No abstract available.
Denture, Complete* ; Finite Element Analysis*

Epidemiological evidence suggests that human papillomavirus(HPV) infection is a high risk factor for the development of oral cancers. Many oncogenes, especially p53 suppressor gene, have a critical role of carcinogenesis in several human cancers including oral cancers. To investigate the prevalence of HPV infection and subtyping of high risk group(HPV-16, -18 and -33) HPV in oral cancers, the author studied 31 cases of squamous cell carcinomas arising from the oral cavity using polymerase chain reaction (PCR). The author also demonstrated the overexpression of p53 oncoprotein in the oral cancers using immunohistochemical methods. The correlation between HPVs infection and p53 overexpression in tumorigenesis of the oral cancers was evaluated. 1. Twenty-one cases(66.7%) among 31 cases of oral squamous cell carcinomas were positive for HPV-DNA. Among them, 16 cases were positive for HPV-16, 4 cases for HPV-18, and 2 cases for HPV-33. Two cases were coinfected with HPV-16 and HPV-18, and HPV-18 and HPV-33. 2. The prevalence of HPV infection appeared not correlated with tumor differentiation and clinical stages of oral squamous cell carcinomas. 3. The overexpression of p53 oncoprotein was present in 24 of 31 cases(77% ). In 21 HPV positive tumors 18 cases were positive for overexpression of p53 oncoprotein. Six cases were positive for p53 in ten HPV negative tumors. There was no correlation between HPV DNA detection rate and p53 overexpression. The above results suggest that HPV infection and p53 oncogene mutation play different roles in tumorigenesis of oral squamous cell carcinomas. No coexpression of p53 oncoprotein with HPV-DNA detection suggests that another etiologic mechanism other than HPV infection may be operative.
Carcinogenesis ; Carcinoma, Squamous Cell* ; DNA ; Genes, Suppressor ; Human papillomavirus 16 ; Human papillomavirus 18 ; Humans* ; Mouth Neoplasms ; Mouth* ; Oncogenes ; Polymerase Chain Reaction ; Prevalence ; Risk Factors

Antibodies, Antinuclear ; Arthritis, Rheumatoid ; Autoimmune Diseases ; Biopsy ; Brain ; Butterflies ; Drug Therapy ; Endothelium ; Female ; Humans ; Immune System ; Liver ; Lupus Erythematosus, Systemic ; Lymph Nodes ; Lymphoma ; Maxilla ; Middle Aged ; Oncogenic Viruses ; Sjogren's Syndrome

A study was made of the differences in clinical features and immunological aspects between herpes zoster patients with malignancies and those without malignant tumors. The results obtained from the retrospective review of medical records are as follows: Herpes zoster occurred more frequently in younger patients(less than twenty) with malignanciee as compared with the control group of the same ages,' Male was dominant among zoster patients with malignancies as is the contrary to contral group; Tihere were no marked differences in primarilly involved dermatomes between the two groups; Generalized varicelliform eruptiona were more common in zoster pa,tients with malignaneies than in control group, It seemed that zoster patients with malignancies complained of milder degree of pain. Zoeter patienta associated with malignancies were more frequently DNCB-negative and had decreased OKT3+ pan T cells, OKT4+ helper/inducer T cells as compared with control group, which suggest impaired cell mediated immunity in the former.
Herpes Zoster* ; Humans ; Immunity, Cellular ; Male ; Medical Records ; Retrospective Studies ; T-Lymphocytes

