BACKGROUND: Several modalities have been used for the treatment of livedo vasculitis. However, in some cases conspicious morbidity is caused by recurrent painful ulceration resistant to therapy. OBJECTIVE: This study was conducted to determine the effectiveness and adverse effects of the danazol in treatment of livedo vasculitis. METHODS: Nine patients with ulcerative lesions due to livedo vasculitis were included for danazol therapy. Danazol 200mg was administered daily for 4 to 8 weeks. RESULTS: Eight of the patients showed remarkable improvement and were satisfied with this therapy. Significant adverse effects were not observed. CONCLUSION: We suggest that a low dose of danazol may be considered as the first line of treatment and is worthwhile to try in cases recalcitrant to the other treatment.
Danazol* ; Humans ; Ulcer ; Vasculitis*

The ulnar nerve entrapment at the wrist is usually caused by carpal ganglion, occupational neuritis, ulnar artery disease, fractures of the carpal bones, tumors, rheumatioid arthritis, etc. The ganglion is the most common cause of the distal ulnar nerve entrapment. A fort-two years old woman complained of insidious motor weakness of the left hand. The electromyogram revealed distal ulnar nerve palsy. On examination, her sensibility of affected hand was normal; there were no Tinel's sign and palpable mass on the Guyon's canal and palm; there was obvious wasting of all the interossei. On surgical exploration, the deep branch of the ulnar nerve was compressed by a ganglion at the mid-palmar space, not in the Guyon's canal. Four months after removal, the clawing of the 4th and 5th fingers disappeared, and the pinch power of the left hand recovered normally seventeen months later.
Animals ; Arteries ; Arthritis ; Carpal Bones ; Female ; Fingers ; Ganglion Cysts ; Hand ; Hoof and Claw ; Humans ; Paralysis ; Ulnar Nerve Compression Syndromes ; Ulnar Nerve ; Ulnar Neuropathies

During recent 3 years, the authors had treated surgically 31 patients who have had old nerve injuries. 19 patients(21 nerves) of them could be followed for more than 1 year after operation. Of these patients, children were 5 and adults were 14. The elapsed time from the injury were from 3 weeks to 20 months(18 cases under 6months and 3 cases above 6 months). The methods of operation were epineural suture(4 cases), grouped interfascicular suture(8 cases), neurolysis(8cases) and nerve graft(1 case). There were satisfactory or good results in 9 nerves of the 21 old nerve injuries. In 4 of 5 children and 5 of 16 adults, good results were obtained. There were 2, 6 satisfactory or good results in 4 epineural sutures and 8 grouped interfascicular sutures and all poor results in 8 neurolyses. One case treated with nerve graft with sural nerve was showed good result. 9 cases of 18 old injuried nerves under 6 months from injury were good results. All 3 cases over 6 months from injury were poor results.
Adult ; Child ; Humans ; Sural Nerve ; Sutures ; Transplants

BACKGROUND: Although palmoplantar epidermal cysts have long been associated with develop ment following implantation of an epidermal fragment as a result of a penetrating or blunt injury, the pathogenic mechanism is still not fully understood. Since 1987, many cases have been reported in which human papillomavirus(HPV) could be associated with palmoplantar epidermal cysts. OBJECTIVE: In this study, we evaluated the clinicopathological findings of palmoplantar epidermal cysts and investigated them for the presence of HPV in order to examine the role of HPV in the pathogenesis of this disorder in Korea. METHODS: The clinical, histological, immunohistochemical studies were performed on seven cases of plantar cysts, and two cases of palmar cysts. RESULTS: No previous trauma history was seen. Histopathologically, parakeratotic nuclei, or vacuolar strutures within the keratinous mass in the cyst cavity were found. However, we could not find intracytoplasirnic eosinophilic bodies in the wall, the cyst content, or the overlying epidermis. The dyskeratotic keratinocytes were observed in 3 cases. Papillomavirus common antigens were not detected by immunohissochemical staining. CONCLUSIONS: Palmoplantar epidermal cysts in Korea have some different histological features compared to those of HPV 60-associated cases in Japan and we could not detect the immunohistochemical evidence of HPV infection in our cases.
Eosinophils ; Epidermal Cyst* ; Epidermis ; Humans ; Japan ; Keratinocytes ; Korea ; Wounds, Nonpenetrating

