The patient was a 24-year-old Korean man with an extensive nevus flammeus over the rigbt buttock, penis, leg, ankle and dorsal aspect of foot. Varicose veins on the flexor aspect of mid-portion of lower extremity of right side are noted remarkable hypertrophy of the soft tissue and bones are also found on the area where hemangioma is associated with them. Radiological examination of spine, pelvic, femur, tibia and fibula bones showed longer and thicker in affected side (right) than unaffected (left), and vertebral bones showed compensatory scoliosis-convexity to the left (normal side)and damage of vertebral bodies at the level of L-3, 4, 5. These are well established and described as Klippel-Trenaunay-Parkes Weber Syndrome by Klippel, Trenaunay and Parkes-Weber. Authors are made extensive review of literatures of the syndrome and discussions on the type, varient, heredity, sex, onset of age, affected location, racial distribution, right name of syndrorne and differential diagnosis of the syndrome.
Ankle ; Brain Stem Infarctions* ; Buttocks ; Diagnosis, Differential ; Femur ; Fibula ; Foot ; Hemangioma ; Heredity ; Humans ; Hypertrophy ; Leg ; Lower Extremity ; Male ; Penis ; Port-Wine Stain ; Spine ; Tibia ; Varicose Veins ; Young Adult

BACKGROUND/AIMS: Gallbladder polyps and colorectal adenomas share many common risk factors; however, their association has never been studied. The aim of this study was to investigate this association in asymptomatic healthy subjects. METHODS: Consecutive asymptomatic subjects who underwent both screening colonoscopy and abdominal ultrasonography at Kyung Hee University Hospital in Gang Dong between July 2010 and April 2011 were prospectively enrolled. The prevalence of colorectal adenoma was compared between subjects with or without gallbladder polyps. Furthermore, a logistic regression analysis was performed to determine the independent risk factors for colorectal adenoma in these subjects. RESULTS: Of the 581 participants, 55 presented with gallbladder polyps and 526 did not have gallbladder polyps. Participants with gallbladder polyps showed a trend toward a higher prevalence of colorectal adenoma than those without gallbladder polyps (52.7% vs. 39.2%, P=0.051). Although the result was not statistically significant, gallbladder polyps were found to be a possible risk factor for colorectal adenoma (odds ratio=1.796, 95% confidence interval=0.986-3.269, P=0.055), even after adjusting for potential confounding factors. There was no difference observed in colorectal adenoma characteristics between the two groups. CONCLUSIONS: Our results suggest a possible association between gallbladder polyps and colorectal adenomas. Future studies with larger cohorts are warranted to further investigate this matter.
Adenoma* ; Cohort Studies ; Colonoscopy ; Colorectal Neoplasms ; Gallbladder* ; Logistic Models ; Mass Screening ; Polyps* ; Prevalence ; Prospective Studies ; Risk Factors ; Ultrasonography