1.Immunohistological study of lymph follicles and germinal centers in the politeal lymph nodes of developing mice after injection of mitogen and adjuvant.
Kwang Joon AHN ; Won Kyu LEE ; Hee Kyung AHN
Korean Journal of Anatomy 1992;25(3):274-288
No abstract available.
Animals
;
Germinal Center*
;
Lymph Nodes*
;
Mice*
2.A Case of Pigmented Villonodular Synovitis
Kwang Hoe KIM ; Hee Soo RHEE ; Syng Won SOHN
The Journal of the Korean Orthopaedic Association 1970;5(2):79-82
A case of pigmented villonodular synovitis developed in the right ankle joint is reported. The patient was a 25 years old house wife who had complained marked swelling and tenderness over the anterolateral aspect of the right ankle for 2 years. Roentgenological studies showed marked swelling of the ankle joint and erosion of the neck of the talus. Synovectomy of the affected joint was performed. The tumor mass, measuring about 7cm×5cm×2cm in size, was yellowish brown in colour, elastic and soft in consistency, and contained several well encapsulated nodules.
Ankle
;
Ankle Joint
;
Humans
;
Joints
;
Neck
;
Spouses
;
Synovitis, Pigmented Villonodular
;
Talus
3.A Case of Buschke-Lowenstein Tumor in Renal Transplant Recipient.
Kwang Hoon LEE ; Ju Hee LEE ; Won Soon CHUNG ; Kee Yang CHUNG ; Kwang Hoon LEE
Annals of Dermatology 2002;14(3):164-167
Buschke-Lowenstein tumor is a rare disease in the category of designated as verrucous carcinoma characterized by its invasive downward penetration of underlying tissues in the perineum and perianal regions. Viruses, unclean sanitation and cytotoxic immune reaction have been proposed as the etiology of the tumor. However, among all the causes, recent studies have emphasized on the associaton of the tumor and human papilloma virus (HPV). Expecially, HPV also has been discovered in several cutaneous and anogenital lesions of solid organ transplant recipients. We herein report a case of Buschke-Lowenstein tumor in a renal transplant recipient with HPV 6 and 16 coinfection proved by HPV genotyping of DNA extracted from the biopsy specimen of the tumor.
Biopsy
;
Buschke-Lowenstein Tumor*
;
Carcinoma, Verrucous
;
Coinfection
;
DNA
;
Human papillomavirus 6
;
Humans
;
Papilloma
;
Perineum
;
Rare Diseases
;
Sanitation
;
Transplantation*
;
Transplants
4.Collision carcinoma in a metastatic neck node.
Sun Hee LEE ; Kwang Yoon JUNG ; Jong Ouck CHOI ; Sang Ae YOON ; Nam Hee WON
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(3):410-413
No abstract available.
Neck*
5.Inhibitory of γ-aminobutyric acid on the contractility of isolated rat vas deferens.
