1.A case of Sacrococcygeal Teratoma.
Seung Jae YANG ; Kwang Nam KIM ; In Joon SEOL ; Soo Jee MOON ; Keun Soo LEE
Journal of the Korean Pediatric Society 1986;29(5):100-105
No abstract available.
Teratoma*
2.Primary Adenocarcinoma of the Bladder Treated by Pelvic Exenteration : Report of A Case.
Keun WHANG ; Sang Kook YANG ; Kwang Jin KIM ; Kwang Soo YOON ; Hoguen KIM
Korean Journal of Urology 1990;31(4):620-624
Adenocarcinoma of the bladder is a rare tumor. It's incidence figures in the ranges of 0.5 to 2.0 percent of all epithelial bladder neoplasms. Adenocarcinoma of the bladder occurs more frequently in areas which schistosomiasis is endemic and is the most common malignant tumor arising in the exstrophic bladder or urachus. Primary adenocarcinoma of the bladder must be carefully differentiated from the adenocarcinomas that originate within the urachus, prostate, seminal vesicle, breast, gastrointestinal tract or other organs. This report describes a 43 years old male who was diagnosed as an infiltrative adenocarcinoma of the bladder by the preoperative evaluation and transurethral resection of bladder and was confirmed by the pathologic examination following pelvic exenteration as the primary adenocarcinoma or the bladder extended to the prostate and rectum and was followed by chemotherapy without evidence of metastasis.
Adenocarcinoma*
;
Adult
;
Breast
;
Drug Therapy
;
Gastrointestinal Tract
;
Humans
;
Incidence
;
Male
;
Neoplasm Metastasis
;
Pelvic Exenteration*
;
Prostate
;
Rectum
;
Schistosomiasis
;
Seminal Vesicles
;
Urachus
;
Urinary Bladder Neoplasms
;
Urinary Bladder*
3.Correlation Between Tumor Microvessel Density and Prognosis in Breast Cancer.
Kwang Soo YANG ; Kwang Man LEE ; Kwon Mook CHAE ; Hyung Bae MOON
Journal of the Korean Surgical Society 1998;54(4):474-481
It has been recognized that angiogenesis has a profound effect on growth of tumors in various animal models. Recently, it was suggested that tumor microvessel density may be an independent prognostic factor in breast cancer and other human tumors. This study was designed to define the correlation between tumor microvessel density and survival in breast cancer. Pathological parameters of 60 patients with breast cancer were analyzed: stage, nodal status, histologic grade, vascular invasion, and p53 expression. Tumor microvessels were stained by the immunohistochemical method in formalin-fixed, paraffin-embedded tissues by using the anti-CD31 monoclonal antibody (JC/70A, DAKO) and were counted with in a 10 objective field (about 0.74 mm2) in the area of the most intense neovascularization. The microvessel density (MVD) of the tumor was compared with other prognostic factors and 5-year survival rate. The mean MVD of the 60 breast cancers was 36.5 15.3 (range: 17~112). The MVD did not correlate with the stage, the node metastasis, the histologic grade, the vascular invasion, or the p53 expression. The MVD was graded by the number of microvessels as grade 1 (MVD 17~32), grade 2 (MVD 33~48), and grade 3 (MVD>49). The 5-year survival rate of patients with MVD grade 1 was 69.0%, and those of grades 2 and 3 were 58.2% and 29.6%, respectively, which was statistically significant (p=0.004). By univariate analysis, the stage (p<0.001), the axillary nodal status (p<0.001), the MVD (p=0.004), and the p53 expression (p=0.041) had a significant correlation with survival. In 25 patients with node-negative breast cancer, the MVD was the single significant prognostic factor (p=0.047). These results suggest that tumor microvessel density is a significant prognostic factor in invasive breast cancer and that it may be a prognostic factor in node-negative breast cancer.
Breast Neoplasms*
;
Breast*
;
Humans
;
Microvessels*
;
Models, Animal
;
Neoplasm Metastasis
;
Prognosis*
;
Survival Rate
4.Prevalence of antibodies against hepatitis viruses(HAV, HBV and HCV) and seroconversions of HBsAb and HBsAg in vaccinees.
