1.Study on the ELISA method using monoclonal antibody for the detection of Hantaan virus.
Journal of the Korean Society for Microbiology 1992;27(3):297-305
No abstract available.
Enzyme-Linked Immunosorbent Assay*
;
Hantaan virus*
2.The Evaluation of Immunochromatographic Assay kit for Rapid Detection of Hepatitis B Surface Antigen.
Hyeong Soon SHIN ; Young Bong KIM ; Jung Woo SHIN ; Chang Kyu KIM ; Wang Sik LEE ; Han Kyeom KIM ; Kwang soon SHIN
Journal of the Korean Society of Virology 1997;27(2):137-141
We evaluated Immunochromatographic assay kit to screen HBsAg in human serum. When the reference HBsAg was applyed to ICA, HA and EIA kits, the limit of detection for HBsAg were found out to be 4, 2 and 0.25 ng/ml respectively. But ICA kit required 5 minutes to read the result whereas HA and EIA kit more than one hour. The sensitivity was 97% (29 of 30 samples) and the specificity 100% (45 samples) compared with conventional EIA. The ICA kit needs no instrument or machine to perform the test contrary to the conventional methods. Therefore, this rapid and sensitive ICA kit can be used for HBsAg-screening, especially in the emergency room and in the scene of the accident.
Emergency Service, Hospital
;
Hepatitis B Surface Antigens*
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Immunochromatography*
;
Limit of Detection
;
Sensitivity and Specificity
3.A Case of Kimura's Disease with an Unusual Location and Clinical Manifestation.
Ho Gyun LEE ; Bang Soon KIM ; Ai Young LEE ; Kwang Hyun CHO ; Yoo Shin LEE
Annals of Dermatology 1990;2(2):145-148
Kimura's disease is a chronic inflammatory condition of unknown cause. It usually appears as a painless nodule in the head and neck region often associated with regional lymphadenopathy, but there have rarely been reports of penile involvement or clinical presentation as an ulcerative plaque. We present a case of Kimura's disease occurring on the penile shaft as an ulcerative plaque in a 44-year-old man. A vesicular eruption had occurred on his penile shaft followed by an ulcerative plaque for 2 months. He had suffered from recurrent regional lymphadenopathy for 15 years and he had also exhibited intermittent eosinophilia. Histopathologic findings revealed diffuse eosinophilic infiltration in the dermis of the skin and eosmophilic abscesses in the lymphoid follicles of the mguinal lymph node. After short-term systemic steroid therapy and local injection of triamcinolone acetonide, the ulcerative plaque was healed.
Abscess
;
Adult
;
Dermis
;
Eosinophilia
;
Eosinophils
;
Head
;
Humans
;
Lymph Nodes
;
Lymphatic Diseases
;
Neck
;
Skin
;
Triamcinolone Acetonide
;
Ulcer
4.Studies on the infectivity of rickettsia tsutsugamushi in bird.
Young Woo SHIN ; Ho Yeon SONG ; Kwang Kjune KO ; Kang Soon RHEE
Journal of the Korean Society for Microbiology 1991;26(2):185-194
No abstract available.
Birds*
;
Orientia tsutsugamushi*
;
Rickettsia*
5.A Case of Adenoid Cystic Carcinoma of Bartholin's Gland.
Soon Gyu KIM ; Jin Woo SHIN ; Kwang Il KIM ; Yang Suk KIM ; Jae Seong KANG
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(2):209-212
Adenoid cystic carcinoma is a rare disease of which incidence is 10-15 % of bartholins gland carcinoma. The clinical presentation is characterized by a vulval mass that existed for a prolonged period to the onset of symptoms, usually infection, pain, and burningsensation Histologically, this tumor is characterized by cribriform pattern cell growing and perineural invasion. The obtaining of clear surgical margins is the most important aspect of treatment. Here we report a case of adenoid cystic carcinoma of the Bartholins gland with a brief review of literature.
Adenoids*
;
Carcinoma, Adenoid Cystic*
;
Incidence
;
Rare Diseases
6.Rapid Tracheal Intubation with High-dose Vecuronium.