Ki Young AHN ; Oh Cheol KWON ; Jeoung Hee HA ; Kwang Youn LEE ; Won Joon KIM
Yeungnam University Journal of Medicine 1992;9(2):382-395
GABA is an inhibitory neurotransmitter in central nervous system and produce sedative, antianxiety and muscle relaxing effects via GABA(A) receptor or GABA(B) receptor. Recently it is known that GABA is widely distributed throughout peripheral organs and may play a physiological role in certain organ. The vas deferens is innervated by species-difference. These study, therefore, was performed to investigate the mode and the mechanism of action of GABA on the norepinephrine-, ATP- and electric stimulation-induced contraction of vas deferens of rat. Sprague-Dawley rats were sacrificed by cervical dislocation. The smooth muscle strips were isolated from the prostatic portion and were mounted in the isolated muscle bath. PSS in the bath was aerated with 95/5%-O₂/CO₂ at 33℃. Muscle tensions were measured by isometric tension transducer and were recorded by biological recording system. 1. GABA, muscimol, a GABA(A) agonist, and baclofen, a GABA(B) agonist inhibited the electric field stimulation (EFS, 0.2Hz, 1mSec, 80V, monophasic square wave)-induced contraction with a rank order of potency of GABA greater than baclofen greater than muscimol. 2. The inhibitory effect of GABA was antagonized by delta aminovaleric acid (DAVA), a GABA(B) antagonist, but not by bicuculline, a GABA(A) intagonist. 3. The inhibitory effect of baclofen was antagonized by DAVA, but the effect of muscimol was not antagonized by bicuculline. 4. Exogenous norepinephrine (NE) and ATP contracted muscle strip concentration dependently, but the effect of acetylcholine was negligible and GABA did not affect the NE-and ATP-induced contractions. 5. GABA, baclofen and muscimol did not affect basal tone, and GABA did not affect the NE-and ATP-induced contractions. 6. EFS-induced contraction was inclucling 2 distinctable components. The first phasic component was inhibited by beta gamma-methylene ATP (mATP), a desensitizing agent of APT receptor and the second tonic component was reduced by pretreatment of reserpine (3 mg/Kg, IP). 7. GABA inhibited the EFS-induced contraction of reserpinized strips, but not the mATP-treated strips. These results suggest that in the prostatic portion of the rat vas deferens, adrenergic and purinergic neurotransmissions are exist, and GABA inhibits the release of ATP via presynaptic GABA(B) receptor on the excitatory neurons.
Acetylcholine
;
Adenosine Triphosphate
;
Animals
;
Baclofen
;
Baths
;
Bicuculline
;
Central Nervous System
;
Dislocations
;
gamma-Aminobutyric Acid
;
Muscimol
;
Muscle, Smooth
;
Neurons
;
Neurotransmitter Agents
;
Norepinephrine
;
Rats*
;
Rats, Sprague-Dawley
;
Receptors, GABA-A
;
Reserpine
;
Transducers
;
Vas Deferens*
6.The Effects of Diazepam on the Carbachol Induced Contraction of the Isolated Rat Ileum.
Jung Ok KIM ; Oh Cheol KWON ; Jeoung Hee HA ; Kwang Youn LEE ; Won Joon KIM
Yeungnam University Journal of Medicine 1989;6(2):13-22
To investigate the effect of diazepam on the contractility of the intestinal smooth muscle, longitudinal muscle strip isolated from rat ileum was prepared for myography in isolated organ bath. 1) Basal tone of ileal muscle was reduced by diazepam concentration-dependently. 2) Higher concentrations (30 and 100 microM) of diazepam inhibited (p<0.05, p<0.001) The carbachol-induced contraction in a concentration-dependent manner; but lower concentration of diazepam (10 microM) enhanced (p<0.05). 3) Histamine-induced contraction was inhibited by pretreatment with diazepam in a concentration-dependent manner. 4) Ca⁺⁺-induced tension recovery in calcium-free solution was inhibited in the presence of diazepam concentration-dependently. These results suggest diazepam reduces the contractility of the longitudinal muscle isolated from rat ileum via interference with influx of calcium into the muscle cells.
Animals
;
Baths
;
Calcium
;
Carbachol*
;
Diazepam*
;
Ileum*
;
Muscle Cells
;
Muscle, Smooth
;
Myography
;
Rats*
7.A case of impetigo herpertiformis.
Hyeok Jin KWEON ; Kwang Young PARK ; Jae Kyung PARK ; Sang Won KIM ; Nan Hee KIM
Korean Journal of Dermatology 1991;29(5):653-657
No abstract available.
Impetigo*
8.In vitro growth of candida albicans on several resilient dinture liners.
Chae Heon CHUNG ; Kwang Won KIM ; Dong Ki KIM ; Zang Hee LEE
The Journal of Korean Academy of Prosthodontics 1993;31(1):19-27
No abstract available.
Candida albicans*
;
Candida*
9.The Significance of Palliative Nephrostomy.
