Thumb reconstruction with a free neurovasculsr wrap around flap from the great toe by microsurgery had been first reported by O'Brien, Macleod and Morrison in 1980. We have performed one case of thumb reconstruction with psrtial first metstarsus for loss of thumb except pulp and one digital vessel by microsurgery. The results were summerized as followings ; 1. This one stage procedure has the unique advantage to reconstruct a thumb almost identical to the origin. 2. This technique allows preservstion of the toe and the secondary defect results in no significant morbidity.
Free Tissue Flaps ; Microsurgery ; Thumb ; Toes

Ultraviolet radiation of skin leads to a systemic alteratior tkat inhibits the normal pattern of immunologic tumor rejection., suppresses the contact hypersemisivity and transiently alters the morphology and the surface marker characteristics of Langerhans cells. Moreover, Ultraviolet radiation elaborates the ETAF, neuropeptides, proteins, and urocaicacid which may alter immunologic responses. But no other study about the effects of UVB irradiation on the systemic immunologic functions of the macrophages of internal organs was reported. The macrophages of the reticuloendothelial system (RES) play a central role in cell-mediated immunity, because they are involved both in the initiation of responses as antigen-presenting, cells, and in the effector phase as inflammatory, tumoricidal and microbicidal cells. The present study was intended to investigate the effects of UVB irradiation on the immunologic functions of mouse peritoneal macrophages. Normal 6-8-week-old BALB/c mice were exposed at the dose rate of 20mJ/cm and 40mJ/cm of UVB per day, 5 days per weeks for 2 weeks, 4 weeks and 8 weeks. Then the peritoneal macrophages were obtained from the mice and the changes of cell count, chemotactic index, phagocytic index, NBT reduction rate and superoxide (0) production were examined. The results were as follows : 1)the number of mouse peritoneal macrophages was decreased by UVB radiation, 2) the chemotactic index of mouse peritoneal macrophage was not altered by UVB radiation, 3) phagocytic activity of mouse pertoneal macrophage was significsntly decreased by UBV radiation, 4) NBT reduction rate in mouse aeritoneal macrophage after UVB radiation was sinificanily decreased in all experimental group, and 5) Superoxide (0) production in mouse peritoneal macrophage after UVB radiation was decreased in all experimental groups.
Animals ; Cell Count ; Immunity, Cellular ; Langerhans Cells ; Macrophages ; Macrophages, Peritoneal* ; Mice* ; Mononuclear Phagocyte System ; Neuropeptides ; Skin ; Superoxides

No abstract available.

No abstract available.
Animals ; Cattle*

Synovial chondromatosis is a rare entity characterized by metaplastic cartilage formation within the synovial connective tissue and the shedding of loose bodies into the joint. Of the four cases of synovial chondromatosis, experienced by authors, three involved the knee joint and one the proxiaml phalanx of the left index finger. A huge chondroma was found in the knee joint of 2 years old boy and the other one in the proximal phalanx of the left index of 11 years old girl. Histological findings disclosed the metaplastic transformation of synovium into cartilage in all cases.
Cartilage ; Chondroma ; Chondromatosis, Synovial ; Connective Tissue ; Female ; Fingers ; Humans ; Joints ; Knee Joint ; Male ; Synovial Membrane

No abstract available.
Epidermal Cyst

BACKGROUND: Previous studies have shown that in vitro exposure to ultraviolet B(UVB) radiation resulted in a dose-dependent inhibition of natural killer activity(NK activity) of normal human peripheral blood mononuclear cella(PBMC), and that in vivo exposure to snlight also induced NK activity suppression. The precise meehanism of the UV-regulation on the riat iral killer system(NK system) is not established. Objective & METHOD: The purpose of this study is to examine whether the addition of interleukin-2(IL-2) and/or free oxygen radical scavengers, superoxide dismutas(SOD) or sodium azide(SA), is effective in reducing the UVJ3-induced suppression of NK activity of FBMC. RESULTS: The results are as follows 1. The suppressive effect of UVB radiat,ion on NK activity could successfully be prevented in the presence of SOD(100 and 1,000U/ml) during the radiation. 2. SA( LO and 10 M/ml) did not prevent the suppression of NK activity. 3. IL-2(100U/ml) markedly enhanced the NK activity of nonirradiated PBMC, but had no effect on irradiated PBMC. 4. Combination treatment with both IL-2 and free radical scavengers on UVB-irradiated PBMC resulted in no additive or synergistic effect on the prevention of the suppression of NK activity compared with a single treatment with either IL-2 or free radical scavengers. CONCLUSION: In the presserit study, we found that SOD providec a protective effect on NK activity during the UVB radiation and we suggest that superoxide anion(O ) might play a major role in the UV-regulatory mechanisms of the NK system.
Free Radical Scavengers ; Humans* ; Interleukin-2* ; Oxygen ; Sodium ; Superoxides

