The ulnar nerve entrapment at the wrist is usually caused by carpal ganglion, occupational neuritis, ulnar artery disease, fractures of the carpal bones, tumors, rheumatioid arthritis, etc. The ganglion is the most common cause of the distal ulnar nerve entrapment. A fort-two years old woman complained of insidious motor weakness of the left hand. The electromyogram revealed distal ulnar nerve palsy. On examination, her sensibility of affected hand was normal; there were no Tinel's sign and palpable mass on the Guyon's canal and palm; there was obvious wasting of all the interossei. On surgical exploration, the deep branch of the ulnar nerve was compressed by a ganglion at the mid-palmar space, not in the Guyon's canal. Four months after removal, the clawing of the 4th and 5th fingers disappeared, and the pinch power of the left hand recovered normally seventeen months later.
Animals ; Arteries ; Arthritis ; Carpal Bones ; Female ; Fingers ; Ganglion Cysts ; Hand ; Hoof and Claw ; Humans ; Paralysis ; Ulnar Nerve Compression Syndromes ; Ulnar Nerve ; Ulnar Neuropathies

During recent 3 years, the authors had treated surgically 31 patients who have had old nerve injuries. 19 patients(21 nerves) of them could be followed for more than 1 year after operation. Of these patients, children were 5 and adults were 14. The elapsed time from the injury were from 3 weeks to 20 months(18 cases under 6months and 3 cases above 6 months). The methods of operation were epineural suture(4 cases), grouped interfascicular suture(8 cases), neurolysis(8cases) and nerve graft(1 case). There were satisfactory or good results in 9 nerves of the 21 old nerve injuries. In 4 of 5 children and 5 of 16 adults, good results were obtained. There were 2, 6 satisfactory or good results in 4 epineural sutures and 8 grouped interfascicular sutures and all poor results in 8 neurolyses. One case treated with nerve graft with sural nerve was showed good result. 9 cases of 18 old injuried nerves under 6 months from injury were good results. All 3 cases over 6 months from injury were poor results.
Adult ; Child ; Humans ; Sural Nerve ; Sutures ; Transplants

Hand injuries in the industries have been steadily increasing in this country in recent years. All structures are damaged when a hand is caught in punch presses, gears or under falling objects. Irreversible loss of blood supply to the part is only real indication for primary amputation. Statistical observations were carried out on 240 patients of hand injuries who were treated at the Deparement of Orthopedic Surgery, College of Medicine, Hanyang University from May, 1972 to April, 1977 and following results were obtained. 1. The peak incidence was in the age group from 11 to 20 years in 83 cases(38.4%) and of the 226 patients, 204(85.0%) were male and 36(15.0%) were female. 2. In general, the incidence of hand injuries per year was annually increased and was much more occurred on April than other months of year. 3. The injured ratio of both hands was almost equal and main causes of hand injury were industrial accident (72.1%), traffic accident(12.9%) and electric accident(6.3%). 4 Most of hand injured patients(81.7%) arrived at our hospital within 6 hours after accidents 5. Of 240 injuries, 78(32.5%) were crushing injury with open comminuted fracture, 39(16.2%) were open fracture and 30(12.5%) were closed fracture. 6. Of injured fingers, 126(51.2%) were mondigit and the remained were polydigits. 7. The most frequency of monodigit injury was index finger(32.5%) and of polydigits injury was middle finger(28.2%) 8. In mondigit amputation, index finger were generally amputated at metacarpo-phalangeal joint and middle finger at proximal phalangeal level. 9. Of 457 injuries with facture, 213(46.6%) were treated by debridement and primary suture, and 94 (20.6%) by debridement and open reduction with Kirschner wire fixation. 10. Of 240 patients, 46 cases(19.2%) were infected and the main causative organisms were pseudomonas aeruginosa (41.3%), Staphylococcus aureus(17.3%) and Alkaligenus fecalis(10.9%).
Accidental Falls ; Accidents, Occupational ; Amputation ; Clinical Study ; Debridement ; Female ; Fingers ; Fractures, Closed ; Fractures, Comminuted ; Fractures, Open ; Hand Injuries ; Hand ; Humans ; Incidence ; Joints ; Male ; Orthopedics ; Pseudomonas aeruginosa ; Staphylococcus ; Sutures

Ex.traosseous osteogenic sarcoma is exceedingly rare although bone formation occurs commonly in different reactive processes or neoplasms. Most of this tumors occurred in the lower extremities of middle aged people. The overall prognosis is grave and local recurrence following simple local excision possibly contributes to the poor prognosis. An agressive surgical approach including major amputation is recommended as the primary form of treatment. We have experienced a case of extraosseous osteogenic sarcoma of left gluteal region at the site of therapeutic irradiation for cervical carcinoma 16 years previously.
Amputation ; Buttocks ; Humans ; Lower Extremity ; Middle Aged ; Osteogenesis ; Osteosarcoma ; Prognosis ; Recurrence