Hand injuries in the industries have been steadily increasing in this country in recent years. All structures are damaged when a hand is caught in punch presses, gears or under falling objects. Irreversible loss of blood supply to the part is only real indication for primary amputation. Statistical observations were carried out on 240 patients of hand injuries who were treated at the Deparement of Orthopedic Surgery, College of Medicine, Hanyang University from May, 1972 to April, 1977 and following results were obtained. 1. The peak incidence was in the age group from 11 to 20 years in 83 cases(38.4%) and of the 226 patients, 204(85.0%) were male and 36(15.0%) were female. 2. In general, the incidence of hand injuries per year was annually increased and was much more occurred on April than other months of year. 3. The injured ratio of both hands was almost equal and main causes of hand injury were industrial accident (72.1%), traffic accident(12.9%) and electric accident(6.3%). 4 Most of hand injured patients(81.7%) arrived at our hospital within 6 hours after accidents 5. Of 240 injuries, 78(32.5%) were crushing injury with open comminuted fracture, 39(16.2%) were open fracture and 30(12.5%) were closed fracture. 6. Of injured fingers, 126(51.2%) were mondigit and the remained were polydigits. 7. The most frequency of monodigit injury was index finger(32.5%) and of polydigits injury was middle finger(28.2%) 8. In mondigit amputation, index finger were generally amputated at metacarpo-phalangeal joint and middle finger at proximal phalangeal level. 9. Of 457 injuries with facture, 213(46.6%) were treated by debridement and primary suture, and 94 (20.6%) by debridement and open reduction with Kirschner wire fixation. 10. Of 240 patients, 46 cases(19.2%) were infected and the main causative organisms were pseudomonas aeruginosa (41.3%), Staphylococcus aureus(17.3%) and Alkaligenus fecalis(10.9%).
Accidental Falls ; Accidents, Occupational ; Amputation ; Clinical Study ; Debridement ; Female ; Fingers ; Fractures, Closed ; Fractures, Comminuted ; Fractures, Open ; Hand Injuries ; Hand ; Humans ; Incidence ; Joints ; Male ; Orthopedics ; Pseudomonas aeruginosa ; Staphylococcus ; Sutures

Ex.traosseous osteogenic sarcoma is exceedingly rare although bone formation occurs commonly in different reactive processes or neoplasms. Most of this tumors occurred in the lower extremities of middle aged people. The overall prognosis is grave and local recurrence following simple local excision possibly contributes to the poor prognosis. An agressive surgical approach including major amputation is recommended as the primary form of treatment. We have experienced a case of extraosseous osteogenic sarcoma of left gluteal region at the site of therapeutic irradiation for cervical carcinoma 16 years previously.
Amputation ; Buttocks ; Humans ; Lower Extremity ; Middle Aged ; Osteogenesis ; Osteosarcoma ; Prognosis ; Recurrence

Rumex japonicus Houttuyn are ubiquitous plants, which are found in marshes or in wet areas. The root of Rumex japonicus Houttuyn has been used for the treatment of skin diseases including fungal infections of the skin since older times in Japan and China. This study was undertaken to investigate the antifungal activity of the alcoholbenzene extract of Rumex japonicus Houttuyn in vitro. During this experiment the extracts of Rumex japonicus Houttuyn were diluted seriaIly in the Sabouraud's dextrose agar and fungal mats or fungal suspensions of isolated strains of dermatophytes were inoculated into each medium containing different concentrations of test materials. Then their growth was observed for 2 weeks or 10 days at room temperature. (countinued...)
Agar ; Arthrodermataceae ; China ; Glucose ; Japan ; Rumex* ; Skin ; Skin Diseases ; Suspensions ; Wetlands

No abstract available.
Temporomandibular Joint*

A clinical study was made on 148 cases of cutaneous malignant tumors that visited the Department of Dermatology at Seoul National University Hospital during a 11-year period from 1973 to 1983. The results were summarized as follows: 1) The incidence of cutaneous malignant tumors in the total number of outpatients visiting the Department of Derrnatology was 0. 025g. 2) There were 90 cases of male (60. 8p,) and 58 cases of female (39. 2g). The ratio of male to female was l. 55: l. Among the 148 cases of cutaneous malignant tumors, the most frequently observed type was basal cell carcinoma, 58 cases (3j.2 p:). The next most frequent types were squamous cell carcinoma, 42 cases(28. 4g) and malignant melanoma, ]1 cases (7. 4g). We described the clinical characteristics of the patients with basal cell carcinoma, squamous cell carcinoma and malignant melanoma that have been observed.
Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Dermatology ; Female ; Humans ; Incidence ; Male ; Melanoma ; Outpatients ; Seoul

BACKGROUND: Punch grafts and punch elevation can be useful for the correction of deep pitting or round atrophic acne scars. The traditional punch elevation technique gives inadequete results. Even round scars leave a retraction space and do not always heal well. OBJECTIVES & METHODS: To improve the cosmetic results of traditional punch elevation and thus promote the use of punch elevation instead of punch grafting, we performed punch elevation with purse-string sutures on 10 patients with acne, pox & atrophic scars. We performed dermabrasion or CO2 laserbrasion after 8 weks. RESULTS: Nicely fit margins of the punch elevation site with purse-string suture left no retraction spaces and enhanced the aesthetic results. CONCLUSION: Punch elevation is a simple, satisfactory method of improving cosmetic results in scars. The Purse-string suture technique can make it a more valuable tool for surgery of facial scars, because it overcomes of disadvantages the punch elevation.
Acne Vulgaris* ; Cicatrix* ; Dermabrasion ; Humans ; Suture Techniques ; Sutures* ; Transplants