Young Sun KIM ; Kwang Myung KIM ; Won Hee PARK ; Si Whang KIM
Korean Journal of Urology 1982;23(8):1085-1088
Palliative open nephrostomy was done on 50 cases with advanced pelvic malignancy and benign conditions in the Department of Urology, Seoul National University Hospital during the period of March, 1979 to July, 1982. The results were as follows: 1. 20.5% (9/44) of our patients died without being discharged from the hospital after nephrostomy. 2. In advanced pelvic malignancy, only 52.6% of patients alive at 3 months and only 26.3% alive 6 months. 3. In advanced pelvic malignancy, the post-nephrostomy complication was 46.7% and the most common complication was various urinary problems. 4. The cause of death was multifactorical and impossible to define precisely. The nephrostomy complications were at least in part contributory to the deaths. 5. The terminal malignancy patients who might not expected to live six months and to lead a useful, relatively comfortable life outside the hospital after treatment could not have benefited from nephrostomy. Unavoidable cases, we recommended percutaneous nephrostomy and passage of ureteral catheters instead of open nephrostomy.
Cause of Death
;
Humans
;
Nephrostomy, Percutaneous
;
Seoul
;
Urinary Catheters
;
Urology
10.Effect of Carbamazepine on the Ouabain-Induced Arrhythmia in Rabbits.
Eui Hong KIM ; Jeoung Hee HA ; Kwang Youn LEE ; Won Joon KIM
Yeungnam University Journal of Medicine 1986;3(1):279-285
Carbamazepine is a derivative of iminostilbene with carbamoyl group and related chemically to the tricyclic antidepressants. Carbamazepine has been introduced for treatment of trigeminal neuralgia. Recently it is used as an antiepileptic agent such as diphenylhydantoin. Antiepileptic drugs are known to affect experimentally induced cardiac arrhythmia and are now widely used clinically for treatment of ventricular tachyarrhythmias, particularly those produced by digitalis intoxication. Steiner et al. (1970) reported that carbamazepine was found to be very effective in converting ventricular tachycardia due to digitalis toxicity to normal sinus rhythm. Clinically bradycardia, complete heart block, ventricular standstill and Adams-stokes attack were reported in the course of carbamazepine treatment. The purpose of this study was to investigate the effects of carbamazepine on the ouabain-induced arrhythmia in vivo. The rabbits of either sex, weighing from 1.6 to 3.2 kg were anesthetized by urethane. After the trachea was cannulated, the rabbits were ventilated with room air using a respirator. Drugs were given into polyethylene cannula in the femoral vein. Blood pressure were recorded by physiograph via pressure tranducer connected with the cannula in the femoral artery. EKG were recorded by physiograph via electrode implanted in both fore leg and left hind leg. The results are summarized as follows 1. Arrhythmia was induced by continuous infusion of ouabain (65±8.8 µg/kg). 2. Single administration of ouabain (64 µg/kg) induced arrhythmia which was persisted for 7-8 min. 3. Ouabain induced arrhythmia was restored to normal sinus rhythm by administration of carbamazepine (the more dosage, the less frequent and the longer duration). 4. Severe bradycardia, A-V block, atrial fibrillation were seen on the EKG after injection of carbamzepine alone. By the above results, it may be concluded that carbamzepine inhibits the ouabain-induced arrhythmia by dose-dependent.
Anticonvulsants
;
Antidepressive Agents, Tricyclic
;
Arrhythmias, Cardiac*
;
Atrial Fibrillation
;
Blood Pressure
;
Bradycardia
;
Carbamazepine*
;
Catheters
;
Digitalis
;
Electrocardiography
;
Electrodes
;
Femoral Artery
;
Femoral Vein
;
Heart Block
;
Leg
;
Ouabain
;
Phenytoin
;
Polyethylene
;
Rabbits*
;
Tachycardia
;
Tachycardia, Ventricular
;
Trachea
;
Trigeminal Neuralgia
;
Urethane
;
Ventilators, Mechanical