Soo Kwang LEE ; Chul Soon CHOI ; Sang In CHUNG ; Yong Tae YANG
Journal of the Korean Society of Virology 1991;21(2):151-161
No abstract available.
Antibodies*
;
Hepatitis B Surface Antigens*
;
Hepatitis*
;
Prevalence*
5.Effects of Estrogen Deprivation on the Rabbit Clitoral Cavernosal Fibrosis.
Kwang Sung PARK ; Soo Bang RYU ; Yang Il PARK ; Kyu Youn AHN
Korean Journal of Urology 2000;41(7):885-891
No abstract available.
Estrogens*
;
Fibrosis*
6.The Study of the Effect on s-GOT, s-GPT after the Enflurane Auesthesia.
Gap Soo KWON ; In Sook YANG ; In Ho HA
Korean Journal of Anesthesiology 1984;17(4):255-262
In order to observe the effect on liver function after exposure to enlurane which has relatively minimal hepatotoxic effect, we evaluated the changes of the s-GOT & s-GPT levels caused by general anesthesia with enflurane. This study was undertaken to evaluate the effect of enflurane on liver function by comparing the preoperative and postoperative(1st day, 3rd day, 5th day, and 7th day) liver function(s-GOT & s-GPT) tests is il cases of the first general anesthesia with enflurane and 15 cases of a second general anesthesia with enflurane. The results were as folllows: 1) The 1st operative group. a. There are 5 cases (45%) of significant changes of s-GOT levels and no case of significant change in sGPT levels. b. In most of cases, the level of s-GOT & s-GPT have returned to normal values on the 7th postoperative day. 2) The 2nd operative group. a. The increase in the levels of s-GOT was found in 10 cases, and the s-GPT in 6 cases. b. Postoperatively, the simultaneous increase in the levels of s-GOT & s-GPT were found in 4 cases. c. On the 7th postoperative day, the levels of s-GOT & s-GPT was not normal in 3 cases, and not normal for s-GPT in 2 cases. The above results show that the higher of levels of s-GOT & s-GPT after the second general anesthesia with enflurane apparent compared to the levels after the first general anesthesia with enflurane. And it can be assumed that the extreme precaution is necessary in conduction the second general anesthesia with enflurane.
Alanine Transaminase
;
Anesthesia, General
;
Enflurane*
;
Liver
;
Reference Values
7.Effect of Favorite Music Therapy on Stress Response in Patients Undergoing Hysterectomy
Journal of Korean Clinical Nursing Research 2017;23(1):30-39
PURPOSE: The aim of this study was to evaluate the effects of favorite music therapy on the stress response of hysterectomy patients undergoing general anesthesia. METHODS: Date were collected from June 29, 2015 to January 18, 2016 and the participants were 79 hysterectomy patients (experimental group 40 and control group 39). The experimental group listened to their favorite music through earphones from the moment they entered the surgical waiting room until they exited from the post anesthesia care unit. RESULTS: There were statistically significant differences in anxiety (F=15.92, p < .001), systolic blood pressure (F=4.23, p=.008), diastolic blood pressure (F=3.07, p=.033), and heart rate (F=19.93, p < .001) between participants in the experimental group and the control group according to measurement times. CONCLUSION: The study results show that favorite music therapy considering patients' preferences is effective in reducing anxiety among patients undergoing a hysterectomy under general anesthesia, thus leading to a stable change in their blood pressure and heart rate.
Anesthesia
;
Anesthesia, General
;
Anxiety
;
Blood Pressure
;
Heart Rate
;
Humans
;
Hysterectomy
;
Music Therapy
;
Music
8.Gaucher's Disease: A Report of Two Cases in Homozygous Twins
Jae Do KANG ; Kwang Yul KIM ; Yang Hun LEE ; Keun Soo LEE
The Journal of the Korean Orthopaedic Association 1990;25(3):967-972
Gaucher's disease is an uncommon metabolic disorder, which was first described by Gaucher in 1882, characterized by accumulation of distinctive Gaucher's cells in the reticuloendothelial system such as spleen, liver, and bone marrow. The great majority of cases have been reported in Jews, and others in negros and orientals. We are presenting two cases in homozygous twins in Korea, whose clinical manifestations are hepatosplenomegaly and bone lesions due to expansion of involved bones.
