e!asticum has been found to have angioid streaks in her both fundi.
Anemia, Sickle Cell ; Angioid Streaks* ; Blood Vessels ; Bruch Membrane ; Choroid ; Continental Population Groups ; Elastic Tissue ; Humans ; Optic Nerve ; Osteitis Deformans ; Pseudoxanthoma Elasticum* ; Retina* ; Retinal Vessels ; Retinaldehyde ; Skin ; Young Adult

Neoplasms are the most common among the diseases of the lacrimal gland. Mixed tumor is the commonest tumor of the lacrimal gland. And adenoid cystic carcinoma is the most common in malignancy of lacrimal gland. Adenoid cystic carcinoma appears past middle life and has no sexual prevalence. The first important clinical sign is proptosis with eventual displacement of the globe downwards and inwards. Limitation of ocular movements may be noted to up and out. Often the vision is not greatly disturbed. The fundus is usually normal. The adenoid cystic carcinoma is seldom rapidly fatal. Metastasis may occur in the regional lymph nodes the pre-auricular, cervical and mediastinal-and occasionally general dissemination may appear in other organs as the liver and lungs. Intracranial spread of the tumor results in death. The treatment of choice is surgical removal of the tumor. However, if they are not completely removed, it will recur repeatedly. It is important to save the eyeball when the tumor can not be removed completely. Radiation therapy may be tried preoperatively and post-operatively, but response to radiation therapy is generally unsatisfactory. A 27 year old Korean woman has been healthy until October, 1975, when she began to complain of painful progressive exophthalmos (O.D.). On physical examination, she was found to have a tender and hard mass in superior and temporal region of right orbit. Her visual acuity was 20/50(O.D.) and 20/20 (O.S.). There were no other abnormalities in her both eyes. On July 15, 1976, the surgical removal of the tumor was followed by radiation therapy. The tumor was reported to be a adenoid cystic carcinoma, She has been in good health for about 2 years since she received operation.
Adenoids* ; Adult ; Carcinoma, Adenoid Cystic* ; Exophthalmos ; Female ; Humans ; Lacrimal Apparatus* ; Liver ; Lung ; Lymph Nodes ; Neoplasm Metastasis ; Orbit ; Physical Examination ; Prevalence ; Visual Acuity

The chronic cyclitis was first described under the designation of cyclitis by Ernst Fuchs in 1892, having been described as peripheral uveitis and pars planitis. The etiopathogenic nature of chronic cyclitis has been in controversy but the role of allergy is suggested in this disease entity, The inflammatory process starts at ciliary body and peripheral chorioretina, extends to anterior chamber and vitreous. It is incidious, bilateral and recurrent, affects young individuals. This condition begins with minimal symptoms of hazy vision and vitreous opacity, may result in serious visual disturbances due to various complications including cataract, macular degeneration, retinal detachment, glaucoma and phthisis bulbi. A 50 year old man was found to have chronic cyclitis in his left eye that was treated with antituberculous agents and sub-Tenon's injection of corticosteroid agent.
Anterior Chamber ; Cataract ; Ciliary Body ; Glaucoma ; Humans ; Hypersensitivity ; Macular Degeneration ; Middle Aged ; Pars Planitis ; Retinal Detachment ; Uveitis* ; Uveitis, Intermediate*

Cutaneous smooth muscle hamartomas are benign proliferations of smooth muscle bundles within the dermis. They can be congenital or acquired, and most cases are congenital. Congenital smooth muscle hamartomas (CSMHs) usually manifest at birth as well-circumscribed, frequently hypertrichotic, hyperpigmented or skin-colored patches or plaques on trunk or extremities. We report a case of CSMH in a 10 year-old girl, who showed a localized skin-colored patch showing prominent follicular papules on the lateral aspect of her right upper arm, which were found at birth. There was no hypertrichosis and the pseudo-Darier sign was negative. This patchy follicular variant is the less common clinical type of the disease.
Arm ; Dermis ; Extremities ; Female ; Hamartoma* ; Humans ; Hypertrichosis ; Muscle, Smooth* ; Parturition

No abstract available.
Leukocytes*

Although a number of remedies like corticosteroids, retinoids, griseofulvin, PUVA, cyclosporine, antibiotics, dapsone, cyclophosphamide, surgery, methotrexate, radiation therapy, antimalarial drugs, psychotharapy and psychiatric medications have been used to treat lichen planus, there were no specific methods until now. We report herein an interesting case of lichen planus in which complete healing was achieved by griseofulvin administration. The patient was a 54-year-old male who for 3 months had variouly sized and shaped, flat-topped, scaly, violaceous papules and plaques on the whole of his body. We confirmed the patients disease as lichen planus by a histopathologic examination of a skin biopsy specimen and gave him 500mg ultramicronized griseofulvin daily in divided dosages. After 12 weeks of the medication nearly all of the skin lesions were regressed, and by 14 weeks all skin lesions had disappeared leaving hyperpigmentation. Up to now, l9 months after discontinuation of the medication, no recurrence of the disease has been noted.
Adrenal Cortex Hormones ; Anti-Bacterial Agents ; Antimalarials ; Biopsy ; Cyclophosphamide ; Cyclosporine ; Dapsone ; Griseofulvin* ; Humans ; Hyperpigmentation ; Lichen Planus* ; Lichens* ; Male ; Methotrexate ; Middle Aged ; Recurrence ; Retinoids ; Skin

No abstract available.
Blood Platelets* ; Disseminated Intravascular Coagulation* ; Platelet Activation*

Keratoconus (conical cornea) is a condition, beginning about puberty and developing mainly in females, in which the apex of the cornea thins gradually and usually bilaterally. The etiology is unknown. The presenting symptom is a reduction of the patient's vision owing to the development of a high degree of irregular myopic astigmatism. Early in the course of the disease the cornea does not look conical. The diagnosis of Keratoconus is confirmed by the distorted reflex observed with a Placido's disc and abnormal keratometer readings. In more advanced stages, signs include the obvious cone-shaped cornea and indentation of the lower lid by the cornea. By slit lamp biomicroscopy, vertical lines are noted in the deep layers of the stroma: the corneal nerve fibers are increasingly visible; and in about 50% of cases a yellow or green line is present around the base of the corn (Fleischer's ring). In advanced cases Bowman's membrane and Descemet's membrane rupture. Microscopically there is thinning of the tissue spaces between the corneal lamellae, fragmentation of the basement membrane of the comeal epithelium, fibrillation of Bowman's membrane, and folds or ruptures in Descemet's membrane. Acute hydrops may occur when Descemet's membrane ruptures. This is characterized by sudden cloudiness of vision due to imbibition of aqueous in the corneal stroma. However, as Descemet's membrane regenerates, the edema subsides. Permanent scarring may result if Bowman's membrane ruptures. Acute hydrops of the cornea was developed respectively in left eye on Oct, 1976 and in right eye on Dec, 1976 in a 13 year old Korean girl with Keratoconus O.U.
Adolescent ; Astigmatism ; Basement Membrane ; Bowman Membrane ; Cicatrix ; Cornea* ; Corneal Stroma ; Descemet Membrane ; Diagnosis ; Edema* ; Epithelium ; Female ; Humans ; Keratoconus* ; Nerve Fibers ; Puberty ; Reading ; Reflex ; Rupture ; Zea mays