A statistical study was done on 2205 skin tumors filed at Department of Clinical Pathology, Han Kang and Kang Nam Sacred Heart Hospital during last 10 years from 1980 to 1989. The results were summarized as follows : 1. The number of skin tumor surveyed was 2205 among total 67931 biopsy specimens, 2052 benign skin tumors, 153 malignant tumors. 2. The specimens were requested from the Department of Surgery(707 cases, 32.1 %), Dermatology(618 cases, 28.0%), Plastic Surgery(354 cases, 15.79o), and Or thopedic Surgery(223 cases, 10.1% ). 3. Among 2052 benign skin tumors, the frequently observed tumors were epidermal cyst(577 cases, 28.1%), lipoma(398 cases, 19.4%), melanocytic nevus(121 cases, 5.9 %), dermatofibroma(74 cases, 3.6%), cavernous hemangioma(72 cases, 3.5%), ea.ch of pilmatricoma and neurofibroma(63 cases, 3.1% ), granuloma pyogenicum(57 cases, 2.8%), neurilemmoma(53 cases, 2.6%), seborrheic keratosis(45 cases, 2.2%), soft fibroma(45 cases, 2.2%). 4. Among 153 malignant tumors, the frequently observed tumors were squamaus cell carcinoma(50 cases, 32.7%), basal cell carcinoma(45 cases, 29.4%), malignant melanoma(8 cases, 5.2%), Bowens disease(7 cases, 4.6%), metastatic skin tumors(7 cases, 4.6%) in order. Male to female ratio of malignant tumors was 1.6:1 and the peak age incidence was in 6th decade. 5. Male to female ratio of squamous cell carcinoma was 3.2:1 and of basal cell carcinoma 1: 1.3. The peak age incidences of both squamous cell carcinoma and basal cell carcinoma were 6th decade. The predilection sites of squmous cell carcinoma were face, neck and genitalia and those of basal cell carcinoma were face, lower extremities, neck and trunk.
Biopsy ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Female ; Genitalia ; Granuloma ; Heart ; Humans ; Incidence ; Lower Extremity ; Male ; Neck ; Pathology, Clinical ; Skin* ; Statistics as Topic

No abstract available.

Nickel is widely known throughout the world as a common source of contact dermatitis. Korea is one of the rapidly developing countries where the use of nickel and nickel by-products is on the rise. Lacking in ore, Korea imports most of its nickel. In the last ten years, in relation to rapid industrial development, the amount of nickel imported has increased over 1, 000 times. Nickel dermatitis is becoming an increasing problem in the patch test clinic. With regards to this, we have tried the dimethylglyoxime spot test to all materials mentioned in the textbooks which are regarded as nickel sources in other industrialized societies, so as to make an up-to-date list of nickel sources applicable to Korea. In addition, we have also included traditional nickel sources such as acupuncture needles, fire pot, old and new coins and chest of drawers etc. We also have analyzed data concerning nickel imports to Korea during the past 10 years.
Acupuncture ; Dermatitis ; Dermatitis, Contact ; Developing Countries ; Fires ; Korea* ; Needles ; Nickel* ; Numismatics ; Patch Tests ; Thorax

We describe a case of cutaneous angiomyolipoma found in the ear lobe, that is not associated with tuberous sclerosis. The lesion developed on the youngest patient yet reported in the literature.
Angiomyolipoma* ; Ear ; Humans ; Tuberous Sclerosis

Tuberculosis, once thought to be the most common cause of uveal is now thought to be a relatively rare cause of ocular disease. This is because of a decreased incidence of tuberculosis as well as a lessened emphasis on its diagnosis. Tuberculosis of uveal tract has long been a controversial subject in ophthalmology. Several factors have been implicated including the marked pleomorphism of the lesions, owing to variations in the virulence of the invading organisms, host resistance, and the presence or absence of host immunity. Solitary choroidal tuberculoma is rare and characterized as gradually growing until it resembles a tumor projecting as a round white or yellowish globular mass into the cavity of the eye. It may progress continuously and so finally, in the absence of treatment, the sclera is involved and perforation results which is followed by phthisis bulbi or pyogenic infection and panophthalmitis. We have experienced a 19-year old female who had a solitary choroidal tumor like lesion, which about 17 months later resulted in scleral perforation, in the posterior pole of the left eye. We performed enucleation of the left eyeball under the clinical diagnosis of the maligant melanoma associated with scleral perforation and obtained the histopathological diagnosis of ocular tuberculosis.
Choroid ; Diagnosis ; Female ; Humans ; Incidence ; Melanoma ; Ophthalmology ; Panophthalmitis ; Sclera ; Tuberculoma ; Tuberculosis ; Tuberculosis, Ocular ; Virulence ; Young Adult

