1.A Case of 13 Ring Chromosome Syndrome.
Chan Jeong PARK ; Byeong Il LIM ; Hyeon Jeong CHO ; Kih Yeon SONG ; Kwang Woo KIM
Journal of the Korean Child Neurology Society 1998;5(2):383-387
We have experienced a case of 13 ring chromosome in a 40-month-old girl who demonstrated psychomotor retardation with delayed speech, growth retardation, hearing loss(left), microcephaly, trigonocephaly with flat occiput, hypertelorism, epicanthal folds, microophthalmia, broad prominamt nasal bridge, high arched palate, micrognathia, large auricles and other anomalies. Cytogenetic studies of peripheral blood lymphocytes with differential staining of chromosomes revealed 46, XX, r13. Her parents' karyotypes were normal. We reported the case with the review of the associated literatures.
Child, Preschool
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Craniosynostoses
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Cytogenetics
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Female
;
Hearing
;
Humans
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Hypertelorism
;
Karyotype
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Lymphocytes
;
Microcephaly
;
Palate
;
Ring Chromosomes*
2.Solitary pulmonary metastasis of gestational choriocarcinoma.
Se Hwa YOO ; Zin Mock YOO ; Jae Yeon CHO ; Kwang Ho IN
Tuberculosis and Respiratory Diseases 1992;39(1):79-82
No abstract available.
Choriocarcinoma*
;
Female
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Neoplasm Metastasis*
;
Pregnancy
3.Clinical Comparison of Neonatal Urinary Tract Infection Caused by Klebsiella pneumoniae Versus Non - klebsiella pneumoniae.
Byeong Il LIM ; Hyeon Jeong CHO ; Ji Yeon HONG ; Woo Ki LEE ; Kwang Woo KIM
Journal of the Korean Society of Neonatology 1999;6(2):193-200
PURPOSE: The purpose of this study was to describe the clinical characteristics of neonatal urinary tract infection (UTI) caused by Klebsiella pneumoniae and non- Klebsiella pneumoniae UTI. METHODS: We compared clinical characteristics of 84 neonatal patients with UTI caused by Klebsiella pneumoniae who were hospitalized at the Department of Pediatricsat Han Dong University, Sunlin Hospital during the period between May, 1994 and August, 1998. The cases were divided into two groups depending upon causative organisms' Klebsiella pneumoniae UTI vs non-Klebsiella pneumoniae UTI, and the clinical characteristics of these groups were compared. RESULTS: Escherichia coli was the most common bacterial pathogen causing neonatal UTI, followed by Klebsiella pneumoniae. There was no significant difference in the sex distribution of Klebsiella pneumoniae UTI, but non-Klebsiella pneumoniae UTI showed male predominence. There were no significant differences in the incidences of hematologic, urologic, radiologic findings and perinatal complications in between these 2 groups. CONCLUSION: Klebsiella pneumoniae is the second most common pathogen causing neonatal UTI. There were no specific differences in the laboratory, symptomatologic, and radiologic findings in these two groups.
Escherichia coli
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Humans
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Incidence
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Klebsiella pneumoniae*
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Klebsiella*
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Male
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Pneumonia
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Sex Distribution
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Urinary Tract Infections*
;
Urinary Tract*
4.c-erbB-2 Oncoprotein Expression in Ductal Carcinoma in situ and Paget's Disease of the Breast.
Jung Yeon KIM ; Kyung Ja CHO ; Seung Sook LEE ; Shin Kwang KHANG ; Nam Sun PAIK
Korean Journal of Pathology 1996;30(11):972-980
A clinico-pathologic study with an immunohistochemical examination for c-erbB-2 expression in 54 cases of ductal carcinoma in situ and 16 cases of Paget's disease of the breast was performed. c-erbB-2 oncoprotein overexpression was observed in 45% (24/54) and 88% (14/16) of ductal carcinoma in situ and Paget's disease, respectively. The overexpression of c-erbB-2 oncoprotein was significantly correlated with the nuclear grade of tumors and inversely with the status of the estrogen receptor. c-erbB-2 was positive in 4 out of 5 patients with metastasis to axillary lymph nodes and 3 out of 4 patients who died of the disease. Prognostic significance of c-erbB-2 oncoprotein in ductal carcinoma in situ was highly suggested. The expression of c-erbB-2 oncoprotein in Paget's disease was well correlated with coexisting infiltrating or in situ ductal carcinoma. The high positive rate of c-erbB-2 oncoprotein in ductal carcinoma with Paget's disease could be understood with a recent hypothesis that c-erbB-2 oncoprotein is involved in promotion of cell motility and the spread of carcinoma cells.
Neoplasm Metastasis
5.Three Cases of Porokeratosis of Mibelli Treated with 5% Imiquimod Cream.
Je Ho YEON ; Hyun Sun PARK ; Kwang Hyun CHO
Korean Journal of Dermatology 2007;45(9):942-946
Porokeratosis is a disorder of epidermal keratinization that is histologically characterized by the presence of cornoid lamella. Many treatment modalities have been used, such as, surgical excision, cryosurgery, CO2 laser, oral etretinate, topical 5-fluorouracil and keratolytics. However, universal treatment guidelines have never been established. We tried 5% imiquimod cream on three patients who have porokeratosis of Mibelli which are intractable to other previous treatment modalities. Two of them showed a marked and moderate improvement, respectively. But the third patient exhibited only slight response. Herein we report our treatment experience and review the related literature.
