1.Flow cytometric DNA analysis of primary bone tumor.
The Journal of the Korean Orthopaedic Association 1993;28(3):1274-1281
No abstract available.
DNA*
2.Pulmonary Lymphangiomyomatosis: A case report.
Mi Seon LEE ; Kwang Sun SUH ; Kyoung Joo LEE
Korean Journal of Pathology 1992;26(1):88-91
Pulmonary lymphangiomyomatosis is a rare disease of haphazard overproliferation of smooth muscle from perilymphatics, peribronchial and perivascular regions of the lung that leads to chylous effusion, hemoptysis, spontaneous pneumothorax and pulmonary insufficiency. The disease only affects women of child-bearing age. There is presently no successful therapy and most of the patients die within 10 years of diagnosis. We experienced a case of pulmonary lymphangiomyomatosis in a 30-year-old woman who had suffered from three episodes of spontaneous pneumothorax for 4 years. Open lung biopsy was performed. Microscopically, abnormal excess proliferation of smooth muscle tissue was identified in the wall of perivascular lymphatic channels as well as around small bronchi, and more distal air spaces. Varying sized cytic spaces Iined by cuboidal cells were also present. Tamoxifen, given if February 1991, did not influence the course of her disease. She died of respiratory failure at age of 31 in April 1991.
Female
;
Humans
;
Biopsy
3.Adrenocortical Adenoma: A report of 7 Cases.
Mi Seon LEE ; Dae Hyun BAEK ; Kwang Sun SUH
Korean Journal of Pathology 1988;22(4):415-423
Primary tumors of the adrenal cortex are comparatively rare. In the medical literature they are most frequently reported as single case. Because of their infrequent occurence some features of their clinical behavior and pathologic anatomy are not widely known. For this reason the recording of the 7 cases from the Department of Pathology, School of Medicine, Chungnam National University is thought to be worth while. Of the seven tumors, five were associated with primary aldosteronism, one Cushing's syndrome, and the remaing one virilizing syndrome. All were benign. Females were affected more frequently than males. Adrenocortical adenomas tend to be small, weighing less than 42 gm. The tumors associated with primary aldosteronism were composed of zona fasciculata-like cells and "hybrid" cells. The tumor with Cushing's syndrome consisted of zona reticularis-like cells. The tumor with virilizing syndrome consisted of zone reticularis-like cells.
Female
;
Humans
;
Adenoma
4.Abdominal desmoid tumor transperitoneally invading colon & small bowel.
Ji Young SUL ; Seung Moo NOH ; Kwang Sun SUH
Journal of the Korean Surgical Society 1993;44(1):146-150
No abstract available.
Colon*
;
Fibromatosis, Aggressive*
5.Flow Cytometric DNA Analysis in Thyroid Neoplasms: With Emphasis on the Correlation between Ploidy Level and Pathologic Features.
Young Tae KIM ; Jin Man KIM ; Kwang Sun SUH ; Jin Sun BAE
Korean Journal of Pathology 1995;29(2):127-135
Nuclear DNA content in 31 cases of thyroid neoplasm was determined by flow cytometry with the use of paraffin-embedded archival tissue. DNA aneuploidy was found in 6 cases (19.4%) of the 31 thyroid neoplasms; such as 2 of 8 (DI=1.16, 1.56) follicular adenomas, 1 of 6 (DI=1.10) follicular carcinomas, 1 of 15 (DI=1.18) papillary carcinomas and 2 of 2 (DI=1.76, 2.07) medullary carcinomas. The remaining tumors were diploid. No significant difference between follicular adenomas and carcinomas was detected with respect to the S phase fraction(SPF). In the papillary carcinoma group the SPF was higher than in the follicular neoplasm group, but it was statistically insignificant. Regional lymph node metastasis was present in 8 of 15( 53.3%) papillary carcinomas but absent in all of the 14 follicular neoplasms. In the medullary carcinoma group one case showed regional node metastasis at the time of resection and the other developed metastasis 11 months after surgical removal of the primary lesion. In this study tumors predominantly composed of Hurthle cells were found to have a significantly higher D.I. than those with few or no Hurthle cells. No significant difference was found between tumors with metastasis and those without metastasis.
Adenoma
;
Neoplasm Metastasis
6.Malignant Fibrous Histiocytoma of the Heart: A case report.
