1.Posterior Dual Plating for Distal Shaft Fractures of the Humerus.
Chul Hyun CHO ; Kwang Yeung JEONG ; Beom Soo KIM
Journal of the Korean Fracture Society 2017;30(3):117-123
PURPOSE: To evaluate the results and efficacy of posterior dual plating for distal shaft fractures of the humerus. MATERIALS AND METHODS: We retrospectively analyzed 12 patients, who underwent open reduction and internal fixation using posterior dual plating for distal shaft fractures of the humerus, between July 2007 and July 2015, with at least 6 months of follow-up. After locating the radial nerve without dissection via posterior triceps splitting, the fracture was stabilized using a short 3.5 mm locking compression plate. Then additional fixation, using a long 3.5 mm locking compression plate, was performed. The clinical outcomes were assessed in accordance with the Mayo Elbow Performance Index (MEPI) scoring system, and the radiological outcomes were assessed using serial plain radiographs. RESULTS: Eleven patients (91.7%) had bony union, and the mean union period was 13.9 weeks. In one patient, delayed union was treated by autogenous iliac bone graft at 8 months after surgery, which resulted in bony union. The mean MEPI score was 95.8, and the clinical outcomes were excellent in 9 patients and good in 3 patients. Postoperative complications included 1 elbow stiffness by heterotopic ossification and 1 temporary radial nerve palsy. One patient with temporary radial nerve palsy was completely recovered within the first 4 days after surgery. CONCLUSION: Posterior dual plating for distal shaft fractures of the humerus revealed satisfactory clinical and radiological outcomes. It can be a useful alternative to provide stable fixation without the need for a dissection of the radial nerve.
Elbow
;
Follow-Up Studies
;
Humans
;
Humerus*
;
Ossification, Heterotopic
;
Paralysis
;
Postoperative Complications
;
Radial Nerve
;
Retrospective Studies
;
Transplants
2.Dislocation of the Shoulder with Ipsilateral Humeral Shaft Fracture: A Case Report.
Chul Hyun CHO ; Kwang Yeung JEONG
Journal of the Korean Fracture Society 2010;23(4):382-385
Dislocation of the shoulder with ipsilateral humeral shaft fracture is very rare, but serious injury that requires emergent care. There have been approximately 20 cases reported in the English literature, but it has never been reported in Korea. We report a case of dislocation of right shoulder with ipsilateral humeral shaft fracture which was successfully treated by closed reduction of the shoulder under general anesthesia and internal fixation with antegrade interlocking intramedullary nailing for the humeral shaft fracture.
Anesthesia, General
;
Dislocations
;
Fracture Fixation, Intramedullary
;
Korea
;
Shoulder
;
Shoulder Dislocation
3.Expression of Wnt 1 and beta-catenin in epithelial ovarian cancer.
Kyoung Ran YIM ; Chan LEE ; Yong Min KIM ; Kwang Il KIM ; Seung Jo KIM ; Youn Yeung HWANG ; Seon Yeong LEE ; Young Jeong NA ; Sang Geun JEONG ; Yoe Un OH
Korean Journal of Obstetrics and Gynecology 2008;51(9):974-981
OBJECTIVE: We were trying to identify the expression of Wnt 1 and beta-catenin in normal ovarian epithelium and epithelial ovarian tumor. METHODS: We used archival formalin-fixed and paraffin-embedded tissues from Comprehensive Gynecologic Cancer Center and the Department of Pathology at Bundang CHA Hospital from 2000 to 2005. Immunohistochemical staining for Wnt 1 and beta-catenin was performed on the ovarian epithelial tissues. Statistical analyses were performed with SPSS 10.1 for Windows and significance was defined as P<0.05. RESULTS: Of 114 cases, the cases were composed of 54 carcinomas, 40 borderline tumors, 12 benign tumors and 8 normal control ovarian tissues. Abnormal nucleocytoplasmic expression of beta-catenin was found in 4 endometrioid carcinomas. The nuclear expression of beta-catenin was found especially in the components of the endometrioid carcinoma (28.6%, P<0.05). Wnt 1 was overexpressed in all 9 clear cell carcinomas, but not frequent in the other types of malignant tumors (P<0.05). We found a statistically significant correlation between beta-catenin nuclear localization and endometrioid carcinomas. And we found a significant correlation between Wnt 1 expression and clear cell carcinomas. CONCLUSION: It does not seem that Wnt 1 over expression directly provoke the nuclear localization of beta-catenin. But, deregulation of beta-catenin and Wnt 1 may play a role in the pathogenesis of ovarian epithelial carcinogenesis of endometriod carcinoma and clear cell carcinoma. Evaluating this avenue of regulation of beta-catenin and Wnt protein in ovarian epithelial carcinoma may provide a new direction for early diagnosis and treatment in ovarian epithelial carcinoma and provide opportunities for making a certain biomarkers.
beta Catenin
;
Carcinoma, Endometrioid
;
Early Diagnosis
;
Epithelium
;
Neoplasms, Glandular and Epithelial
;
Ovarian Neoplasms