Acitretin
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Cryosurgery
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Etretinate
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Fluorouracil
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Humans
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Lasers, Gas
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Porokeratosis*
6.A clinical analysis of surgical mortality.
Woon Yeon HONG ; Nam Cheon CHO ; Kwang Soo YOON ; Dae Sung KIM ; Byoung Seon RHOE ; Soo Yong KIM
Journal of the Korean Surgical Society 1993;45(5):854-861
No abstract available.
Mortality*
7.Role of Cytologic Scoring System in Minimizing "Gray Zone" in Breast Aspiration Cytology.
Jung Yeon KIM ; Kyung Ja CHO ; Seung Sook LEE ; Shin Kwang KHANG
Korean Journal of Cytopathology 1996;7(1):12-22
Fine needle aspiration(FNA) has been quite successful in identifying benign and malignant breast lesions, but a "gray zone" exists. A total of 697 FNAs of breast were performed at Korea Cancer Center Hospital for a period of one year. One hundred and eleven of the 697 FNAs were diagnosed as atypical or suspicious for malignancy. Among them, we reviewed 74 FNAs, in which histologic diagnoses were made, and applied cytologic grading system proposed by masood et al.(1990) to evaluate the usefulness of this system in minimizing the size of gray zone. Technical problem was responsible for equivocal diagnoses in 19 FNAs. Of the remaining 55 FNAs, 18 were benign and 37 were mali. Among benign conditions, fibroadenoma(5 cases) and fibrocystic disease with fibroadenomatous feature(3 cases) constituted the largest groups. The majority of malignant conditions were infiltrating ductal carcinoma(29 cases); however, those low grade carcinomas including tubular carcinoma(3 cases), cribriform carcinoma(2 cases), and mucinous carcinoma(2 cases) occupied a relatively large proportion Cytologic grading system was quite useful in minimizing the size of gray zone. The scores of 27 out of 29 usual infiltrating ductal carcinomas belonged to the group of cytologic malignancy, however, only 2 out of 7 low grade carcinomas got scores of malignancy. FNA from fibroadenoma or fibrocystic disease with fibroadenomatous features showed a tendency toward high scores. Experience of the cytopathologist and famillarity with cytologic alteration in breast disease cannot be overemphalized.
Breast Diseases
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Breast*
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Carcinoma, Ductal
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Diagnosis
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Fibroadenoma
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Korea
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Mali
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Mucins
;
Needles
8.Delivery of the elderly primipara.
Joo Yeon CHO ; Kwang Yul CHA ; Jung Jin KOO ; Moon Jong KIM ; Dong Hee CHOI ; Kyung Sub CHA
Korean Journal of Obstetrics and Gynecology 1991;34(9):1313-1321
9.A Study on Anxiety, Depression, Repression and Coping Strategy of Deliquent Adolescents.
Jae Kwang LEE ; Tae Won CHIN ; Ju Yeon CHO
Journal of Korean Neuropsychiatric Association 1998;37(3):493-500
In order to investigate the level of anxiety, depression and repression, and the coping style in response to the stress of the delinquent adolescents, we examined 158 delinquent adolescents and 60 student adolescents using anxiety scale, depression scale, repression sensitivity scale and coping scale. Data were processed by IBM PC AT computer using SPSS program and were statistically analyzed by ANOVA. The level of anxiety, depression and repression of delinquent adolescents was significantly higher and the score of maladaptive coping scale was significantly higher than those of student adolescents. In conclusion, delinquent adolescents were more anxious, depressive, repressive, and more maladaptive than student adolescents.
Adolescent*
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Anxiety*
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Depression*
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Humans
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Repression, Psychology*
10.Arthrocopic Reconstruction of the Posterior Cruciate Ligment: The Effects of femoral attachment points and knee flexion angles at the time of graft fixation on posterior stability
Sung Il BIN ; Key Yong KIM ; Woo Shin CHO ; Ki Kwang CHEONG ; Woo Yeon HWANG ; Jong Hi PARK
The Journal of the Korean Orthopaedic Association 1995;30(5):1164-1170
The purpose of this study is to compare the effects of the femoral attachment points of the graft and knee flexion angles at the time of graft fixation on stability of posterior cruciate ligament reconstruction. We analyzed the posterior stability of the knee on 23 patients(24 knees) with posterior cruciate ligament injury whose posterior cruciate ligament had been reconstructed arthroscopically and followed for minimum 1 year period at Asan Medical Center from May 1992 to June 1994. The patients were divided into the two groups according to femoral attachment points of the graft and knee flexion angles at the time of graft fixation. The distance from the junction of the intercondylar notch with trochlear groove of the femoral attachment points and knee flexion angles were 11mm and 0°-30° in group A and 7mm and 70°-90° in group B, respectively. 11 knees were included in group A and 13 knees in group B. Posterior stability was determined by difference in posterior tibial translation between the injured and the opposite knee with Telos device. In group A, 5 cases were at the range of 0-2mm, 3 cases 3-5 mm, 3 cases 6-10mm. In group B, 10 cases were at the range of 0-2mm and 3 cases 3-5mm, respectively. Differences in posterior tibial translation on average were 3.6mm and 1.7mm in group A and B, respectively. Conclusively, arthroscopic postrior cruciate ligament reconstruction with femoral attachment point at 7mm from the junction of interconlylar notch with trochlear groove and 70°
Chungcheongnam-do
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Humans
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Knee
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Ligaments
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Posterior Cruciate Ligament
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Transplants