1.Immunohistological study of lymph follicles and germinal centers in the politeal lymph nodes of developing mice after injection of mitogen and adjuvant.
Kwang Joon AHN ; Won Kyu LEE ; Hee Kyung AHN
Korean Journal of Anatomy 1992;25(3):274-288
No abstract available.
Animals
;
Germinal Center*
;
Lymph Nodes*
;
Mice*
2.A Case of Pigmented Villonodular Synovitis
Kwang Hoe KIM ; Hee Soo RHEE ; Syng Won SOHN
The Journal of the Korean Orthopaedic Association 1970;5(2):79-82
A case of pigmented villonodular synovitis developed in the right ankle joint is reported. The patient was a 25 years old house wife who had complained marked swelling and tenderness over the anterolateral aspect of the right ankle for 2 years. Roentgenological studies showed marked swelling of the ankle joint and erosion of the neck of the talus. Synovectomy of the affected joint was performed. The tumor mass, measuring about 7cm×5cm×2cm in size, was yellowish brown in colour, elastic and soft in consistency, and contained several well encapsulated nodules.
Ankle
;
Ankle Joint
;
Humans
;
Joints
;
Neck
;
Spouses
;
Synovitis, Pigmented Villonodular
;
Talus
3.A Case of Buschke-Lowenstein Tumor in Renal Transplant Recipient.
Kwang Hoon LEE ; Ju Hee LEE ; Won Soon CHUNG ; Kee Yang CHUNG ; Kwang Hoon LEE
Annals of Dermatology 2002;14(3):164-167
Buschke-Lowenstein tumor is a rare disease in the category of designated as verrucous carcinoma characterized by its invasive downward penetration of underlying tissues in the perineum and perianal regions. Viruses, unclean sanitation and cytotoxic immune reaction have been proposed as the etiology of the tumor. However, among all the causes, recent studies have emphasized on the associaton of the tumor and human papilloma virus (HPV). Expecially, HPV also has been discovered in several cutaneous and anogenital lesions of solid organ transplant recipients. We herein report a case of Buschke-Lowenstein tumor in a renal transplant recipient with HPV 6 and 16 coinfection proved by HPV genotyping of DNA extracted from the biopsy specimen of the tumor.
Biopsy
;
Buschke-Lowenstein Tumor*
;
Carcinoma, Verrucous
;
Coinfection
;
DNA
;
Human papillomavirus 6
;
Humans
;
Papilloma
;
Perineum
;
Rare Diseases
;
Sanitation
;
Transplantation*
;
Transplants
4.Collision carcinoma in a metastatic neck node.
Sun Hee LEE ; Kwang Yoon JUNG ; Jong Ouck CHOI ; Sang Ae YOON ; Nam Hee WON
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(3):410-413
No abstract available.
Neck*
5.The Effects of Diazepam on the Carbachol Induced Contraction of the Isolated Rat Ileum.
Jung Ok KIM ; Oh Cheol KWON ; Jeoung Hee HA ; Kwang Youn LEE ; Won Joon KIM
Yeungnam University Journal of Medicine 1989;6(2):13-22
To investigate the effect of diazepam on the contractility of the intestinal smooth muscle, longitudinal muscle strip isolated from rat ileum was prepared for myography in isolated organ bath. 1) Basal tone of ileal muscle was reduced by diazepam concentration-dependently. 2) Higher concentrations (30 and 100 microM) of diazepam inhibited (p<0.05, p<0.001) The carbachol-induced contraction in a concentration-dependent manner; but lower concentration of diazepam (10 microM) enhanced (p<0.05). 3) Histamine-induced contraction was inhibited by pretreatment with diazepam in a concentration-dependent manner. 4) Ca⁺⁺-induced tension recovery in calcium-free solution was inhibited in the presence of diazepam concentration-dependently. These results suggest diazepam reduces the contractility of the longitudinal muscle isolated from rat ileum via interference with influx of calcium into the muscle cells.
Animals
;
Baths
;
Calcium
;
Carbachol*
;
Diazepam*
;
Ileum*
;
Muscle Cells
;
Muscle, Smooth
;
Myography
;
Rats*
6.Inhibitory of γ-aminobutyric acid on the contractility of isolated rat vas deferens.