The purpose of this study was to analyze the relationship among the health promoting behaviors, self-reported climacteric symptoms and depression on a cross-sectional survey design. The subjects were 108 middle-aged women who were non-hystrectomized and ranged in age from 40 to 60. They were selected in Seoul and Kyoung-ki province, Korea. Data were collected from Oct. 25 to Nov. 10, 1997 by a structured questionnaire. The instrument used for this study was the revised Health Promotion Lifestyle Profile(HPLP) developed by Walker, Sechrist and Pender, revised Climacteric Symptoms Scale developed by Chi, Sung Ai, and the Beck's Depression Inventory(BID). The data were analyzed by the SPSS/PC+ program using t-test, ANOVA and Scheffe test as a post hoc and Pearson Correlation Coefficient. The results of the study were as follows ; 1. The mean score of health promoting behaviors was low(2.42+/-0.35). There were statistically significant difference in the score of health promoting behaviors according to the educational background, family income, marital satisfaction, and whether or not taking a restorative food(t=-2.07, F=2.60~7.57, p<0.05). 2. The mean score of self-reported climacteric symptoms was 1.69 ; 99% of middle-aged women had symptoms. There were statistically significant difference in the score of middle-aged women's self-reported climacteric symptoms according to the age, number of children, educational background, occupation, family income, marital satisfaction, whether or not receiving hormone replacement therapy(HRT) or consultation experience with a professional, and perceived health status(t=-2.04~3.69, F=2.87~11.63, p<0.05). 3. The mean score of depression was 10.84. There were statistically significant differences in the score of the depression according to the age, number of children, educational background, occupation, marital satisfaction, whether or not receiving menopausal treatment of consultation by a professional, and perceived health status(t=-2.25~3.00, F=3.50~9.24, p<0.05). 4. Women's degree of health promoting behaviors was a negative correlation with the degree of climacteric symptoms(r=-0.19, p=0.03) and the degree of depression(r=-0.23, p=0.01). The degree of climacteric symptoms was a positive correlation with the degree of depression(r=0.64, p=0.01). In conclusion, health promoting behavior should be considered when developing nursing strategies for middle-aged women, especially when dealing with climacteric symptoms and depression.
Child ; Climacteric* ; Cross-Sectional Studies ; Depression* ; Female ; Health Promotion ; Humans ; Korea ; Life Style ; Menopause ; Nursing ; Occupations ; Surveys and Questionnaires ; Seoul

Background & PURPOSE:Since the 1970's the rate of breast-feeding has decreased significantly. The Korean National Institute of Health reported that the rate of breastfeeding was 68.9% in 1982 and 14.1% in 1997. There are many influencing factors including: the lack of education and information on breast feeding, lack of faith in breast feeding, increment of the rate of working, lack of encouragement by supporters in difficult situations, and nurses' low level of knowledge about breast feeding. Such a lack of knowledge and support of breast-feeding at home by family members create another dilemma to the problem of breast-feeding. If problems arise and family members are unable to provide assistance due to the deficiency of knowledge, mothers show a tendency to abandon breast-feeding. The purpose of this research is to find out the rate of breast-feeding practice by time sequence of 1 week, 6 weeks and 12 weeks after birth and influencing factors on breast-feeding practice centered on the postpartal women who were 3discharged from one hospital, which is located in Seoul and provides simple breast-feeding education and continuous postnatal telephone consultation. Methodology: The subjects of this research were 54 women who gave birth in a hospital located in Seoul from 1 March 2000 to 31 April 2000. After birth the subjects were educated individually about breast-feeding and telephone consultations were conducted. On the 1st week, 6th week, and 12th week, the subjects were surveyed about their breast-feeding practice rates and methods by telephone. Results: 1) Complete breast-feeding rate: Within one week after birth, the subjects showed 64.2% complete breast-feeding rate. Within 6 weeks, 39.6%, and 12 weeks, 34.1%. 2)Partial breast-feeding rate: Within one week after birth, the subjects showed 32.1% partial breast-feeding rate. Within 6 weeks, 39.6%, and 12 weeks 15.1%. 3)Complete bottle-feeding rate Within one week after birth, the subjects showed 1.9% complete bottle-feeding rate. Within 6 weeks of giving birth 15.1%, and 12 weeks 17.0%. These results show that individual education about breast-feeding and continuous postnatal telephone consultation influenced on the practice of breast-feeding. On considering the reality of the hospital situation in which nurses could not operate education program due to the work-load, it is necessary to find out selectively those mothers who are unable to breast feed and provide education individually and continuous support by telephone follow up. Futhermore, the active role of lactation nurse specialist and their efficient management of breast-feeding for the successful practice is required.
Breast ; Breast Feeding ; Education* ; Female ; Follow-Up Studies* ; Humans ; Lactation ; Mothers ; Parturition ; Referral and Consultation ; Seoul ; Specialization ; Telephone*