Beum Jun CHO ; Soon Ho NAM ; Yang Sik SHIN ; Kwang Won PARK
Korean Journal of Anesthesiology 1995;28(2):245-250
For the rapid endotracheal intubation, the ideal neuromuscular blocking drug with short onset time, short duration and few side effects has so far not been found. Succinylcholine is still, inspite of its side-effects and contraindications, the standard drug of choice for rapid intubation. But, high-dose vecuronium as an alternative to succinylcholine for rapid intubation may be recommended. To compare the intubating conditions with that in succinylcholine, the onset and cardiovascular effects of high-dose vecuronium(0.3 mg/kg) were evaluated clinically with a scoring system. The results are as follows ; 1) High-dose vecuronium may provide an alternative means of achieving a rapid onset of neuromuscular blockade. 2) High-dose vecuronium shows minimal effects on cardiovascular system. In concluson, high-dose vecuronium as an alternative method for rapid endotracheal intubation may be recommended without any significant cardiovascular change if succinylcholine is contraindicated.
Cardiovascular System
;
Intubation*
;
Intubation, Intratracheal
;
Neuromuscular Blockade
;
Succinylcholine
;
Vecuronium Bromide*
7.A case of mediastinal cystic lymphangioma.
Dong Seung YEO ; Dong Il LEE ; Kwang Uk LEE ; Dae Hwan KANG ; Soon Kew PARK ; Young Kee SHIN
Tuberculosis and Respiratory Diseases 1992;39(4):361-365
No abstract available.
Lymphangioma*
;
Mediastinal Cyst*
8.Unusual Prolonged Recovery of Succinylcholine - induced Neuromuscular Block Following Neostigmin.
Yang Sik SHIN ; Mi Yung CHOI ; Soon Ho NAM ; Kwang Won PARK
Korean Journal of Anesthesiology 1992;25(1):172-176
We report a case of slow recovery of the neuromuscular block induced by succinylcholine (SCC) immediately after administration of neostigmine for the reversal of pancuronium. Left hemithyroidectomy was performed in a 4l kg female patient under general endotracheal inhalation anesthesia with 50%-nitrous oxide and 2.0%-enflurane. Four mg of pancuronium was used for muscular relaxation to facilitate the controlled ventilaion on the anesthesia ventilator. At the end of the operation, one and a half hours from the injection of pancuronium, 10 mg of pyridostigmine was administered to reverse the neuromuscular blockade. Five minutes later, 25 mg of succinylcholine was given for reintubation. Following this event, train-of-four stimuli was applied under the uncalibrated mode with Datex Relaxograph because apnea followed by SCC appeared for more than 30 minutes. Neuromuscular monitoring revealed fade to less than 50% of the T, ratio. The ventilator was applied for the recovery of neuromuscular blockade for one hour. There was no more late complications after transfer to the ward. The literature relating to this iatrogenic complication and phase II block after SCC is reviewed and discussed.
Anesthesia
;
Anesthesia, Inhalation
;
Apnea
;
Female
;
Humans
;
Neostigmine
;
Neuromuscular Blockade*
;
Neuromuscular Monitoring
;
Pancuronium
;
Pyridostigmine Bromide
;
Relaxation
;
Succinylcholine*
;
Ventilators, Mechanical
9.Histopathological Studies of 300 Cases of Non-Hodgkin's Lymphoma in Korean Patients.
Hee Jeong AHN ; Soon Hee JUNG ; Hyen Joo JEONG ; Dong Hwan SHIN ; Kwang Gil LEE ; In Joon CHOI
Korean Journal of Pathology 1988;22(3):222-231
Non-Hodgkin's malignant lymphoma is a relatively frequent lymphoreticular malignancy, and has been reported to constitute up to 5.2% of all malignant tumors in Korean patients. Various morphologic classifications of non-Hodgkin's lymphoma have been proposed, and among them, the Rappaport's classification has been most widely accepted. In 1982, a National Cancer Institute sponsored study on classification led to the creation of the Working Formulation in an attempt to resolve the controversy anddebate regarding the various classifications of non-Hodgkin's lymphoma. Angioimmunoblastic lymphadenopathy with dysproteinemia and polymorphic reticulosis are lymphoreticular proliferative disorders which have reported to transform to malignant lymphoma. The purpose of the present study is to reclassify non-Hodgkin's lymphomas according to the Working Formulation and to investigate the histopathological and immunocytochemical characteristics of angioimmunoblastic lymphadenopathy with dysproteinemia and polymorphic reticulosis. This study reviewed 300 cases of nodal and extranodal non-Hodgkin's lymphoma, 26 cases of polymorphic reticulosis, and 7 cases of angioimmunoblastic lymphadenopathy with dysproteinemia examined in the Departments of Pathology, Yonsei