A statistical study was done on 2205 skin tumors filed at Department of Clinical Pathology, Han Kang and Kang Nam Sacred Heart Hospital during last 10 years from 1980 to 1989. The results were summarized as follows : 1. The number of skin tumor surveyed was 2205 among total 67931 biopsy specimens, 2052 benign skin tumors, 153 malignant tumors. 2. The specimens were requested from the Department of Surgery(707 cases, 32.1 %), Dermatology(618 cases, 28.0%), Plastic Surgery(354 cases, 15.79o), and Or thopedic Surgery(223 cases, 10.1% ). 3. Among 2052 benign skin tumors, the frequently observed tumors were epidermal cyst(577 cases, 28.1%), lipoma(398 cases, 19.4%), melanocytic nevus(121 cases, 5.9 %), dermatofibroma(74 cases, 3.6%), cavernous hemangioma(72 cases, 3.5%), ea.ch of pilmatricoma and neurofibroma(63 cases, 3.1% ), granuloma pyogenicum(57 cases, 2.8%), neurilemmoma(53 cases, 2.6%), seborrheic keratosis(45 cases, 2.2%), soft fibroma(45 cases, 2.2%). 4. Among 153 malignant tumors, the frequently observed tumors were squamaus cell carcinoma(50 cases, 32.7%), basal cell carcinoma(45 cases, 29.4%), malignant melanoma(8 cases, 5.2%), Bowens disease(7 cases, 4.6%), metastatic skin tumors(7 cases, 4.6%) in order. Male to female ratio of malignant tumors was 1.6:1 and the peak age incidence was in 6th decade. 5. Male to female ratio of squamous cell carcinoma was 3.2:1 and of basal cell carcinoma 1: 1.3. The peak age incidences of both squamous cell carcinoma and basal cell carcinoma were 6th decade. The predilection sites of squmous cell carcinoma were face, neck and genitalia and those of basal cell carcinoma were face, lower extremities, neck and trunk.
Biopsy ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Female ; Genitalia ; Granuloma ; Heart ; Humans ; Incidence ; Lower Extremity ; Male ; Neck ; Pathology, Clinical ; Skin* ; Statistics as Topic

No abstract available.

Nickel is widely known throughout the world as a common source of contact dermatitis. Korea is one of the rapidly developing countries where the use of nickel and nickel by-products is on the rise. Lacking in ore, Korea imports most of its nickel. In the last ten years, in relation to rapid industrial development, the amount of nickel imported has increased over 1, 000 times. Nickel dermatitis is becoming an increasing problem in the patch test clinic. With regards to this, we have tried the dimethylglyoxime spot test to all materials mentioned in the textbooks which are regarded as nickel sources in other industrialized societies, so as to make an up-to-date list of nickel sources applicable to Korea. In addition, we have also included traditional nickel sources such as acupuncture needles, fire pot, old and new coins and chest of drawers etc. We also have analyzed data concerning nickel imports to Korea during the past 10 years.
Acupuncture ; Dermatitis ; Dermatitis, Contact ; Developing Countries ; Fires ; Korea* ; Needles ; Nickel* ; Numismatics ; Patch Tests ; Thorax

No abstract available.
Nephrosis, Lipoid*

We describe a case of cutaneous angiomyolipoma found in the ear lobe, that is not associated with tuberous sclerosis. The lesion developed on the youngest patient yet reported in the literature.
Angiomyolipoma* ; Ear ; Humans ; Tuberous Sclerosis

No abstract available.
Carcinoma, Renal Cell* ; Caveolin 1*

A case of contact dermatitis due to herb onintment is described in a 24 year-old female patient. After topical application of herb ointment, she developed erythematous papules and plaques on the face and neck. Patch test revealed positive reactions to ammoniated mercury, thimerosal, and the herb ointment. Energy-dispersive X-ray microanalysis of the herb ointment showed a striking peak for mercury.
Dermatitis, Contact* ; Electron Probe Microanalysis ; Female ; Humans ; Neck ; Patch Tests ; Strikes, Employee ; Thimerosal ; Young Adult