Comminuted fracture of the acetabulum in association with dislocation of the hip has aiways been a serious injury because of its protracted convalescent period and the permanent disability. Conventional open reduction, however, has contained much technical difficulties and its end result has usually been disappointing to both the patient and the surgeon. Recent concept is that total hip replacemet can be the primary choice of treatment in the management of such complicated injuries. In contemplating THR in this occasion, however, the acetabular defect secondary to its fracture-dislocation stands out as a primary source af cup loosening atter operation. A special consideration has been given in this respect and in five clinical cases the TMR with our modification was carried out with the following results. 1. In three cases of comminuted central fracture-dislocation of the hip, the gap and deformity of the fractured acetabulum was successfully corrected by inserting two pieces of T-shaped bone graft taken from the removed femoral head. 2. In another two cases of comminuted posterior fracture-dislocation of the hip, the posterior wall defect of the acetabulum was prepared by reduction of the fragments displaced and then temporary fixation with two Steinmann pins during the operative step of cup insertion. The pins could easily be removed after setting of the bone cement. 3. By applying this new modification, the THR surgery was successful and uneventful in all five cases with smooth postoperative courses.
Acetabulum ; Arthroplasty, Replacement, Hip ; Congenital Abnormalities ; Dislocations ; Fractures, Comminuted ; Head ; Hip ; Humans ; Transplants

In recent years, the incidence of traumatic dislocation of the hip joint appears to be on the increase, year by year, as the rate of traffic and industrial accidents increases. To prevent complications after dislocation of the hip, many authors have pointed out the importance of the early accurate reduction. But many authors have advocated different methods for aftercare treatment. In this paper, the author has reviewed 34 patients of traumatic disolocation of the hip who had been hospitalized and treated at Hanyang University Hospital from May 1972 to Dec. 1980. It was possible to follow 21 of these patients for an average followup period of 54 months. With this study, the following results were obtained. l. Of 34 patients, 31 patients were male and 3 were female. The prevalent age distribution was from 21 to 30 years of age 12 patients (35.3%) showing this distribution. 2. 30 (88.4%) of 34 dislocations of the hip were the result of traffic accidents, 22 of these being auto accidents. 3. The order of incidence according to the Thompson-Epstein classification is; posterior type I (44.1%), III (23.5%) and type II (11.8%). 4. 28 (82.4%) dislocations of the hip were complicated by multiple injuries at other sites. The most common site of associated injury was the ipsilateral lower extremity, which occurred in 15 patients. 5. 27 closed reductions, 5 open reductions and 1 prosthetic replacement of femoral head were performed, and 24 (88.9%) of 27 closed reductions were performed within 24 hours. 6. By Thompson-Epstein method, the author evaluated 21 patients who could be followed for an average of 54 months, and so obtained excellent or good results in 16 patients (71.4%) and fair or poor results in 5 patients (28.6%). Of these 21 patients, 13 patients who were performed closed reduction with 24 hours were results of excellent of good. 7. As complications avascular necrosis, traumatic arthritis and ectopic ossification developed in one, four and three patients respectively. In addition 5 patients developed sciatic nerve injuries, 3 of these recovered completely.
Accidents, Occupational ; Accidents, Traffic ; Aftercare ; Age Distribution ; Arthritis ; Classification ; Clinical Study ; Dislocations ; Female ; Follow-Up Studies ; Head ; Hip Joint ; Hip ; Humans ; Incidence ; Lower Extremity ; Male ; Methods ; Multiple Trauma ; Necrosis ; Ossification, Heterotopic ; Sciatic Nerve

BACKGROUND: Psoriasis is a disabling and intractable disease influencing the psychosocial life of the patients. Patients who are frustrated with orthodox medicine may explore alternative therapies. OBJECTIVE: This study was done to research on the actual condition of the use of alternative medicine in the patients with psoriasis. METHODS: A self-administered questionnaire was constructed, and was given to the patients to answer our questions. RESULTS: Among 128 patients with psoriasis, 61 (47.7%) reported previous use of one or more forms of alternative medicine. The absence of satisfactory long-term effects of physician-provided therapy was the main reason for patients trying alternative medicine. Persons without skin s disease and the mass media were the main sources of information on alternative medicine. CONCLUSION: Alternative therapies were widely utilized by subjects participating in this study, and dermatologists need to be aware of alternative treatments employed by their patients.
Complementary Therapies* ; Humans ; Mass Media ; Psoriasis* ; Skin