A 25 year old man presinted with erythematous and inderated plaques on the upper and lower extermities that were preceded by insect bites while traveling in central Africa. The patient had a past histrory of Kimura's disease, asthma, and allergic rhinitis, Histologic examination revealed panniculitls showing massive eosinophilic infiltration. The dermis showed eosinopbilic infilreatiom without flame figyres. The patient responded well to oral conrticosteroids. This patient did not fit the diagnosis of eosinoplilic pannicylitis, eosinophilic cellylitis, hypereosinophilic syndrome or eosinophilic vascylitis.
Africa, Central ; Asthma ; Dermis ; Diagnosis ; Eosinophils* ; Humans ; Hypereosinophilic Syndrome ; Insect Bites and Stings ; Rhinitis, Allergic ; Skin*

We report a case of fibrous hamartoma of infancy in a 7-month-old male infant, in which a solitary, asymptomatic, walnut-sized, nomal skin-colored plaque occurred on the left middle back for about one month. Histopathologic findings showed the distinctive features of fibrous hamartoma of infancy, ie, trabeculae of dense collagenous tissue, whorls of immature spindle cells within a mucoid matrix, and interspersed mature adipose tissue, in the lower dermis. The lesion was excised without recurrence.
Adipose Tissue ; Collagen ; Dermis ; Hamartoma* ; Humans ; Infant ; Male ; Recurrence

We herein report a case of keratoderma showing the combined clinical manifestations of striate and marginal keratoderma. The patient was a 18-year-old giri who about a year ago noticed slightly yellowish, well-circurnscribed, hyperkeratotic plaques on the volar aspect of the fingers and palms of both hands in a linear pattern with bands of hyperkeratotic plaques at the edeges of the 2nd fingers. We also found hyperkeratotic plaques on the both soles which were confined to sites of pressure. She denied a history of any chronic pressure or trauma. There was no family member showing the same clinical features. The histopathological findings from the palm, volsr aspect of finger and a sole revealed marked hyperkeratosis, hypergranulosis, and acanthosis.
Adolescent ; Fingers ; Hand ; Humans

No abstract available.
Animals ; Iproniazid* ; Monoamine Oxidase* ; Rats* ; Tyramine*

No abstract available.
Child* ; Humans ; Purpura, Thrombocytopenic, Idiopathic*

To determine the comparative accuracy of two Doppler tests, the findings of 38 patients who had undergone a complete evaluation by supraorbital Doppler test, frontal Doppler test and angiography were studied. When stenosis of 60 percent or more in diameter was considered as a true positive finding, the Doppler tests of 76 internal carotid arteries of the 38 patients showed the following results. Supraorbital Doppler test: eight false positive, three false negative, and 65 correct findings, with an overall accuracy of 85%. The authors, therefore, concluded that the suprorbital Doppler test was more sensitive and accurate than the frontal Doppler test in screening the patients with possible carotid artery occulusive diseases.
Angiography ; Carotid Arteries* ; Carotid Artery, Internal ; Constriction, Pathologic ; Humans ; Mass Screening

The recently proposed Bethesda system for cervical/vaginal cytology has made a standardization related to "atypia". In cellular changes due to inflammation or repair, the word "benign cellular change" has been suggested as a substitute for atypia. Terminology related to atypical cells may become standardized, but the cytologic criteria has not been well defined yet. We evaluated 160 cases of atypical squamous cells of undetermined significance(ASCUS) by the Bethesda System(TBS). Among 30,428 cases screened, a cytologic diagnosis of ASCUS was made in 498 cases(1.6%) and 160 cases were histologically verified. ASCUS was diagnosed based on nuclear enlargement and nonclassical signs of condyloma. The results are as follows: One hundred and twenty three cases(76.9%) revealed chronic cervicitis. Thirty seven cases(23.1%) demonstrated squamous intraepithelial lesion. Among intraepithelial lesions, condyloma and mild dysplasia were 28 cases(75.7%). Moderate and severe dysplasia were 5 cases(13.5%) and 4 cases(10.8%), respectively. It is concluded that patients with ASCUS should be colposcopically examined.
Breast ; Diagnosis ; Hemolytic-Uremic Syndrome* ; Humans ; Inflammation ; Pneumococcal Infections* ; Streptococcus pneumoniae* ; Streptococcus* ; Uterine Cervicitis

Immunohistochemial staining was performed in metastatic skin cancer using a variety of antistera. Both carcinoembrytonic antigen(CEA) and epithelial membrane antigen(EMA) were demonstrated in large cell carcinoma of the lung, adenocarcinoma of the stomach and skin adnexal cancer with eccrine differentiation. Although papillary carcinoma of the thyroid, squamous cell carcinoma of the skin and squamous cell carcinoma of the lung showed positive staining for CEA and EMA, these were weak or focal reactions in the keratinizing area. In rectal adenocarcinoma, staining for CEA was significantly positive, but staining for EMA was negative. Epiderrnal cytokeratin was observed in squamous cell carcinoma of the lung, squamous cell carcinoma of the skin and skin adnexal cancer with eccrine differentiation. Epidermal cytokeratin was also demonstrated in well differentiated adenocarcinoma of the gastrointestinal tract. By using a variety of tumor markers, the authors tried to locate possible primary sites in six metastatic skin cancers of unknown origin.
Adenocarcinoma ; Carcinoma, Large Cell ; Carcinoma, Papillary ; Carcinoma, Squamous Cell ; Gastrointestinal Tract ; Keratins ; Lung ; Membranes ; Skin Neoplasms* ; Skin* ; Stomach ; Thyroid Gland ; Biomarkers, Tumor

During the past 2 years : June, 1985 to May, 1987, 564 cases with dermatophytosis who visited the Dermatology Clinic of Wonju Christian Hospital were studied for Microeporam(M,) canis infection by mycologieal examination. The incidence of M.canis infection found to be 16.3%. The monthly distribotion was the highest in January and lowest in August. The ratio of male to female patient was 1: 1. Most of the cases (80.0%) were found in children under the age of 10. Tinea capitis was the most common clinical type of dermatophytosis caused by M. canis. Patients who had a history of contact with domestic cats (27.5%) or dogs (6.3%) were observed in 27 cases and family infections were observed in 22 cases. The incidence of patients with the noninflammatory and inflammatory lesions in tinea cspitis was similar. Most of patients with tinea corporis exhibited multiple, smaller than 2 cm in diameter, annular patches having pustules or papules.
Animals ; Cats ; Child ; Dermatology ; Dogs ; Female ; Gangwon-do* ; Humans ; Incidence ; Male ; Microsporum* ; Tinea ; Tinea Capitis

We describe an unusual case of leptomenigeal carcinomatosis presented with bilateral blindness. A 67-year old male had been suffering from progressive blindness for the past 2 months. Initially, the symptom developed in the right eye but quickly spread to the left eye becoming bilateral with complete vision loss in a matter of weeks. He did not show any other focal neurological signs and did not have a history of malignancy. An examination of the cerebrospinal fluid revealed metastatic adenocarcinoma. As this case indicated, the patients of leptomeningal metastasis may present with acute or subacute blindness, even in the absence of other focal neurological deficits.
Adenocarcinoma ; Aged ; Blindness ; Carcinoma ; Cerebrospinal Fluid ; Humans ; Male ; Neoplasm Metastasis*