A clinical study was made on 148 cases of cutaneous malignant tumors that visited the Department of Dermatology at Seoul National University Hospital during a 11-year period from 1973 to 1983. The results were summarized as follows: 1) The incidence of cutaneous malignant tumors in the total number of outpatients visiting the Department of Derrnatology was 0. 025g. 2) There were 90 cases of male (60. 8p,) and 58 cases of female (39. 2g). The ratio of male to female was l. 55: l. Among the 148 cases of cutaneous malignant tumors, the most frequently observed type was basal cell carcinoma, 58 cases (3j.2 p:). The next most frequent types were squamous cell carcinoma, 42 cases(28. 4g) and malignant melanoma, ]1 cases (7. 4g). We described the clinical characteristics of the patients with basal cell carcinoma, squamous cell carcinoma and malignant melanoma that have been observed.
Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Dermatology ; Female ; Humans ; Incidence ; Male ; Melanoma ; Outpatients ; Seoul

No abstract available.
Biopsy, Fine-Needle* ; Breast*

No abstract available.
Knee*

BACKGROUND: The immortalized human keratinocyte line, HaCaT cells have been widely used as substitutes for normal epidermal keratinocytes. Recently, reconstruction of a skin equivalent using HaCaT cells showed a multilayered epithelium,but somewhat different tissue architecture as compared with normal epidermis. OBJECTIVE: In this study, using HaCaT cells we tried to reconstruct an epidermis resembling more closely to normal epidermis than the previous results. MATERIALS AND METHODS: HaCaT cells were cultured in air-liquid interface on a recently developed dermal substrated in our laboratory, de-epidermized dermis (DED) raised on fibroblast-populated collagen matrix and the result was compared with those on DED or fibroblast-populated collagen matrix alone. RESULTS: HaCaT cells on the new dermal substrate formed a multilayered epithelium with rete ridges, showing rather orderly cellular organization compared with those on fibroblast-populated collagen matrix. However, horny and granular layers were not observed contrary to normal epidermis. Immunohistochemical studies revealed that differentiation markers such as keratin 1, keratin 6 and involucrin showed the similar pattern to those in HaCaT cells cultured on fibroblast-populated collagen matrix. Markers of terminal differentiation, loricrin and filaggrin were not expressed contrary to normal epidermis. CONCLUSION: These results suggest that organotypic culture HaCaT cells on the dermal substrate combines DED with fivroblast-populated collagen matrix results in incomplete differentiation of HaCaT cells contrary to normal keratinocytes.
Antigens, Differentiation ; Collagen* ; Dermis* ; Epidermis ; Epithelium ; Humans ; Keratin-1 ; Keratin-6 ; Keratinocytes ; Skin

Only several stages of conventional operation have been able to treat the open fracture of the limb with extensive bone and soft tissue loss. So we, authors, reviewed 25 cases of vascularized osteocutaneous fibulat transfer which were performed to the extensive bone defect of the limb and associated soft tissue injury(from May 13, 1982 to September 30, 1988). In 25 cases, one case was a chronic osteomyelitis combined pseudocarcinomatous epithelial hyperplasia of surrounding soft tissue, the other(24 cases) were the open comminuted fractures with the extensive bone and soft tissue loss of the limbs. The average size of the skin flap was 12.33 × 5.83cm, the average length of vascularized fibula was 16.5cm in length. The complications were fractures of grafted fibula, partial necrosis of both ends of the skin flap and uncontrolled infection of proximal end of grafted fibula. During postoperative period, the patency of the anastomoses were monitored by observing the color of the skin of buoy skin flap. The average amounts hypertrophied fibula at 12 months after operation were 20.6cm. And the following remarkable result were obtained. 1. With the uncontrolled bone infection, the vascularized osteocutaneous fibular transfer was able to be performed. 2. During the follow up period, the grafted fibula had been hypertrophied. 3. In roentgenogram, as compared with conventional bone graft, grafted bone was not resorbed and early united. 4. In adult, free fibula can be obtained and grafted as 23cm as long and the skin flap with fibula can be obtained and grafted as 21 × 7cm as large in or experience. 5. In the vascularized osteocutaneous fibula transfer, the patency of anastomoses was monitored indirectly by confirming skin flap. 6. The fractured fibula was united early by cast immobilization, and it was hypertrophied at the fracture site. 7. The vascularized osteocutaneous fibula transfer is also useful in application of the other long bones.
Adult ; Extremities ; Fibula ; Follow-Up Studies ; Fractures, Comminuted ; Fractures, Open ; Humans ; Hyperplasia ; Immobilization ; Microsurgery ; Necrosis ; Osteomyelitis ; Postoperative Period ; Skin ; Transplants

No abstract available.
Purpura, Schoenlein-Henoch*