No abstract available.
Diagnosis* ; Ultrasonography*

No abstract available.
Diagnosis* ; Ultrasonography*

No abstract available.
Teratoma*

The information obtained from epidemiology of brain tumor provide the key to the natural history of brain tumors and could be used for many different things, among others, the planning of hospitals and hospital care facilities and working out the medical requirements for each region. To cope with changing needs in this field due to the application of medical insurance to all Korean citizens from July 1. 1989, the brain tumor registries of various countries were reviewed and suggestions were made about Korean Brain Tumor Registry that should be prepared in the near future.
Brain Neoplasms* ; Brain* ; Epidemiology ; Insurance ; Korea* ; Natural History ; Registries

No abstract available.

Toxoplasmosis is a disease caused by the infection with an obligate intracellular parasite, Toxoplasma gondii. The most common manifestation of acute toxoplasmosis in an immunocompetent patients is a cervical lymphadenitis. The prevalence of toxoplasmosis in Korea is much lower than in those of other countries, including the United States and most European countries. We report three cases of toxoplasma lymphadenitis arising in the posterior cervical lymph nodes of immunocompetent patients with typical histologic findings and positive serologic results. The etiology, epidemiology, clinical features, diagnostic methods, and management of toxoplasmosis are also reviewed.
Epidemiology ; Humans ; Korea ; Lymph Nodes ; Lymphadenitis* ; Neck* ; Parasites ; Prevalence ; Toxoplasma* ; Toxoplasmosis ; United States

The authors performed a clinical analysis of 80 cases of pediatric brain tumors which were verified by surgical operation during 10 years from Sept. 1978 to Aug. 1987 in the Department of Neurosurgery, Korea University, Seoul, Korea. These tumors were divided according to modified WHO classification. The results were as follows: 1) The male to female ratio was 1.42:1. 2) The most common pediatric brain tumor was gliomas(48.7%), and followed by medulloblastome(17.5%), germ cell tumor(7.5%), craniopharyngioma(6.2%), meningioma(5.0%). 3) Supratentorial tumors(57.5%) were more frequent than infratentorial tumors(42.5%). 4) Headache and vomiting were the most common presenting symptoms and papilledema was the most common sign. 5) Hydrocephalus was developed at supratentorial(58.7%) and infratentorial(73.5%) region. 6) Postoperative mortality was 7%.
Brain Neoplasms* ; Brain* ; Child* ; Classification ; Female ; Germ Cells ; Glioma ; Headache ; Humans ; Hydrocephalus ; Korea ; Male ; Mortality ; Neurosurgery ; Papilledema ; Seoul ; Vomiting

The authors performed a clinical analysis of 80 cases of pediatric brain tumors which were verified by surgical operation during 10 years from Sept. 1978 to Aug. 1987 in the Department of Neurosurgery, Korea University, Seoul, Korea. These tumors were divided according to modified WHO classification. The results were as follows: 1) The male to female ratio was 1.42:1. 2) The most common pediatric brain tumor was gliomas(48.7%), and followed by medulloblastome(17.5%), germ cell tumor(7.5%), craniopharyngioma(6.2%), meningioma(5.0%). 3) Supratentorial tumors(57.5%) were more frequent than infratentorial tumors(42.5%). 4) Headache and vomiting were the most common presenting symptoms and papilledema was the most common sign. 5) Hydrocephalus was developed at supratentorial(58.7%) and infratentorial(73.5%) region. 6) Postoperative mortality was 7%.
Brain Neoplasms* ; Brain* ; Child* ; Classification ; Female ; Germ Cells ; Glioma ; Headache ; Humans ; Hydrocephalus ; Korea ; Male ; Mortality ; Neurosurgery ; Papilledema ; Seoul ; Vomiting

Fusion proteins resulting from chimeric sequences are excellent targets for therapeutic drug development. We developed a database of chimeric sequences by examining the genomic alignment of mRNA and EST sequences in the GenBank. We identified 688 chimeric mRNA and 20,998 chimeric EST sequences. Including EST sequences greatly expands the scope of chimeric sequences even though it inevitably accompanies many artifacts. Chimeric sequences are clustered according to the ECgene ID so that the user can easily find chimeric sequences related to a specific gene. Alignments of chimeric sequences are displayed as custom tracks in the UCSC genome browser. ChimerDB, available at http://genome.ewha.ac.kr/ECgene/ChimerDB/, should be a valuable resource for finding drug targets to treat cancers.
Artifacts ; Databases, Nucleic Acid* ; Genome ; RNA, Messenger ; Trans-Splicing ; Translocation, Genetic

PURPOSE: The objective of this retrospective study is to evaluate the practical feasibility and safety of applying hem-o-lok clips for the closure of the appendiceal stump in complicated appendicitis. METHODS: From January 2009 to April 2010, 267 patients who underwent laparoscopic appendectomies at the Pusan National University Yangsan Hospital were included in this study. Of these patients, 161 were diagnosed by computed tomography as having complicated acute appendicitis. In 107 patients, the appendiceal stump was closed with hem-o-lok clips, whereas in the remaining 160 patients, it was closed with endoloops. These two groups were compared for clinicopathologic data and procedural cost-effectiveness. RESULTS: No significant differences were found between the two groups in terms of age, sex, hospital stay, or blood loss. Furthermore, postoperative complications were similar and highly acceptable in both groups. However, operation times were significantly shorter and hospital cost was lower for the hem-o-lok group. CONCLUSION: The hem-o-lok clips has advantages such as simplicity of application, a shorter operation time, and lower hospital cost when used as a means of securing the base of the appendix in relation to the endoloop procedure.
Appendectomy ; Appendicitis ; Appendix ; Hospital Costs ; Humans ; Length of Stay ; Postoperative Complications ; Retrospective Studies