BACKGROUND: Lichen planus is a papulosquarnous disease characterized by pruritic violaceous papules most commonly an the extremities of middle-aged adults. It may or may not be accompanied by oral and genital mucous membrane involvement. Its course is generally self-limited for a period of several months to years, but it may last indefinitely. OBJECTIVE: This study was performed to find the clinical characteristics of lichen planus. METHODS: Thirty-five cases of lichen planus comfirrned clinically and histopathologically were analyzed. RESULTS: The incidenc of lichen planus was 0.073% of the total number of dermatologic patients. The age distribution was in the range of 14-63 years old being most prevalent in the 6th decade and there was ariequal sex ratio. The most common site of involvement was the mucous membrane, and the extremities were more common than the trunk. Pruitus or pain and discomfort developed in 28 pat,ients(80% ). In most cases, the treatment was topical corticosteroid and antihistamine. Sixteen cses improved within 1 month to 2 years. Five cases recurred in the improved cases. CONCLUSION: The clinical analysis of 35 patients with lichen planus was performed. The incidence of lichen planus was 0.073% of the total number of dermatologic patients. Males and females were equally affected Mucous membrane involvement was detected in 21 patients(60%).
Adult ; Age Distribution ; Extremities ; Female ; Humans ; Incidence ; Lichen Planus* ; Lichens* ; Male ; Mucous Membrane ; Sex Ratio

We reviewed 37 skin biopsies obtained from 35 patients with secondary syphilis during the period of 9 years from January 1980 to June 1988, which had been diagnosed by dark field examination, serologic tests for syphilis, and identification of spirochetes by immunoperoxidase method (avidin-biotin complex) in the skin biopsies. We investigated the histologic features of the skin lesions in secondary syphilis according to the types and patterns of inflammatory cell infiltration in the dermis, vascular reactions and epidermal changes. We matched these histologic findings with the clinical features of the skin lesions. The results were as follows; 1) The histologic patterns of dermal infiltrate in order of frequency were as follows; junctional pattern in 14 biopsies (38%), lichenoid pattern in 10 biopsies (27%), diffuse pattern in 5 biopsies (14%), patchy pattern in 3 biopsies (8%), normal pattern in 3 biopsies (8%) and undertermined in 2 biopsies (5%). 2) The dermal infiltration of plasma cells was found in 24 biopsies (65%). All the biopsies of diffues and lichenoid patterns, 7 biopsies of junctional and one biopsy of patchy pattern showed plasma cells but none in normal pattern. 3) Eosinophils were observed in the dermis in 11 biopsies (30%). There was no difference in incidence of eosinophils in the dermis among morphologic patterns. However, they were frequently seen in the dermis and epidermis of condyloma lata (4 of 7 biopsies). 4) The vascular changes in the dermis included endothelial cell swelling in 23 biopsies (62%), endothelial cell proliferation in 22 biopsies (60%) and vascular dilatation in 10 biopsies (27%). They were most commonly observed in the lichenoid pattern followed by diffuse and junctional patterns. Three cases showed lymphocytic vasculitis. 5) Epidermal changes were seen in all of the biopsies exocytosis, parakeratosis, hydropic change of basal cells, acanthosis, spongiosis, keratinocyte necrosis and hyperkeratosis in the order of frequency. 6) In relation to the clinical manifestations, junctional pattern (14 biopsies) consisted of 6 papulosquamous lesions, 5 macules and 3 papules. Lichenoid pattern (10 biopsies) consisted of 7 papulosquamous lesions and 3 papules. All the biopsies showing diffuse pattern (5 biopsies) appeared in condyloma lata. Patchy pattern (3 biopsies) consisted of 2 macules and 1 papule. All of the normal pattern (3 biopsies) appeared in macules. In conclusion, with dermal and epidermal changes, the acknowlegement of the 5 basic histologic patterns in secondary syphilis seems to be very helpful for the diagnosis of syphilis.
Incidence ; Biopsy

Isolated rupture of the posterior capsule caused by blunt ocular trauma is rarely reported and is usually detected incidentally during surgery for the associated cataract. We report a case of isolated posterior capsule rupture detected during cataract surgery in a 33-year-old man who had traumatic cataract. In this case, the ruptured posterior capsule had relatively large defect in size(5x5 mm)with thickened and fibrosed edge and vitreous opacity existed. The surgical management of this case consisted of phacoemulsification with PC-IOL implantation and pars plana vitrectomy. During surgery, although the posterior capsule rupture was large, further rupture of the capsule was prevented by the fibrosed edge which tightened the margin ofthe ruptured capsule, and so PC-IOL implantation could be possible securely.
Adult ; Cataract ; Humans ; Phacoemulsification ; Rupture* ; Vitrectomy

No abstract available.
Nephrotic Syndrome*

From Oct. 1985 to Mar. 1987, 141 cases of intraocuiar lenses were implanted, and 121 cases had been followed up for more than 2 months. The results were as follows: 1. Surgical technique is planned extracapsular cataract extraction(ECCE) in 81 eyes, Kelman phacoemulsification(KPE) in 21 eyes, Irrigation and Aspiration in 12 eyes, secondary implant in 4 eyes. 2. Post operative visual acuity of 0.5 or better was achieved in 112 eyes(92.5%) and or better in 75 eyes(61.9%). Average of visual acuity was 0.90 +/- 0.25 in toto, 0.88 +/- 0.24 in planned ECCE, 0.96 +/- 0.22 in KPE, 0.92 +/- 0.24 in others. There was not significant carrelation between planned EOCE and KPE(p<0.005). 3. The mean spherical equivalent of post operative corrective spectacle lens power was -0.59 +/- 1.13 in toto, -0.57 +/- 0.92 in planned ECCE. -0.85 +/- 1.13 in KPE. 4. Post operative repractive state was myopic in 98 eyes(80%), emetropic in 10 eyes(8%) and hyperopic in 9 eyes(7%).
Cataract ; Lens Implantation, Intraocular* ; Lenses, Intraocular* ; Visual Acuity