1.Anatomical Sites of the Successful Catheter Ablation Using the Anatomic Approach in Patients with AV Nodal Reentrant Tachycardia.
Kwang Soo SONG ; Sang Min LEE ; Yoon Nyun KIM
Korean Circulation Journal 1999;29(2):174-181
BACKGROUND AND OBJECTIVES: Intracardiac electrocardiographic finding using as a guide for selective catheter ablation in patients with AV nodal reentrant tachycardia (AVNRT) is not specific. Therefore, we evaluated the efficacy and safety of the anatomical approach for catheter ablation in patients with AVNRT. MATERIALS AND METHOD: Among the patients diagnosed as AVNRT by electrophysiologic study, total 66 patients (M:F=26:40) were included in this study. In the right anterior oblique radiographic view, the septal annulus of tricuspid valve, extending from the most posterior region of the annulus adjacent to coronary sinus ostium (posterior) to His bundle recording site (anterior), was divided into posterior (P), mid (M), and anterior (A) sites. Radiofrequency (RF) energies were applied from the posterior part to the anterior part sequentially along the septal annulus of tricuspid valve until successful ablation. RESULTS: Successful anatomical sites were located in posterior (11 patients), mid (48 patients), and anterior (7 patients) sites. The most patients (62 patients) were treated with slow pathway ablation except 4 patients in whom fast pathway was ablated. Probable slow potentials were observed in 8 patients (12%, 3 in posterior sites and 5 in mid sites). Transient complete AV block followed by first degree AV block and delayed complete AV block was occured in one case whose ablation site was A1. And another 3 patients had postablation first degree AV block. CONCLUSION: In patients with AVNRT, the ablated pathway were different according to successful anatomical site. And RF catheter ablation of atrioventricular nodal reentrant circuit guided by anatomical landmark is safe and efficacious.
Atrioventricular Block
;
Bundle of His
;
Catheter Ablation*
;
Catheters*
;
Coronary Sinus
;
Electrocardiography
;
Humans
;
Tachycardia, Atrioventricular Nodal Reentry*
;
Tricuspid Valve
2.Syphilitic Charcot Spine: Report of a Cases
Deuk Soo HWANG ; Kwang Zin LEE ; Seung Ho YUNE ; Jun Kyu LEE ; Ok Nyun KIM
The Journal of the Korean Orthopaedic Association 1984;19(2):417-422
In 1868 Charcot described the joint in tabes dorsalis, which since then has been designated as Charcot neuroarthrophathy. It is characterized by painless swelling and abnormal mobility of the affected joint. Arthrophthy of the type described by Charcot has been associated with various other conditions, such as diabetes mellitus, syringomyelia, injury to nerve root, congenital indifference of pain, leprosy, and intra articular use of steroid, etc. Authors present a case of Charcot spine due to tabes dorsalis.
Diabetes Mellitus
;
Joints
;
Leprosy
;
Spine
;
Syringomyelia
;
Tabes Dorsalis
3.Infantile myofibromatosis.
Kyoung Ho KIM ; Young Nyun PARK ; Hee Jae JOO ; Kwang Gil LEE ; Chanil PARK ; Dong Soo KIM
Yonsei Medical Journal 1989;30(4):376-382
We report a case of infantile myofibromatosis in a male infant with involvement of the lungs and subcutaneous tissue. We studied our case by light microscopy, immunohistochemistry and electron microscopy. The results reveal that this entity is of a myofibroblastic nature. We reviewed 165 cases including our case. We believe this is the first report in Korea of infantile myofibromatosis with pulmonary involvement.
Case Report
;
Human
;
Infant, Newborn
;
Leiomyoma/*pathology/ultrastructure
;
Lung Neoplasms/*pathology/ultrastructure
;
Male
;
Microscopy, Electron/methods
;
Prognosis
;
Skin Neoplasms/*pathology/ultrastructure
4.Infantile myofibromatosis.
Kyoung Ho KIM ; Young Nyun PARK ; Hee Jae JOO ; Kwang Gil LEE ; Chanil PARK ; Dong Soo KIM
Yonsei Medical Journal 1989;30(4):376-382
We report a case of infantile myofibromatosis in a male infant with involvement of the lungs and subcutaneous tissue. We studied our case by light microscopy, immunohistochemistry and electron microscopy. The results reveal that this entity is of a myofibroblastic nature. We reviewed 165 cases including our case. We believe this is the first report in Korea of infantile myofibromatosis with pulmonary involvement.