Mi Seon LEE ; Kyu Sang SONG ; Kwang Sun SUH ; Dae Young KANG ; Young LEE
Korean Journal of Pathology 1988;22(2):138-144
A case of a 58-year-old man with malignant fibrous histiocytoma (MFH) of the right ventricle is reported light and electron microscopically. This is the first case of MFH of the heart in the Korean literature. A tendency for malignant fibrous histiocytoma of the heart to occur in the left atrium of young women is suggested; this sarcoma's usual location is in the soft tissue of elderly men. The tumor consisted of spindle cells arranged in a focal storiform patterns, clusters or sheets of histocyte-like cells, benign and malignant giant cells, inflammatory cells, scattered mitotic figures and anaplasia of stromal cells. In ultrastructure the constituent of cells of the tumor are primitive mesenchymal cells, histiocytoid cells and fibroblast like cells including giant cells.
Female
;
Male
;
Humans
7.Primary Ovarian Leiomyoma with Cystic Degeneration: A Case Report.
Journal of the Korean Radiological Society 2000;42(2):323-326
Leiomyoma of the ovary is a very rare benign tumor which is usually found incidentally on routine pelvic examination, or during surgery or autopsy. We report a case of ovarian leiomyoma in a 46-year-old woman in whom a lower abdominal mass was detected. A multiloculated and multiseptated mainly cystic mass in the left adnexa was revealed by computed tomography, and was thought to be an ovarian mucinous cystadenoma. Surgical pathology, however, demonstrated that the mass was a vascular leiomyoma originating from the left ovary.
Angiomyoma
;
Autopsy
;
Cystadenoma, Mucinous
;
Female
;
Gynecological Examination
;
Humans
;
Leiomyoma*
;
Middle Aged
;
Ovary
;
Pathology, Surgical
8.Neuroendocrine Carcinoma of the Gallbladder Arising as Double Tumor.
Dae Hyun BAEK ; Seong Ki MIN ; Jin Man KIM ; Kwang Sun SUH ; Dae Young KANG
Korean Journal of Pathology 1990;24(3):299-303
Pleomorphic (undifferentated) carcinoma is a rare histologic type of carcinomas of the gallbladder and an atypical carcinoid is thought to be an intermediated type between carcinoid tumor and small cell carcinoma. Dense core "neurosecretory" granules can be found in the above mentioned tumors. We experienced a case of a double tumor of the gallbladder in a 51-year old male patient. Grossly, a large solid mass, about 5.0 cm in diameter, was found in the fundic portion and the neck portion also had a small 1.5 cm-sized polypoid mass. Microscopically, these lesions had features of pleomorphic carcinoma and atypical carcinoid, respectively. Immunohistochemically, they manifested reactivity for neuron specific enolase. Ultrastructural study revealed neurosecretory granules in the cytoplasms of tumor cells of the fundic and neck masses. Although light microscopic features of these tumor masses are quite different, we consider that these tumors represent a spectrum of neuroendocrine differentiation.
Male
;
Humans
9.Atypical Mesoblastic Nephroma: Report of a case.
Jin Man KIM ; Dong Wook KANG ; Seung Ki MIN ; Kwang Sun SUH ; Dae Young KANG
Korean Journal of Pathology 1991;25(6):601-606
Congenital mesoblastic nephroma(CMN) is an important differential diagnosis of a renal mass occurring in the newborn or in early childhood. It was first described by Bolande as a separate disease entity distinct form Wilms' tumor. In 1974, Beckwith has predicted that this tumor has a pathologic spectrum with classic congenital mesoblastic nephroma at one extreme, unequivocally mallignant spindle cell sarcomas at the other, and intermediate "gray zone" lesions of indeterminate biologic significanse. In 1986, Joshi has described "atypical mesoblastic nephroma" as a potentially aggressive variant of CMN, which shows atypical gross and microscopic features such as hemorrhage, necrosis, high cellularity, and mitotic index. We report of a case of atypical mesoblastic nephroma presenting in a 38 days-old male infant. Grossly, the tumor involved the upper and midportion of the left kidney. On section, the cut surface was fleshy, grayish-white, and homogeneous. Microscopically, the tumorshowed high degree of cellularity and arrangement of fusiform cells in sheets and vague interlacing bundles. The individual tumor cells showed fusiform to oval nuclei, indistinct scanty pale-eosinophilic cytoplasm and many mitotic figures.
Infant
;
Child
;
Male
;
Female
;
Infant, Newborn
;
Humans
;
Diagnosis, Differential
10.The clinical value of the ultrasonography in the diagnosis of the malignant ovarian ca.
Kwang Hwi PARK ; Sun Kyung LEE ; Byung Hee SUH ; Jae Hyun LEE ; Jung Eun MOK
Korean Journal of Obstetrics and Gynecology 1993;36(4):543-552
No abstract available.
Diagnosis*
;
Ultrasonography*