Daily excretions of sodium, potassium and urea nitrogen and urine volume of normal Korean were reported by several authors. However, it is generally suspected that dietary composition of Koreans improved during last decade. Author have hypothetized that changes of diet composition could modify urine compositions and volume. In order to determine the urine composition and volume in the late 1970`s, sodium and potassium concentrations were measured by flame photometry and urea nitrogen by urease indophenol method in the urine from 50 rural residents. The residents were composed of 10 public officials, 18 male farmers and 22 female farmers. Followings were the results: 1. Daily urine volume Total average : 1594.20+/-443.89 ml/day, Public official : 1714.00+/-548.00 ml/day Male farmer :1508.89+/-310. 54ml/day, Female farmer: 1612.27+/-496.04 ml/day 2. Daily urinary sodium excretion Total average : 5.19+/-1.21 g/day. Public official : 5.62+/-1.93 g/day Male farmer : 4.73+/-1.10 g/day, Female farmer: 5.37+/-0.98 g/day 3. Daily urinary potassium excretion Total average : 1.79+/-0.59 g/day, Public official : 1.97+/-0.60 g/day Male farmer : 1.91+/-0.59 g/day, Female farmer : 1.62+/-0.58 g/day 4. Daily urinary urea nitrogen excretion Total average : 7.26+/-l.95 g/day, Public official : 8.06+/-1.65 g/day Male farmer: 7.53+/-2.40 g/day. Female farmer : 6.67+/-1.65 g/day A comparison of these data with corresponding figures obtained from Western reporters indicate that the concentration and excretion of sodium of rural Koreans are still higher significantly, while those of potassium and urea nitrogen are lower than those of Westerns significantly. On the other hand, a comparison with corresponding figures obtained from other Korean reporters in the 1960's indicate that sodium excretion of present data is lower while potassium and urea nitrogen are higher than those of the 1960's. It is speculated that these peculiarities of urinary composition shown in rural Koreans in the late 1970's are attributed to improved protein ingestion combined with decreased salt intake as compared to 1960's, however, the levels are still far from Westerns.
Diet ; Eating ; Female ; Hand ; Humans ; Indophenol ; Male ; Nitrogen* ; Photometry ; Potassium* ; Sodium* ; Urea* ; Urease

Eosinophilic granuloma of bone well-documented in the literature. This lytic bone disease most commonly occurs in children, but a fraction of the cases does occurs in adult. When the disease occurs in adults, the bone most often affected include the skull, ribs, mandible, clavicle, pelvis, and long bone of the extremities. We report the case of a 31-year old woman with isolated eosinophilic granuloma of the thoracic spine. She had a 1-month history of progressive back pain that radiated to the right anterior chest. Authors performed resection of vertebral body lesion and soft tissue lesion and anterior fusion from T7 to T9. Immunochemical staining showed a positive S100 protein stain. EM demonstrated characteristic Birbeck granule. Postoperatively, the patient underwent a 5-day course of RT to the T6-T10 spine with 200cGY fractions (total dose 1000cGY). Postoperatively, the patient's back and chest pain had disappeared. There is no evidence of local recurrence or distant metastasis at 18 months follow-up. Though rare, eosinophilic granuloma of the adult spine could be considered in the differential diagnosis of osteolytic lesions.
Adult* ; Back Pain ; Bone Diseases ; Chest Pain ; Child ; Clavicle ; Diagnosis, Differential ; Eosinophilic Granuloma* ; Eosinophils* ; Extremities ; Female ; Follow-Up Studies ; Humans ; Mandible ; Neoplasm Metastasis ; Pelvis ; Recurrence ; Ribs ; Skull ; Spine* ; Thorax

BACKGROUND: We investigated the effectiveness of pain management and the adverse events of intravenous (IV) patient-controlled analgesia (PCA) after orthopedic surgery. METHODS: From September 2014 and August 2015, we performed a retrospective analysis of 77 patients who underwent orthopedic surgery of the shoulder or the elbow in our hospital. The composition of the intravenous PCA administered to the patients was as follows: 250 mg of dexketoprofen trametamol, 70 mg of oxycodone, and 0.6 mg of ramosetron, which were made up to 79 ml of normal saline. We evaluated and statistically analyzed the difference in the visual analogue scale (VAS) scores for pain at immediate postoperation, at 24 hours of PCA, at 72 hours of PCA, and after discontinuation of PCA and in the incidence of adverse events. RESULTS: We found that VAS score decreased for 3 postoperative days and that with discontinuation of IV PCA a meaningful change in VAS score was no longer seen. Of the 77 patients, 22 presented with adverse events (28.6%). We terminated IV PCA temporarily in the 21 patients who presented with adverse events; we terminated analgesia permanently in one patient (1.2%). Consequently, 76 of 77 patients carried out IV PCA till the designated period. CONCLUSIONS: Intravenous PCA after orthopedic surgery of the shoulder or the elbow may be accompanied with adverse events. Careful assessment of the patient and treatment of the adverse outcomes are key to a successful maintenance of PCA and to a successful management of postoperative pain.
Analgesia ; Analgesia, Patient-Controlled* ; Anti-Inflammatory Agents, Non-Steroidal ; Elbow* ; Humans ; Incidence ; Orthopedics ; Oxycodone ; Pain Management ; Pain Measurement ; Pain, Postoperative* ; Passive Cutaneous Anaphylaxis ; Retrospective Studies ; Shoulder*