Case Report
;
Human
;
Infant, Newborn
;
Leiomyoma/*pathology/ultrastructure
;
Lung Neoplasms/*pathology/ultrastructure
;
Male
;
Microscopy, Electron/methods
;
Prognosis
;
Skin Neoplasms/*pathology/ultrastructure
5.New clinical classification according to clinico-biochemical risk factors in the management of untreated persistent gestational trophoblastic tumor.
Jung Il CHA ; Kwang Duck KO ; Seok Nyun BAE ; Jae Kun JUNG ; Chang Yee KIM ; Seung Jo KIM ; Hun Young LEE
Korean Journal of Obstetrics and Gynecology 1991;34(6):828-837
No abstract available.
Classification*
;
Risk Factors*
;
Trophoblastic Neoplasms*
;
Trophoblasts*
6.A Case of Postoperative Recurrence of Hepatocelluar Carcinoma in Pelvic Bone without Intrahepatic Metastasis Eight Year After.
Deok Kyu CHO ; Kwang Hyub HAN ; Jae Youn CHEONG ; Do Yun LEE ; Se Hoon KIM ; Young Nyun PARK
The Korean Journal of Hepatology 2001;7(3):315-319
In hepatocellular carcinoma distant metastasis after curative surgical resection without intrahepatic metastasis is very rare. A 55-year old man presented with a huge pelvic bone mass. Eight years ago he underwent posterior hepatic segmentectomy following diagnosis of hepatocelluar carcinoma. He has received regular check-ups with abdominal ultrasonography and serum alpha-fetoprotein. On admission an MRI on the pelvic area showed an 18x10 cm sized lobulated mass invading the pelvic bone and acetabulum. Microscopic examination revealed that the tumor was a well differentiated hepatocellular carcinoma. There was no evidence of intrahepatic recurrence. He was treated with transarterial chemoembolization, external radiotherapy (total 3750 cGy), and systemic chemotherapy using 5-fluorouracil.
Acetabulum
;
alpha-Fetoproteins
;
Carcinoma, Hepatocellular
;
Diagnosis
;
Drug Therapy
;
Fluorouracil
;
Humans
;
Magnetic Resonance Imaging
;
Mastectomy, Segmental
;
Middle Aged
;
Neoplasm Metastasis*
;
Pelvic Bones*
;
Radiotherapy
;
Recurrence*
;
Ultrasonography
7.Pathological Analysis of 62 Liver Biopsy Cases with Hepatocellular Cholestasis: Drug and Toxin Induced Liver Injury.
Min Sun CHO ; Young Nyun PARK ; Myeong Jin KIM ; Kwang Jo CHAE ; Chanil PARK
Korean Journal of Pathology 2001;35(2):123-128
BACKGROUND: Hepatocellular cholestasis denotes the alteration of bile secretion by hepatocytes. The causes, degree of hepatocyte injury and concomitant bile duct loss are considered to influence the clinical course. METHODS: The causes and pathological features of hepatocellular cholestasis were analyzed in 62 cases of liver biopsies; and the causes of primary biliary cirrhosis, primary sclerosing cholangitis, and biliary obstruction were not included. RESULTS: The mean age of the patients was 42.2 years, and the ratio of male to female was 1.8:1. Fifty-eight cases (94%) showed cholestatic hepatitis, and 4 cases (6%) showed pure cholestasis without hepatitis activity. The majority of the cases (52 cases, 84%), including 19 cases of herbal medicine, was related to drugs. Loss of bile duct was found in 12 cases (19%), which were all cases of chronic cholestasis. All of them had drug histories, including 9 cases of herbal medicine. Clinical follow-up was performed in 9 out of the 12 cases with bile duct loss, and all of them showed elevated total bilirubin and/or alkaline phosphatase levels for more than 6 months. CONCLUSION: Drugs are the major cause of hepatocellular cholestatic hepatitis/cholestasis; and information about drugs, including herbal medicines, should be considered for proper evaluation of liver biopsy with hepatocellular cholestasis. Bile duct loss should be evaluated in the cases of chronic hepatocellular cholestasis, especially in drug induced cases.
Alkaline Phosphatase
;
Bile
;
Bile Ducts
;
Bilirubin
;
Biopsy*
;
Cholangitis, Sclerosing
;
Cholestasis*
;
Female
;
Follow-Up Studies
;
Hepatitis
;
Hepatocytes
;
Herbal Medicine
;
Humans
;
Liver Cirrhosis, Biliary
;
Liver*
;
Male
8.Effect of DA-9701 on the Normal Motility and Clonidine-induced Hypomotility of the Gastric Antrum in Rats.
