No abstract available.
CREST Syndrome* ; Nifedipine

We report. herein a case of pruritic urticatial papules and plaques of pregnancy in a Z8-year-old primigravida. She had the urticarial papules and plaques on the abdomen and thighs, which developed at 30th week of pregnancy. She was treated with topical fluorinated steroid and chlorpheniramine, 6mg/ day. The itching sensation was relieved within 24 hours after the therapy and the skin lesions resolved after delivery.
Abdomen ; Chlorpheniramine ; Pregnancy* ; Pruritus ; Sensation ; Skin ; Thigh

We report a case of morphea profunda in a 21-year-old male who had diffuse brown sclerotic plaques on his extremities. Laboratory findings showed peripheral eosinophilia and an increased titers for anti-DNA and anti-nuclear antibodies. Histopathologic findings showed diffuse fibrosis and a thickening of the lower dermis and subcutaneous tissue. He has been treated with hydroxychloroquine 400mg per day and the sclerosis of the skin improved.
Antibodies ; Dermis ; Eosinophilia ; Extremities ; Fibrosis ; Humans ; Hydroxychloroquine ; Male ; Scleroderma, Localized* ; Sclerosis ; Skin ; Subcutaneous Tissue ; Young Adult

Primary localized cutaneous amyloidosis comprises macular, papular and rare nodular amyloidosis. Macular and papular amyloidosis are considered as different manifestations of the same disease process and can occur in the same patient, which is known as biphasic amyloidosis. Although most cases of primary cutaneous amyloidosis occur sporadically, some cases have been reported to have familial incidence with papular, biphasic or rarely macular amyloidosis. We report a case of a family in which a mother and her son have brown hyperkeratotic pruritic papules on both upper and lower extremities. The skin lesions initially began as macules on the shins in the second or third decade, but gradually spread with increasing papules and pigmentation. They had no kind of manifestation suggesting systemic amyloidosis. A skin biopsy specimen disclosed amyloid deposition in papillary dermis.
Amyloidosis* ; Biopsy ; Dermis ; Humans ; Incidence ; Lower Extremity ; Mothers ; Pigmentation ; Plaque, Amyloid ; Skin

Primary localized cutaneous amyloidosis comprises macular, papular and rare nodular amyloidosis. Macular and papular amyloidosis are considered as different manifestations of the same disease process and can occur in the same patient, which is known as biphasic amyloidosis. Although most cases of primary cutaneous amyloidosis occur sporadically, some cases have been reported to have familial incidence with papular, biphasic or rarely macular amyloidosis. We report a case of a family in which a mother and her son have brown hyperkeratotic pruritic papules on both upper and lower extremities. The skin lesions initially began as macules on the shins in the second or third decade, but gradually spread with increasing papules and pigmentation. They had no kind of manifestation suggesting systemic amyloidosis. A skin biopsy specimen disclosed amyloid deposition in papillary dermis.
Amyloidosis* ; Biopsy ; Dermis ; Humans ; Incidence ; Lower Extremity ; Mothers ; Pigmentation ; Plaque, Amyloid ; Skin

Bezoyl peroxide, a powerful oxidizing agent, has been uaed topically in the treatment of acne vulgaris as a cream or lotion and has been shown to he effective for this codition. In 1972 Fulton emphaaized the importance of the vehicles used to obtain. maximum potential of benzoyl peroxide and for this, the gel formulation has been examined in many clinical trials. The present study was undertaken to evaluate the therapeutic effect of Fanoxyl 2.5, a 2.5% . benzayl peraxide gel, in patients with acne vulgaris. A total of 31 patients entered this study at the Departrnent of Dermatology, Jeoul National University Hospital rluring 3 rnanths period, from Decemher, 1978 through February, 1979, All patienta were instructed to apply Fanoxyl 2.5' on their affected areas once or twice a day and the nurnber of lesions on two or three t fixed areas were counted before and onee weekly after initation of the treatment. The reaults observed in the 3I patients were as follaws; 1. The percentage decrease in total nurnber of lesions in 4 weeks after treatment was 56.9%. 2. The authors could follow up for 6 weeks in 6 cases. In 6 case, the mean percentage in total number of lesions in 6 weeks after treatment was 81.7%. 3. Clesed and open eomedones were gradually eliminated; and their numbers were decreased in 4 weeks after treatment by 46.5% and 56.8% respeetiveIy. The papules were rapidly eliminated and their numbers were decreased in 4 weeka, after treatment by 79.8%. 4. Although most patients felt a mild burning sensation and tightness at the begining of the treatment, only a minority of the patients complained of discomfort due to pain(l case), erytherna(l case), tightness(2 cases),burning sensation (1 case), scaling(1 case). But all were tolerable without taking any specific measures or discontinuance of application. In one case, contact dermatitis developed after 4 weeks treatment. The authors concluded through this experiment that Panoxyl 2.5' (2.5% benzoyl peroxide gel) is a very effective local therapeutic agent in the treatment of acne vulgaris patients.
Acne Vulgaris* ; Benzoyl Peroxide* ; Burns ; Dermatitis, Contact ; Dermatology ; Follow-Up Studies ; Humans ; Sensation