Dermatofibrosarcoma protuberans is an uncommon, locally aggressive fibroblastic tumor, characterized by infrequent metastasis and a marked tendency of local recurrence after excision. Histologically, it shows large uniformed spindle shaped cells arranged in a cartwheel or storiform pattern. We report a case of dermatoribrosarcoma protuberans on the lower abdomen of a man aged of thirty, treated with Mohs micrographic surgery and purse-string suture repair.
Abdomen ; Dermatofibrosarcoma* ; Fibroblasts ; Mohs Surgery* ; Neoplasm Metastasis ; Recurrence ; Sutures*

The purpose of this study was pertinent design of the framework of the fixed bone anchored bridge using implants in the edentulous mandible through analysis of stress distribution by the three dimensional finite element analysis method. The results were as follows: 1. The L-shaped framework was favorable in restoring the edentulous mandible by implants and fixed bone anchored bridge. 2. The structure of the framework should be designed to endure the occlusal load because of stress concentration at the most distal abutment of the framework. 3. The stress at the distal implant where cantilever starts was twice as much as that of other portions. 4. Compressive stress was generated on the framework of the mesial side of the distal implant and extrusive force was induced to the mesially positioned implants. 5. The height of vertical plate was high as possible as can be to distribute stresses concentrating bucco-lingually and labio-lingually in the framework between abutments, 6. Reinforcement of the horizontal plate thickness was needed because stress was loaded more on the horizontal plate than on the vertical plate of the framework. 7. Lengthening of the vertical plate can compensate for any limitations in horizontal plate width.
Dental Implants* ; Finite Element Analysis ; Mandible ; Suture Anchors*

PURPOSE: The purpose of this study was to discover kidney transplant and hemodialysis patients' quality of life(QOL) and provide basic data to improve their QOL. METHOD: One hundred two hemodialysis patients and 106 kidney transplant patients were given a self-administered questionnaire from Mar. 6 to Mar. 31, 2006. The instrument consisted of demographic variables, therapeutic-related characteristics and QOL. Collected data was processed using the SPSS 12.0 statistical program for real numbers, percentages, ANCOVA, t-test, ANOVA, Stepwise multiple regression and the Scheffe test. RESULTS: Kidney transplantpatients' QOL was higher than hemodialysis patients. The demographic variables which showed a significant difference in overall QOL were religion, children and monthly income for kidney transplantpatients and educational background for hemodialysis patients. The therapeutic-related variable which showed a significant difference in overall QOL was the patients' perceived health condition for both groups. The influencing factor on overall QOL for both groups was the health condition perceived by themselves. The total variance of the variable for QOL was 42% for kidney transplant patients and 19% for hemodialysis patients. CONCLUSION: This study revealed that kidney transplant patients have a higher QOL and how patients perceive their health is the strongest influencing factor for QOL. However, there is a large difference between the demand and supply of kidney donors. To solve this problem the standards for donation should be reviewed and revised.
Adult ; Aged ; Aged, 80 and over ; Demography ; Female ; Health Status ; Humans ; Kidney Transplantation/nursing/*psychology ; Male ; Middle Aged ; *Quality of Life ; Questionnaires ; Renal Dialysis/nursing/*psychology ; Tissue Donors

A 65-year-old female patient visited our clinic complaining of multiple skin lesions since one year ago. There were yellowish to brownish colored, bean to walnut-sized nodules on both lower extremities. Dylon stain with polarizing microscopy, immunohistochemical stain to amyloid P and immunoglobuhn-kappa chain showed positive reactivities but keratin stain was negative. According to histopathologic and immunohistochemical findings, she was diagnosed as nodular amyloidosis.
Aged ; Amyloid ; Amyloidosis* ; Female ; Humans ; Lower Extremity ; Microscopy ; Skin