Je Wook KANG ; Dae Kyeong HAN ; Ock Nyun KIM ; Kwang Jae LEE
Journal of Neurogastroenterology and Motility 2016;22(2):304-309
BACKGROUND/AIMS: DA-9701 is a novel prokinetic agent. In the present study, we investigated the effect of DA-9701 on the motility of the gastric antrum in the normal and clonidine-induced hypomotility in an in vivo animal model. METHODS: A strain gauge force transducer was sutured on the gastric antrum to measure the contractile activity in rats. A total of 28 rats were subclassified into the 4 groups: (1) the placebo group, (2) the DA-9701 group, (3) the placebo group in the clonidine-pretreated rats, and (4) the DA-9701 group in the clonidine-pretreated rats. After the basal recording, either placebo (3% [w/v] hydroxypropylmethyl cellulose) or DA-9701 was administered. Contractile signals were measured after the administration and after a meal. In the clonidine-pretreated rats, either placebo or DA-9701 was administered. Contractile signals were measured after the administration and after a meal. RESULTS: Oral administration of DA-9701 did not significantly alter the motility index of the gastric antrum in the preprandial and postprandial periods, compared with the placebo group. The administration of clonidine decreased the motility index of the gastric antrum in the preprandial and postprandial periods, compared with the administration of placebo. This reduction of the antral motility by the administration of clonidine was not observed in the clonidine-pretreated DA-9701 group. The percentage of the motility index in the postprandial period was significantly greater in the clonidine-pretreated DA-9701 group, compared with the clonidine-pretreated placebo group. CONCLUSIONS: DA-9701 improves the hypomotility of the gastric antrum induced by clonidine, suggesting its gastroprokinetic effect in the pathologic condition.
Administration, Oral
;
Animals
;
Clonidine
;
Meals
;
Models, Animal
;
Postprandial Period
;
Pyloric Antrum*
;
Rats*
;
Transducers
9.Analysis of the Gene Expression by Laser Capture Microdissection (III): Microarray Analysis of the Gene Expression at the Mouse Uterine Luminal Epithelium of the Implantation Sites during Apposition Period1.
Se Jin YOON ; Eun Hyun JEON ; Chang Eun PARK ; Jung Jae KO ; Dong Hee CHOI ; Kwang Yul CHA ; Se Nyun KIM ; Kyung Ah LEE
Korean Journal of Fertility and Sterility 2002;29(4):323-336
No abstract available.
Animals
;
Epithelium*
;
Gene Expression*
;
Laser Capture Microdissection*
;
Mice*
;
Microarray Analysis*
;
Phenobarbital*
10.The Effectiveness of School Based Short-Term Social Skills Training in Children with Attention-Deficit/Hyperactivity Disorder(ADHD).
Myung Jae PAEK ; Jung Kwang AHN ; So Yun LIM ; Yang Ryul KIM ; Min Hyeon PARK ; Boong Nyun KIM ; Soo Churl CHO ; Min Sup SHIN ; Jae Won KIM ; Hyo Won KIM
Journal of the Korean Academy of Child and Adolescent Psychiatry 2009;20(2):82-89
OBJECTIVES: Children with attention-deficit hyperactivity disorder (ADHD) often have difficulties in social behavior. The aim of this study was to evaluate the effectiveness of a short-term training program for improving social skills, selfperception and attention deficits. METHODS: The subjects were nine children diagnosed with ADHD with (or without) other mental disorders using the Diagnostic Interview Schedule for Children (DISC-ADHD) module. Children were given eight sessions of a social skills training program. Parents of children simultaneously participated in their own training which was designed to support their children's generalization of skills. Assessments included child, parent and teacher ratings of social skills, self-perception and attention deficit at baseline and post-treatment. RESULTS: Social skills training led to significant improvements in child-reported measures of self-esteem, in teacherreported measures of social skills, and in parent-reported measures of attention deficit. CONCLUSION: This study suggests that short-term social skills training programs for children with ADHD may improve their social skills, self-perception and attention deficits.
Appointments and Schedules
;
Child
;
Generalization (Psychology)
;
Humans
;
Mental Disorders
;
Parents
;
Self Concept
;
Social Behavior