No abstract available.
Korea* ; Lung Neoplasms* ; Lung*

BACKGROUND: Chronic cutaneous lupus erythematosus(CCLE) is a well-known disease entity. But there has been no data about its clinical behavior and histopathologic features in Korea. OBJECTIVES: This study was conducted to elucidate the clinical, laboratory, and histopathologic features of CCLE, and the relationship between CCLE and SLE. MATERIALS AND METHODS: We investigated 48 cases of CCLE that visited the department of dermatology at the Seoul National University Hospital from January 1990 to June 1997. Medical records and biopsy slides were reviewed.
Biopsy ; Dermatology ; Korea ; Lupus Erythematosus, Cutaneous* ; Medical Records ; Seoul

In temporal clear corneal incision cataract surgery, it is essential to change the equipment and personnel between right eye and left eye. To obtain an advantages of clear corneal incision without going through the hassles and same effect of postoperative astigmatism and visual acuity, we sat at 10 o`clock orientation on patient`s head(right handed surgeon)and performed lateral clear corneal incision on the right eye and medial clear corneal incision on the left eye. Temporal clear corneal incision in right eye(Group 1)and medial clear corneal incision in left eye(Group 2)were performed in randomly selected 20 eyes in each group by one surgeon between June 1997 and October 1997 at Dongguk University Medical Center. Preoperative corneal astigmatism , surgically induced corneal astigmatism and changes of visual acuity were analyzed at 1 week, 2 weeks, 4 weeks, 2 months, 3 and 6 months postoperatively using corneal videokeratography(EYESYS Technology)and visual acuity chart projector(Topcon ACP-7). Postoperative uncorrected visual acuities were 20/40 or better in 75%(15 eyes)in group 1 and 70%(14 eyes)in group 2. In preoperative corneal astigmatism, there was no statistical significance between the two groups (P>0.05)(Group 1: 0.58+/-0.28D, Group 2: 0.59 +/-0.17D). In surgically induced corneal astigmatism, we found there was statistically significant difference between the two groups(P<0.05)(Group 1: 1. 26+/-0.61D, Group 2: 1. 64+/-0.34D)at 1 week postoperatively, but at 6months postoperatively, there was no statistically significant difference between the two groups(P>0.05)(Group 1: 0.87+/-0.59D, Group 2: 1. 14+/-0.58D). In conclusion, medial clear corneal incision did not need to change the personnel and equipment from case to case and the nose didn`t get in the way in medial approach. We consider that medial clear corneal incision is recommendable procedure because there were no significant differences in postoperative visual acuity and surgically induced astigmatism at 6 months postoperatively between the two groups.
Academic Medical Centers ; Astigmatism ; Cataract* ; Hand ; Nose ; Visual Acuity

We report herein a case of pityriasis lichenoides et variloiformis acuta in a 48- year-old man, who has wide spread erythematous macule, papule, vesicle, hemorrhagic vesicle and reddish-brown crust on the neck, trunk, axillae and both extremities. He was treated successfully with tetracycline 2. 0 gm a day for 4 weeks.
Axilla ; Extremities ; Neck ; Pityriasis Lichenoides* ; Pityriasis* ; Tetracycline