University College of Medicine, Youngdong Severance Hospital and Yonsei University Wonju College of Medicine from January 1977 to December 1986. In non-Hodgkin's lymphoma, each case was classified according to the Working Formulation and the Rappaport classification. All angioimmunoblastic lymphadenopathy with dysproteinemia and polymorphic reticulosis cases were subjected to histopathological analysis and a review of the clinical records. Immunocytochemical studies were done using kappa and lambda chains for B-cell markers and alpha-1-antichymotrypsin for histiocytic marker. The results obtained were as follows; 1) Among 300 cases of non-Hodgkin's lymphoma, the primarily involved tumor sites were the lymph nodes (141 cases), the gastrointestinal tract (67 cases), and the tonsils (32 cases) in descending order of frequency. 2) Using the Working Formulation, intermediategrade lymphomas occurred in 66.4% of the patients, and the most common subtype was "diffuse, large cell" (32.7%). By the Rappaport classification, 3 patients had nodular lymphomas, and "diffuse, histiocytic" was the most common subtype. 3) Infarction was present in 32 cases in which the "diffuse, lagre cell" type was most frequently associated. 4) In immunoperoxidase stains of 7 cases of angioimmunoblastic lymphadenopathy with dysproteinemia, proliferating immunoblasts revealed a polyclonal positivity for kappa and lambda chains. Atypical reticulocytes present in 26 cases of polymorphic reticulosis revealed a negativity for kappa, lambda and alpha-1-antichymotrypsin.
10.Histopathological Studies of 300 Cases of Non-Hodgkin's Lymphoma in Korean Patients.
Hee Jeong AHN ; Soon Hee JUNG ; Hyen Joo JEONG ; Dong Hwan SHIN ; Kwang Gil LEE ; In Joon CHOI
Korean Journal of Pathology 1988;22(3):222-231
Non-Hodgkin's malignant lymphoma is a relatively frequent lymphoreticular malignancy, and has been reported to constitute up to 5.2% of all malignant tumors in Korean patients. Various morphologic classifications of non-Hodgkin's lymphoma have been proposed, and among them, the Rappaport's classification has been most widely accepted. In 1982, a National Cancer Institute sponsored study on classification led to the creation of the Working Formulation in an attempt to resolve the controversy anddebate regarding the various classifications of non-Hodgkin's lymphoma. Angioimmunoblastic lymphadenopathy with dysproteinemia and polymorphic reticulosis are lymphoreticular proliferative disorders which have reported to transform to malignant lymphoma. The purpose of the present study is to reclassify non-Hodgkin's lymphomas according to the Working Formulation and to investigate the histopathological and immunocytochemical characteristics of angioimmunoblastic lymphadenopathy with dysproteinemia and polymorphic reticulosis. This study reviewed 300 cases of nodal and extranodal non-Hodgkin's lymphoma, 26 cases of polymorphic reticulosis, and 7 cases of angioimmunoblastic lymphadenopathy with dysproteinemia examined in the Departments of Pathology, Yonsei University College of Medicine, Youngdong Severance Hospital and Yonsei University Wonju College of Medicine from January 1977 to December 1986. In non-Hodgkin's lymphoma, each case was classified according to the Working Formulation and the Rappaport classification. All angioimmunoblastic lymphadenopathy with dysproteinemia and polymorphic reticulosis cases were subjected to histopathological analysis and a review of the clinical records. Immunocytochemical studies were done using kappa and lambda chains for B-cell markers and alpha-1-antichymotrypsin for histiocytic marker. The results obtained were as follows; 1) Among 300 cases of non-Hodgkin's lymphoma, the primarily involved tumor sites were the lymph nodes (141 cases), the gastrointestinal tract (67 cases), and the tonsils (32 cases) in descending order of frequency. 2) Using the Working Formulation, intermediategrade lymphomas occurred in 66.4% of the patients, and the most common subtype was "diffuse, large cell" (32.7%). By the Rappaport classification, 3 patients had nodular lymphomas, and "diffuse, histiocytic" was the most common subtype. 3) Infarction was present in 32 cases in which the "diffuse, lagre cell" type was most frequently associated. 4) In immunoperoxidase stains of 7 cases of angioimmunoblastic lymphadenopathy with dysproteinemia, proliferating immunoblasts revealed a polyclonal positivity for kappa and lambda chains. Atypical reticulocytes present in 26 cases of polymorphic reticulosis revealed a negativity for kappa, lambda and alpha-1-antichymotrypsin.