African Continental Ancestry Group
;
Bone Marrow
;
Gaucher Disease
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Humans
;
Jews
;
Korea
;
Liver
;
Mononuclear Phagocyte System
;
Spleen
;
Twins
9.An Autopsy Case of Pick's Disease.
Kwang Soo LEE ; Dong Suk SHIM ; Seong Min PARK ; Yeon Soo LEE ; Ki Hwa YANG
Journal of the Korean Neurological Association 2000;18(6):786-789
Pick's disease is a rare neurodegenerative disorder presenting cortical type of dementia. Pick's disease shows unique clinical and pathological features, that are due to a degeneration of fronto-temporal lobes of the cerebrum. The authors experienced a case of Pick's disease in a 58-year-old male patient who had dementia symptoms for five years. The patient showed compulsive behavior since five years ago. Memory decline started from four years ago and progressed. Brain CT disclosed lobar atrophy of the cerebral gyri in frontal and temporal lobes. He died of septicemia associated with aspiration pneumonia. At autopsy, both cerebral hemispheres showed marked encephalomalacia. The gyral atrophy was moderately severe in prefrontal and anterior temporal lobes. Coronal section disclosed moderate dilatation of the lateral ventricles. Microscopically, there were marked neuronal loss in prefrontal and anterior temporal cortices. Also noted were Pick's cells and Pick's body in occasional pyramidal cells preserved.
Atrophy
;
Autopsy*
;
Brain
;
Cerebrum
;
Compulsive Behavior
;
Dementia
;
Dilatation
;
Encephalomalacia
;
Humans
;
Lateral Ventricles
;
Male
;
Memory
;
Middle Aged
;
Neurodegenerative Diseases
;
Neurons
;
Pick Disease of the Brain*
;
Pneumonia, Aspiration
;
Pyramidal Cells
;
Sepsis
;
Temporal Lobe
10.In-vitro culture and characterization of the shed endometrial tissues obtained from menstrual fluid.
Jin Hyun JUN ; Mi Kyoung KOONG ; Inn Soo KANG ; Kwang Moon YANG ; Soo Jeong HONG ; Moon Kyoo KIM
Korean Journal of Obstetrics and Gynecology 2000;43(1):82-86
OBJECTIVE: To evaluate the viability and the characteristics of shed endometrial tissues obtained from menstrual fluid during in-vitro culture. METHODS: The menstrual fluids were collected using Wallace catheter from uterine cavity in 10 women with regular menstruation. The menstrual fluids were washed twice, and the pellets, containing blood cells and shed endometrium, were collected and diluted fivefold with Ham's F-10 medium containing 10% fetal bovine serum. The cell suspension was placed on culture dishes, and cultured for 7 days in an incubator. To evaluate the characteristics of the cultured endometrial cells, immunohistochemical (IHC) staining was performed using anti-cytokeratin and anti-vimentin antibody. RESULTS: The mean volume of menstrual fluids and pellets were 0.7ml and 0.3ml, respectively. Only 15% of the shed endometrial tissues were attached and proliferated in culture dishes, which was considered to have viability. Initially, endometrial epithelial cells and fibroblasts were attached and proliferated, and the area of these cells was increased according to prolong the culture time. Stromal cell colonys were located and proliferated on the epithelial cells. IHC staining showed strongly positive for cytokeratin in epithelial cells and for vimentin in stromal cells. In the confocal microscopic observation of 3-dimensional structure of cultured endometrium, cytokeratin-positive cells (epithelial cells) were located in the pheriphery and cytokeratin-negative cells (stromal cells) inside of the structure. CONCLUSION: From our study, shed endometrial tissues in menstrual fluid showed meaningful viability and closed relationship between epithelial cells and stromal cells during in-vitro culture. Thus, we suggest that the in-vitro culture system of shed endometrium is a suitable model for researches of endometriosis.
Blood Cells
;
Catheters
;
Endometriosis
;
Endometrium
;
Epithelial Cells
;
Female
;
Fibroblasts
;
Humans
;
Incubators
;
Keratins
;
Menstruation
;
Stromal Cells
;
Vimentin