1.Immunohistochemical Study on Expression of CD34 in Basal Cell Carcinomas and Trichoepitheliomas.
Kwang Ho KIM ; Ho Gyun LEE ; Jong Min KIM
Korean Journal of Dermatology 1995;33(4):650-654
BACKGROUND: The differentiation between basal cell carcinoma(BCC) and trichoepithelioma(TE) is sometimes difficult clinically and histologically, and their differentiation is important since their treatment and prognosis are sometimes different. OBJECTIVE: Our purpose was to investigate whether there was a difference in CD34 staining patterns in the stromas (immediate and distant stromas from the tumor lobules) of BCC and TE, since the histopathologic characteristics of the stromas are one of the most important features to differentiate the two tumor. METHOD: We perfomed immunoperoxidase staining(modified ABC technique) by using a monoclonal anti CD34 antibody(QBEND10, IgG1) on the formalin-fixed, paraffin-embedded biopsy specimens of 11 BCC as and 10 TEs. RESULTS: 1. In the immediate strcimas, spindle-shaped cells were stained in 4 out of ll cases of BCC and in 9 out of 10 cases of TE. However, the staining patterns observed in the 4 cases of BCC were all loosely scattered, week staining, while those of the 9 cases of TE were all densely compact, strong staining. CD34 was not expressed in one case of TE. 2. In the distant stromas, all cases of BCC and TE showed staining of loosely scattered spindle-shaped cells, and there was no difference in staining patterns of the two tumors. 3. Papillary mesenchymed bodies were observed in 8 cases of TE and in none of BCC, and they expressed CD34 focally. CONCLUSION: CD34 sta ining patterns of the immediate peritumoral stromas of BCCs and TEs were different and could differentiate the two tumors.
Biopsy
;
Carcinoma, Basal Cell*
;
Prognosis
2.Use of Alternative Medicine by Patients with Psoriasis.
Sang Ho NAM ; Ho Gyun LEE ; Kwang Ho KIM ; Kwang Joong KIM ; Chong Ju LEE
Annals of Dermatology 2001;13(1):1-6
BACKGROUND: Psoriasis is a disabling and intractable disease influencing the psychosocial life of the patients. Patients who are frustrated with orthodox medicine may explore alternative therapies. OBJECTIVE: This study was done to research on the actual condition of the use of alternative medicine in the patients with psoriasis. METHODS: A self-administered questionnaire was constructed, and was given to the patients to answer our questions. RESULTS: Among 128 patients with psoriasis, 61 (47.7%) reported previous use of one or more forms of alternative medicine. The absence of satisfactory long-term effects of physician-provided therapy was the main reason for patients trying alternative medicine. Persons without skin s disease and the mass media were the main sources of information on alternative medicine. CONCLUSION: Alternative therapies were widely utilized by subjects participating in this study, and dermatologists need to be aware of alternative treatments employed by their patients.
Complementary Therapies*
;
Humans
;
Mass Media
;
Psoriasis*
;
Skin
3.A Case of Kimura's Disease with an Unusual Location and Clinical Manifestation.
Ho Gyun LEE ; Bang Soon KIM ; Ai Young LEE ; Kwang Hyun CHO ; Yoo Shin LEE
Annals of Dermatology 1990;2(2):145-148
Kimura's disease is a chronic inflammatory condition of unknown cause. It usually appears as a painless nodule in the head and neck region often associated with regional lymphadenopathy, but there have rarely been reports of penile involvement or clinical presentation as an ulcerative plaque. We present a case of Kimura's disease occurring on the penile shaft as an ulcerative plaque in a 44-year-old man. A vesicular eruption had occurred on his penile shaft followed by an ulcerative plaque for 2 months. He had suffered from recurrent regional lymphadenopathy for 15 years and he had also exhibited intermittent eosinophilia. Histopathologic findings revealed diffuse eosinophilic infiltration in the dermis of the skin and eosmophilic abscesses in the lymphoid follicles of the mguinal lymph node. After short-term systemic steroid therapy and local injection of triamcinolone acetonide, the ulcerative plaque was healed.
Abscess
;
Adult
;
Dermis
;
Eosinophilia
;
Eosinophils
;
Head
;
Humans
;
Lymph Nodes
;
Lymphatic Diseases
;
Neck
;
Skin
;
Triamcinolone Acetonide
;
Ulcer
4.A Case of Primary Cutaneous Marginal Zone B-cell Lymphoma.