Ki Young AHN ; Oh Cheol KWON ; Jeoung Hee HA ; Kwang Youn LEE ; Won Joon KIM
Yeungnam University Journal of Medicine 1992;9(2):382-395
GABA is an inhibitory neurotransmitter in central nervous system and produce sedative, antianxiety and muscle relaxing effects via GABA(A) receptor or GABA(B) receptor. Recently it is known that GABA is widely distributed throughout peripheral organs and may play a physiological role in certain organ. The vas deferens is innervated by species-difference. These study, therefore, was performed to investigate the mode and the mechanism of action of GABA on the norepinephrine-, ATP- and electric stimulation-induced contraction of vas deferens of rat. Sprague-Dawley rats were sacrificed by cervical dislocation. The smooth muscle strips were isolated from the prostatic portion and were mounted in the isolated muscle bath. PSS in the bath was aerated with 95/5%-O₂/CO₂ at 33℃. Muscle tensions were measured by isometric tension transducer and were recorded by biological recording system. 1. GABA, muscimol, a GABA(A) agonist, and baclofen, a GABA(B) agonist inhibited the electric field stimulation (EFS, 0.2Hz, 1mSec, 80V, monophasic square wave)-induced contraction with a rank order of potency of GABA greater than baclofen greater than muscimol. 2. The inhibitory effect of GABA was antagonized by delta aminovaleric acid (DAVA), a GABA(B) antagonist, but not by bicuculline, a GABA(A) intagonist. 3. The inhibitory effect of baclofen was antagonized by DAVA, but the effect of muscimol was not antagonized by bicuculline. 4. Exogenous norepinephrine (NE) and ATP contracted muscle strip concentration dependently, but the effect of acetylcholine was negligible and GABA did not affect the NE-and ATP-induced contractions. 5. GABA, baclofen and muscimol did not affect basal tone, and GABA did not affect the NE-and ATP-induced contractions. 6. EFS-induced contraction was inclucling 2 distinctable components. The first phasic component was inhibited by beta gamma-methylene ATP (mATP), a desensitizing agent of APT receptor and the second tonic component was reduced by pretreatment of reserpine (3 mg/Kg, IP). 7. GABA inhibited the EFS-induced contraction of reserpinized strips, but not the mATP-treated strips. These results suggest that in the prostatic portion of the rat vas deferens, adrenergic and purinergic neurotransmissions are exist, and GABA inhibits the release of ATP via presynaptic GABA(B) receptor on the excitatory neurons.
Acetylcholine
;
Adenosine Triphosphate
;
Animals
;
Baclofen
;
Baths
;
Bicuculline
;
Central Nervous System
;
Dislocations
;
gamma-Aminobutyric Acid
;
Muscimol
;
Muscle, Smooth
;
Neurons
;
Neurotransmitter Agents
;
Norepinephrine
;
Rats*
;
Rats, Sprague-Dawley
;
Receptors, GABA-A
;
Reserpine
;
Transducers
;
Vas Deferens*
7.A Case of Dermatofibrosarcoma Protuberans Treated with Mohs Micrographic Surgery and Purse - String Suture Repair.
Yoo Won CHOI ; Kyu Kwang WHANG ; Jeong Hee HAHM ; Jung Bock LEE
Korean Journal of Dermatology 1995;33(6):1108-1113
Dermatofibrosarcoma protuberans is an uncommon, locally aggressive fibroblastic tumor, characterized by infrequent metastasis and a marked tendency of local recurrence after excision. Histologically, it shows large uniformed spindle shaped cells arranged in a cartwheel or storiform pattern. We report a case of dermatoribrosarcoma protuberans on the lower abdomen of a man aged of thirty, treated with Mohs micrographic surgery and purse-string suture repair.
Abdomen
;
Dermatofibrosarcoma*
;
Fibroblasts
;
Mohs Surgery*
;
Neoplasm Metastasis
;
Recurrence
;
Sutures*
8.A Study on the Rate of Breast-feeding Practice by Education and Continuous Telephone Follow-up.
Eun Kwang YOO ; Myoung Hee KIM ; Won Shim SEO
Korean Journal of Women Health Nursing 2002;8(3):424-434
Background & PURPOSE:Since the 1970's the rate of breast-feeding has decreased significantly. The Korean National Institute of Health reported that the rate of breastfeeding was 68.9% in 1982 and 14.1% in 1997. There are many influencing factors including: the lack of education and information on breast feeding, lack of faith in breast feeding, increment of the rate of working, lack of encouragement by supporters in difficult situations, and nurses' low level of knowledge about breast feeding. Such a lack of knowledge and support of breast-feeding at home by family members create another dilemma to the problem of breast-feeding. If problems arise and family members are unable to provide assistance due to the deficiency of knowledge, mothers show a tendency to abandon breast-feeding. The purpose of this research is to find out the rate of breast-feeding practice by time sequence of 1 week, 6 weeks and 12 weeks after birth and influencing factors on breast-feeding practice centered on the postpartal women who were 3discharged from one hospital, which is located in Seoul and provides simple breast-feeding education and continuous postnatal telephone consultation. Methodology: The subjects of this research were 54 women who gave birth in a hospital located in Seoul from 1 March 2000 to 31 April 2000. After birth the subjects were educated individually about breast-feeding and telephone consultations were conducted. On the 1st week, 6th week, and 12th week, the subjects were surveyed about their breast-feeding practice rates and methods by telephone. Results: 1) Complete breast-feeding rate: Within one week after birth, the subjects showed 64.2% complete breast-feeding rate. Within 6 weeks, 39.6%, and 12 weeks, 34.1%. 2)Partial breast-feeding rate: Within one week after birth, the subjects showed 32.1% partial breast-feeding rate. Within 6 weeks, 39.6%, and 12 weeks 15.1%. 3)Complete bottle-feeding rate Within one week after birth, the subjects showed 1.9% complete bottle-feeding rate. Within 6 weeks of giving birth 15.1%, and 12 weeks 17.0%. These results show that individual education about breast-feeding and continuous postnatal telephone consultation influenced on the practice of breast-feeding. On considering the reality of the hospital situation in which nurses could not operate education program due to the work-load, it is necessary to find out selectively those mothers who are unable to breast feed and provide education individually and continuous support by telephone follow up. Futhermore, the active role of lactation nurse specialist and their efficient management of breast-feeding for the successful practice is required.
