1.Clinical significance of the expression oncosuppressor gene proteins and epidermal growth factor receptor in squamous cell carcinomas of the larynx.
Kwang Yoon JUNG ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):990-1004
No abstract available.
Epidermal Growth Factor*
;
Larynx*
;
Proteins*
;
Receptor, Epidermal Growth Factor*
2.Primary malignant tumors of the ethmoid sinus.
Seung Ho LEE ; Jong Ouck CHOI ; Kwang Yoon JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):920-924
No abstract available.
Ethmoid Sinus*
3.A study for clinical application of pectoralis major myocutaneousflap.
Jong Ouck CHOI ; Kwang Yoon JUNG ; Hyoung Keon CHA
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):123-129
No abstract available.
4.A Clinical Study of the Tibial Plafond Fractures
Byung Hyun JUNG ; Chil Soo KWON ; Kwang Yoon SEO
The Journal of the Korean Orthopaedic Association 1988;23(1):49-56
The tibial plafond fractures result from an axial compression snd rotational forces causing variable degrees of metaphyseal disruption, articular damage, and malleolar displscement. It is relatively uncommon but a most difficult fracture to manage. It has been treated in a number of manners, but the best results have been occurred when stable internal fixation is accomplished using plates and screws. Basic steps in reconstruction are restoration of anatomic length of the fibula with plate fixation, reconstruction of the tibial articular surface, cancellous bone grafting of the metaphyseal defect and buttress plating of the distal tibia. The suthor analysed the 20 cases of the tibial plafond frsctures in 17 patients, which were trested at the Department of Orthopedic Surgery, Paik Hospital, Inje Medical College from Jsnuary 1983 to March 1987. The longest durstion of followup was 2 years and 4 months and shortest one was 6 months, and the aversge was one year. The results were as follows : 1. Among the 17 patients, male were 16 and female was one. 2. The major causes of injury were a fall from a height. 3. The most frequent type of fracture was type C by Ruedi and Allgower classification. 4. Regardless of the method of trestment the type A and B were in good and fair result, but the type C were fair in 4 cases and poor in 8 cases. There were 7 cases of snkle fusion in poor group. 5. It is important to remind the basic steps in reconstruction and applied in sn individual csse especially in type C. If anatomic reconstruction of the joint surface can be restored and stable fixation achieved, esrly motion of the ankle joint is made possible. This early motion reduces stiffness of the ankle and win yeild the most sstisfying result. But the anatomic reduction of ank1 joint is difficult to be obtained in each case especially in type C and may consider an ankle fusion.
Ankle
;
Ankle Joint
;
Bone Transplantation
;
Classification
;
Clinical Study
;
Female
;
Fibula
;
Follow-Up Studies
;
Humans
;
Joints
;
Male
;
Methods
;
Orthopedics
;
Tibia
5.Experimental study of interstitial Nd:YAG laser hyperthermia on rabbit tongue mucosa.
Youn Woo NAM ; Kwang Yoon JUNG ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):977-989
No abstract available.
Fever*
;
Mucous Membrane*
;
Tongue*
6.Collision carcinoma in a metastatic neck node.
Sun Hee LEE ; Kwang Yoon JUNG ; Jong Ouck CHOI ; Sang Ae YOON ; Nam Hee WON
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(3):410-413
No abstract available.
Neck*
7.Expression of Matrix Metalloproteinase and Tissue Inhibitor of Metallproteinase in Breast Carcinoma Related to Angiogenesis and Invasion.
Yoon Jung CHOI ; Woo Hee JUNG ; Hy De LEE ; Kwang Gil LEE
Korean Journal of Pathology 2000;34(9):652-664
Among the enzymes which are responsible for basement membrane breakdown, matrix metalloproteinases (MMP) form a family of neutral proteases that are regulated at the levels of gene transcription, proenzyme activation by the cleavage of protein, and the inhibition of the active enzyme by tissue inhibitors of matrix metalloproteinases (TIMP). Recent reports have demonstrated that the expression of these proteolytic enzymes are elevated in several solid tumors and that it can be associated with invasiveness and poor prognosis. We examined the expression of MMP-2, MMP-9, TIMP-1 and TIMP-2 by immunohistochemistry in 160 cases of infiltrating ductal carcinoma. And we compared these data with the established prognostic parameters - tumor size, nodal status, clinical stage, hormonal receptor status, microvessel density, and TGF-beta1 expression in order to evaluate how MMP and TIMP expression are associated with breast cancer progression and prognosis. Microvessel density in invasive breast carcinoma was significantly correlated with tumor size and recurrence (p<0.05). The immunohistochemical expression of TGF-beta1 was significantly associated with tumor size, lymph node metastasis, and clinical stage (p<0.05). The microvessel density was significantly correlated with TGF-beta1 expression in more than 50% of tumor cells. The immunohistochemical expression of MMP-2 and MMP-9 were significantly correlated with nodal metastasis and absence of immunoreactivity for estrogen and progesterone receptors. The immunohistochemical expression of TIMP-1 was inversely correlated with clinical stage and microvessel density while that of TIMP-2 was inversely correlated with clinical stage (p<0.05). Small size of tumor, presence of progesterone receptor, highly differentiated histologic grade, and absence of immunoreactivity for MMP-9 were significantly associated with higher survival rate, but in multivariate analysis only tumor size and MMP-9 expression appeared to affect survival independently.
Basement Membrane
;
Breast Neoplasms*
;
Breast*
;
Carcinoma, Ductal
;
Estrogens
;
Humans
;
Immunohistochemistry
;
Lymph Nodes
;
Matrix Metalloproteinases
;
Microvessels
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Peptide Hydrolases
;
Prognosis
;
Receptors, Progesterone
;
Recurrence
;
Survival Rate
;
Tissue Inhibitor of Metalloproteinase-1
;
Tissue Inhibitor of Metalloproteinase-2
;
Transforming Growth Factor beta1
8.Nasopharyngeal teratoma.
Jeung Cheul CHOI ; Jung Hyuck SUH ; Jong Ouck CHOI ; Kwang Yoon JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):818-821
No abstract available.
Teratoma*
9.A case of hypopharyngeal diverticulum.
Kwang Yoon JUNG ; Jong Ouck CHOI ; Yin Gyo JUNG ; Hong Kyun YOO
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):157-161
No abstract available.
Diverticulum*
10.Fine needle aspiration cytology of proliferative fasciitis.
Yoon Jung CHOI ; Sang Yeop YI ; Woo Ick YANG ; Soon Hee JUNG ; Kwang Gil LEE
Korean Journal of Cytopathology 1993;4(1):52-56
No abstract available.
Biopsy, Fine-Needle*
;
Fasciitis*