Jae Wang KIM ; Ho Gyun LEE ; Kwang Joong KIM ; Jong Min KIM ; Chong Ju LEE
Annals of Dermatology 1999;11(2):124-128
We herein present a rare case of a 42-year-old man with primary cutaneous marginal zone lymphoma(MZL) of the B-cell type on his shin. MZL is known to be the cutaneous counterpart of MALT(mucosa-associated lymphatic tissue) lymphoma. Histopathologically, MZL is characterized by multi-nodular infiltrates of centrocyte-like and centroblast-like marginal cells with bottom-heavy patterns, lymphoplasmacytoid differentiation, typical distribution of tumor cells in the marginal zone and follicular colonization by tumor cells. This B-cell lymphoma of a benign grade should be differentiated from mantle cell lymphoma and follicular center cell lymphoma.
Adult
;
B-Lymphocytes
;
Colon
;
Humans
;
Lymphoma
;
Lymphoma, B-Cell
;
Lymphoma, B-Cell, Marginal Zone*
;
Lymphoma, Mantle-Cell
5.A Case of Pearly Penile Papules.
Jong Hoon SHIN ; Kwang Soo HAN ; Ho Gyun LEE ; Jong Min KIM
Korean Journal of Dermatology 1998;36(6):1122-1124
Pearly penile papules are small, smooth, dome-shaped, grayish to skin-colored papules, that are arranged in one or several rows. These are commonly located circumferentially on the corona and sulcus of the glans penis. A 36-year-old male patient had had asymptomatic numerous pearly smooth 1 * 1mm -sized dome-shaped papules for several months. A Histopathological examination revealed an increased number of fibroblasts on the papillary dermis, vascular proliferation and a mild lymphocytic infiltration. We diagnosed the condition as pearly penile papules. No treatment other than reassurance was given. We report, herein, a case of pearly penile papules.
Adult
;
Dermis
;
Fibroblasts
;
Humans
;
Male
;
Penis
6.A Case of Nerve Cheath Myxoma.
Kwang Soo HAN ; Jong Hun SHIN ; Ho Gyun LEE ; Jong Min KIM
Korean Journal of Dermatology 2000;38(5):694-697
No Abstract Available.
Myxoma*
7.The value of computerized axial tomography of the brain in children with central nervous system disorders.
Young Gyun LEE ; Dae Sung HWANG ; Kwang Soo OH ; Hyang Seuk YOON ; Jong Duck KIM
Journal of the Korean Pediatric Society 1991;34(10):1409-1416
No abstract available.
Brain*
;
Central Nervous System Diseases*
;
Central Nervous System*
;
Child*
;
Humans
8.The value of computerized axial tomography of the brain in children with central nervous system disorders.
Young Gyun LEE ; Dae Sung HWANG ; Kwang Soo OH ; Hyang Seuk YOON ; Jong Duck KIM
Journal of the Korean Pediatric Society 1991;34(10):1409-1416
No abstract available.
Brain*
;
Central Nervous System Diseases*
;
Central Nervous System*
;
Child*
;
Humans
9.Evaluation of the dilshie clip versus bipolar electrocoagulation via laparoscopy.
Hyun Mo KWAK ; Sei Kwang KIM ; Heung Gyun KIM ; Mi Sook LEE
Korean Journal of Obstetrics and Gynecology 1992;35(5):694-700
No abstract available.
Electrocoagulation*
;
Laparoscopy*
10.A Case of Lupus Erythematosus Panniculitis with Infiltration of Atypical Lymphocytes.
Sung Ju PARK ; Kwang Soo HAN ; Ho Gyun LEE ; Jong Min KIM
Korean Journal of Dermatology 1998;36(6):1074-1077
Lupus erythematosus panniculitis is a rare variant of lupus erythematosus primarily involving a panniculus with or without discoid lupus erythematosus in the overlying skin. A 34-year-old woman showed multiple, variable-sized, indurated subcutaneous nodules on both her upper arms and axillae. A Histopathological examination revealed lobular panniculitis with infiltration of several hyperchromatic atypical large lymphocytes. The infiltrated cells were positively stained with LCA, UCHL-1, CD4, CD8, but not with CD20 and CD68. A T cell receptor -chain gene and immunoglobulin heavy chain gene rearrangement study showed no monoclonality. The result of an ANA test was positive at 1: 40 in a homogeneous pattern. Skin lesions were improved by combined therapy with daily hydroxychloroquine 400mg and prednisolone 10mg in a week and after 6weeks, resolved with atrophic depressed scars. After 4 months, she complained of symptoms of the Raynaud phenomenon and was managed by nifedipine. There has been no recurrence during follow-up for 7 months.
Adult
;
Arm
;
Axilla
;
Cicatrix
;
Female
;
Follow-Up Studies
;
Gene Rearrangement
;
Humans
;
Hydroxychloroquine
;
Immunoglobulin Heavy Chains
;
Lupus Erythematosus, Discoid
;
Lymphocytes*
;
Nifedipine
;
Panniculitis
;
Panniculitis, Lupus Erythematosus*
;
Prednisolone
;
Raynaud Disease
;
Receptors, Antigen, T-Cell
;
Recurrence
;
Skin