Breast
;
Breast Feeding
;
Education*
;
Female
;
Follow-Up Studies*
;
Humans
;
Lactation
;
Mothers
;
Parturition
;
Referral and Consultation
;
Seoul
;
Specialization
;
Telephone*
9.STRESS ANALYSIS OF ABUTMENT FOR DISTAL EXTENSION REMOVABLE PARTIAL DENTURE BY CLASP DESIGN AND IMPRESSION METHOD.
Hee Young AHN ; Kwang Jun KIM ; Hye Won CHO ; Tai Ho JIN
The Journal of Korean Academy of Prosthodontics 2001;39(5):547-555
This study was performed to investigate the effects of impression method and design of the retainer on the stress of abutment tooth in distal extension RPD. Three different types of direct retainer such as Akers clasp. RPI clasp, and wrought wire clasp were designed . Stress on the abutment tooth was measured and analyzed with strain gauge method. Impressions were anatomic impression technique and functional impression technique. The following conclusions were drawn from this syudy. 1.The stress at the abutment tooth on all RPD was decreased in functional impression except RPI clasp retained RPD. 2.The stress at the abutment tooth on RPI clasp retained RPD was the most smallest in anatomic impression 3.While load is increase the stress at the abutment tooth was increased, but the change of stress at the buccal side of abutment tooth was not too much in functional impression.
Denture, Partial, Removable*
;
Tooth
10.Sedation and Hemodynamic Stability during Fiberoptic Awake Nasotracheal Intubation: Comparison between Propofol Infusion and Intravenous Boluses of Fentanyl and Midazolam.
Ji Hee LEE ; Sang Wook HAN ; Yu Young KIM ; Kwang Won YUM
Korean Journal of Anesthesiology 1997;33(4):741-749
BACKGROUND: Crucial to the success of fiberoptic awake tracheal intubation is proper preparation of the patient; this technique will work well in most patients when they are quiet and cooperative and have a larynx nonreactive to physical stimuli. We have attempted to ascertain how well these conditions are achieved with a low-dose infusion of propofol, because of its pharmacological profile. METHODS: Thirty patients, physical status by American Society of Anesthesiologists (A. S. A.) I-II, scheduled for oral and maxillofacial surgery, were randomly assigned to receive either propofol infusion 1 mg kg-1 h-1 preceded by a 1 mg kg-1 bolus (Group P) or intravenous fentanyl 1ug kg-1 and midazolam 0.05 mg kg-1 (Group F). These two groups were compared in terms of hemodynamic profile, sedation score, condition for intubation, coughing and swallowing. RESULTS: There were no statistically significant differences in mean arterial blood pressures according to time between two groups. But in Group F, heart rates were significantly increased in immediately after transtracheal injection of lidocaine, immediately before the fiberoscopy was started, 1, 2 minutes after start of fiberoscopy, compared to Group P (p<0.05). The patients in Group P were more sedated than those in Group F (p<0.05) but there were no significant differences in condition for intubation, reflex of coughing and swallowing, duration of fiberoptic intubation. CONCLUSIONS: We conclude that propofol is useful sedative agent in fiberoptic awake intubation with similar efficacy to midazolam and fentanyl but with more profound sedation and stable hemodynamic profile. These represent significant advantages for severe anxious or hypertensive patients and prolonged procedure of intubation.
Arterial Pressure
;
Cough
;
Deglutition
;
Fentanyl*
;
Heart Rate
;
Hemodynamics*
;
Humans
;
Intubation*
;
Larynx
;
Lidocaine
;
Midazolam*
;
Propofol*
;
Reflex
;
Surgery, Oral